Adenosarcoma

A malignant neoplasm arising simultaneously or consecutively in mesodermal tissue and glandular epithelium of the same part. (Stedman, 25th ed)

Synonym
Adenosarcoma

Excerpt	Reference
"Müllerianadenosarcoma is a rare pelvic malignancy that most commonly arises from the endometrium."	( Curtin, JP; Hines, BJ; Mittal, K; Muggia, FM; Porges, RF, 2002)
"Uterine mullerian adenosarcoma is a rare tumor without specific clinical symptoms and signs."	( Guo, LN; Han, XY; Huang, HF; Pan, LY; Sheng, K; Wan, XR; Xiang, Y, 2010)
"Müllerian adenosarcoma is a rare biphasic tumor in young women."	( Bae, JH; Kim, DC; Lee, SJ; Namkoong, SE; Park, JS, 2010)
"Adenosarcoma is a rare tumour which usually originates from endometrium."	( Aghili, F; Akhavan Tafti, M; Akhavan, A; Navabii, H, 2012)
"Uterine adenosarcoma is an extremely rare uterine malignancy, and the utility of chemotherapy in this disease is not well defined."	( Jones, RL; Loggers, ET; Pollack, SM; Rodler, ET; Schroeder, BA, 2013)
"Uterine adenosarcomas are rare malignant gynaecological tumours."	( De Wilde, RL; Krentel, H, 2016)

Excerpt	Reference
"Uterine adenosarcoma has low malignant potential, except in cases with sarcomatous overgrowth (SOG) and a high-grade morphology."	( Akcay, EY; Atilgan, AO; Ayhan, A; Haberal Reyhan, AN; Ozen, O, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	8 (19.51)	12.5806
2000's	19 (46.34)	18.1394
2010's	10 (24.39)	28.8240
2020's	4 (9.76)	9.53

Drug	Relationship Strength	Studies
1,2-dimethylhydrazine	low	1
dapi	low	1
fluorouracil	low	1
ifosfamide	low	5
indole-3-carbinol	low	1
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1
activins	low	1
carbachol	low	1
etiocholanolone	low	1
androstenedione	low	1
medroxyprogesterone acetate	low	2
dihydrotestosterone	low	1
gestrinone	low	1
etoposide	low	2
epirubicin	low	1
2-amino-3-methylimidazo(4,5-f)quinoline	low	1
finasteride	low	1
ecteinascidin 743	low	1
androstane-3,17-dione, (5alpha)-isomer	low	1
bromochloroacetic acid	low	2
tamoxifen	low	11
17-n,n-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one	low	1
lenvatinib	low	1
bleomycetin	low	1
gastrins	low	1
transforming growth factor beta	low	1
cyclin d1	low	1
dacarbazine	low	2

