Page last updated: 2024-12-07

oryzemate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

Oryzemate is a natural product with a unique chemical structure containing a spiro-fused pyranopyrone ring system. It was isolated from rice bran and exhibits a range of biological activities, including anti-inflammatory, antioxidant, and antitumor properties. Oryzemate's potential as a therapeutic agent has sparked research interest due to its promising pharmacological effects. Studies have investigated its synthesis, mechanisms of action, and potential applications in the treatment of various diseases.'

oryzemate: induces disease resistance against rice blast fungus in rice; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

probenazole : A member of the class of 1,2-benzothiazoles that is 1,2-benzothiazole 1,1-dioxide substituted at position 3 by an allyloxy group. A fungicide used to control rice blast. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID91587
CHEMBL ID2287211
CHEBI ID81778
SCHEMBL ID23516
MeSH IDM0260108

Synonyms (37)

Synonym
oryzaemate
po-20
1,2-benzisothiazole, 3-(2-propenyloxy)-, 1,1-dioxide
probenazole
oryzemate
brn 1214464
3-(allyloxy)-1,2-benzisothiazole 1,1-dioxide
1,2-benzisothiazole, 3-(allyloxy)-, 1,1-dioxide
3-(2-propenyloxy)-1,2-benzisothiazole 1,1-dioxide
27605-76-1
3-prop-2-enoxy-1,2-benzothiazole 1,1-dioxide
C18483
AKOS015917662
unii-fgb5blx49h
fgb5blx49h ,
FT-0630535
SCHEMBL23516
chebi:81778 ,
probenazol
CHEMBL2287211
3-allyloxy-1,2-benz[d]isothiazole 1,1-dioxide
3-(allyloxy)-1,2-benzothiazole 1,1-dioxide
3-(2-propen-1-yloxy)-1,2-benzisothiazole 1,1-dioxide
DTXSID7058048
3-(allyloxy)benzo[d]isothiazole 1,1-dioxide
WHHIPMZEDGBUCC-UHFFFAOYSA-N
probenazole, pestanal(r), analytical standard
mfcd00274602
AS-16095
Q11336142
D95681
1,2-benzisothiazole, 3-(2-propen-1-yloxy)-, 1,1-dioxide
CBA60576
po20
probenazole [mi]
3-allyloxy-1,2-benzothiazole 1,1-dioxide
P2802

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" Dose-response and time course experiments revealed a similar pattern of transcript accumulation and lipoxygenase activity in BTH-treated rice leaves."( Characterization of RCI-1, a chloroplastic rice lipoxygenase whose synthesis is induced by chemical plant resistance activators.
Dudler, R; Schaffrath, U; Zabbai, F, 2000
)
0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (2)

RoleDescription
plant activatorAny compound that protects plants by activating their defence mechanisms.
antifungal agrochemicalAny substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (4)

ClassDescription
1,2-benzisothiazoleA benzothiazole consisting of a benzene ring fused to an isothiazole.
aromatic etherAny ether in which the oxygen is attached to at least one aryl substituent.
sulfoneAn organosulfur compound having the structure RS(=O)2R (R =/= H).
benzothiazole fungicideCompounds that contain a benzothiazole moiety as a key feature of their structure and which have been used as fungicides.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (25)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's2 (8.00)18.2507
2000's17 (68.00)29.6817
2010's3 (12.00)24.3611
2020's3 (12.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies1 (4.00%)4.05%
Observational0 (0.00%)0.25%
Other24 (96.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]