Page last updated: 2024-09-28

Myxosarcoma

A sarcoma, usually a liposarcoma or malignant fibrous histiocytoma, with an abundant component of myxoid tissue resembling primitive mesenchyme containing connective tissue mucin. (Stedman, 25th ed)

Synonyms(1)

Synonym
Myxosarcoma

Research

Studies (40)

TimeframeStudies, This Condition (%)All Conditions %
pre-199025 (62.50)23.3326
1990's1 (2.50)12.5806
2000's4 (10.00)18.1394
2010's9 (22.50)28.8240
2020's1 (2.50)9.53
DrugIndicatedRelationship StrengthStudiesTrials
pyruvic acid0low10
3-methylcholanthrene0low10
chlorambucil0low10
gossypol0low10
ifosfamide0low10
2-propanol0low20
loperamide0low10
thiotepa0low10
hydroxyproline0low10
isoprene0low10
thiazoles0low20
cadmium0low10
trolamine salicylate0low10
fluorodeoxyglucose f180low10
imatinib mesylate0low10
methotrexate0low30
carboplatin0low10
dactinomycin0low20
melphalan0low30
strontium0low10
radium0low10
mart-1 antigen0low10
jaw0low10
mobic0low20
cyclin d10low20
hyaluronoglucosaminidase0low20
levoleucovorin0low10