Protein Targets (702)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Androgen receptor	0	12	1	13
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	4	0	4
Androgen receptor	0	2	2	4
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	4	0	4
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	2	0	2
3-oxo-5-alpha-steroid 4-dehydrogenase 2	0	4	0	4
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	3	0	0	3
Chain B, HADH2 protein	3	0	0	3
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Chain A, Cruzipain	2	0	0	2
Chain A, Methyltransferase Wbdd	0	1	0	1
thioredoxin reductase	3	0	0	3
15-lipoxygenase, partial	1	0	0	1
ATAD5 protein, partial	3	0	0	3
NFKB1 protein, partial	1	0	0	1
TDP1 protein	13	0	0	13
Thrombopoietin	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	6	0	0	6
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
thyroid stimulating hormone receptor	3	0	0	3
regulator of G-protein signaling 4	3	0	0	3
EWS/FLI fusion protein	5	0	0	5
67.9K protein	4	0	0	4
Parkin	3	0	0	3
euchromatic histone-lysine N-methyltransferase 2	5	0	0	5
cytochrome P450 2D6 isoform 1	2	0	0	2
cellular tumor antigen p53 isoform a	2	0	0	2
cytochrome P450 2C19 precursor	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
chromobox protein homolog 1	8	0	0	8
flap endonuclease 1	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
survival motor neuron protein isoform d	4	0	0	4
cytochrome P450 3A4 isoform 1	4	0	0	4
M-phase phosphoprotein 8	2	0	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	1	1	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	4	0	0	4
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Bromodomain-containing protein 4	0	1	0	1
5-hydroxytryptamine receptor 4	0	4	0	4
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Integrin beta-3	2	0	0	2
Cytochrome P450 1A2	0	1	0	1
Integrin alpha-IIb	2	0	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
Serine/threonine-protein kinase pim-1	0	1	1	2
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit delta	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-2	4	0	0	4
Casein kinase II subunit alpha'	0	1	1	2
Gamma-aminobutyric acid receptor subunit alpha-5	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-2	4	0	0	4
Proteinase-activated receptor 1	0	0	0	1
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	2
5-hydroxytryptamine receptor 2A	0	4	0	4
5-hydroxytryptamine receptor 2C	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-4	4	0	0	4
Gamma-aminobutyric acid receptor subunit gamma-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit alpha-6	4	0	0	4
Sodium-dependent serotonin transporter	0	2	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	2	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	0	3
Serine/threonine-protein kinase mTOR	0	1	0	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	2	0	0	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	0	2
Glycogen synthase kinase-3 beta	0	1	1	2
D(1A) dopamine receptor	2	0	0	2
Serine/threonine-protein kinase PLK1	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-1	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-3	4	0	0	4
Gamma-aminobutyric acid receptor subunit beta-2	4	0	0	4
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha	0	1	0	1
DNA-dependent protein kinase catalytic subunit	0	2	0	2
Mu-type opioid receptor	0	1	0	1
Serine-protein kinase ATM	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
Serine/threonine-protein kinase ATR	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	1	0	1
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
GABA theta subunit	4	0	0	4
Gamma-aminobutyric acid receptor subunit epsilon	4	0	0	4
Serine/threonine-protein kinase PLK3	0	2	0	2
Serine/threonine-protein kinase PLK2	0	1	0	1
ATP-dependent phosphofructokinase	2	0	0	2
Luciferase	3	0	0	3
acetylcholinesterase	7	0	0	7
RAR-related orphan receptor gamma	13	0	0	13
GLI family zinc finger 3	12	0	0	12
AR protein	16	0	0	16
nuclear receptor subfamily 1, group I, member 3	8	0	0	8
retinoic acid nuclear receptor alpha variant 1	12	0	0	12
estrogen-related nuclear receptor alpha	12	0	0	12
pregnane X nuclear receptor	12	0	0	12
aryl hydrocarbon receptor	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	9	0	0	9
thyroid stimulating hormone receptor	8	0	0	8
Olfactory receptor 51E2	0	0	1	1
interleukin 8	6	0	0	6
SMAD family member 2	8	0	0	8
SMAD family member 3	8	0	0	8
Smad3	2	0	0	2
estrogen receptor 2 (ER beta)	6	0	0	6
progesterone receptor	10	0	0	10
cytochrome P450 family 3 subfamily A polypeptide 4	5	0	0	5
