n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide profile

N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

fenhexamid : An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

ID Source	ID
PubMed CID	213031
CHEMBL ID	1688541
CHEBI ID	81853
SCHEMBL ID	23092
MeSH ID	M0419957

Synonym
LS-14298
fenhexamid [iso:bsi]
teldor
elevate
cyclohexanecarboxamide, n-(2,3-dichloro-4-hydroxyphenyl)-1-methyl-
hsdb 7273
kbr 2738
NCGC00163791-01
126833-17-8
fenhexamid
n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide
NCGC00163791-02
kbr2738
kbr-2738
FT-0668488
CHEMBL1688541
chebi:81853 ,
n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexane-1-carboxamide
NCGC00163791-03
C18593
cas-126833-17-8
NCGC00254944-01
tox21_301042
dtxsid3032549 ,
dtxcid1012549
unii-q68c3c9p1u
q68c3c9p1u ,
decree
AKOS015903660
fenhexamid [iso]
fenhexamid [hsdb]
1-methyl-cyclohexanecarboxylic acid (2,3-dichloro-4-hydroxy-phenyl)-amide
2',3'-dichloro-4'-hydroxy-1-methylcyclohexanecarboxanilide
fenhexamid [mi]
SCHEMBL23092
fenhexamide
n-(2,3-dichloro-4-hydroxy-phenyl)-1-methyl-cyclohexanecarboxamide
VDLGAVXLJYLFDH-UHFFFAOYSA-N
J-005440
fenhexamid, pestanal(r), analytical standard
fenhexamid 10 microg/ml in cyclohexane
mfcd03095700
teldor; elevate;kbr 2738
F0967
Q63395375
AMY40772
T71668
HY-118065
CS-0065121

