Page last updated: 2024-09-27

Anal Gland Neoplasms

Tumors or cancer of the anal gland.

Synonyms(6)

Synonym
Neoplasms, Perianal Gland
Neoplasms, Circumanal Gland
Perianal Gland Neoplasms
Neoplasms, Anal Gland
Anal Gland Neoplasms
Circumanal Gland Neoplasms

Research

Studies (44)

TimeframeStudies, This Condition (%)All Conditions %
pre-199027 (61.36)23.3326
1990's5 (11.36)12.5806
2000's0 (0.00)18.1394
2010's9 (20.45)28.8240
2020's3 (6.82)9.53
DrugIndicatedRelationship StrengthStudiesTrials
dinitrochlorobenzene0low10
pteridines0low10
1,2-dimethylhydrazine0low20
busulfan0low10
carmofur0low10
diazepam0low10
flumazenil0low10
fluorouracil0low40
mitotane0low10
tegafur0low10
hydroxyproline0low10
estrone0low10
pyrroles0low30
thiazoles0low10
d-alpha tocopherol0low10
androstane-3,17-diol0low10
dimethylhydrazines0low50
delphinidin0low10
carboplatin0low20
prostaglandin d20low10
bromochloroacetic acid0low30
calcitriol0low20
13,14-dihydro-15-ketoprostaglandin d20low10
methylazoxymethanol acetate0low10
phosphorus0low20
er-0865260low10
toceranib phosphate0low30
pardaxin0low10
mobic0low10
cyclosporine0low10
concanavalin a0low10

