| Assay ID | Title | Year | Journal | Article |
|---|
| AID1166880 | Inhibition of human BBOX pre-incubated for 1 min using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1374901 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS assessed as zinc ions ejection from Cys4-Zn finger at 100 uM by FluoZin-3 based fluorescence assay | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1166892 | Binding affinity to human BBOX in presence of Fe(II) by tryptophan fluorescence quenching binding assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1166882 | Inhibition of human BBOX pre-incubated for 15 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1374896 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 100 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addit | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1374902 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS assessed as zinc ions ejection from Cys4-Zn finger at 100 uM by FluoZin-3 based fluorescence assay | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1374898 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 100 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addit | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1166885 | Induction of Zn(II) from human BBOX assessed as zinc release by fluorescence based assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1374899 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addition measur | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1166883 | Inhibition of human BBOX pre-incubated for 20 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1166884 | Inhibition of human BBOX pre-incubated for 25 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1374897 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 10 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM additi | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1374895 | Inhibition of wild type recombinant human histone lysine methyltransferase G9a (913 to 1193 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS at 10 uM using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM additi | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1474294 | Inhibition of recombinant human membrane bound carbonic anhydrase 4 pretreated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry, 04-15, Volume: 25, Issue:8
| Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. |
| AID1166887 | Binding affinity to human BBOX assessed as quenching of intrinsic tryptophan fluorescence at 50 to 200 uM in absence of Fe(II) | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1474296 | Inhibition of recombinant human transmembrane carbonic anhydrase 9 pretreated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry, 04-15, Volume: 25, Issue:8
| Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. |
| AID1374900 | Inhibition of wild type recombinant human histone lysine methyltransferase GLP (951 to 1235 residues) expressed in Escherichia coli Rosetta BL21 DE3 PlysS using ARTKQTARKSTGGKA as substrate preincubated for 5 mins followed by substrate/SAM addition measur | 2018 | Bioorganic & medicinal chemistry letters, 04-15, Volume: 28, Issue:7
| Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II). |
| AID1474295 | Inhibition of recombinant human cytosolic carbonic anhydrase 7 pretreated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry, 04-15, Volume: 25, Issue:8
| Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. |
| AID1474293 | Inhibition of recombinant human cytosolic carbonic anhydrase 2 pretreated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry, 04-15, Volume: 25, Issue:8
| Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. |
| AID1166881 | Inhibition of human BBOX pre-incubated for 10 mins using TBS-protected fluorescein probe and Fe (II) (Fe(NH4)2(SO4)2 salt by fluoride release assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1166886 | Binding affinity to human BBOX assessed as quenching of intrinsic tryptophan fluorescence at 50 to 200 uM in presence of Fe(II) | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID1474292 | Inhibition of recombinant human cytosolic carbonic anhydrase 1 pretreated for 15 mins prior to testing measured for 10 to 100 secs by phenol red based stopped-flow CO2 hydration assay | 2017 | Bioorganic & medicinal chemistry, 04-15, Volume: 25, Issue:8
| Evaluation of selenide, diselenide and selenoheterocycle derivatives as carbonic anhydrase I, II, IV, VII and IX inhibitors. |
| AID1166891 | Binding affinity to human BBOX by tryptophan fluorescence quenching binding assay | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| AID100656 | In vitro growth inhibition against L1210 murine leukemia cells | 1990 | Journal of medicinal chemistry, Jun, Volume: 33, Issue:6
| Phenyl selenones: alkyl transfer by selenium-carbon bond cleavage. |
| AID1166888 | Binding affinity to human BBOX assessed as covalent modification by measuring PhSe group mass shift at 1 equivalent dose by LC-MS method | 2014 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 24, Issue:21
| Ejection of structural zinc leads to inhibition of γ-butyrobetaine hydroxylase. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |