Page last updated: 2024-09-28

Pederasty

A sexual disorder occurring in a person 16 years or older and that is recurrent with intense sexually arousing fantasies, sexual urges, or behaviors involving sexual activity with a prepubescent child (generally age 13 or younger). (from APA, DSM-IV, 1994).

Synonyms(2)

Synonym
Pederasty
Pedophilia

Research Excerpts

Overview

ExcerptReference
"Pedophilia is characterized by a persistent sexual attraction to prepubescent children."( Dittmann, V; Graf, M; Habermeyer, B; Händel, N; Klarhöfer, M; Lemoine, P; Seifritz, E, 2012)

Treatment

ExcerptReference
"Three chronic pedophiliac sex offenders were treated individually with medroxyprogesterone acetate (MPA) over a minimum of 3 months."( Bansal, S; Malamud, M; Wincze, JP, 1986)
"A hypersexual pedophiliac sex offender was treated with the antiandrogen medroxyprogesterone acetate for 500 days."( Chapel, JL; Cordoba, OA, 1983)
"An individual with pedophilia and trichotillomania was treated with sertraline."( Bradford, JM; Gratzer, TG, 1995)

Research

Studies (85)

TimeframeStudies, This Condition (%)All Conditions %
pre-199021 (24.71)23.3326
1990's24 (28.24)12.5806
2000's20 (23.53)18.1394
2010's17 (20.00)28.8240
2020's3 (3.53)9.53
DrugIndicatedRelationship StrengthStudiesTrials
1-(3-chlorophenyl)piperazine0low20
3,4-methylenedioxyamphetamine0low50
benserazide0low10
carbamazepine0low10
clonazepam0low10
valproic acid0low10
fluoxetine0low20
mianserin0medium11
risperidone0low10
ropinirole0low10
levodopa0low20
medroxyprogesterone acetate0medium131
1-naphthylamine0low20
cyproterone acetate0medium163
medroxyprogesterone0medium101
lithium carbonate0low10
s,n,n'-tripropylthiocarbamate0low10
bromocriptine0low20
4-methoxyamphetamine0low10
pergolide0low10
buserelin0low20
fomesafen0low10
fluorodeoxyglucose f180low10
sertraline0low20
leuprolide0medium113
lithium0low20
freedom0low10
cyproterone0low60
goserelin0low20
acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ilys-prolyl-alaninamide0medium21
sodium ethylxanthate0low20
quetiapine fumarate0low10
trelstar0medium41
sildenafil citrate0low10
ego0low10