Protein Targets (436)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
RAR-related orphan receptor gamma110011
AR protein110011
aldehyde dehydrogenase 1 family, member A17007
nuclear receptor subfamily 1, group I, member 3110011
retinoic acid nuclear receptor alpha variant 1110011
thyroid stimulating hormone receptor4004
nuclear factor erythroid 2-related factor 2 isoform 1110011
Cellular tumor antigen p539009
Nuclear receptor ROR-gamma3003
Chain A, JmjC domain-containing histone demethylation protein 3A5005
Chain A, 2-oxoglutarate Oxygenase2002
15-lipoxygenase, partial2002
TDP1 protein110011
apical membrane antigen 1, AMA13003
thyroid stimulating hormone receptor4004
cytochrome P450 family 3 subfamily A polypeptide 48008
EWS/FLI fusion protein6006
glucocorticoid receptor [Homo sapiens]100010
retinoid X nuclear receptor alpha8008
estrogen-related nuclear receptor alpha100010
pregnane X nuclear receptor100010
estrogen nuclear receptor alpha120012
aryl hydrocarbon receptor5005
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a7007
thyroid hormone receptor beta isoform 29009
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
geminin100010
lethal factor (plasmid)3003
lamin isoform A-delta108008
ATP-binding cassette sub-family C member 30808
Multidrug resistance-associated protein 40808
Bile salt export pump010010
Matrix metalloproteinase-90101
Disintegrin and metalloproteinase domain-containing protein 171001
Canalicular multispecific organic anion transporter 10606
Chain A, Vitamin D Nuclear Receptor0011
Chain A, Beta-lactamase5005
Chain A, Ferritin light chain3003
Vitamin D3 receptor0011
USP1 protein, partial4004
PPM1D protein3003
Microtubule-associated protein tau7007
thioredoxin glutathione reductase2002
euchromatic histone-lysine N-methyltransferase 27007
mitogen-activated protein kinase 12002
nuclear receptor ROR-gamma isoform 15005
peripheral myelin protein 225005
Interferon beta100010
Vitamin D-binding protein0011
Cytochrome P450 1A20001
Cytochrome P450 3A40304
Androgen receptor0101
Cytochrome P450 2D60202
Vitamin D3 receptor0124
Cytochrome P450 2C9 0203
Vitamin D3 receptor0113
Retinoic acid receptor RXR-alpha0011
Cytochrome P450 2C190101
Kappa-type opioid receptor0011
Vitamin D3 receptor0011
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial0011
Vitamin D3 receptor0112
Transporter0101
Vitamin D3 receptor A0022
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE4004
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, Putative fructose-1,6-bisphosphate aldolase2002
acetylcholinesterase4004
phosphopantetheinyl transferase3003
estrogen receptor 2 (ER beta)100010
G7007
cytochrome P450 2D62002
vitamin D3 receptor isoform VDRA3003
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
DNA polymerase kappa isoform 11001
histone acetyltransferase KAT2A isoform 12002
HLA class I histocompatibility antigen, B alpha chain 7007
Inositol hexakisphosphate kinase 17007
cytochrome P450 2C9, partial7007
ATP-dependent phosphofructokinase3003
GLI family zinc finger 39009
farnesoid X nuclear receptor8008
67.9K protein4004
peroxisome proliferator activated receptor gamma9009
Histone H2A.x7007
Spike glycoprotein0112
Replicase polyprotein 1ab0112
potassium voltage-gated channel subfamily H member 2 isoform d3003
survival motor neuron protein isoform d4004
cytochrome P450 3A4 isoform 15005
Gamma-aminobutyric acid receptor subunit pi54110
Transmembrane protease serine 20112
Procathepsin L0112
Replicase polyprotein 1a0112
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Gamma-aminobutyric acid receptor subunit beta-154110
Gamma-aminobutyric acid receptor subunit delta54110
Gamma-aminobutyric acid receptor subunit gamma-254110
Gamma-aminobutyric acid receptor subunit alpha-554110
Gamma-aminobutyric acid receptor subunit alpha-354110
Gamma-aminobutyric acid receptor subunit gamma-154110
Gamma-aminobutyric acid receptor subunit alpha-254110
Mitogen-activated protein kinase 3 0101
Gamma-aminobutyric acid receptor subunit alpha-454110
Gamma-aminobutyric acid receptor subunit gamma-354110
Gamma-aminobutyric acid receptor subunit alpha-654110
Spike glycoprotein3115
Gamma-aminobutyric acid receptor subunit alpha-154110
Gamma-aminobutyric acid receptor subunit beta-354110
Gamma-aminobutyric acid receptor subunit beta-254110
Fatty-acid amide hydrolase 10101
Acid ceramidase0101
Acid ceramidase0101
GABA theta subunit54110
ATPase family AAA domain-containing protein 57007
Ataxin-27007
Angiotensin-converting enzyme 2 0112
Gamma-aminobutyric acid receptor subunit epsilon54110
Sulfide:quinone oxidoreductase, mitochondrial0101
activating transcription factor 66006
heat shock protein beta-14004
importin subunit beta-1 isoform 11001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
Rap guanine nucleotide exchange factor 33003
Glutathione S-transferase P0101
Alpha-tocopherol transfer protein0011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, Cruzipain1001
interleukin 82002
hypoxia-inducible factor 1 alpha subunit6006
caspase 7, apoptosis-related cysteine protease3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)2002
progesterone receptor9009
peroxisome proliferator-activated receptor delta6006
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
caspase-33003
RAD510101
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a6006
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Caspase-73003
Bloom syndrome protein isoform 14004
thyroid hormone receptor beta isoform a3003
caspase-33003
huntingtin isoform 22002
caspase-1 isoform alpha precursor1001
Voltage-dependent calcium channel gamma-2 subunit6006
ATP-dependent translocase ABCB10215
Glutamate receptor 26006
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-71001
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Epidermal growth factor receptor0303
Vascular endothelial growth factor receptor 20101
Alpha-synuclein1203
Lactoylglutathione lyase0101
Histone acetyltransferase p3000101
CREB-binding protein0101
Gamma-aminobutyric acid 0101
glp-1 receptor, partial4004
Gamma-aminobutyric acid receptor subunit pi0303
Gamma-aminobutyric acid receptor subunit delta0303
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Fatty acid-binding protein, liver0101
Alpha-1-acid glycoprotein 10001
Albumin0113
Albumin0011
Gamma-aminobutyric acid receptor subunit alpha-10404
Gamma-aminobutyric acid receptor subunit beta-10404
Neuronal acetylcholine receptor subunit alpha-40202
Gamma-aminobutyric acid receptor subunit alpha-20404
Gamma-aminobutyric acid receptor subunit alpha-30404
Neuronal acetylcholine receptor subunit beta-20202
Gamma-aminobutyric acid receptor subunit alpha-10336
Translocator protein0113
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10303
Gamma-aminobutyric acid receptor subunit gamma-20325
5-hydroxytryptamine receptor 1A0516
Gamma-aminobutyric acid receptor subunit alpha-40404
