Rubinstein-Taybi Syndrome

A chromosomal disorder characterized by MENTAL RETARDATION, broad thumbs, webbing of fingers and toes, beaked nose, short upper lip, pouting lower lip, agenesis of corpus callosum, large foramen magnum, keloid formation, pulmonary stenosis, vertebral anomalies, chest wall anomalies, sleep apnea, and megacolon. The disease has an autosomal dominant pattern of inheritance and is associated with deletions of the short arm of chromosome 16 (16p13.3).

Synonym
Rubinstein-Taybi Syndrome

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	16 (30.77)	23.3326
1990's	8 (15.38)	12.5806
2000's	9 (17.31)	18.1394
2010's	15 (28.85)	28.8240
2020's	4 (7.69)	9.53

Drug	Relationship Strength	Studies
salicylic acid	low	2
cytosine	low	1
glycine	low	1
nitrous oxide	low	2
valproic acid	low	1
isoflurane	low	1
2-propanol	low	1
khellin	low	12
propofol	low	3
rolipram	low	1
sevoflurane	low	3
succinylcholine	low	1
thyroxine	low	2
prednisone	low	1
triiodothyronine	low	1
serine	low	1
aspartic acid	low	1
lysine	low	1
technetium	low	1
triamcinolone	low	1
atracurium	low	1
remifentanil	low	2
5-methylcytosine	low	1
5-hydroxymethylcytosine	low	1
glycogen	low	1
trichostatin a	low	1
isomethyleugenol	low	3
thiopental	low	1
cystine	low	1
phenylephrine hydrochloride	low	1
dynorphins	low	1
piperidines	low	2