Role	Description
EC 1.14.13.72 (methylsterol monooxygenase) inhibitor	An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72).
sterol biosynthesis inhibitor	Any compound that inhibits the biosynthesis of any sterol.
antifungal agrochemical	Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Class	Description
monocarboxylic acid amide	A carboxamide derived from a monocarboxylic acid.
phenols	Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring.
aromatic amide	An amide in which the amide linkage is bonded directly to an aromatic system.
dichlorobenzene	Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions.
anilide fungicide	Any amide fungicide whose structure contains an anilide group.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein	Taxonomy	Measurement	Average (µ)	Min (ref.)	Avg (ref.)	Max (ref.)	Bioassay(s)
GLI family zinc finger 3	Homo sapiens (human)	Potency	28.7093	0.0007	14.5928	83.7951	AID1259369; AID1259392
AR protein	Homo sapiens (human)	Potency	40.7376	0.0002	21.2231	8,912.5098	AID1259243; AID1259247; AID743035; AID743036; AID743042; AID743054; AID743063
estrogen receptor 2 (ER beta)	Homo sapiens (human)	Potency	24.3365	0.0006	57.9133	22,387.1992	AID1259377; AID1259378
nuclear receptor subfamily 1, group I, member 3	Homo sapiens (human)	Potency	2.4337	0.0010	22.6508	76.6163	AID1224838
progesterone receptor	Homo sapiens (human)	Potency	27.3060	0.0004	17.9460	75.1148	AID1346795
glucocorticoid receptor [Homo sapiens]	Homo sapiens (human)	Potency	43.6412	0.0002	14.3764	60.0339	AID720692
estrogen-related nuclear receptor alpha	Homo sapiens (human)	Potency	62.6224	0.0015	30.6073	15,848.9004	AID1224841; AID1224848; AID1224849; AID1259401; AID1259403
farnesoid X nuclear receptor	Homo sapiens (human)	Potency	27.4709	0.3758	27.4851	61.6524	AID588527; AID743217
pregnane X nuclear receptor	Homo sapiens (human)	Potency	34.7249	0.0054	28.0263	1,258.9301	AID1346982; AID720659
estrogen nuclear receptor alpha	Homo sapiens (human)	Potency	53.5673	0.0002	29.3054	16,493.5996	AID1259244; AID743069; AID743075; AID743077; AID743078; AID743079
vitamin D (1,25- dihydroxyvitamin D3) receptor	Homo sapiens (human)	Potency	0.0616	0.0237	23.2282	63.5986	AID743223
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	Homo sapiens (human)	Potency	68.5896	0.0017	23.8393	78.1014	AID743083
v-jun sarcoma virus 17 oncogene homolog (avian)	Homo sapiens (human)	Potency	50.1448	0.0578	21.1097	61.2679	AID1159526; AID1159528
thyroid hormone receptor beta isoform 2	Rattus norvegicus (Norway rat)	Potency	68.5896	0.0003	23.4451	159.6830	AID743065; AID743067
nuclear factor erythroid 2-related factor 2 isoform 1	Homo sapiens (human)	Potency	33.6300	0.0006	27.2152	1,122.0200	AID651741; AID720636; AID743202; AID743219
Voltage-dependent calcium channel gamma-2 subunit	Mus musculus (house mouse)	Potency	76.9588	0.0015	57.7890	15,848.9004	AID1259244
Cellular tumor antigen p53	Homo sapiens (human)	Potency	68.5896	0.0023	19.5956	74.0614	AID651631
Glutamate receptor 2	Rattus norvegicus (Norway rat)	Potency	76.9588	0.0015	51.7393	15,848.9004	AID1259244
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Process	via Protein(s)	Taxonomy
negative regulation of cell population proliferation	Cellular tumor antigen p53	Homo sapiens (human)
regulation of cell cycle	Cellular tumor antigen p53	Homo sapiens (human)
regulation of cell cycle G2/M phase transition	Cellular tumor antigen p53	Homo sapiens (human)
DNA damage response	Cellular tumor antigen p53	Homo sapiens (human)
ER overload response	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to glucose starvation	Cellular tumor antigen p53	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
regulation of apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of miRNA transcription	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of transcription by RNA polymerase II	Cellular tumor antigen p53	Homo sapiens (human)
mitophagy	Cellular tumor antigen p53	Homo sapiens (human)
in utero embryonic development	Cellular tumor antigen p53	Homo sapiens (human)
somitogenesis	Cellular tumor antigen p53	Homo sapiens (human)
release of cytochrome c from mitochondria	Cellular tumor antigen p53	Homo sapiens (human)
hematopoietic progenitor cell differentiation	Cellular tumor antigen p53	Homo sapiens (human)
T cell proliferation involved in immune response	Cellular tumor antigen p53	Homo sapiens (human)
B cell lineage commitment	Cellular tumor antigen p53	Homo sapiens (human)
T cell lineage commitment	Cellular tumor antigen p53	Homo sapiens (human)
response to ischemia	Cellular tumor antigen p53	Homo sapiens (human)
nucleotide-excision repair	Cellular tumor antigen p53	Homo sapiens (human)
double-strand break repair	Cellular tumor antigen p53	Homo sapiens (human)
regulation of DNA-templated transcription	Cellular tumor antigen p53	Homo sapiens (human)
regulation of transcription by RNA polymerase II	Cellular tumor antigen p53	Homo sapiens (human)
protein import into nucleus	Cellular tumor antigen p53	Homo sapiens (human)
autophagy	Cellular tumor antigen p53	Homo sapiens (human)
DNA damage response	Cellular tumor antigen p53	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	Cellular tumor antigen p53	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
transforming growth factor beta receptor signaling pathway	Cellular tumor antigen p53	Homo sapiens (human)
Ras protein signal transduction	Cellular tumor antigen p53	Homo sapiens (human)
gastrulation	Cellular tumor antigen p53	Homo sapiens (human)
neuroblast proliferation	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of neuroblast proliferation	Cellular tumor antigen p53	Homo sapiens (human)
protein localization	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of DNA replication	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of cell population proliferation	Cellular tumor antigen p53	Homo sapiens (human)
determination of adult lifespan	Cellular tumor antigen p53	Homo sapiens (human)
mRNA transcription	Cellular tumor antigen p53	Homo sapiens (human)
rRNA transcription	Cellular tumor antigen p53	Homo sapiens (human)
response to salt stress	Cellular tumor antigen p53	Homo sapiens (human)
response to inorganic substance	Cellular tumor antigen p53	Homo sapiens (human)
response to X-ray	Cellular tumor antigen p53	Homo sapiens (human)
response to gamma radiation	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of gene expression	Cellular tumor antigen p53	Homo sapiens (human)
cardiac muscle cell apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of cardiac muscle cell apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
glial cell proliferation	Cellular tumor antigen p53	Homo sapiens (human)
viral process	Cellular tumor antigen p53	Homo sapiens (human)
glucose catabolic process to lactate via pyruvate	Cellular tumor antigen p53	Homo sapiens (human)
cerebellum development	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of cell growth	Cellular tumor antigen p53	Homo sapiens (human)
DNA damage response, signal transduction by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of transforming growth factor beta receptor signaling pathway	Cellular tumor antigen p53	Homo sapiens (human)
mitotic G1 DNA damage checkpoint signaling	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of telomere maintenance via telomerase	Cellular tumor antigen p53	Homo sapiens (human)
T cell differentiation in thymus	Cellular tumor antigen p53	Homo sapiens (human)
tumor necrosis factor-mediated signaling pathway	Cellular tumor antigen p53	Homo sapiens (human)
regulation of tissue remodeling	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to UV	Cellular tumor antigen p53	Homo sapiens (human)
multicellular organism growth	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of mitochondrial membrane permeability	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to glucose starvation	Cellular tumor antigen p53	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
entrainment of circadian clock by photoperiod	Cellular tumor antigen p53	Homo sapiens (human)
mitochondrial DNA repair	Cellular tumor antigen p53	Homo sapiens (human)