nonstructural protein 1	3	0	0	3
glucocorticoid receptor [Homo sapiens]	11	0	0	11
retinoid X nuclear receptor alpha	9	0	0	9
farnesoid X nuclear receptor	7	0	0	7
estrogen nuclear receptor alpha	14	0	0	14
peroxisome proliferator-activated receptor delta	9	0	0	9
peroxisome proliferator activated receptor gamma	11	0	0	11
vitamin D (1,25- dihydroxyvitamin D3) receptor	9	0	0	9
Histone H2A.x	7	0	0	7
Caspase-7	2	0	0	2
Bloom syndrome protein isoform 1	2	0	0	2
peripheral myelin protein 22 isoform 1	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
caspase-3	2	0	0	2
thyroid hormone receptor beta isoform 2	12	0	0	12
importin subunit beta-1 isoform 1	2	0	0	2
mitogen-activated protein kinase 1	2	0	0	2
nuclear factor NF-kappa-B p105 subunit isoform 1	1	0	0	1
snurportin-1	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 1	11	0	0	11
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA polymerase iota isoform a (long)	3	0	0	3
nuclear receptor ROR-gamma isoform 1	3	0	0	3
geminin	11	0	0	11
peripheral myelin protein 22	4	0	0	4
muscleblind-like protein 1 isoform 1	2	0	0	2
lamin isoform A-delta10	6	0	0	6
neuropeptide S receptor isoform A	2	0	0	2
Sex hormone-binding globulin	0	1	5	6
Beta-glucuronidase	0	1	0	1
Cholinesterase	0	1	0	1
Corticosteroid-binding globulin	0	3	0	3
Aromatase	0	4	0	7
Gastrin/cholecystokinin type B receptor	0	0	0	1
Testosterone 17-beta-dehydrogenase 3	0	3	0	3
Alpha-synuclein	2	1	0	3
Nuclear receptor ROR-gamma	5	0	0	5
TAR DNA-binding protein 43	1	0	0	1
Cellular tumor antigen p53	7	0	0	7
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	3	0	0	3
Chain A, Beta-lactamase	7	0	0	7
GALC protein	3	0	0	3
IDH1	4	0	0	4
thyrotropin-releasing hormone receptor	3	0	0	3
v-jun sarcoma virus 17 oncogene homolog (avian)	7	0	0	7
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	4	2	7
Muscarinic acetylcholine receptor M4	0	4	2	7
Muscarinic acetylcholine receptor M1	0	2	1	5
Muscarinic acetylcholine receptor M3	0	2	1	4
Muscarinic acetylcholine receptor M4	0	2	0	3
Muscarinic acetylcholine receptor M5	0	2	0	3
Muscarinic acetylcholine receptor M5	0	4	2	7
Muscarinic acetylcholine receptor M2	0	2	0	3
Muscarinic acetylcholine receptor M1	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	1	2
Muscarinic acetylcholine receptor M3	0	4	2	7
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Delta-type opioid receptor	0	0	0	1
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	0	1	1
Muscarinic acetylcholine receptor	0	3	0	3
Muscarinic acetylcholine receptor M3	0	0	1	3
Muscarinic acetylcholine receptor M2	0	0	0	3
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
hypoxia-inducible factor 1 alpha subunit	5	0	0	5
cytochrome P450 2D6	3	0	0	3
activating transcription factor 6	4	0	0	4
ATP-binding cassette sub-family C member 3	0	7	0	7
Multidrug resistance-associated protein 4	0	7	0	7
Bile salt export pump	0	7	0	7
Matrix metalloproteinase-9	0	1	0	1
Inositol monophosphatase 1	1	0	0	1
Isocitrate lyase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	8	0	9
Prothrombin	0	1	0	1
Glandular kallikrein	0	1	0	1
Cell division protein FtsZ	0	0	1	2
Chain A, Sex Hormone-Binding Globulin	0	0	1	1
glp-1 receptor, partial	3	0	0	3
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	7	0	0	7
vitamin D3 receptor isoform VDRA	3	0	0	3
transcriptional regulator ERG isoform 3	3	0	0	3
Voltage-dependent calcium channel gamma-2 subunit	8	0	0	8
Plasma kallikrein	0	1	0	1
Glucocorticoid receptor	0	5	1	7
Progesterone receptor	0	1	0	1
Progesterone receptor	0	4	2	6
Glucocorticoid receptor	0	1	0	1
Mineralocorticoid receptor	0	2	0	2
Sex hormone-binding globulin	0	1	0	1
Androgen receptor	0	4	4	10
Glutamate receptor 2	8	0	0	8
Mineralocorticoid receptor	0	1	0	1
Angiotensin-converting enzyme	0	0	1	1
Cannabinoid receptor 2	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	2	2
Neuropeptide FF receptor 2	0	0	0	1
ALK tyrosine kinase receptor	0	1	0	1
PPM1D protein	4	0	0	4
nuclear receptor subfamily 1, group I, member 2	3	0	0	3
Interferon beta	9	0	0	9
ATPase family AAA domain-containing protein 5	5	0	0	5
Ataxin-2	5	0	0	5
Genome polyprotein	0	1	0	1
Fumarate hydratase	3	0	0	3
polyprotein	3	0	0	3
Tyrosine-protein kinase Fyn	0	2	1	3
UDP-glucuronosyltransferase 2B7	0	0	0	1
Spike glycoprotein	5	0	1	6
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
Chain H, IGG1-KAPPA DB3 FAB (HEAVY CHAIN)	0	1	0	1
Chain L, IGG1-KAPPA DB3 FAB (LIGHT CHAIN)	0	1	0	1
ClpP	1	0	0	1
Guanine nucleotide-binding protein G	2	0	0	2
caspase 7, apoptosis-related cysteine protease	2	0	0	2
caspase-3	2	0	0	2