Protein Targets (450)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
hypoxia-inducible factor 1 alpha subunit	1	0	0	1
RAR-related orphan receptor gamma	7	0	0	7
GLI family zinc finger 3	9	0	0	9
AR protein	7	0	0	7
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
retinoic acid nuclear receptor alpha variant 1	6	0	0	6
retinoid X nuclear receptor alpha	3	0	0	3
estrogen nuclear receptor alpha	11	0	0	11
peroxisome proliferator-activated receptor delta	2	0	0	2
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	8	0	0	8
activating transcription factor 6	2	0	0	2
v-jun sarcoma virus 17 oncogene homolog (avian)	4	0	0	4
Histone H2A.x	2	0	0	2
thyroid hormone receptor beta isoform a	5	0	0	5
heat shock protein beta-1	4	0	0	4
nuclear factor erythroid 2-related factor 2 isoform 1	8	0	0	8
lamin isoform A-delta10	8	0	0	8
Voltage-dependent calcium channel gamma-2 subunit	1	0	0	1
Glutamate receptor 2	1	0	0	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	3	0	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	3	0	0	3
Chain A, Ferritin light chain	4	0	0	4
phosphopantetheinyl transferase	2	0	0	2
arylsulfatase A	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	8	0	0	8
Bloom syndrome protein isoform 1	5	0	0	5
cytochrome P450 2C19 precursor	2	0	0	2
lethal factor (plasmid)	2	0	0	2
Metabotropic glutamate receptor 6	0	0	1	1
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	3	0	4
Carbonic anhydrase 2	0	3	0	4
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	0	3	1	4
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	3	1	4
Glutamate receptor ionotropic, NMDA 2B	0	3	1	4
Glutamate receptor ionotropic, NMDA 2C	0	3	1	4
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	3	1	4
Glutamate receptor ionotropic, NMDA 3B	0	3	1	4
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	0	3	1	4
NPYLR7B	0	0	1	1
Amine oxidase [flavin-containing] A	0	0	1	1
Small conductance calcium-activated potassium channel protein 3	0	1	1	2
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
thioredoxin reductase	7	0	0	7
pregnane X receptor	3	0	0	3
NFKB1 protein, partial	2	0	0	2
GALC protein	3	0	0	3
TDP1 protein	6	0	0	6
Thrombopoietin	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	5	0	0	5
progesterone receptor	5	0	0	5
nonstructural protein 1	1	0	0	1
glucocorticoid receptor [Homo sapiens]	6	0	0	6
estrogen-related nuclear receptor alpha	9	0	0	9
farnesoid X nuclear receptor	4	0	0	4
pregnane X nuclear receptor	6	0	0	6
G	4	0	0	4
vitamin D (1,25- dihydroxyvitamin D3) receptor	2	0	0	2
IDH1	4	0	0	4
thyroid stimulating hormone receptor	2	0	0	2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
chromobox protein homolog 1	5	0	0	5
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
thyroid hormone receptor beta isoform 2	5	0	0	5
mitogen-activated protein kinase 1	3	0	0	3
serine/threonine-protein kinase mTOR isoform 1	1	0	0	1
geminin	6	0	0	6
survival motor neuron protein isoform d	4	0	0	4
cytochrome P450 3A4 isoform 1	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	5	2	2	9
Solute carrier family 22 member 2	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
Solute carrier family 22 member 3	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Interferon beta	6	0	0	6
HLA class I histocompatibility antigen, B alpha chain	4	0	0	4
Sex hormone-binding globulin	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	0	1	1
Androgen receptor	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	5	2	2	9
Gamma-aminobutyric acid receptor subunit delta	5	2	2	9
Gamma-aminobutyric acid receptor subunit gamma-2	5	2	2	9
Gamma-aminobutyric acid receptor subunit alpha-5	5	2	2	9
Gamma-aminobutyric acid receptor subunit alpha-3	5	2	2	9
Gamma-aminobutyric acid receptor subunit gamma-1	5	2	2	9
Gamma-aminobutyric acid receptor subunit alpha-2	5	2	2	9
Gamma-aminobutyric acid receptor subunit alpha-4	5	2	2	9
Gamma-aminobutyric acid receptor subunit gamma-3	5	2	2	9
Gamma-aminobutyric acid receptor subunit alpha-6	5	2	2	9
C-8 sterol isomerase	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	1	0	1
Nuclear receptor ROR-gamma	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	5	2	2	9
Gamma-aminobutyric acid receptor subunit beta-3	5	2	2	9
Gamma-aminobutyric acid receptor subunit beta-2	5	2	2	9
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	1	0	1
Solute carrier family 22 member 1	0	2	0	2
GABA theta subunit	5	2	2	9
Inositol hexakisphosphate kinase 1	4	0	0	4
Sigma non-opioid intracellular receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	5	2	2	9
Solute carrier family 22 member 2	0	2	0	2
cytochrome P450 2C9, partial	4	0	0	4
Deoxycytidine kinase	0	0	0	1
Mas-related G-protein coupled receptor member X2	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent glycine transporter 1	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	2	0	2