Protein Targets (382)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
hypoxia-inducible factor 1 alpha subunit5005
RAR-related orphan receptor gamma110011
GLI family zinc finger 3100010
AR protein130013
aldehyde dehydrogenase 1 family, member A18008
retinoic acid nuclear receptor alpha variant 1120012
retinoid X nuclear receptor alpha100010
estrogen nuclear receptor alpha130013
peroxisome proliferator-activated receptor delta100010
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a110011
activating transcription factor 65005
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x8008
thyroid hormone receptor beta isoform a4004
heat shock protein beta-14004
nuclear factor erythroid 2-related factor 2 isoform 1120012
lamin isoform A-delta107007
Voltage-dependent calcium channel gamma-2 subunit8008
Glutamate receptor 28008
Luciferase6006
pregnane X receptor2002
phosphopantetheinyl transferase5005
SMAD family member 25005
SMAD family member 35005
TDP1 protein100010
Microtubule-associated protein tau5005
caspase 7, apoptosis-related cysteine protease6006
nuclear receptor subfamily 1, group I, member 3100010
estrogen-related nuclear receptor alpha110011
farnesoid X nuclear receptor9009
pregnane X nuclear receptor8008
peroxisome proliferator activated receptor gamma8008
caspase-36006
euchromatic histone-lysine N-methyltransferase 28008
aryl hydrocarbon receptor6006
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a4004
Cellular tumor antigen p539009
Cytochrome P450 1A20101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Aldo-keto reductase family 1 member B10202
Adenosine receptor A30202
Alpha-1B adrenergic receptor0202
Acetylcholinesterase0101
Sodium-dependent noradrenaline transporter 0202
Aryl hydrocarbon receptor0011
Alpha-1A adrenergic receptor0202
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE5005
Chain A, TYROSYL-DNA PHOSPHODIESTERASE5005
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
acetylcholinesterase4004
estrogen receptor 2 (ER beta)7007
G6006
cytochrome P450 2D65005
vitamin D3 receptor isoform VDRA6006
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
DNA polymerase kappa isoform 13003
histone acetyltransferase KAT2A isoform 13003
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 6006
Inositol hexakisphosphate kinase 16006
cytochrome P450 2C9, partial6006
ATP-dependent phosphofructokinase5005
interleukin 83003
thioredoxin reductase6006
NFKB1 protein, partial1001
GALC protein3003
GLS protein4004
Thrombopoietin2002
thioredoxin glutathione reductase3003
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
thyroid stimulating hormone receptor3003
EWS/FLI fusion protein7007
bromodomain adjacent to zinc finger domain 2B2002
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
Bloom syndrome protein isoform 14004
peripheral myelin protein 22 isoform 11001
chromobox protein homolog 15005
potassium voltage-gated channel subfamily H member 2 isoform d3003
thyroid hormone receptor beta isoform 2100010
FAD-linked sulfhydryl oxidase ALR0001
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
geminin8008
peripheral myelin protein 225005
survival motor neuron protein isoform d7007
muscleblind-like protein 1 isoform 13003
muscarinic acetylcholine receptor M12002
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40607
Carbonic anhydrase 120101
Bile salt export pump0707
Carbonic anhydrase 10101
Carbonic anhydrase 20112
Cytochrome P450 2D60202
Nuclear receptor ROR-gamma3003
Spike glycoprotein6017
Carbonic anhydrase 90101
Canalicular multispecific organic anion transporter 10505
ATPase family AAA domain-containing protein 58008
Ataxin-28008
Solute carrier organic anion transporter family member 1B30405
Chain A, HADH2 protein3003
Chain B, HADH2 protein3003
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain2002
Chain A, Cruzipain2002
15-lipoxygenase, partial5005
USP1 protein, partial4004
progesterone receptor8008
cytochrome P450 family 3 subfamily A polypeptide 47007
glucocorticoid receptor [Homo sapiens]7007
RAD510101
Caspase-73003
caspase-33003
huntingtin isoform 23003
nuclear receptor ROR-gamma isoform 13003
cytochrome P450 3A4 isoform 15005
caspase-1 isoform alpha precursor3003
Gamma-aminobutyric acid receptor subunit pi5005
ATP-dependent translocase ABCB10103
Gamma-aminobutyric acid receptor subunit beta-15005
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Gamma-aminobutyric acid receptor subunit alpha-65005
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Caspase-73003
Gamma-aminobutyric acid receptor subunit alpha-15005
Growth factor receptor-bound protein 20101
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0101
GABA theta subunit5005
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Gamma-aminobutyric acid receptor subunit epsilon5005
Chain A, 2-oxoglutarate Oxygenase2002
Mcl-10101
ATAD5 protein, partial4004
Fumarate hydratase2002
PPM1D protein2002
Estrogen receptor 10101
Smad32002
DNA polymerase III, partial1001
PINK11001
regulator of G-protein signaling 42002
polyprotein2002
67.9K protein2002
Parkin1001
arylsulfatase A2002
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
cytochrome P450 2D6 isoform 12002
lysosomal alpha-glucosidase preproprotein1001
galactokinase1001
hexokinase-4 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a4004
polyunsaturated fatty acid lipoxygenase ALOX123003
cytochrome P450 2C19 precursor1001
cytochrome P450 2C9 precursor1001
D(1A) dopamine receptor1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
atrial natriuretic peptide receptor 1 precursor1001
glucokinase regulatory protein1001
DNA polymerase beta2002
mitogen-activated protein kinase 11001
atrial natriuretic peptide receptor 2 precursor2002
nuclear factor NF-kappa-B p105 subunit isoform 11001
flap endonuclease 12002
ubiquitin carboxyl-terminal hydrolase 2 isoform a2002
ras-related protein Rab-9A2002
eukaryotic translation initiation factor 4 gamma 1 isoform 40101
serine/threonine-protein kinase mTOR isoform 13003
tyrosine-protein kinase Yes1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase iota isoform a (long)4004
