Page last updated: 2024-09-28

Myosarcoma

A general term for a malignant neoplasm derived from muscular tissue. (Stedman, 25th ed)

Synonyms(1)

Synonym
Myosarcoma

Research

Studies (39)

TimeframeStudies, This Condition (%)All Conditions %
pre-199028 (71.79)23.3326
1990's1 (2.56)12.5806
2000's8 (20.51)18.1394
2010's2 (5.13)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
toluene0low10
3-methylcholanthrene0low50
chlorambucil0low10
chloroquine0low20
dapi0low10
ifosfamide0low10
mechlorethamine0low10
nalidixic acid0low10
mitomycin0low10
edetic acid0low10
methionine0low10
phenylalanine0low10
cycloheximide0low10
triaziquone0low10
acetylene0low10
platinum0low10
daunorubicin0low20
fluorodeoxyglucose f180low10
cobalt0low20
methotrexate0low20
carboplatin0low10
dactinomycin0low30
melphalan0low10
bromochloroacetic acid0low10
cobaltous chloride0low10
selenium0low10
peplomycin0low20
transforming growth factor beta0low10
folic acid0low10

Protein Targets (408)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Luciferase6006
pregnane X receptor4004
phosphopantetheinyl transferase5005
RAR-related orphan receptor gamma120012
SMAD family member 23003
SMAD family member 33003
TDP1 protein120012
Microtubule-associated protein tau6006
AR protein150015
caspase 7, apoptosis-related cysteine protease6006
aldehyde dehydrogenase 1 family, member A19009
nuclear receptor subfamily 1, group I, member 3120012
retinoic acid nuclear receptor alpha variant 1130013
estrogen-related nuclear receptor alpha140014
farnesoid X nuclear receptor8008
pregnane X nuclear receptor8008
estrogen nuclear receptor alpha160016
peroxisome proliferator-activated receptor delta110011
peroxisome proliferator activated receptor gamma9009
caspase-36006
euchromatic histone-lysine N-methyltransferase 2110011
aryl hydrocarbon receptor8008
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a100010
activating transcription factor 69009
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
thyroid hormone receptor beta isoform a7007
heat shock protein beta-13003
nuclear factor erythroid 2-related factor 2 isoform 1130013
Voltage-dependent calcium channel gamma-2 subunit9009
Cellular tumor antigen p53140014
Cytochrome P450 1A20101
Tyrosine-protein kinase Lck0101
Tyrosine-protein kinase Fyn0101
Aldo-keto reductase family 1 member B10202
Adenosine receptor A30202
Alpha-1B adrenergic receptor0202
Glutamate receptor 29009
Acetylcholinesterase0202
Sodium-dependent noradrenaline transporter 0202
Aryl hydrocarbon receptor0011
Alpha-1A adrenergic receptor0202
Chain A, Beta-lactamase2002
Chain A, HADH2 protein5005
Chain B, HADH2 protein5005
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, Cruzipain2002
acid sphingomyelinase3003
hypoxia-inducible factor 1 alpha subunit6006
ATAD5 protein, partial3003
GLI family zinc finger 3100010
apical membrane antigen 1, AMA11001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)4004
thyroid stimulating hormone receptor4004
estrogen receptor 2 (ER beta)9009
progesterone receptor9009
glucocorticoid receptor [Homo sapiens]7007
retinoid X nuclear receptor alpha120012
glucocerebrosidase3003
bromodomain adjacent to zinc finger domain 2B3003
P532002
vitamin D (1,25- dihydroxyvitamin D3) receptor120012
IDH13003
thyroid stimulating hormone receptor4004
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Caspase-75005
serine-protein kinase ATM isoform a1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 13003
chromobox protein homolog 15005
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
caspase-35005
thyroid hormone receptor beta isoform 2100010
mitogen-activated protein kinase 12002
nuclear factor NF-kappa-B p105 subunit isoform 12002
ras-related protein Rab-9A2002
urokinase-type plasminogen activator precursor5005
plasminogen precursor5005
urokinase plasminogen activator surface receptor precursor5005
nuclear receptor ROR-gamma isoform 16006
lethal(3)malignant brain tumor-like protein 1 isoform I1001
geminin7007
cytochrome P450 3A4 isoform 15005
caspase-1 isoform alpha precursor3003
Gamma-aminobutyric acid receptor subunit pi5005
Gamma-aminobutyric acid receptor subunit beta-15005
Gamma-aminobutyric acid receptor subunit delta5005
