ametoctradin: an oomycete-specific fungicide [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ametoctradin : A member of the class of triazolopyrimidines that is [1,2,4]triazolo[1,5-a]pyrimidin-7-amine carrying additional ethyl and octyl substituents at positions 5 and 6 respectively. A fungicide for the control of late blight and downey mildew on potatoes and other crops including vines. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 15604010 |
| CHEBI ID | 83398 |
| SCHEMBL ID | 174682 |
| MeSH ID | M000610623 |
| Synonym |
|---|
| 865318-97-4 |
| 5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine |
| ametoctradin |
| J84P40P7BV , |
| bas-650f |
| resplend |
| ametoctradin [mi] |
| (1,2,4)triazolo(1,5-a)pyrimidin-7-amine, 5-ethyl-6-octyl- |
| percos |
| initium |
| zampro |
| enervin |
| orvego |
| 5-ethyl-6-octyl-(1,2,4)triazolo(1,5-a)pyrimidin-7-ylamine |
| GGKQIOFASHYUJZ-UHFFFAOYSA-N |
| 5-ethyl-6-octyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ylamine |
| 7-amino-5-ethyl-6-octyl[1,2,4]triazolo[1,5-a]pyrimidine |
| SCHEMBL174682 |
| 5-ethyl-6-octyl-1,2,4-triazolo(1,5-a)pyrimidine |
| unii-j84p40p7bv |
| CHEBI:83398 |
| DTXSID2058203 |
| 5-ethyl-6-octyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine |
| ametoctradin 100 microg/ml in acetonitrile |
| 5-ethyl-6-octyl-[1,2,3]triazolo[1,5-a]pyrimidin-7-amine |
| EN300-7492745 |
| [1,2,4]triazolo[1,5-a]pyrimidin-7-amine, 5-ethyl-6-octyl- |
| Z3014230115 |
Ametoctradin is a new Oomycete-specific fungicide under development by BASF. Ametoctradin inhibits the mitochondrial bc1 complex of oomycetes.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Ametoctradin is an agricultural fungicide that selectively inhibits the cytochrome bc" | ( The cytochrome bc Dreinert, A; Fehr, M; Mentzel, T; Meunier, B; Wolf, A, 2018) | 1.92 |
| "Ametoctradin is a new Oomycete-specific fungicide under development by BASF. " | ( Ametoctradin is a potent Qo site inhibitor of the mitochondrial respiration complex III. Ge, J; Liu, J; Yang, G; Zhang, M; Zhu, X, 2015) | 3.3 |
| "Ametoctradin is an agricultural fungicide that inhibits the mitochondrial bc1 complex of oomycetes. " | ( Binding of the respiratory chain inhibitor ametoctradin to the mitochondrial bc1 complex. Fehr, M; Stammler, G; Wolf, A, 2016) | 2.14 |
| Role | Description |
|---|---|
| mitochondrial cytochrome-bc1 complex inhibitor | null |
| antifungal agrochemical | Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| triazolopyrimidines | |
| aromatic amine | An amino compound in which the amino group is linked directly to an aromatic system. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (38.17) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||