eukaryotic translation initiation factor 4E isoform 10101
M-phase phosphoprotein 82002
4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase1001
lethal factor (plasmid)1001
neuropeptide S receptor isoform A1001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Prolyl endopeptidase0101
L-lactate dehydrogenase A chain0101
Malate dehydrogenase, mitochondrial0101
Beta-lactamase0101
Integrin beta-33003
L-lactate dehydrogenase B chain0101
Muscarinic acetylcholine receptor M10101
Muscarinic acetylcholine receptor M30101
Muscarinic acetylcholine receptor M40101
Integrin alpha-IIb3003
Muscarinic acetylcholine receptor M50101
Apoptosis regulator Bcl-20213
Muscarinic acetylcholine receptor M20101
Solute carrier family 2, facilitated glucose transporter member 10101
Malate dehydrogenase, cytoplasmic0101
Aldo-keto reductase family 1 member B10101
L-lactate dehydrogenase B chain0101
DNA-3-methyladenine glycosylase0101
Caspase-11102
Alpha-synuclein1001
DNA repair protein RAD52 homolog0101
Histamine H2 receptor2003
D(1A) dopamine receptor2002
5-hydroxytryptamine receptor 70202
Kinesin-like protein KIF110101
BH3-interacting domain death agonist0101
Disintegrin and metalloproteinase domain-containing protein 172002
Type 1 InsP3 receptor isoform S2 1001
Inositol monophosphatase 12002
E3 ubiquitin-protein ligase Mdm20101
Bcl-2-like protein 10213
Induced myeloid leukemia cell differentiation protein Mcl-10213
Peroxisome proliferator-activated receptor alpha1001
L-lactate dehydrogenase0101
Aspartyl/asparaginyl beta-hydroxylase0101
L-lactate dehydrogenase0101
L-lactate dehydrogenase B chain0101
L-lactate dehydrogenase0101
Bcl-2-like protein 20101
Bcl2-associated agonist of cell death 0101
Inosine-5'-monophosphate dehydrogenase 0101
Histamine H3 receptor1001
Solute carrier organic anion transporter family member 1B10202
phosphoglycerate kinase1001
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Neutral amino acid transporter A0101
Asc-type amino acid transporter 10101
Neutral amino acid transporter B(0)0101
Proton-coupled amino acid transporter 10101
Amino acid transporter0101
Chain A, Beta-lactamase2002
Serum paraoxonase/arylesterase 10101
glp-1 receptor, partial2002
IDH12002
thyroid stimulating hormone receptor2002
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
DNA repair protein RAD52 homolog isoform a0001
Tyrosine-protein kinase ABL10123
Cytochrome P450 3A40001
Cytochrome P450 2C80001
Mast/stem cell growth factor receptor Kit0112
Breakpoint cluster region protein0011
Platelet-derived growth factor receptor alpha0112
Cytochrome P450 3A50001
Chymotrypsinogen A0101
Spike glycoprotein0011
Replicase polyprotein 1ab0011
Menin0101
Cocaine esterase0202
Solute carrier family 22 member 1 0101
Transmembrane protease serine 20011
Beta-2 adrenergic receptor0202
Procathepsin L0011
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0112
D(2) dopamine receptor0101
D(4) dopamine receptor0101
Histamine H2 receptor0202
Sodium-dependent serotonin transporter0202
Delta-type opioid receptor0202
Mu-type opioid receptor0202
Mu-type opioid receptor0202
D(3) dopamine receptor0202
Delta-type opioid receptor0213
Kappa-type opioid receptor0202
Nociceptin receptor0101
5-hydroxytryptamine receptor 2B0202
Calmodulin 0112
Mu-type opioid receptor0011
Angiopoietin-1 receptor0011
Potassium voltage-gated channel subfamily H member 20101
Sodium channel protein type 5 subunit alpha0101
Sigma non-opioid intracellular receptor 10202
Angiotensin-converting enzyme 2 0011
HLA class I histocompatibility antigen, A alpha chain 0101
5-hydroxytryptamine receptor 2C0203
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2B0101
Gastrin/cholecystokinin type B receptor0101
glucocerebrosidase1001
importin subunit beta-1 isoform 12002
snurportin-12002
TAR DNA-binding protein 433003
Large neutral amino acids transporter small subunit 1 0101
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
acid sphingomyelinase1001
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0101
alpha-galactosidase2002
Thymidylate synthase 0101
nuclear factor erythroid 2-related factor 2 isoform 21001
transcriptional regulator ERG isoform 31001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
DNA polymerase eta isoform 11001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase 0101
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Thymidylate synthase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Thymidylate synthase0202
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Dihydrofolate reductase0224
Glucose-6-phosphate 1-dehydrogenase0202
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Multidrug resistance-associated protein 1 0001
Kappa-type opioid receptor0101
Reduced folate transporter0202
Folylpolyglutamate synthase, mitochondrial0103
6-phosphogluconate dehydrogenase, decarboxylating0202
Solute carrier organic anion transporter family member 1A30001
Dihydrofolate reductase0101
Pteridine reductase 10101
Folylpolyglutamate synthase, mitochondrial0103
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200202
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60202
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Multidrug resistance associated protein0102
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
Broad substrate specificity ATP-binding cassette transporter ABCG20001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Glutathione reductase, mitochondrial0101
Prostaglandin G/H synthase 10101
Prostaglandin G/H synthase 20101
Prostaglandin G/H synthase 20101
Monocarboxylate transporter 40001
Monocarboxylate transporter 20001
Monocarboxylate transporter 10001
C-terminal-binding protein 20101
Monocarboxylate transporter 20101
Prolyl 4-hydroxylase0101
Solute carrier organic anion transporter family member 2A10101
Alpha-ketoglutarate-dependent dioxygenase FTO0101
hemoglobin subunit beta1001
serine/threonine-protein kinase PLK11001
Cytochrome P450 2B10101
Cytochrome P450 2B60101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]