Protein Targets (435)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, TYROSYL-DNA PHOSPHODIESTERASE3003
5-hydroxytryptamine receptor 3E0202
acetylcholinesterase4004
TDP1 protein110011
cytochrome P450 2D65005
v-jun sarcoma virus 17 oncogene homolog (avian)7007
cytochrome P450 2D6 isoform 13003
cellular tumor antigen p53 isoform a1001
cytochrome P450 2C19 precursor3003
cytochrome P450 2C9 precursor2002
thyroid hormone receptor beta isoform a4004
thyroid hormone receptor beta isoform 29009
huntingtin isoform 23003
peripheral myelin protein 226006
cytochrome P450 3A4 isoform 16006
muscarinic acetylcholine receptor M14004
Gamma-aminobutyric acid receptor subunit pi6107
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
ATP-binding cassette sub-family C member 30707
Multidrug resistance-associated protein 40707
5-hydroxytryptamine receptor 3B0202
Bile salt export pump011011
Beta-1 adrenergic receptor0303
5-hydroxytryptamine receptor 1A07411
5-hydroxytryptamine receptor 2C010212
D(2) dopamine receptor010313
5-hydroxytryptamine receptor 2A010212
Gamma-aminobutyric acid receptor subunit beta-16107
Alpha-1B adrenergic receptor0617
Gamma-aminobutyric acid receptor subunit delta6107
Gamma-aminobutyric acid receptor subunit gamma-26107
D0606
5-hydroxytryptamine receptor 1A010212
Gamma-aminobutyric acid receptor subunit alpha-56107
Gamma-aminobutyric acid receptor subunit alpha-36107
Gamma-aminobutyric acid receptor subunit gamma-16107
Gamma-aminobutyric acid receptor subunit alpha-26107
Alpha-1D adrenergic receptor0617
5-hydroxytryptamine receptor 2A013417
5-hydroxytryptamine receptor 2C013316
Gamma-aminobutyric acid receptor subunit alpha-46107
Gamma-aminobutyric acid receptor subunit gamma-36107
5-hydroxytryptamine receptor 1B011213
5-hydroxytryptamine receptor 1D0527
Gamma-aminobutyric acid receptor subunit alpha-66107
5-hydroxytryptamine receptor 1F0527
5-hydroxytryptamine receptor 5A0101
5-hydroxytryptamine receptor 2B010212
Sodium-dependent serotonin transporter010515
5-hydroxytryptamine receptor 7 0527
5-hydroxytryptamine receptor 70404
Alpha-1B adrenergic receptor0202
Glutamate receptor ionotropic, NMDA 1 0102
5-hydroxytryptamine receptor 2B011112
Alpha-1A adrenergic receptor0617
5-hydroxytryptamine receptor 3A0202
Histamine H2 receptor2104
5-hydroxytryptamine receptor 6010011
Beta-2 adrenergic receptor0101
D(2) dopamine receptor011213
Gamma-aminobutyric acid receptor subunit alpha-16107
Gamma-aminobutyric acid receptor subunit beta-36107
Gamma-aminobutyric acid receptor subunit beta-26107
Glutamate receptor ionotropic, NMDA 2A 0102
Glutamate receptor ionotropic, NMDA 2B0102
Glutamate receptor ionotropic, NMDA 2C0102
Glutamate receptor ionotropic, NMDA 2D0102
5-hydroxytryptamine receptor 3D0202
Glutamate receptor ionotropic, NMDA 3B0102
5-hydroxytryptamine receptor 3C0202
GABA theta subunit6107
Canalicular multispecific organic anion transporter 10707
Gamma-aminobutyric acid receptor subunit epsilon6107
Glutamate receptor ionotropic, NMDA 3A0102
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
RAR-related orphan receptor gamma7007
GLI family zinc finger 38008
AR protein130013
aldehyde dehydrogenase 1 family, member A14004
thyroid stimulating hormone receptor4004
estrogen receptor 2 (ER beta)5005
nuclear receptor subfamily 1, group I, member 39009
progesterone receptor9009
glucocorticoid receptor [Homo sapiens]120012
retinoic acid nuclear receptor alpha variant 19009
estrogen-related nuclear receptor alpha130013
pregnane X nuclear receptor110011
estrogen nuclear receptor alpha160016
aryl hydrocarbon receptor2002
thyroid stimulating hormone receptor4004
activating transcription factor 62002
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a5005
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
nuclear factor erythroid 2-related factor 2 isoform 19009
Voltage-dependent calcium channel gamma-2 subunit4004
Glutamate receptor 24004
Kelch-like ECH-associated protein 10011
Histone acetyltransferase KAT80101
Sodium-dependent noradrenaline transporter 08210
Sodium-dependent dopamine transporter0415
5-hydroxytryptamine receptor 60224
Sodium-dependent serotonin transporter0617
5-hydroxytryptamine receptor 5A0224
5-hydroxytryptamine receptor 5B0224
5-hydroxytryptamine receptor 3A0325
Sodium-dependent dopamine transporter 0628
5-hydroxytryptamine receptor 4 0224
5-hydroxytryptamine receptor 3B0325
Gonadotropin-releasing hormone receptor0213
thioredoxin reductase6006
GLS protein6006
regulator of G-protein signaling 46006
EWS/FLI fusion protein4004
arylsulfatase A4004
euchromatic histone-lysine N-methyltransferase 2100010
vitamin D3 receptor isoform VDRA5005
chromobox protein homolog 19009
serine/threonine-protein kinase mTOR isoform 14004
M-phase phosphoprotein 82002
Zinc finger protein mex-50011
POsterior Segregation0011
Genome polyprotein0101
Replicase polyprotein 1ab0101
D(1A) dopamine receptor3003
Hexokinase-20101
