Compounds > sulfotepp
Page last updated: 2024-12-06

sulfotepp

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

sulfotepp: analog of TEPP in which one keto-oxygen and one ether linked oxygen are replaced by sulfur atoms; insecticide; acaricide; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID19395
CHEMBL ID3182477
CHEBI ID38945
SCHEMBL ID35637
MeSH IDM0053992

Synonyms (126)

Synonym
o,o,o,o-tetraethyl-dithio-difosfaat [dutch]
hsdb 380
thiodiphosphoric acid (((ho)2p(s))2o), tetraethyl ester
ccris 4725
tetraethyl thiodiphosphate
epa pesticide chemical code 079501
ethyl thiopyrophosphate ((eto)2(ps)2o)
un1704
pyrophosphorodithioic acid, o,o,o,o-tetraethyl ester
thiodiphosphoric acid tetraethyl ester
pyrophosphoric acid, dithiono-, tetraethyl ester
rcra waste number p109
bis-o,o-diethylphosphorothionic anhydride
caswell no. 837
ai3-16273
sulfotepp [esa]
dithiopyrophosphate de tetraethyle [french]
o,o,o,o-tetraaethyl-dithionopyrophosphat [german]
asp 47
rcra waste no. p109
fulex
thiopyrophosphoric acid (((ho)2ps)2o), tetraethyl ester
o,o,o,o-tetraetil-ditio-pirofosfato [italian]
dithion (van)
nsc 66403
tetraethyldithiodifosfat [czech]
bayer-e 393
brn 1714019
einecs 222-995-2
sulfotep [bsi:iso]
tetraethyl thiopyrophosphate
dithiotep
ethyl thiopyrophosphate ([(eto)2ps]2o)
thiotepp
3689-24-5
ent 16,273
thiopyrophosphoric acid, tetraethyl ester
thiodiphosphoric acid ([(ho)2p(s)]2o), tetraethyl ester
bladafume
nsc-66403
tetraethyl dithionopyrophosphate
asp47
dithio (pesticide)
e393
nsc66403
ethyl thiopyrophosphate
wln: 2ops&o2&ops&o2&o2 -liquid mix
lethalaire g-57
di(thiophosphoric) acid, tetraethyl ester
bladafum
dithiopyrophosphate de tetraethyle
tetraethyl dithio pyrophosphate, liquid
o,o,o-tetraethyl dithiopyrophosphate
bladafun
thiopyrophosphoric acid ([(ho)2ps]2o), tetraethyl ester
pyrophosphorodithioic acid,o,o,o-tetraethyl ester
tedp
o,o,o-tetraetil-ditio-pirofosfato
dithion
o,o,o-tetraethyl-dithio-difosfaat
dithiofos
sulfatep
pyrophosphorodithioic acid, tetraethyl ester
sulfotepp
dithio
tetraethyl dithiopyrophosphate
sulfotep
bay-e-393
plantfume 103 smoke generator
tedtp
plant dithio aerosol
bis[o,o-diethylphosphorothionic] anhydride
dithione
dithiophos
pirofos
dithiodiphosphoric acid, tetraethyl ester
wln: 2ops&o2&ops&o2&o2
bis(o,o-diethylphosphorothionic) anhydride
o,o,o,o-tetraethyl dithiopyrophosphate
o,o,o,o-tetraethyl dithiodiphosphate
CHEBI:38945 ,
thiodiphosphoric acid, tetraethyl ester
tetraethyldithiopyrophosphate
NCGC00249112-01
NCGC00257084-01
tox21_303135
cas-3689-24-5
dtxsid7024328 ,
dtxcid804328
NCGC00259305-01
tox21_201756
bis-o,o-diethylphosphorothionic anhydrid
AKOS015960723
o,o,o,o-tetraetil-ditio-pirofosfato
v41bk2ee8x ,
tetraethyldithiodifosfat
4-01-00-01351 (beilstein handbook reference)
tetraethyl dithiopyrophosphate [un1704] [poison]
o,o,o,o-tetraaethyl-dithionopyrophosphat
unii-v41bk2ee8x
o,o,o,o-tetraethyl-dithio-difosfaat
e 393
o,o,o',o'-tetraethyl dithiopyrophosphate
SCHEMBL35637
sulfotep [hsdb]
sulfotep [iso]
sulfotep [mi]
thiodiphosphoric acid (((ho)(sub 2)p(s))(sub 2)o) tetraethyl ester
o,o,o'o'-tetraethyl dithiopyrophosphate
pyrophosphoric acid, tetraethyldithio-
XIUROWKZWPIAIB-UHFFFAOYSA-N
un 1704
o,o,o,o-tetraethyl dithiodiphosphate #
CHEMBL3182477
sulfotep, pestanal(r), analytical standard
sulfotep; tetraethyl dithionopyrophosphate
sulfotep 10 microg/ml in isooctane
diethoxyphosphinothioyloxy-diethoxy-sulfanylidene-lambda^{5}-phosphane
Q409772
DB11497
sulphotepp
thiodiphosphate, tetraethyl ester
diethoxyphosphinothioyloxy-diethoxy-sulfanylidene-lambda5-phosphane
tetra-o-ethyl dithiopyrophosphate
sulfotep 1000 microg/ml in acetonitrile
sulfotep 100 microg/ml in acetone
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (4)

