Page last updated: 2024-11-12

fluopicolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

fluopicolide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

fluopicolide : A member of the class of benzamides obtained by formal condensation of the carboxy group of 2,6-dichlorobenzoic acid with the amino group of [3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylamine. A fungicide used for the control of a range of diseases including downy mildew and blight. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID11159021
CHEMBL ID3560526
CHEBI ID81764
SCHEMBL ID21950
MeSH IDM0556937

Synonyms (29)

Synonym
2,6-dichloro-n-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl]benzamide
239110-15-7
fluopicolide
2,6-dichloro-n-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)methyl)benzamide
fluopicolide [iso]
hsdb 7886
2,6-dichloro-n-(3-chloro-5-(trifluoromethyl)-2-pyridylmethyl)benzamide
ae c638206
unii-6tro75m67p
6tro75m67p ,
C18464
2,6-dichloro-n-[3-chloro-5-(trifluoromethyl)-2-pyridylmethyl]benzamide
fluopicolide [mi]
SCHEMBL21950
2,6-dichloro-n-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}benzamide
CHEBI:81764
NCGC00357081-01
dtxcid5014624
tox21_303793
dtxsid7034624 ,
cas-239110-15-7
2,6-dichloro-n-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)methyl)benzamide
CHEMBL3560526
fluopicolide, pestanal(r), analytical standard
fluopicolide 100 microg/ml in acetonitrile
J-015272
GBOYJIHYACSLGN-UHFFFAOYSA-N ,
Q13636695
benzamide, 2,6-dichloro-n-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methyl]-

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" The combination fungicide was sprayed thrice at the recommended dosage of 93."( Multilocation field trials for risk assessment of a combination fungicide Fluopicolide + Propamocarb in tomato.
Banerjee, H; Banerjee, T; Hudait, RK; Patel, AR; Patel, HK; Sahoo, SK; Shah, PG; Sharma, D; Sharma, KK; Shukla, VR; Singh, B; Tripathy, V; Vaghela, KM, 2016
)
0.67
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
antifungal agrochemicalAny substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (5)

ClassDescription
benzamides
organofluorine compoundAn organofluorine compound is a compound containing at least one carbon-fluorine bond.
monochloropyridineA chloropyridine in which only one chlorine is attached to the pyridine ring.
dichlorobenzeneAny member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
benzamide fungicideAn amide fungicide whose structure contains a benzamide moiety [ArC(=O)NR(1)R(2), where Ar represents phenyl or substituted phenyl].
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (16)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
hypoxia-inducible factor 1 alpha subunitHomo sapiens (human)Potency15.48453.189029.884159.4836AID1224846
RAR-related orphan receptor gammaMus musculus (house mouse)Potency12.19720.006038.004119,952.5996AID1159521; AID1159523
AR proteinHomo sapiens (human)Potency52.95890.000221.22318,912.5098AID1259243; AID1259247
caspase 7, apoptosis-related cysteine proteaseHomo sapiens (human)Potency19.33120.013326.981070.7614AID1346978
nuclear receptor subfamily 1, group I, member 3Homo sapiens (human)Potency6.80010.001022.650876.6163AID1224838; AID1224893
progesterone receptorHomo sapiens (human)Potency24.33650.000417.946075.1148AID1346795
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency17.22890.003041.611522,387.1992AID1159552
retinoid X nuclear receptor alphaHomo sapiens (human)Potency18.06670.000817.505159.3239AID1159527; AID1159531
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency48.98520.001530.607315,848.9004AID1224841; AID1224848; AID1224849; AID1259401; AID1259403
pregnane X nuclear receptorHomo sapiens (human)Potency1.21970.005428.02631,258.9301AID1346982
estrogen nuclear receptor alphaHomo sapiens (human)Potency44.21830.000229.305416,493.5996AID1259244; AID1259248
caspase-3Homo sapiens (human)Potency19.33120.013326.981070.7614AID1346978
Caspase-7Cricetulus griseus (Chinese hamster)Potency21.68990.006723.496068.5896AID1346980
caspase-3Cricetulus griseus (Chinese hamster)Potency21.68990.006723.496068.5896AID1346980
Voltage-dependent calcium channel gamma-2 subunitMus musculus (house mouse)Potency61.13060.001557.789015,848.9004AID1259244
Glutamate receptor 2Rattus norvegicus (Norway rat)Potency61.13060.001551.739315,848.9004AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Ceullar Components (1)

Processvia Protein(s)Taxonomy
plasma membraneGlutamate receptor 2Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (63.64)24.3611
2020's4 (36.36)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 36.47

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index36.47 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.69 (4.65)
Search Engine Demand Index71.02 (26.88)
Search Engine Supply Index3.08 (0.95)

This Compound (36.47)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]