regulation of DNA damage response, signal transduction by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of neuron apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
transcription initiation-coupled chromatin remodeling	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of proteolysis	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of DNA-templated transcription	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of DNA-templated transcription	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of RNA polymerase II transcription preinitiation complex assembly	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of transcription by RNA polymerase II	Cellular tumor antigen p53	Homo sapiens (human)
response to antibiotic	Cellular tumor antigen p53	Homo sapiens (human)
fibroblast proliferation	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of fibroblast proliferation	Cellular tumor antigen p53	Homo sapiens (human)
circadian behavior	Cellular tumor antigen p53	Homo sapiens (human)
bone marrow development	Cellular tumor antigen p53	Homo sapiens (human)
embryonic organ development	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of peptidyl-tyrosine phosphorylation	Cellular tumor antigen p53	Homo sapiens (human)
protein stabilization	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of helicase activity	Cellular tumor antigen p53	Homo sapiens (human)
protein tetramerization	Cellular tumor antigen p53	Homo sapiens (human)
chromosome organization	Cellular tumor antigen p53	Homo sapiens (human)
neuron apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
regulation of cell cycle	Cellular tumor antigen p53	Homo sapiens (human)
hematopoietic stem cell differentiation	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of glial cell proliferation	Cellular tumor antigen p53	Homo sapiens (human)
type II interferon-mediated signaling pathway	Cellular tumor antigen p53	Homo sapiens (human)
cardiac septum morphogenesis	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of programmed necrotic cell death	Cellular tumor antigen p53	Homo sapiens (human)
protein-containing complex assembly	Cellular tumor antigen p53	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	Cellular tumor antigen p53	Homo sapiens (human)
thymocyte apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of thymocyte apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
necroptotic process	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to hypoxia	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to xenobiotic stimulus	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to ionizing radiation	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to gamma radiation	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to UV-C	Cellular tumor antigen p53	Homo sapiens (human)
stem cell proliferation	Cellular tumor antigen p53	Homo sapiens (human)
signal transduction by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
intrinsic apoptotic signaling pathway by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
reactive oxygen species metabolic process	Cellular tumor antigen p53	Homo sapiens (human)
cellular response to actinomycin D	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of release of cytochrome c from mitochondria	Cellular tumor antigen p53	Homo sapiens (human)
cellular senescence	Cellular tumor antigen p53	Homo sapiens (human)
replicative senescence	Cellular tumor antigen p53	Homo sapiens (human)
oxidative stress-induced premature senescence	Cellular tumor antigen p53	Homo sapiens (human)
intrinsic apoptotic signaling pathway	Cellular tumor antigen p53	Homo sapiens (human)
oligodendrocyte apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of execution phase of apoptosis	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of mitophagy	Cellular tumor antigen p53	Homo sapiens (human)
regulation of mitochondrial membrane permeability involved in apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
regulation of intrinsic apoptotic signaling pathway by p53 class mediator	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of miRNA transcription	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of G1 to G0 transition	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of miRNA processing	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of glucose catabolic process to lactate via pyruvate	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of pentose-phosphate shunt	Cellular tumor antigen p53	Homo sapiens (human)
intrinsic apoptotic signaling pathway in response to hypoxia	Cellular tumor antigen p53	Homo sapiens (human)
regulation of fibroblast apoptotic process	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of reactive oxygen species metabolic process	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of reactive oxygen species metabolic process	Cellular tumor antigen p53	Homo sapiens (human)
negative regulation of stem cell proliferation	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of cellular senescence	Cellular tumor antigen p53	Homo sapiens (human)
positive regulation of intrinsic apoptotic signaling pathway	Cellular tumor antigen p53	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
transcription cis-regulatory region binding	Cellular tumor antigen p53	Homo sapiens (human)
RNA polymerase II cis-regulatory region sequence-specific DNA binding	Cellular tumor antigen p53	Homo sapiens (human)
DNA-binding transcription factor activity, RNA polymerase II-specific	Cellular tumor antigen p53	Homo sapiens (human)
cis-regulatory region sequence-specific DNA binding	Cellular tumor antigen p53	Homo sapiens (human)
core promoter sequence-specific DNA binding	Cellular tumor antigen p53	Homo sapiens (human)
TFIID-class transcription factor complex binding	Cellular tumor antigen p53	Homo sapiens (human)
DNA-binding transcription repressor activity, RNA polymerase II-specific	Cellular tumor antigen p53	Homo sapiens (human)
DNA-binding transcription activator activity, RNA polymerase II-specific	Cellular tumor antigen p53	Homo sapiens (human)
protease binding	Cellular tumor antigen p53	Homo sapiens (human)
p53 binding	Cellular tumor antigen p53	Homo sapiens (human)
DNA binding	Cellular tumor antigen p53	Homo sapiens (human)
chromatin binding	Cellular tumor antigen p53	Homo sapiens (human)
DNA-binding transcription factor activity	Cellular tumor antigen p53	Homo sapiens (human)
mRNA 3'-UTR binding	Cellular tumor antigen p53	Homo sapiens (human)
copper ion binding	Cellular tumor antigen p53	Homo sapiens (human)
protein binding	Cellular tumor antigen p53	Homo sapiens (human)
zinc ion binding	Cellular tumor antigen p53	Homo sapiens (human)
enzyme binding	Cellular tumor antigen p53	Homo sapiens (human)
receptor tyrosine kinase binding	Cellular tumor antigen p53	Homo sapiens (human)
ubiquitin protein ligase binding	Cellular tumor antigen p53	Homo sapiens (human)
histone deacetylase regulator activity	Cellular tumor antigen p53	Homo sapiens (human)
ATP-dependent DNA/DNA annealing activity	Cellular tumor antigen p53	Homo sapiens (human)
identical protein binding	Cellular tumor antigen p53	Homo sapiens (human)
histone deacetylase binding	Cellular tumor antigen p53	Homo sapiens (human)
protein heterodimerization activity	Cellular tumor antigen p53	Homo sapiens (human)
protein-folding chaperone binding	Cellular tumor antigen p53	Homo sapiens (human)
protein phosphatase 2A binding	Cellular tumor antigen p53	Homo sapiens (human)
RNA polymerase II-specific DNA-binding transcription factor binding	Cellular tumor antigen p53	Homo sapiens (human)
14-3-3 protein binding	Cellular tumor antigen p53	Homo sapiens (human)
MDM2/MDM4 family protein binding	Cellular tumor antigen p53	Homo sapiens (human)
disordered domain specific binding	Cellular tumor antigen p53	Homo sapiens (human)
general transcription initiation factor binding	Cellular tumor antigen p53	Homo sapiens (human)
molecular function activator activity	Cellular tumor antigen p53	Homo sapiens (human)
promoter-specific chromatin binding	Cellular tumor antigen p53	Homo sapiens (human)
[Information is prepared from geneontology information from the June-17-2024 release]