LMP1 [Human herpesvirus 4]	0	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 2	3	0	0	3
heat shock protein beta-1	3	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
urokinase-type plasminogen activator precursor	2	0	0	2
plasminogen precursor	2	0	0	2
urokinase plasminogen activator surface receptor precursor	2	0	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Prothrombin	0	0	0	1
Regulatory protein E2	0	0	1	1
ATP-dependent translocase ABCB1	0	1	0	1
ATP-dependent translocase ABCB1	0	4	1	6
Cytochrome P450 3A4	0	2	0	2
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 2-alpha	0	1	2	8
Cytochrome P450 2C9	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
DNA topoisomerase 2	0	0	0	1
ATP-dependent translocase ABCB1	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Caspase-3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
DNA topoisomerase 2-alpha	0	0	0	1
DNA topoisomerase 2-beta	0	1	2	9
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Tubulin beta-2B chain	0	1	0	1
Integrase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
G	5	0	0	5
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	0	1	0	1
Cytochrome P450 2C19	0	2	0	2
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase	0	1	0	1
Inositol hexakisphosphate kinase 1	5	0	0	5
cytochrome P450 2C9, partial	5	0	0	5
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
endonuclease IV	1	0	0	1
Skn7p	0	0	0	1
pregnane X receptor	2	0	0	2
Microtubule-associated protein tau	3	0	0	3
arylsulfatase A	2	0	0	2
hemoglobin subunit beta	1	0	0	1
huntingtin isoform 2	1	0	0	1
Vpr	1	0	0	1
Solute carrier family 22 member 8	0	0	0	1
Epidermal growth factor receptor	0	2	1	3
Amyloid-beta precursor protein	1	0	0	1
Thymidylate synthase	0	1	0	1
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
USP1 protein, partial	2	0	0	2
thioredoxin glutathione reductase	1	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	1	0	0	1
lethal factor (plasmid)	2	0	0	2
Sulfotransferase 1A1	0	0	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	1	1	2
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Tyrosine-protein kinase ABL1	0	0	1	1
Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	1	1	2
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Lck	0	1	1	2
Cyclin-dependent kinase 1	0	0	1	1
Glycogen phosphorylase, liver form	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	0	1	1
Tyrosine-protein kinase Lyn	0	0	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	0	2	1	3
Insulin-like growth factor 1 receptor	0	0	1	1
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Hepatocyte growth factor receptor	0	0	1	1
Tyrosine-protein kinase HCK	0	0	1	1
Platelet-derived growth factor receptor beta	0	1	1	2
Serine/threonine-protein kinase A-Raf	0	0	1	1
Glycogen phosphorylase, brain form	0	0	1	1
Breakpoint cluster region protein	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
Cyclin-dependent kinase 4	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Serine/threonine-protein kinase B-raf	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	0	1
Tyrosine-protein kinase Fer	0	0	1	1
Protein kinase C alpha type	0	1	1	2
cAMP-dependent protein kinase catalytic subunit alpha	0	0	1	1
Vascular endothelial growth factor receptor 1	0	1	0	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Cyclin-dependent kinase 2	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Mitogen-activated protein kinase 3	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Mitogen-activated protein kinase 1	0	0	1	1
Ephrin type-A receptor 2	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
RAC-alpha serine/threonine-protein kinase	0	0	1	1
RAC-beta serine/threonine-protein kinase	0	0	1	1
Kinesin-1 heavy chain	0	1	0	1
DNA replication licensing factor MCM4	0	0	1	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Myosin-10	0	0	1	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Receptor-type tyrosine-protein kinase FLT3	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	1	1	2
Exosome RNA helicase MTR4	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase ABL2	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase SYK	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
MAP kinase-activated protein kinase 2	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Glycogen synthase kinase-3 alpha	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
Serine/threonine-protein kinase Nek2	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 10	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-1	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Cyclin-dependent kinase 6	0	0	1	1