Serine racemase	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Sodium- and chloride-dependent glycine transporter 2	0	1	0	1
Cellular tumor antigen p53	8	0	0	8
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
glp-1 receptor, partial	5	0	0	5
USP1 protein, partial	6	0	0	6
nuclear receptor subfamily 1, group I, member 3	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
cytochrome P450 2D6	1	0	0	1
aryl hydrocarbon receptor	3	0	0	3
cytochrome P450 2D6 isoform 1	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
importin subunit beta-1 isoform 1	1	0	0	1
snurportin-1	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
peripheral myelin protein 22	3	0	0	3
histone acetyltransferase KAT2A isoform 1	3	0	0	3
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1A2	0	3	0	3
Cytochrome P450 3A4	0	1	0	1
Cytochrome P450 2D6	0	2	0	2
Cytochrome P450 2C9	0	3	0	3
Cytochrome P450 2C19	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
Glutathione reductase, mitochondrial	0	2	0	2
Cationic amino acid transporter 3	0	1	0	1
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
peroxisome proliferator activated receptor gamma	4	0	0	4
beta-2 adrenergic receptor	1	0	0	1
lysosomal alpha-glucosidase preproprotein	1	0	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
Vpr	1	0	0	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Neuronal acetylcholine receptor subunit alpha-4	1	0	0	1
Neuronal acetylcholine receptor subunit beta-2	1	0	0	1
Spike glycoprotein	2	0	0	2
thioredoxin glutathione reductase	2	0	0	2
estrogen receptor 2 (ER beta)	1	0	0	1
vitamin D3 receptor isoform VDRA	2	0	0	2
nuclear receptor ROR-gamma isoform 1	1	0	0	1
Glucocorticoid receptor	0	4	1	5
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
Chain A, Ferritin light chain	0	0	1	1
GLS protein	1	0	0	1
caspase 7, apoptosis-related cysteine protease	1	0	0	1
thyroid stimulating hormone receptor	1	0	0	1
caspase-3	1	0	0	1
D(1A) dopamine receptor	2	0	0	2
DNA polymerase iota isoform a (long)	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
Fatty-acid amide hydrolase 1	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	2
5-hydroxytryptamine receptor 4	0	2	0	2
Aldo-keto reductase family 1 member B1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	0	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	2	1	3
Gamma-aminobutyric acid receptor subunit beta-1	0	1	1	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	0	0	0	2
Prostaglandin G/H synthase 1	0	3	0	3
Sodium-dependent noradrenaline transporter	0	3	0	3
Sodium- and chloride-dependent GABA transporter 1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	2	1	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	2	0	2
Sodium- and chloride-dependent GABA transporter 3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	1	2
5-hydroxytryptamine receptor 2B	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-2	0	1	1	2
Sodium- and chloride-dependent betaine transporter	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	1	2
Fatty-acid amide hydrolase 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	1	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Mu-type opioid receptor	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	1	3
Chain A, Cruzipain	1	0	0	1
flap endonuclease 1	1	0	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	1	0	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	2	0	2
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A	0	1	0	1
Retina-specific copper amine oxidase	0	1	0	1
cGMP-specific 3',5'-cyclic phosphodiesterase	0	2	0	3
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B	0	1	0	1
Renin	0	1	0	1
Tumor necrosis factor	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	4
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	1	4
Adenosine receptor A2b	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Bifunctional epoxide hydrolase 2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	2	0	3
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	1	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	3
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	2	0	3
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	3
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Endothelin-1 receptor	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Phosphodiesterase	0	1	0	1
Protein cereblon	0	2	0	2
Phosphodiesterase	0	1	0	1
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 7B	0	1	0	1
Phosphodiesterase	0	1	0	1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	0	1	0	1
chaperonin-containing TCP-1 beta subunit homolog	1	0	0	1
Estrogen receptor beta	0	0	0	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Polyphenol oxidase 2	0	1	0	2
Carbonic anhydrase 12	0	1	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Bile salt export pump	0	2	0	2
Bile salt export pump	0	3	0	3
Albumin	0	1	0	1
Polymerase acidic protein	0	0	1	1
Carbonic anhydrase 3	0	1	0	1
Stromelysin-1	0	0	1	1
Tyrosine-protein phosphatase YopH	0	1	0	1
High mobility group protein B1	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Acetylcholinesterase	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Carbonic anhydrase 7	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	0	1
Xanthine dehydrogenase/oxidase	0	1	0	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	0	1
Carbonic anhydrase 9	0	1	0	1
Carbonic anhydrase	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
DNA polymerase kappa isoform 1	2	0	0	2
Acetylcholinesterase	0	1	0	1
Pyruvate kinase PKM	0	0	1	1
Neutral amino acid transporter A	0	1	0	1
Cholinesterase	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Acetylcholinesterase	0	1	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
apical membrane antigen 1, AMA1	2	0	0	2
EWS/FLI fusion protein	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
DNA polymerase eta isoform 1	1	0	0	1
Solute carrier organic anion transporter family member 1A4	0	1	0	3
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier organic anion transporter family member 1A5	0	0	0	2
Rap guanine nucleotide exchange factor 3	1	0	0	1
Transthyretin	0	1	0	3
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Retinoic acid receptor RXR-alpha	0	0	2	2
UDP-glucuronosyltransferase 1A1	0	1	0	1
Peroxisome proliferator-activated receptor gamma	0	0	4	4
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 1A2	0	0	0	2
Solute carrier organic anion transporter family member 1A3	0	0	0	2
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Bile acid receptor	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
Solute carrier organic anion transporter family member 1B1	0	0	0	2
SMAD family member 2	1	0	0	1
ATAD5 protein, partial	2	0	0	2
SMAD family member 3	1	0	0	1
Smad3	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
muscleblind-like protein 1 isoform 1	2	0	0	2
Cytochrome P450 2J2	0	1	0	1
ATPase family AAA domain-containing protein 5	2	0	0	2
Ataxin-2	2	0	0	2
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Chain A, Histone deacetylase 7a	0	1	0	1
Histone deacetylase 8	0	1	0	1
PPM1D protein	1	0	0	1
Microtubule-associated protein tau	1	0	0	1
regulator of G-protein signaling 4	1	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
glucocerebrosidase	2	0	0	2
unnamed protein product	0	0	0	1
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
Histone deacetylase 1	0	2	0	2
Histone deacetylase 3	0	4	0	6
5-hydroxytryptamine receptor 3A	0	1	0	1
Histone deacetylase 3	0	1	0	1
Plasma kallikrein	0	1	0	1
Integrin beta-3	0	1	0	1
Integrin alpha-IIb	0	1	0	1
Coagulation factor VII	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Vitamin D3 receptor	0	1	0	1
Tissue factor	0	2	0	2
Adenosine receptor A1	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Histamine H2 receptor	0	1	0	1
Histone deacetylase 4	0	4	1	8
Histone deacetylase 2	0	1	0	1
Histone deacetylase 1	0	4	2	8
Splicing factor 3B subunit 3	0	1	0	1
Histone deacetylase 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Histone deacetylase	0	1	0	1
Histone deacetylase 4	0	1	0	1
Polyamine deacetylase HDAC10	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase-like amidohydrolase	0	2	0	2
Histone deacetylase 7	0	1	0	1
NAD-dependent protein deacetylase sirtuin-6	0	1	1	2
Histone deacetylase 8	0	1	0	1
Histone deacetylase 7	0	4	0	6
Histone deacetylase 11	0	1	0	1
Histone deacetylase 2	0	4	1	7
HD2 type histone deacetylase HDA106	0	2	0	2
Polyamine deacetylase HDAC10	0	4	0	6
Histone deacetylase 11	0	4	0	6
Histone deacetylase 9	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
Histone deacetylase 8	0	4	0	6
Histone deacetylase 6	0	4	1	7
Histone deacetylase 9	0	4	0	6
Histone deacetylase 5	0	4	0	6
Histone deacetylase	0	1	0	1
Nuclear receptor corepressor 2	0	2	0	2
Histone deacetylase 6	0	1	0	1
Histone deacetylase 5	0	1	0	1
Histone deacetylase	0	1	0	1
neuropeptide S receptor isoform A	1	0	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Prothrombin	0	0	1	1
Androgen receptor	0	1	0	1
Thyroid hormone receptor beta	0	1	0	1
Adenosine receptor A1	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Solute carrier organic anion transporter family member 1C1	0	1	0	1
Solute carrier organic anion transporter family member 1B3	0	0	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Luciferase	1	0	0	1
Cocaine esterase	0	1	0	1
Cytochrome P450 2A6	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	2
UDP-glucuronosyltransferase 1-6	0	0	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research

Studies (52)

Protein Targets (450)

Rubinstein-Taybi Syndrome

Synonyms(1)

Research

Studies (52)

Drugs Studied (38)

Protein Targets (450)