Process	via Protein(s)	Taxonomy
nuclear body	Cellular tumor antigen p53	Homo sapiens (human)
nucleus	Cellular tumor antigen p53	Homo sapiens (human)
nucleoplasm	Cellular tumor antigen p53	Homo sapiens (human)
replication fork	Cellular tumor antigen p53	Homo sapiens (human)
nucleolus	Cellular tumor antigen p53	Homo sapiens (human)
cytoplasm	Cellular tumor antigen p53	Homo sapiens (human)
mitochondrion	Cellular tumor antigen p53	Homo sapiens (human)
mitochondrial matrix	Cellular tumor antigen p53	Homo sapiens (human)
endoplasmic reticulum	Cellular tumor antigen p53	Homo sapiens (human)
centrosome	Cellular tumor antigen p53	Homo sapiens (human)
cytosol	Cellular tumor antigen p53	Homo sapiens (human)
nuclear matrix	Cellular tumor antigen p53	Homo sapiens (human)
PML body	Cellular tumor antigen p53	Homo sapiens (human)
transcription repressor complex	Cellular tumor antigen p53	Homo sapiens (human)
site of double-strand break	Cellular tumor antigen p53	Homo sapiens (human)
germ cell nucleus	Cellular tumor antigen p53	Homo sapiens (human)
chromatin	Cellular tumor antigen p53	Homo sapiens (human)
transcription regulator complex	Cellular tumor antigen p53	Homo sapiens (human)
protein-containing complex	Cellular tumor antigen p53	Homo sapiens (human)
plasma membrane	Glutamate receptor 2	Rattus norvegicus (Norway rat)
[Information is prepared from geneontology information from the June-17-2024 release]

