A cyclin-dependent kinase 8 that is encoded in the genome of mouse. [OMA:Q8R3L8, PRO:DNx]
EC 2.7.11.22;
EC 2.7.11.23;
Cell division protein kinase 8;
Mediator complex subunit CDK8;
Mediator of RNA polymerase II transcription subunit CDK8
| Timeframe | Studies on this Protein(%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Drug | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Publication(s) |
|---|---|---|---|---|---|
| 2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile | Mus musculus (house mouse) | EC50 | 1.4000 | 1 | 1 |
| CCT251545 | Mus musculus (house mouse) | EC50 | 0.0200 | 1 | 0 |