Page last updated: 2024-10-30

khellin and Rubinstein-Taybi Syndrome

khellin has been researched along with Rubinstein-Taybi Syndrome in 12 studies

Khellin: A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)
khellin : A furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator.

Rubinstein-Taybi Syndrome: A chromosomal disorder characterized by MENTAL RETARDATION, broad thumbs, webbing of fingers and toes, beaked nose, short upper lip, pouting lower lip, agenesis of corpus callosum, large foramen magnum, keloid formation, pulmonary stenosis, vertebral anomalies, chest wall anomalies, sleep apnea, and megacolon. The disease has an autosomal dominant pattern of inheritance and is associated with deletions of the short arm of chromosome 16 (16p13.3).

Research Excerpts

ExcerptRelevanceReference
"Keloids are proliferative fibrous growths resulting from excessive tissue response to skin trauma."2.50Keloids in Rubinstein-Taybi syndrome: a clinical study. ( de Jong, D; Hennekam, RC; Houge, G; Peters, DJ; Shaw, AC; van Belzen, MJ; van de Kar, AL, 2014)
"The array of malignant neoplasms does not suggest an etiology or pathogenesis in common."1.28Keloids and neoplasms in the Rubinstein-Taybi syndrome. ( Miller, RW; Rubinstein, JH; Siraganian, PA, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19905 (41.67)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's3 (25.00)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Snehi, S1
Kaur, A1
Chaudhry, C1
Kaushik, S1
Kuwabara, J1
Akita, S1
Sato, M1
Watanabe, K1
Tanigawa, K1
Matsuno, Y1
Abe, Y1
Kikuchi, S1
Yoshida, M1
Koga, S1
Ishimaru, K1
Watanabe, Y1
Yagi, Y1
Kuwatsuka, Y1
Asai, M1
Honda, M1
Utani, A1
van de Kar, AL1
Houge, G1
Shaw, AC1
de Jong, D1
van Belzen, MJ1
Peters, DJ1
Hennekam, RC1
Lacombe, D1
Morice-Picard, F1
Selmanowitz, VJ1
Stiller, MJ1
Goodfellow, A1
Emmerson, RW1
Calvert, HT1
Hendrix, JD1
Greer, KE1
Rao, SK1
Fan, DS1
Pang, CP1
Li, WW1
Ng, JS1
Good, WV1
Lam, DS1
Kurwa, AR1
Siraganian, PA1
Rubinstein, JH1
Miller, RW1
Sammartino, A1
Cerbella, R1
Lembo, G1
Federico, A1
Loffredo, L1

Reviews

1 review available for khellin and Rubinstein-Taybi Syndrome

ArticleYear
Keloids in Rubinstein-Taybi syndrome: a clinical study.
    The British journal of dermatology, 2014, Volume: 171, Issue:3

    Topics: Age of Onset; Cohort Studies; Female; Humans; Keloid; Male; Rubinstein-Taybi Syndrome; Surveys and Q

2014

Other Studies

11 other studies available for khellin and Rubinstein-Taybi Syndrome

ArticleYear
Congenital glaucoma as a presenting feature of Rubinstein-Taybi syndrome in an infant with a novel pathogenic variant in the
    BMJ case reports, 2023, Jan-18, Volume: 16, Issue:1

    Topics: CREB-Binding Protein; Frameshift Mutation; Glaucoma; Humans; Hydrophthalmos; Infant; Keloid; Male; M

2023
Paraovarian Cyst Torsion in a Patient with Rubinstein-Taybi Syndrome: A Case Report.
    Journal of Nippon Medical School = Nippon Ika Daigaku zasshi, 2021, Jun-30, Volume: 88, Issue:3

    Topics: Abdominal Pain; Adolescent; Cystectomy; Fallopian Tube Diseases; Female; Hirsutism; Humans; Keloid;

2021
Coexistence of keloids and pilomatricoma in a patient with Rubinstein-Taybi syndrome.
    Dermatology online journal, 2018, Jan-15, Volume: 24, Issue:1

    Topics: Adult; beta Catenin; Cyclic AMP Response Element-Binding Protein; Humans; Keloid; Male; Pilomatrixom

2018
Rare genetic diseases, signalling pathways, and keloid scar formation.
    The British journal of dermatology, 2014, Volume: 171, Issue:3

    Topics: Female; Humans; Keloid; Male; Rubinstein-Taybi Syndrome

2014
Rubinstein-Taybi syndrome. Cutaneous manifestations and colossal keloids.
    Archives of dermatology, 1981, Volume: 117, Issue:8

    Topics: Abnormalities, Multiple; Adult; Female; Humans; Keloid; Rubinstein-Taybi Syndrome; Skin; Skin Abnorm

1981
Rubinstein-Taybi syndrome and spontaneous keloids.
    Clinical and experimental dermatology, 1980, Volume: 5, Issue:3

    Topics: Abnormalities, Multiple; Adult; Humans; Keloid; Male; Rubinstein-Taybi Syndrome

1980
Rubinstein-Taybi syndrome with multiple flamboyant keloids.
    Cutis, 1996, Volume: 57, Issue:5

    Topics: Adult; Chromosome Aberrations; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 1

1996
Bilateral congenital corneal keloids and anterior segment mesenchymal dysgenesis in a case of Rubinstein-Taybi syndrome.
    Cornea, 2002, Volume: 21, Issue:1

    Topics: Anterior Eye Segment; Corneal Diseases; Eye Abnormalities; Humans; Infant; Keloid; Keratoplasty, Pen

2002
Rubinstein-Taybi syndrome and spontaneous keloids.
    Clinical and experimental dermatology, 1979, Volume: 4, Issue:2

    Topics: Abnormalities, Multiple; Adult; Female; Humans; Keloid; Rubinstein-Taybi Syndrome

1979
Keloids and neoplasms in the Rubinstein-Taybi syndrome.
    Medical and pediatric oncology, 1989, Volume: 17, Issue:6

    Topics: Abnormalities, Multiple; Adolescent; Adult; Child; Child, Preschool; Female; Humans; Infant; Infant,

1989
[Rubinstein-Taybi syndrome with multiple keloids].
    Journal francais d'ophtalmologie, 1986, Volume: 9, Issue:11

    Topics: Abnormalities, Multiple; Adolescent; Female; Humans; Keloid; Pedigree; Phenotype; Rubinstein-Taybi S

1986