Gamma-aminobutyric acid receptor subunit gamma-25005
Gamma-aminobutyric acid receptor subunit alpha-55005
Gamma-aminobutyric acid receptor subunit alpha-35005
Gamma-aminobutyric acid receptor subunit gamma-15005
Gamma-aminobutyric acid receptor subunit alpha-25005
Gamma-aminobutyric acid receptor subunit alpha-45005
Gamma-aminobutyric acid receptor subunit gamma-35005
Gamma-aminobutyric acid receptor subunit alpha-65005
Nuclear receptor ROR-gamma6006
Caspase-73003
Gamma-aminobutyric acid receptor subunit alpha-15005
Gamma-aminobutyric acid receptor subunit beta-35005
Gamma-aminobutyric acid receptor subunit beta-25005
GABA theta subunit5005
ATPase family AAA domain-containing protein 58008
Ataxin-29009
Gamma-aminobutyric acid receptor subunit epsilon5005
Histone H2A.x9009
histone deacetylase 9 isoform 31001
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE8008
Chain A, TYROSYL-DNA PHOSPHODIESTERASE6006
Chain A, Putative fructose-1,6-bisphosphate aldolase4004
acetylcholinesterase2002
G2002
cytochrome P450 2D64004
vitamin D3 receptor isoform VDRA5005
histone-lysine N-methyltransferase 2A isoform 2 precursor3003
DNA polymerase kappa isoform 13003
histone acetyltransferase KAT2A isoform 13003
Interferon beta7007
HLA class I histocompatibility antigen, B alpha chain 2002
Inositol hexakisphosphate kinase 12002
cytochrome P450 2C9, partial2002
ATP-dependent phosphofructokinase4004
interleukin 84004
thioredoxin reductase4004
NFKB1 protein, partial1001
GALC protein2002
GLS protein2002
Thrombopoietin1001
thioredoxin glutathione reductase2002
EWS/FLI fusion protein7007
Bloom syndrome protein isoform 14004
peripheral myelin protein 22 isoform 11001
potassium voltage-gated channel subfamily H member 2 isoform d2002
FAD-linked sulfhydryl oxidase ALR0001
peripheral myelin protein 227007
survival motor neuron protein isoform d5005
muscleblind-like protein 1 isoform 13003
muscarinic acetylcholine receptor M11001
lamin isoform A-delta105005
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40608
Carbonic anhydrase 120102
Bile salt export pump0808
Carbonic anhydrase 10102
Carbonic anhydrase 20113
Cytochrome P450 2D60101
Spike glycoprotein6129
Carbonic anhydrase 90102
Canalicular multispecific organic anion transporter 10707
Solute carrier organic anion transporter family member 1B30203
PPM1D protein4004
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
Spike glycoprotein0123
Replicase polyprotein 1ab0123
glucose-6-phosphate 1-dehydrogenase isoform b0101
flap endonuclease 12002
Transmembrane protease serine 20123
Dihydrofolate reductase 0202
DNA ligase0101
Riboflavin-binding protein0011
Major prion protein0011
Amyloid-beta precursor protein0202
Histidine-rich protein PFHRP-II0102
Procathepsin L0123
Muscarinic acetylcholine receptor M20101
Muscarinic acetylcholine receptor M40101
Cytochrome P450 3A40101
Muscarinic acetylcholine receptor M50101
Alpha-2A adrenergic receptor0101
Replicase polyprotein 1a0123
Replicase polyprotein 1ab0123
Replicase polyprotein 1ab0123
Spike glycoprotein0101
Replicase polyprotein 1ab0123
Muscarinic acetylcholine receptor M10101
Ribosyldihydronicotinamide dehydrogenase [quinone]0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
DNA ligase 10101
Muscarinic acetylcholine receptor M30101
Serine/threonine-protein kinase mTOR0101
Nuclear receptor subfamily 4 group A member 20011
Beta-secretase 10101
Calcium-dependent protein kinase 10011
MO15-related protein kinase Pfmrk 0101
DNA ligase A0101
Potassium voltage-gated channel subfamily H member 20202
Sigma intracellular receptor 20101
Phosphoethanolamine N-methyltransferase0101
Sigma non-opioid intracellular receptor 10101
Angiotensin-converting enzyme 2 0123
Cysteine proteinase falcipain 2a 0101
Cysteine proteinase falcipain 2a 0101
glp-1 receptor, partial3003
Fumarate hydratase4004
USP1 protein, partial6006
Smad32002
polyprotein4004
67.9K protein3003
RPL19A0011
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a3003
nuclear factor erythroid 2-related factor 2 isoform 24004
heat shock protein HSP 90-alpha isoform 20001
transactivating tegument protein VP16 [Human herpesvirus 1]0202
COUP transcription factor 2 isoform a0101