RoleDescription
EC 3.1.1.7 (acetylcholinesterase) inhibitorAn EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid.
EC 3.1.1.8 (cholinesterase) inhibitorAn EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of cholinesterase (EC 3.1.1.8).
acaricideA substance used to destroy pests of the subclass Acari (mites and ticks).
agrochemicalAn agrochemical is a substance that is used in agriculture or horticulture.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
organic thiophosphate
organothiophosphate insecticide
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (7)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency56.40490.007215.758889.3584AID1224835
acetylcholinesteraseHomo sapiens (human)Potency30.47810.002541.796015,848.9004AID1347395; AID1347397; AID1347398; AID1347399
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency57.21000.003041.611522,387.1992AID1159552; AID1159553; AID1159555
retinoid X nuclear receptor alphaHomo sapiens (human)Potency62.48380.000817.505159.3239AID1159527
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency12.60200.001530.607315,848.9004AID1224841; AID1259401
thyroid stimulating hormone receptorHomo sapiens (human)Potency39.59290.001628.015177.1139AID1259385
Histone H2A.xCricetulus griseus (Chinese hamster)Potency11.60410.039147.5451146.8240AID1224845
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (42.86)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 37.52

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index37.52 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.36 (4.65)
Search Engine Demand Index50.49 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (37.52)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (14.29%)4.05%
Observational0 (0.00%)0.25%
Other6 (85.71%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
parathion
[no description available]		2.0310C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
avicide;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
mouse metabolite
chlorpyrifos
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.. chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group.		1.9710chloropyridine;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
diazinon
Diazinon: A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.. diazinon : A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4.		2.6830organic thiophosphate;
pyrimidines		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
nematicide;
xenobiotic
dimethoate
Dimethoate: An organothiophosphorus cholinesterase inhibitor that is used as a systemic and contact insecticide.. dimethoate : A monocarboxylic acid amide that is N-methylacetamide in which one of the hydrogens of the methyl group attached to the carbonyl moiety is replaced by a (dimethoxyphosphorothioyl)sulfanediyl group.		2.1510monocarboxylic acid amide;
organic thiophosphate		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic
disulfoton
Disulfoton: An organothiophosphate insecticide.. disulfoton : An organic thiophosphate that is the diethyl ester of S-[2-(ethylsulfanyl)ethyl] dihydrogen phosphorodithioate.		2.0310organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor
methyl parathion
Methyl Parathion: The methyl homolog of parathion. An effective, but highly toxic, organothiophosphate insecticide and cholinesterase inhibitor.. parathion-methyl : A C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4.		2.4820C-nitro compound;
organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
antifungal agent;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
genotoxin
phorate
Phorate: A cholinesterase inhibitor that is used as an insecticide.. phosphatidylcholine O-34:2 : A glycerophosphocholine that is an alkyl,acyl-sn-glycero-3-phosphocholine in which the alkyl or acyl groups at positions 1 and 2 contain a total of 34 carbons and 2 double bonds.		2.0310organic thiophosphate;
organothiophosphate insecticide		acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor
3,5,6-trichloro-2-pyridinol
3,5,6-trichloro-2-pyridinol: RN given refers to parent cpd. 3,5,6-trichloropyridine-2-one : A pyridone that is pyridin-2(1H)-one substituted by chloro groups at positions 3, 5 and 6. It is a metabolite of the agrochemical chlorpyrifos.. 3,5,6-trichloro-2-pyridinol : A hydroxypyridine that is pyridin-2-ol substituted by chloro groups at positions 3,5 and 6. It is a metabolite of the agrochemical chlorpyrifos.		1.9710chloropyridine;
hydroxypyridine;
pyridone		human urinary metabolite;
human xenobiotic metabolite;
marine xenobiotic metabolite
atropine
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate : A tropane alkaloid that is (1R,5)-8-methyl-8-azabicyclo[3.2.1]octane substituted by a (3-hydroxy-2-phenylpropanoyl)oxy group at position 3.		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials
Diseases, Occupational
[description not available]		01.9910
Agricultural Worker Disease
[description not available]		01.9910
Poisoning
Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.		06.9910