ATP-dependent phosphofructokinase5005
Genome polyprotein 0112
dopamine D1 receptor3003
ATAD5 protein, partial5005
Fumarate hydratase3003
cytochrome P450 family 3 subfamily A polypeptide 46006
G6006
polyprotein3003
peroxisome proliferator activated receptor gamma8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a9009
D(1A) dopamine receptor6006
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
5-hydroxytryptamine receptor 4012012
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 6006
Cellular tumor antigen p537007
ATP-dependent translocase ABCB10101
ATP-dependent translocase ABCB10304
Cytochrome P450 3A40404
Alpha-2A adrenergic receptor011011
Androgen receptor0808
Alpha-2B adrenergic receptor012012
Alpha-2C adrenergic receptor010010
D(3) dopamine receptor0606
Alpha-2B adrenergic receptor0617
ATP-dependent translocase ABCB10101
D(1A) dopamine receptor0819
Alpha-2C adrenergic receptor0617
Alpha-2A adrenergic receptor0617
Alpha-1D adrenergic receptor0808
D(1B) dopamine receptor0303
D(4) dopamine receptor0303
D(3) dopamine receptor09110
Alpha-synuclein1203
Inositol hexakisphosphate kinase 16006
ATPase family AAA domain-containing protein 53003
Ataxin-26006
cytochrome P450 2C9, partial6006
Chain A, Beta-lactamase5005
USP1 protein, partial3003
IDH13003
nuclear factor erythroid 2-related factor 2 isoform 23003
mitogen-activated protein kinase 12002
geminin8008
Vpr1001
lamin isoform A-delta107007
Bile salt export pump0202
Albumin0033
Major prion protein0011
Sodium channel protein type 1 subunit alpha0202
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Cytochrome P450 2C9 0303
UDP-glucuronosyltransferase 2B70103
Cytochrome P450 2B60011
Sodium channel protein type 4 subunit alpha0102
Cytochrome P450 2J20303
Potassium voltage-gated channel subfamily H member 20808
Sodium channel protein type 9 subunit alpha0202
Frizzled-80011
P2X purinoceptor 40101
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-10101
Neuronal acetylcholine receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Neuronal acetylcholine receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-10303
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit gamma-20303
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30303
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50303
Gamma-aminobutyric acid receptor subunit alpha-30303
Gamma-aminobutyric acid receptor subunit alpha-20303
Gamma-aminobutyric acid receptor subunit beta-20303
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit epsilon0303
Gamma-aminobutyric acid receptor subunit alpha-60303
Gamma-aminobutyric acid receptor subunit gamma-10303
Gamma-aminobutyric acid receptor subunit gamma-30303
Gamma-aminobutyric acid receptor subunit theta0303
nuclear receptor subfamily 1, group I, member 24004
Chain A, Cruzipain2002
pregnane X receptor3003
SMAD family member 23003
SMAD family member 33003
Smad33003
retinoid X nuclear receptor alpha4004
farnesoid X nuclear receptor4004
67.9K protein2002
peroxisome proliferator-activated receptor delta4004
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
heat shock protein beta-12002
nuclear receptor ROR-gamma isoform 11001
Glucocorticoid receptor0617
Progesterone receptor0314
Glycine receptor subunit alpha-10606
Androgen receptor0426
Glycine receptor subunit beta0606
Glycine receptor subunit alpha-20606
Glycine receptor subunit alpha-30606
Adenosine receptor A10203
Adenosine receptor A2b0101
Adenosine receptor A2a0102
Mu-type opioid receptor0202
Nuclear receptor ROR-gamma3003
Spike glycoprotein6006
ORF730011
caspase 7, apoptosis-related cysteine protease1001
caspase-31001
Histone H2A.x3003
Caspase-72002
NPC intracellular cholesterol transporter 1 precursor2002
potassium voltage-gated channel subfamily H member 2 isoform d7007
caspase-32002
atrial natriuretic peptide receptor 2 precursor2002
ras-related protein Rab-9A3003
Sodium-dependent noradrenaline transporter0101
Potassium channel subfamily K member 20101
Aldo-keto reductase family 1 member B10707
Muscarinic acetylcholine receptor M50707
Cytochrome P450 2C80101
Cytochrome P450 2D60404
Muscarinic acetylcholine receptor M10707
Angiotensin-converting enzyme0606
Dipeptidyl peptidase 40101
Muscarinic acetylcholine receptor M30606
Acetylcholinesterase0101
Acetylcholinesterase0101
Prostaglandin G/H synthase 10101
Potassium voltage-gated channel subfamily C member 10101
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Cytochrome P450 2C190303
Gastrin/cholecystokinin type B receptor 0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4B0101
cAMP-specific 3',5'-cyclic phosphodiesterase 4D0101
Cytochrome P450 1B10101
Sigma intracellular receptor 20202
Sigma non-opioid intracellular receptor 10202
Sodium-dependent serotonin transporter0101
Sodium-dependent dopamine transporter0101
Transporter0202
Nuclear receptor subfamily 3 group C member 3 0606
Beta-2 adrenergic receptor0101
Sigma non-opioid intracellular receptor 10505