Bioassays (121)

Assay ID	Title	Year	Journal	Article
AID582544	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 520a assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582540	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 440a assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582671	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg F412I mutant at 2 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112895	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for wild type Oculimacula yallundae TriS by mycelial growth inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID1112881	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 to EC50 for wild type Oculimacula yallundae TriS by germ tube elongation assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582666	Antifungal activity against Botrytis cinerea B05.10 harboring TELerg F412S mutant assessed as appearance of mycelium growth up to 20 ug/ml	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582634	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-AVB assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582673	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg N369D mutant at 5 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582635	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-PV Reims assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582614	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea MK3-9 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582630	Antifungal activity against fenhexamid-senistive Botrytis cinerea B05.10 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582653	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 05-ABA assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112893	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for wild type Oculimacula yallundae TriS by mycelial growth inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582528	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-221 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112129	Antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582641	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 264 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582626	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 453b assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582654	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 57 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112892	Fungicidal activity against Oculimacula acuformis assessed as inhibition of germ tube elongation incubated at 19 degC in dark for 48 hr	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582538	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 379a assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112171	Protective antifungal activity against Botryotinia fuckeliana inoculated in fungicide-applied strawberry fruit assessed as disease control efficacy at 100 ug AI/ml applied 48 hr prior inoculation relative to control	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID1112166	Protective antifungal activity against Botryotinia fuckeliana inoculated in fungicide-applied strawberry fruit assessed as disease severity measuring lesion diameter at 100 ug AI/ml applied 24 hr prior inoculation	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID1112161	Protective antifungal activity against Botryotinia fuckeliana inoculated in fungicide-applied strawberry fruit assessed as disease control efficacy at 100 ug AI/ml applied 24 hr prior inoculation relative to control	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582664	Antifungal activity against Botrytis cinerea 223b expressing erg27 HydR3+ alleles assessed as appearance of dense mycelium up to 20 ug/ml	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582616	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea MK5-2 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582620	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 202 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112879	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by germ tube elongation assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582655	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 202 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582722	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg F412I mutant at 5 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582726	Antifungal activity against Botrytis cinerea 286 harboring TELerg S336C mutant at 10 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582537	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 312 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112110	Protective antifungal activity against Botryotinia fuckeliana inoculated in fungicide-applied strawberry fruit assessed as disease severity measuring lesion diameter at 100 ug AI/ml applied 96 hr prior-inoculation	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582669	Antifungal activity against Botrytis cinerea 286 harboring TELerg S336C mutant at 1 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582624	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 452 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582534	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 223a assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582650	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 520b assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582638	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 214 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582628	Antifungal activity against fenhexamid-senistive Botrytis cinerea SAS405 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582649	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 520a assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112882	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by mycelial growth inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID1112888	Fungicidal activity against Oculimacula yallundae assessed as inhibition of mycelial growth in presence of 10 g glucose incubated at 19 degC in dark for 4 weeks	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582631	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 1837 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582660	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 453a assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582663	Antifungal activity against Botrytis cinerea 1837 expressing erg27 HydR3+ alleles assessed as appearance of dense mycelium up to 20 ug/ml	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582526	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 1837 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582543	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 506b assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582545	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 520b assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582639	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 223a assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582536	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 264 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112877	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by germ tube elongation assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582632	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-190 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112880	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for wild type Oculimacula yallundae TriS by germ tube elongation assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582533	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 214 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112156	Curative antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit assessed as disease severity measuring lesion diameter at 100 ug AI/ml applied 48 hr post-inoculation	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582532	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 179 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112889	Fungicidal activity against Oculimacula acuformis assessed as inhibition of mycelial growth in presence of 10 g glucose incubated at 19 degC in dark for 4 weeks	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID1112146	Curative antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit assessed as disease severity measuring lesion diameter at 100 ug AI/ml applied 24 hr post-inoculation	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582524	Antifungal activity against fenhexamid-senistive Botrytis cinerea SAS405 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582541	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 440b assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112131	Curative antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit assessed as disease control efficacy at 100 ug AI/ml applied 96 hr post-inoculation relative to control	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582670	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg N369D mutant at 2 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582647	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 506a assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582640	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 223b assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582648	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 506b assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582657	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 286 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112141	Curative antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit assessed as disease control efficacy at 100 ug AI/ml applied 24 hr post-inoculation relative to control	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582643	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 379a assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582621	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 221 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582542	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 506a assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582549	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea MK3-36 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582668	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg F412I mutant at 1 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582539	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 379b assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112885	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 to EC50 for wild type Oculimacula yallundae TriS by mycelial growth inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582546	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 533 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582652	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 05-1.27 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112887	Selectivity index, ratio of EC50 for Oculimacula acuformis to EC50 for Oculimacula yallundae in presence of 10 g glucose by mycelial growth inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582659	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 452 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582658	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 365 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582623	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 365 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582642	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 312 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582724	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg N369D mutant at 10 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582525	Antifungal activity against fenhexamid-senistive Botrytis cinerea B05.10 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582615	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea MK5-14 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582618	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 05-ABA assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582633	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-221 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582723	Antifungal activity against Botrytis cinerea 286 harboring TELerg S336C mutant at 5 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582547	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea MK3-1 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582535	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 223b assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582531	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 118 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582629	Antifungal activity against fenhexamid-senistive Botrytis cinerea SAS56 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582627	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 454 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112176	Protective antifungal activity against Botryotinia fuckeliana inoculated in fungicide-applied strawberry fruit assessed as disease severity measuring lesion diameter at 100 ug AI/ml applied 48 hr prior inoculation	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582625	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 453a assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112181	Protective antifungal activity against Botryotinia fuckeliana inoculated in fungicide-applied strawberry fruit assessed as disease control efficacy at 100 ug AI/ml applied 96 hr prior-inoculation relative to control	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582523	Antifungal activity against fenhexamid-senistive Botrytis cinerea SAS56 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582665	Antifungal activity against Botrytis cinerea B05.10 harboring TELerg F412I mutant assessed as appearance of mycelium growth up to 20 ug/ml	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582667	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg N369D mutant at 1 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582527	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-190 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582617	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 05-1.27 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582646	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 440b assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112894	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR2 to EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae TriR1 by mycelial growth inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582622	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 286 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582619	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 57 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582662	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 454 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112890	Selectivity index, ratio of EC50 for Oculimacula acuformis to EC50 for Oculimacula yallundae by germ tube elongation inhibition assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582725	Antifungal activity against HydR3 deficient Botrytis cinerea 453 harboring TELerg F412I mutant at 10 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582672	Antifungal activity against Botrytis cinerea 286 harboring TELerg S336C mutant at 2 ug/ml relative to wild-type	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112136	Curative antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit assessed as disease severity measuring lesion diameter at 100 ug AI/ml applied 96 hr post-inoculation	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582661	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 453b assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112151	Curative antifungal activity against Botryotinia fuckeliana inoculated in strawberry fruit assessed as disease control efficacy at 100 ug AI/ml applied 48 hr post-inoculation relative to control	2012	Pest management science, Jun, Volume: 68, Issue:6	Biological activity of the succinate dehydrogenase inhibitor fluopyram against Botrytis cinerea and fungal baseline sensitivity.
AID582656	Antifungal activity against moderately to slightly fenhexamid-resistant Botrytis cinerea 221 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112891	Fungicidal activity against Oculimacula yallundae assessed as inhibition of germ tube elongation incubated at 19 degC in dark for 48 hr	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582529	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-AVB assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582644	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 379b assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582636	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 118 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582645	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 440a assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID1112878	Resistance index, ratio of EC50 for sterol 14alpha-demethylation inhibitor-resistant Oculimacula yallundae MDR to EC50 for wild type Oculimacula yallundae TriS by germ tube elongation assay	2013	Pest management science, Jan, Volume: 69, Issue:1	Fungicide resistance status in French populations of the wheat eyespot fungi Oculimacula acuformis and Oculimacula yallundae.
AID582637	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 179 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582530	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 05-PV Reims assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582651	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea 533 assessed as inhibition of mycelium growth measured over 5 days	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
AID582548	Antifungal activity against highly fenhexamid-resistant Botrytis cinerea MK3-31 assessed as inhibition of germ tube elongation after 24 hrs	2008	Antimicrobial agents and chemotherapy, Nov, Volume: 52, Issue:11	Genetic analysis of fenhexamid-resistant field isolates of the phytopathogenic fungus Botrytis cinerea.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	18 (38.30)	29.6817
2010's	25 (53.19)	24.3611
2020's	4 (8.51)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (2.08%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	47 (97.92%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
niacinamide nicotinamide : A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group.	2.17	1	pyridine alkaloid; pyridinecarboxamide; vitamin B3	anti-inflammatory agent; antioxidant; cofactor; EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor; EC 3.5.1.98 (histone deacetylase) inhibitor; Escherichia coli metabolite; geroprotector; human urinary metabolite; metabolite; mouse metabolite; neuroprotective agent; Saccharomyces cerevisiae metabolite; Sir2 inhibitor
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.17	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
atrazine [no description available]	2.08	1	chloro-1,3,5-triazine; diamino-1,3,5-triazine	environmental contaminant; herbicide; xenobiotic
liquid crystal polymer bromuconazole: a fungicide; structure in first source. bromuconazole : A member of the class of oxolanes carrying 1,2,4-triazol-ylmethyl and 2,4-dichlorophenyl substituents at position 2 as well as a bromo substituent at position 4. A foliar applied conazole fungicide for a range of crops including cereals, fruit, vegetables and vines.	3.18	1	conazole fungicide; dichlorobenzene; organobromine compound; oxolanes; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor
tolnaftate [no description available]	3.18	1	monothiocarbamic ester	antifungal drug
alanine Alanine: A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM.. alanine : An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2.	2.31	1	alanine zwitterion; alanine; L-alpha-amino acid; proteinogenic amino acid; pyruvate family amino acid	EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor; fundamental metabolite
systhane systhane: structure in first source. 2-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)hexanenitrile : A nitrile that is hexanenitrile substituted at the 2-position by p-chlorophenyl and (1,2,4-triazol-1-yl)methyl groups.	2.1	1	monochlorobenzenes; nitrile; triazoles
