sodium-pertechnetate-tc-99m and Thyroglossal-Cyst

Topics: Adult; Humans; Male; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Thyroglossal Cyst; Thyroid Dysgenesis; Thyroid Gland; Tomography, X-Ray Computed

Topics: Adolescent; Choristoma; Diagnosis, Differential; Humans; Male; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Thyroglossal Cyst; Thyroid Function Tests; Thyroid Gland; Tomography, Emission-Computed, Single-Photon

The exact prevalence and clinical significance of ectopic thyroid or thyroglossal duct remnant (TGDR) in the general population have not yet been fully determined despite numerous case reports. This study was prepared to assess the prevalence of TGDR in asymptomatic subjects during hypothyroidism after a total thyroidectomy for differentiated thyroid cancer (DTC) and to clarify the clinical implication.. Tc-99m pertechnetate scintigraphy (Tc-scan) of the head and neck before radioiodine ablation therapy and whole-body and pinhole I-131 scintigraphy (I-scan) after ablation therapy were reviewed for 131 consecutive DTC patients with hypothyroidism after a total thyroidectomy.. Forty-four among the 131 patients (33.6%) revealed an unexpected linear or focal radioactivity at the anterior midline of the neck, suggesting the presence of TGDR. The Tc-scan and pinhole I-scan were concordant in all cases of abnormal midline neck uptake, although the planar I-scan failed to delineate TGDR due to prominent photon scattering in most cases. Preoperative enhanced neck computed tomography scan was performed in 49 patients and showed no evidence of thyroid glandular tissue separated from thyroid gland in midline of the anterior neck except 1 case. The success rate after radioiodine ablation did not differ significantly between the positive and negative TGDR patients.. TGDR can be frequently observed in scintigraphy of hypothyroid subjects after a thyroidectomy, even when clinically unexpected. Therefore, care should be taken not to confuse the tracer uptake by TGDR with metastatic foci in I- and Tc-scans of patients with hypothyroidism after a thyroidectomy for DTC.

Topics: Adult; Aged; Choristoma; Combined Modality Therapy; Female; Humans; Hypothyroidism; Korea; Lymphatic Metastasis; Male; Middle Aged; Prevalence; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Thyroglobulin; Thyroglossal Cyst; Thyroid Gland; Thyroid Neoplasms; Thyroidectomy; Thyrotropin

The inadvertent removal of ectopic thyroid gland (ETG) that was mistaken for a thyroglossal duct cyst (TDC) leading to important hypothyroidism has been reported in the literature. The authors report the case of a 4-year-old boy with an ETG mimicking a normal TDC, in whom the preliminary diagnosis was a TDC. The diagnosis, the anatomic location of the ETG, and the management of this congenital anomaly are discussed.

Topics: Child, Preschool; Humans; Male; Radionuclide Imaging; Radiopharmaceuticals; Sodium Pertechnetate Tc 99m; Thyroglossal Cyst; Thyroid Gland

The clinical evaluation of thyroid imaging with 99mTc, 201Tl, and 67Ga in the uncommon, but potentially serious, disorder of acute suppurative thyroiditis (AST) with abscess formation due to infection from a persistent thyroglossal duct is reported. The 99mTc image showed functioning areas of the diseased thyroid gland and the 201Tl image demonstrated abscess formation in the thyroid gland of this patient. In addition, marked 67Ga accumulation was demonstrated in a wide area covering not only the area of the thyroid gland involved, but also associated circumferential inflammatory lesions in a patient with AST. The net thyroid uptake of 67Ga at 72 hours was calculated to be 13.8% of the injected dose.

Topics: Abscess; Adult; Gallium Radioisotopes; Humans; Male; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Streptococcal Infections; Thallium Radioisotopes; Thyroglossal Cyst; Thyroid Gland; Thyroiditis, Suppurative

Topics: Aged; Humans; Iodine Radioisotopes; Male; Radionuclide Imaging; Sodium Pertechnetate Tc 99m; Technetium; Thyroglossal Cyst; Ultrasonography