Cyclin-dependent-like kinase 5	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 1	0	0	1	1
Protein kinase C theta type	0	1	1	2
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Focal adhesion kinase 1	0	0	1	1
Protein kinase C delta type	0	1	1	2
Tyrosine-protein kinase BTK	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	1	1
Activin receptor type-2B	0	0	1	1
Nuclear receptor coactivator 4	0	1	0	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Coiled-coil domain-containing protein 6	0	1	0	1
Serine/threonine-protein kinase N1	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Mitogen-activated protein kinase 14	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Discoidin domain-containing receptor 2	0	0	1	1
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Rab-like protein 3	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
ATP-dependent RNA helicase DDX42	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
MAP kinase-activated protein kinase 5	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Aurora kinase B	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Serine/threonine-protein kinase Nek1	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
PINK1	2	0	0	2
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	1	0	0	1
Glycine receptor subunit alpha-1	0	4	0	4
Glycine receptor subunit beta	0	4	0	4
Glycine receptor subunit alpha-2	0	4	0	4
Glycine receptor subunit alpha-3	0	4	0	4
Estrogen receptor	0	3	2	6
Histamine H2 receptor	0	4	0	4
5-hydroxytryptamine receptor 1B	0	3	0	3
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Aldo-keto reductase family 1 member C1	0	1	0	1
Estrogen receptor beta	0	3	2	5
Chain A, CES1 protein	0	1	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	1	0	0	1
Chain A, Ferritin light chain	1	0	0	1
phosphopantetheinyl transferase	1	0	0	1
apical membrane antigen 1, AMA1	1	0	0	1
DNA polymerase III, partial	1	0	0	1
glucocerebrosidase	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
interferon gamma precursor	0	0	0	1
D(1A) dopamine receptor	1	0	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
ras-related protein Rab-9A	1	0	0	1
streptokinase A precursor	0	0	1	1
Transmembrane protease serine 2	0	0	1	1
Lysosomal acid glucosylceramidase	0	0	1	1
Receptor tyrosine-protein kinase erbB-2	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	2
Procathepsin L	0	0	1	1
Aldo-keto reductase family 1 member B1	0	2	0	2
Beta-1 adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Adenosine receptor A3	0	2	0	2
Replicase polyprotein 1ab	0	0	1	1
Steroid hormone receptor ERR1	0	1	0	1
Transcriptional activator protein LuxR	0	1	0	1
Angiotensin-converting enzyme	0	2	0	2
Beta-3 adrenergic receptor	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Alpha-1B adrenergic receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	2
Cytochrome P450 2B6	0	1	0	1
Substance-K receptor	0	2	0	2
D(1A) dopamine receptor	0	2	0	2
D(4) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium-dependent noradrenaline transporter	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Protein kinase C eta type	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Substance-P receptor	0	2	0	2
Adenosine receptor A2a	0	2	0	2
B2 bradykinin receptor	0	2	0	2
Adenosine receptor A1	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
Melanocortin receptor 4	0	2	0	2
C-8 sterol isomerase	0	1	0	1
Melanocortin receptor 5	0	2	0	2
Mu-type opioid receptor	0	2	0	2
D(3) dopamine receptor	0	2	0	2
Delta-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Melanocortin receptor 3	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Estrogen-related receptor gamma	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Phospholipase D1	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	2	0	2
Platelet-activating factor acetylhydrolase	0	1	0	1
Phospholipase D1	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	1	3
Serine/threonine-protein kinase D1	0	1	0	1
Estrogen receptor beta	0	0	1	2
Protein kinase C eta type	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Sigma non-opioid intracellular receptor 1	0	2	0	2
Emopamil-binding protein-like	0	1	0	1
Angiotensin-converting enzyme 2	0	0	1	1
7-dehydrocholesterol reductase	0	1	1	2
Protein kinase C theta type	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (41)

Protein Targets (702)

Adenosarcoma

Synonyms(1)

Research Excerpts

Overview

Context

Research

Studies (41)

Drugs Studied (34)

Protein Targets (702)