4-butyrolactone 4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.	2.31	1	butan-4-olide	metabolite; neurotoxin
pyrroles 1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen.	2.47	2	pyrrole; secondary amine
thiophenes Thiophenes: A monocyclic heteroarene furan in which the oxygen atom is replaced by a sulfur.. thiophenes : Compounds containing at least one thiophene ring.	2.17	1	mancude organic heteromonocyclic parent; monocyclic heteroarene; thiophenes; volatile organic compound	non-polar solvent
captan Captan: One of the phthalimide fungicides.. captan : A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops.	2.17	1	isoindoles; organochlorine compound; organosulfur compound; phthalimide fungicide	antifungal agrochemical
oxazoles Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom.	2.74	3	1,3-oxazoles; mancude organic heteromonocyclic parent; monocyclic heteroarene
aminoimidazole carboxamide Aminoimidazole Carboxamide: An imidazole derivative which is a metabolite of the antineoplastic agents BIC and DIC. By itself, or as the ribonucleotide, it is used as a condensation agent in the preparation of nucleosides and nucleotides. Compounded with orotic acid, it is used to treat liver diseases.. 5-aminoimidazole-4-carboxamide : An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.	2.07	1	aminoimidazole; monocarboxylic acid amide	mouse metabolite
hydantoins Hydantoins: Compounds based on imidazolidine dione. Some derivatives are ANTICONVULSANTS.. imidazolidine-2,4-dione : An imidazolidinone with oxo groups at position 2 and 4.	2.07	1	imidazolidine-2,4-dione
n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamide N-dichlorofluoromethylthio-N',N'-dimethyl-N-p-tolylsulfamide: an endocrine disruptor; structure given in first source. tolylfluanid : A member of the class of sulfamides that is dichlofluanid in which the hydrogen at the para position of the phenyl group is replaced by a methyl group. A fungicide first marketed in 1971 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union.	2.01	1	organochlorine compound; organofluorine compound; phenylsulfamide fungicide; sulfamides	antifungal agrochemical; genotoxin
carboxin Carboxin: A systemic agricultural fungicide and seed treatment agent.. carboxin : An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment.	3.18	1	anilide fungicide; anilide; enamide; organosulfur heterocyclic compound; oxacycle; secondary carboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor
titanium Titanium: A dark-gray, metallic element of widespread distribution but occurring in small amounts with atomic number, 22, atomic weight, 47.867 and symbol, Ti; specific gravity, 4.5; used for fixation of fractures.	2.06	1	titanium group element atom
carbendazim carbendazim: carcinogen when combined with sodium nitrite; principle metabolite of thiophanate methyl & benomyl; structure. carbendazim : A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables.	3.58	2	benzimidazole fungicide; benzimidazoles; benzimidazolylcarbamate fungicide; carbamate ester	antifungal agrochemical; antinematodal drug; metabolite; microtubule-destabilising agent
titanium dioxide titanium dioxide: used medically as protectant against externally caused irritation & sunlight; high concentrations of dust may cause irritation to respiratory tract; RN given refers to titanium oxide (TiO2); structure. titanium dioxide : A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.	2.06	1	titanium oxides	food colouring
phenyl acetate phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.	2.44	2	benzenes; phenyl acetates
bikaverin bikaverin : A organic heterotetracyclic compound that is 10H-benzo[b]xanthene-7,10,12-trione substituted by hydroxy groups at positions 6 and 11, methoxy groups at positions 3 and 8 and a methyl group at position 1.	2.08	1
iprodione iprodione : An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide.	2.48	2	benzenes; dichlorophenyl dicarboximide fungicide; imidazole fungicide; imidazolidine-2,4-dione; ureas	antifungal agrochemical; nematicide
triadimefon 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one : A member of the class of triazoles that is 1-hydroxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one in which the hydroxyl hydrogen is replaced by a 4-chlorophenyl group.	2.08	1	aromatic ether; hemiaminal ether; ketone; monochlorobenzenes; triazoles
deoxynivalenol deoxynivalenol : A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination.	2.08	1	cyclic ketone; enone; primary alcohol; secondary alpha-hydroxy ketone; trichothecene; triol	mycotoxin
decamethrin decamethrin: pyrethroid insecticide; RN given refers to cpd without isomeric designation; structure	2.15	1	aromatic ether; cyclopropanecarboxylate ester; nitrile; organobromine compound	agrochemical; antifeedant; calcium channel agonist; EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor; pyrethroid ester insecticide
metalaxyl metalaxyl: RN given refers to (DL-Ala)-isomer. metalaxyl : A racemate comprising equal amounts of (R)- and (S)-metalaxyl. A systemic fungicide, it is active against phytopathogens of the order Peronosporales and is used to conrtrol Pythium in a number of vegetable crops.. methyl N-(2,6-dimethylphenyl)-N-(methoxyacetyl)alaninate : An alanine derivative that is methyl alaninate in which one of the hydrogens attached to the nitrogen is substituted by a methoxyacetyl group, while the other is substituted by a 2,6-dimethylphenyl group.	2.31	1	alanine derivative; aromatic amide; carboxamide; ether; methyl ester
triazoles Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms.	2.82	3	1,2,3-triazole
prochloraz Mirage: a feldspathic porcelain that can be etched & bonded to the tooth. prochloraz : A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables.	3.18	1	amide fungicide; aromatic ether; conazole fungicide; imidazole fungicide; imidazoles; trichlorobenzene; ureas	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic
flusilazole flusilazole: structure given in first source. flusilazole : An organosilicon compound that is dimethylsilane in which the hydrogens attached to the silicon are replaced by p-fluorophenyl groups and a hydrogen attached to one of the methyl groups is replaced by a 1H-1,2,4-triazol-1-yl group. It is a broad-sepctrum fungicide used to protect a variety of crops.	3.18	1	conazole fungicide; monofluorobenzenes; organosilicon compound; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic
tebuconazole Lynx: A genus in the family FELIDAE comprising felines with long legs, ear tufts, and a short tail.. 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol : A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively.. tebuconazole : A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops.	3.65	2	monochlorobenzenes; tertiary alcohol; triazoles
cyproconazole cyproconazole: inhibits ergosterol biosynthesis in fungi. cyproconazole : A diastereoisomeric mixture composed of the enantiomeric pair (2R,3S)- and (2S,3R)-cyproconazole in ratio 1:1 with the enantiomeric pair (2R,3R)- and (2S,3S)-cyproconazole. A broad spectrum fungicide, it is used on cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases.. 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol : A tertiary alcohol that is butan-2-ol substituted by a 4-chlorophenyl group at position 2, a cyclopropyl group at position 3 and a 1H-1,2,4-triazol-1-yl group at position 1.	3.18	1	cyclopropanes; monochlorobenzenes; tertiary alcohol; triazoles
difenoconazole difenoconazole : A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms.	2.08	1	aromatic ether; conazole fungicide; cyclic ketal; dioxolane; triazole fungicide; triazoles	antifungal agrochemical; EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor; environmental contaminant; xenobiotic
cyprodinil cyprodinil: structure in first source. cyprodinil : A member of the class of aminopyrimidine that is N-phenylpyrimidin-2-amine carrying additional cyclopropyl and methyl substituents at positions 4 and 6 respectively. A broad spectrum fungicide used to control a range of pathogens including Tapesia yallundae, Botrytis spp., Alternaria spp. and Rhynchospium secalis. Whilst it is a recognised irritant no serious human health concerns have been identified. It is moderately toxic to birds as well as most aquatic organisms and earthworms, but it is not considered toxic to honeybees.	4.12	4	aminopyrimidine; anilinopyrimidine fungicide; cyclopropanes; secondary amino compound	antifungal agrochemical; aryl hydrocarbon receptor agonist; environmental contaminant; xenobiotic
fludioxonil fludioxonil: structure in first source. fludioxonil : A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria.	2.76	3	benzodioxoles; nitrile; organofluorine compound; pyrroles	androgen antagonist; antifungal agrochemical; estrogen receptor agonist
pyrimethanil pyrimethanil: structure in first source. pyrimethanil : A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine.	4.05	4	aminopyrimidine; anilinopyrimidine fungicide; secondary amino compound	antifungal agrochemical; aryl hydrocarbon receptor agonist; environmental contaminant; xenobiotic
triflumizol triflumizol: structure given in first source. triflumizole : A carboxamidine resulting from the formal condensation of the amino group of 4-chloro-2-(trifluoromethyl)aniline with the oxygen of the acetyl group of N-(propoxyacetyl)imidazole. A sterol demethylation inhibitor, it is used as a fungicide for the control of powdery mildew, scab and other diseases on a variety of crops.	3.18	1
fenpropimorph [no description available]	4.25	5	alkylbenzene
fulvestrant Fulvestrant: An estradiol derivative and estrogen receptor antagonist that is used for the treatment of estrogen receptor-positive, locally advanced or metastatic breast cancer.. fulvestrant : A 3-hydroxy steroid that is 17beta-estradiol in which the 7alpha hydrogen has been replaced by a nonyl group in which one of the hydrogens of the terminal methyl has been replaced by a (4,4,5,5,5-pentafluoropentyl)sulfinyl group. An estrogen receptor antagonist, it is used in the treatment of breast cancer.	2.11	1	17beta-hydroxy steroid; 3-hydroxy steroid; organofluorine compound; sulfoxide	antineoplastic agent; estrogen antagonist; estrogen receptor antagonist