Gamma-aminobutyric acid receptor subunit gamma-20404
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30325
Translocator protein0101
Translocator protein0101
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50336
Gamma-aminobutyric acid receptor subunit alpha-30325
Gamma-aminobutyric acid receptor subunit alpha-20314
Gamma-aminobutyric acid receptor subunit beta-20314
Gamma-aminobutyric acid receptor subunit alpha-40303
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0303
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Neuronal acetylcholine receptor subunit alpha-70202
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0101
Gamma-aminobutyric acid receptor subunit alpha-60303
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10303
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit gamma-30303
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0303
thioredoxin reductase5005
SMAD family member 23003
ATAD5 protein, partial3003
SMAD family member 33003
Smad31001
IDH13003
nuclear factor erythroid 2-related factor 2 isoform 24004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor3003
DNA polymerase iota isoform a (long)2002
urokinase-type plasminogen activator precursor3003
plasminogen precursor3003
urokinase plasminogen activator surface receptor precursor3003
Vpr2002
Glutathione S-transferase omega-10101
TAR DNA-binding protein 434004
endonuclease IV3003
NFKB1 protein, partial1001
GALC protein1001
nonstructural protein 12002
arylsulfatase A4004
hexokinase-4 isoform 11001
peripheral myelin protein 22 isoform 12002
chromobox protein homolog 15005
glucokinase regulatory protein1001
Estrogen receptor0428
Sex hormone-binding globulin0011
Corticosteroid-binding globulin0101
Steryl-sulfatase0101
Aromatase0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
17-beta-hydroxysteroid dehydrogenase type 10203
Androgen receptor0404
Sodium-dependent serotonin transporter0606
Mu-type opioid receptor0011
5-hydroxytryptamine receptor 2B0606
Solute carrier organic anion transporter family member 1A10101
Mu-type opioid receptor0011
Inositol monophosphatase 11001
Cytochrome P450 1B10101
Estrogen receptor beta0326
Ghrelin O-acyltransferase0101
Broad substrate specificity ATP-binding cassette transporter ABCG20202
regulator of G-protein signaling 42002
cytochrome P450 2D6 isoform 12002
cytochrome P450 2C19 precursor1001
flap endonuclease 12002
muscleblind-like protein 1 isoform 12002
muscarinic acetylcholine receptor M12002
Bile salt export pump0202
Chain A, Uracil Phosphoribosyltransferase0101
Luciferase2002
Skn7p0001
pregnane X receptor2002
Thrombopoietin1001
hemoglobin subunit beta1001
serine/threonine-protein kinase mTOR isoform 12002
Solute carrier family 22 member 80001
Amyloid-beta precursor protein1001
Thymidylate synthase0101
HSP40, subfamily A [Plasmodium falciparum 3D7]0001
thyrotropin-releasing hormone receptor2002
Solute carrier family 22 member 60101
Carbonic anhydrase 120102
Carbonic anhydrase 10102
Carbonic anhydrase 20102
Carbonic anhydrase 30101
Glucose-6-phosphate 1-dehydrogenase0202
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Cytochrome P450 2J20101
6-phosphogluconate dehydrogenase, decarboxylating0202
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10202
Sodium/bile acid cotransporter0101
Carbonic anhydrase 90102
Multidrug and toxin extrusion protein 10101
Carbonic anhydrase 130102
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10202
Carbonic anhydrase 140102
Carbonic anhydrase 5B, mitochondrial0102
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Fumarate hydratase2002
polyprotein2002
bromodomain adjacent to zinc finger domain 2B2002
serine-protein kinase ATM isoform a1001
nuclear factor NF-kappa-B p105 subunit isoform 11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
M-phase phosphoprotein 82002
Aldo-keto reductase family 1 member B10404
Alpha-2A adrenergic receptor0404
Adenosine receptor A30404
Alpha-1B adrenergic receptor0404
Sodium-dependent noradrenaline transporter 0404
Alpha-1A adrenergic receptor0404
5-hydroxytryptamine receptor 60404
Sodium-dependent dopamine transporter 0404
Peroxisome proliferator-activated receptor alpha1001
Rap guanine nucleotide exchange factor 41001
GLS protein1001
alpha-galactosidase1001
Glutathione reductase, mitochondrial0101
Prostaglandin G/H synthase 10202
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 20101
Geranylgeranyl pyrophosphate synthase0101
Farnesyl pyrophosphate synthase0202
Hypoxanthine-guanine phosphoribosyltransferase0101
Farnesyl pyrophosphate synthase 0101
Solute carrier organic anion transporter family member 2A10102
Solute carrier organic anion transporter family member 2A10101
Solute carrier organic anion transporter family member 2B10001
Chain A, CES1 protein0101
DNA polymerase III, partial1001
glucocerebrosidase1001
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a1001
interferon gamma precursor0001
D(1A) dopamine receptor1001
transcriptional regulator ERG isoform 31001
ubiquitin-conjugating enzyme E2 N0101
ras-related protein Rab-9A1001
streptokinase A precursor0011
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
5-hydroxytryptamine receptor 40202
Serine/threonine-protein kinase D30101
Lysosomal acid glucosylceramidase0011
Receptor tyrosine-protein kinase erbB-20101
Integrin beta-31001
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Progesterone receptor0101
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Integrin alpha-IIb1001
Beta-1 adrenergic receptor0202
Muscarinic acetylcholine receptor M50202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Muscarinic acetylcholine receptor M10202
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Beta-3 adrenergic receptor0202
D(2) dopamine receptor0202
Protein kinase C alpha type0101
Alpha-2B adrenergic receptor0202
Muscarinic acetylcholine receptor M30202
Cytochrome P450 2B60101
Substance-K receptor0202
D(1A) dopamine receptor0202
D(4) dopamine receptor0202
UDP-glucuronosyltransferase 1A40001
Thromboxane-A synthase 0101
Protein kinase C eta type0101
Histamine H2 receptor0202
Alpha-1D adrenergic receptor0202
Substance-P receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0202
5-hydroxytryptamine receptor 1B0202
Adenosine receptor A2a0202
B2 bradykinin receptor0202
Adenosine receptor A10202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Delta-type opioid receptor0202
Kappa-type opioid receptor0202
Protein kinase C iota type0101
Melanocortin receptor 30202
Histamine H2 receptor1001
D(1A) dopamine receptor1001
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Potassium voltage-gated channel subfamily H member 20202
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Nuclear receptor subfamily 3 group C member 3 0202
Sigma non-opioid intracellular receptor 10202
Emopamil-binding protein-like0101
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]