Sigma non-opioid intracellular receptor 10202
Transporter0505
Histamine H3 receptor0202
Luciferase4004
hypoxia-inducible factor 1 alpha subunit2002
Gonadotropin-releasing hormone receptor0202
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, 2-oxoglutarate Oxygenase2002
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
15-lipoxygenase, partial1001
WRN1001
integrase, partial0101
lens epithelium-derived growth factor p750101
phosphopantetheinyl transferase4004
apical membrane antigen 1, AMA11001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
pyruvate kinase1001
Bloom syndrome protein isoform 11001
hexokinase-4 isoform 11001
atrial natriuretic peptide receptor 1 precursor1001
glucokinase regulatory protein1001
importin subunit beta-1 isoform 11001
flap endonuclease 12002
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
snurportin-11001
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)2002
DNA polymerase kappa isoform 11001
Polyphenol oxidase 20001
Carbonic anhydrase 120002
Epidermal growth factor receptor0101
Carbonic anhydrase 10002
Carbonic anhydrase 20002
Plasma kallikrein0001
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Carbonic anhydrase 30002
Polyunsaturated fatty acid lipoxygenase ALOX150101
Tyrosinase0101
Carbonic anhydrase 40002
Carbonic anhydrase 60002
Carbonic anhydrase 5A, mitochondrial0002
Carbonic anhydrase0001
Carbonic anhydrase 70002
Solute carrier family 15 member 10101
Carbonic anhydrase0001
Large neutral amino acids transporter small subunit 10101
SLC16A10 protein0001
Carbonic anhydrase 90002
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Carbonic anhydrase 130002
Carbonic anhydrase 140002
Carbonic anhydrase 5B, mitochondrial0002
phosphoglycerate kinase1001
GALC protein1001
Microtubule-associated protein tau1001
PINK12002
Parkin2002
interleukin 81001
nonstructural protein 12002
transcriptional regulator ERG isoform 32002
neuropeptide S receptor isoform A1001
Estrogen receptor0112
Sex hormone-binding globulin0011
Mineralocorticoid receptor 0101
Androgen receptor0011
Histamine H2 receptor0606
Aldo-keto reductase family 1 member C30101
Aldo-keto reductase family 1 member C2 0101
Guanine nucleotide-binding protein G1001
Aldo-keto reductase family 1 member C10101
Estrogen receptor beta0112
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)2002
Muscarinic acetylcholine receptor M20505
Muscarinic acetylcholine receptor M40505
Muscarinic acetylcholine receptor M50101
Endothelin receptor type B0101
D(4) dopamine receptor0213
5-hydroxytryptamine receptor 3A0202
Endothelin receptor type B0101
Endothelin-1 receptor0101
5-hydroxytryptamine receptor 1D0101
Histamine H1 receptor0101
Alpha-1A adrenergic receptor0303
Type-2 angiotensin II receptor0202
Histamine H1 receptor0404
Angiotensin-converting enzyme0101
Inositol monophosphatase 11001
5-hydroxytryptamine receptor 3B0202
G-protein coupled receptor 0101
mu-type opioid receptor isoform MOR-10011
5-hydroxytryptamine receptor 2A0011
D(2) dopamine receptor0202
D0101
peripheral myelin protein 22 isoform 11001
survival motor neuron protein isoform d1001
Solute carrier family 22 member 20101
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Beta-1 adrenergic receptor0101
Glycine receptor subunit alpha-10011
Histamine H1 receptor0101
5-hydroxytryptamine receptor 2C 0101
5-hydroxytryptamine receptor 2A0101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
D(2) dopamine receptor0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
5-hydroxytryptamine receptor 2B0101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Sodium channel protein type 5 subunit alpha0101
5-hydroxytryptamine receptor 1A0101
Multidrug and toxin extrusion protein 20101
Multidrug and toxin extrusion protein 10101
D(1B) dopamine receptor0011
glp-1 receptor, partial1001
PPM1D protein1001
histone-lysine N-methyltransferase 2A isoform 2 precursor1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Rap guanine nucleotide exchange factor 31001
Transcriptional activator protein LuxR0101
3-oxo-5-alpha-steroid 4-dehydrogenase 20101
Melanocortin receptor 50202
Envelope glycoprotein0011
cGMP-specific 3',5'-cyclic phosphodiesterase0101
Cocaine esterase0101
Histone deacetylase 30202
UDP-glucuronosyltransferase 1A90001
Cytochrome P450 2A60101
Tissue factor0101
Aldo-keto reductase family 1 member A10101
UDP-glucuronosyltransferase 1-60001
Liver carboxylesterase 10101
Aldo-keto reductase family 1 member A10101
Histone deacetylase 40202
Histone deacetylase 10202
Aldo-keto reductase family 1 member A10101
Aldo-keto reductase family 1 member B70101
Histone deacetylase 70202
Histone deacetylase 20202
Polyamine deacetylase HDAC100202
Histone deacetylase 11 0202
Histone deacetylase 80202
NAD-dependent protein deacylase sirtuin-5, mitochondrial0101
Histone deacetylase 60202
Histone deacetylase 90202
Histone deacetylase 50202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]