spirodiclofen spirodiclofen: an acaricide	2.31	1	dichlorobenzene; gamma-lactone; organochlorine acaricide; oxaspiro compound
2-chloro-n-(4-chlorobiphenyl-2-yl)nicotinamide boscalid : A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including Botrytis spp., Alternaria spp. and Sclerotinia spp. for use on a wide range of crops including fruit, vegetables and ornamentals.	3.58	2	anilide fungicide; biphenyls; monochlorobenzenes; pyridinecarboxamide	antifungal agrochemical; EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor; environmental contaminant; xenobiotic
famoxadone famoxadone: strobilurin analogue; structure in first source. famoxadone : A racemate composed of equimolar amounts of (R)- and (S)-famoxadone. It prevents spore germination and mycelial growth of sensitive fungi, and is used in agriculture for the control of various fungal diseases. Only the (S)- enantiomer is active.. 5-methyl-5-(4-phenoxyphenyl)-3-(phenylamino)-1,3-oxazolidine-2,4-dione : A member of the class of oxazolidinones that is 1,3-oxazolidine-2,4-dione in which the hydrogen attached to the nitrogen is substituted by a phenylamino group and the hydrogens at position 5 are substituted by methyl and 4-phenoxyphenyl groups.	2.74	3	aromatic ether; carbohydrazide; oxazolidinone
lanosterol [no description available]	2.08	1	14alpha-methyl steroid; 3beta-sterol; tetracyclic triterpenoid	bacterial metabolite; human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite
glycogen glycogen : A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues.	2.02	1
ergosterol [no description available]	3	4	3beta-hydroxy-Delta(5)-steroid; 3beta-sterol; ergostanoid; phytosterols	fungal metabolite; Saccharomyces cerevisiae metabolite
streptothricins Streptothricins: A group of antibiotic aminoglycosides differing only in the number of repeating residues in the peptide side chain. They are produced by Streptomyces and Actinomyces and may have broad spectrum antimicrobial and some antiviral properties.. streptothricin : An N-glycosyl compound consisting of 2-amino-4-O-carbamoyl-2-deoxy-N-[(3aS,7R,7aS)-7-hydroxy-4-oxooctahydro-2H-imidazo[4,5-c]pyridin-2-ylidene]-beta-D-gulopyranosylamine in which the amino group at position 2 of the gulopyranosyl moiety is acylated by a peptide unit made up of between 1 and 7 N(epsilon)-linked units of beta-lysine.	2.15	1
terbinafine [no description available]	3.18	1	acetylenic compound; allylamine antifungal drug; enyne; naphthalenes; tertiary amine	EC 1.14.13.132 (squalene monooxygenase) inhibitor; P450 inhibitor; sterol biosynthesis inhibitor
thiophanate Thiophanate: Nematocide used in livestock; also has fungicidal properties.. thiophanate : A member of the class of thioureas that is the diethyl ester of (1,2-phenylenedicarbamothioyl)biscarbamic acid. A fungicide effective against a broad spectrum of diseases in fruit, vegetables, turf and other crops including eyespot, scab, powdery mildew and grey mould.	2.17	1	benzimidazole precursor fungicide; carbamate ester; carbamate fungicide; thioureas	antifungal drug
azoxystrobin azoxystrobin: a methoxyacrylate analog; a strobilurin fungicide; structure given in first source. azoxystrobin : An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture.	2.02	1	aryloxypyrimidine; enoate ester; enol ether; methoxyacrylate strobilurin antifungal agent; methyl ester; nitrile	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; quinone outside inhibitor; xenobiotic
quinoxyfen quinoxyfen: structure in first source. quinoxyfen : A member of the class of quinolines carrying two chloro substituents at positions 5 and 7 together with a 4-fluorophenoxy substituent at position 4. A fungicide used mainly to control powdery mildew in cereals.	2.05	1	aromatic ether; monofluorobenzenes; organochlorine compound; quinolines	antifungal agrochemical
phosphorus Phosphorus: A non-metal element that has the atomic symbol P, atomic number 15, and atomic weight 31. It is an essential element that takes part in a broad variety of biochemical reactions.	2.06	1	monoatomic phosphorus; nonmetal atom; pnictogen	macronutrient
boron Boron: A trace element with the atomic symbol B, atomic number 5, and atomic weight [10.806; 10.821]. Boron-10, an isotope of boron, is used as a neutron absorber in BORON NEUTRON CAPTURE THERAPY.	2.6	1	boron group element atom; metalloid atom; nonmetal atom	micronutrient
kresoxim-methyl kresoxim-methyl: strobilurin analogue; an industrial fungicide. kresoxim-methyl : A carboxylic ester that is the methyl ester of (2E)-(methoxyimino){2-[(2-methylphenoxy)methyl]phenyl}acetic acid. A fungicide for the control of scab on apples and pears and other fungal diseases on a wide range of crops.	2.05	1	aromatic ether; methoxyiminoacetate strobilurin antifungal agent; methyl ester; oxime O-ether	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic
pyrachlostrobin pyraclostrobin : A carbamate ester that is the methyl ester of [2-({[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy}methyl)phenyl]methoxycarbamic acid. A fungicide used to control major plant pathogens including Septoria tritici, Puccinia spp. and Pyrenophora teres.	2.52	2	aromatic ether; carbamate ester; carbanilate fungicide; methoxycarbanilate strobilurin antifungal agent; monochlorobenzenes; pyrazoles	antifungal agrochemical; environmental contaminant; mitochondrial cytochrome-bc1 complex inhibitor; xenobiotic
hygromycin a hygromycin A: a cinnamide derivative produced by Streptomyces hygroscopicus; structure differs from HYGROMYCIN B	2.15	1	hydroxycinnamic acid	metabolite
metrafenone metrafenone: an industrial fungicide; structure in first source. metrafenone : A member of the class of benzophenones that is benzophenone in which one of the phenyl groups is substituted by methoxy groups at positions 2, 3, and 4 and by a methyl group at position 6, while the other is substituted at positions 2, 3, and 6 by methyl, bromine, and methoxy groups, respectively. A fungicide with protectant and curative properties, it is used for the control of powdery mildew in cereals and grape vines.	3.18	1	aromatic ether; aryl phenyl ketone fungicide; benzophenones; organobromine compound	antifungal agrochemical
prothioconazole prothioconazole: a fungicide. prothioconazole : A racemate comprising equal amounts of (R)- and (S)-prothioconazole. A fungicide for use both as a seed treatment and foliar spray to treat a variety of diseases in cereals.. 2-[2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl]-1,2-dihydro-1,2,4-triazole-3-thione : A member of the class of triazoles that is 1,2,4-triazole-3-thione substituted at position 2 by a 2-(1-chlorocyclopropyl)-3-(2-chlorophenyl)-2-hydroxypropyl group.	3.18	1	cyclopropanes; monochlorobenzenes; tertiary alcohol; thiocarbonyl compound; triazoles
ebericol ebericol: RN given refers to the unlabeled compound. eburicol : A tetracyclic triterpenoid that is 24,25-dihydrolanosterol carrying an additional methylene substituent at position 24. A natural product found in Taiwanofungus camphoratus.	2.08	1	14alpha-methyl steroid; 3beta-sterol; tetracyclic triterpenoid	fungal metabolite
penthiopyrad penthiopyrad: a fungicide. penthiopyrad : A racemate comprising equimolar amounts of (R)- and (S)-penthiopyrad. Used to control rust and Rhizoctonia diseases and also shows activity against grey mould, powdery mildew and apple scab.. 1-methyl-N-[2-(4-methylpentan-2-yl)-3-thienyl]-3-(trifluoromethyl)pyrazole-4-carboxamide : An aromatic amide obtained by formal condensation of the carboxy group of 1-methyl-3-(trifluoromethyl)pyrazole-4-carboxylic acid with the amino group of 2-(4-methylpentan-2-yl)thiophen-3-amine.	3.62	2	aromatic amide; organofluorine compound; pyrazoles; thiophenes
phytosterols Phytosterols: A class of organic compounds known as sterols or STEROIDS derived from plants.. phytosterols : Sterols similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond.	2.42	2
chlorophyll a Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.	2.05	1	chlorophyll; methyl ester	cofactor
hygromycin b [no description available]	2.15	1
trifloxystrobin trifloxystrobin : The methyl ester of (2E)-(methoxyimino)[2-({[(E)-{1-[3-(trifluoromethyl)phenyl]ethylidene}amino]oxy}methyl)phenyl]acetic acid. A foliar applied fungicide for cereals which is particularly active against Ascomycetes, Deuteromycetes and Oomycetes	2.44	2
clay Clay: A naturally-occurring rock or soil constituent characterized by particles with a diameter of less than 0.005 mm. It is composed primarily of hydrous aluminum silicates, trace amounts of metal OXIDES, and organic matter.	2.05	1
pyrethrins [no description available]	2.15	1
cyclin d1 Cyclin D1: Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.	2.11	1
pheophytin a pheophytin a: structure given in first source; RN given refers to (3S-(3alpha(2E,7S,11S),4beta,21beta))-isomer	2.05	1
metallothionein Metallothionein: A low-molecular-weight (approx. 10 kD) protein occurring in the cytoplasm of kidney cortex and liver. It is rich in cysteinyl residues and contains no aromatic amino acids. Metallothionein shows high affinity for bivalent heavy metals.	2.02	1

Condition	Relationship Strength	Studies
Breast Cancer [description not available]	2.31	1
Breast Neoplasms Tumors or cancer of the human BREAST.	2.31	1
Cancer of Ovary [description not available]	2.11	1
Ovarian Neoplasms Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.	2.11	1

n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide

Description

Cross-References

Synonyms (49)

Roles (3)

Drug Classes (5)

Protein Targets (18)

Potency Measurements

Biological Processes (124)

Molecular Functions (34)

Ceullar Components (20)

Bioassays (121)

Research

Studies (47)

Market Indicators

Research Demand Index: 10.71

Study Types

n-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide

Description

Cross-References

Synonyms (49)

Roles (3)

Drug Classes (5)

Protein Targets (18)

Potency Measurements

Biological Processes (124)

Molecular Functions (34)

Ceullar Components (20)

Bioassays (121)

Research

Studies (47)

Market Indicators

Research Demand Index: 10.71

Study Types

Related Drugs (67)

Related Conditions (4)