lethal factor (plasmid)3003
Glucose transporter0101
Hexose transporter 1 0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Solute carrier family 2, facilitated glucose transporter member 10101
Alpha-synuclein2002
Eukaryotic initiation factor 4A-I0101
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
TAR DNA-binding protein 433003
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
Endothelial PAS domain-containing protein 10101
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain4004
15-lipoxygenase, partial4004
cytochrome P450 family 3 subfamily A polypeptide 44004
RAD510101
huntingtin isoform 22002
ATP-dependent translocase ABCB10103
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 10101
Growth factor receptor-bound protein 20101
Pantothenate synthetase0101
Discoidin domain-containing receptor 20101
Growth factor receptor-bound protein 2 0101
Reverse transcriptase/RNaseH 0202
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase0011
Prothrombin 0101
Glandular kallikrein0101
Cell division protein FtsZ0012
Chain A, Breast cancer type 1 susceptibility protein1001
Chain A, 2-oxoglutarate Oxygenase3003
runt-related transcription factor 1 isoform AML1b1001
core-binding factor subunit beta isoform 21001
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
Transthyretin0101
NADH-ubiquinone oxidoreductase chain 40001
Integrin beta-32002
72 kDa type IV collagenase0101
Integrin alpha-IIb2002
DNA topoisomerase 2-alpha0001
Carbonyl reductase [NADPH] 10001
Glutamate receptor 11001
Glutamate receptor 31001
Glutamate receptor 41001
Platelet-activating factor receptor1001
Multidrug resistance-associated protein 1 0204
Histamine H2 receptor2002
Inositol monophosphatase 11001
Histone deacetylase 10101
Histone deacetylase 80101
Histone deacetylase 60101
Broad substrate specificity ATP-binding cassette transporter ABCG20002
Eyes absent homolog 20101
Angiotensin-converting enzyme 0101
Metallo-beta-lactamase VIM-130101
Beta-lactamase 0101
Beta-lactamase 0101
Beta-lactamase VIM-1 0101
Chain A, Dihydrofolate reductase0011
alpha-galactosidase2002
lysosomal alpha-glucosidase preproprotein1001
DNA polymerase beta2002
Thymidylate synthase0404
Thymidylate synthase0303
Dihydrofolate reductase0235
Aldo-keto reductase family 1 member B10101
Folylpolyglutamate synthase, mitochondrial0104
Solute carrier organic anion transporter family member 1A30102
Folylpolyglutamate synthase, mitochondrial0104
Multidrug resistance associated protein0103
Serum paraoxonase/arylesterase 10101
importin subunit beta-1 isoform 13003
snurportin-13003
Large neutral amino acids transporter small subunit 1 0202
Chain A, Methionyl-tRNA synthetase0011
Chain A, Methionyl-tRNA synthetase0011
Chain A, Aminopeptidase0101
Chain A, Methionine aminopeptidase0101
S-ribosylhomocysteine lyase0101
Adenylate cyclase type 50001
S-adenosylmethionine synthase isoform type-10001
S-adenosylmethionine synthase isoform type-20001
Fatty acid synthase0101
Large neutral amino acids transporter small subunit 10203
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
Chain B, DIHYDROFOLATE REDUCTASE0011
dopamine D1 receptor1001
ClpP1001
Thymidylate synthase 0101
Thymidylate synthase 0101
polyunsaturated fatty acid lipoxygenase ALOX122002
transcriptional regulator ERG isoform 31001
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]0101
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 11001
DNA polymerase iota isoform a (long)2002
M-phase phosphoprotein 81001
nuclear receptor coactivator 3 isoform a0101
Toll-like receptor 40101
Fatty-acid amide hydrolase 10101
Bile salt export pump0101
ATP-binding cassette sub-family C member 30102
Dihydrofolate reductase0203
Dihydrofolate reductase0203
Dihydrofolate reductase0101
Dihydrofolate reductase0101
Dihydrofolate reductase0203
Thymidylate synthase0101
Tyrosine-protein kinase ABL10011
Bifunctional dihydrofolate reductase-thymidylate synthase0101
5-hydroxytryptamine receptor 2C0102
High mobility group protein B10011
Dihydrofolate reductase0101
Thymidylate synthase0101
Glucose-6-phosphate 1-dehydrogenase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Folate receptor beta0101
5-hydroxytryptamine receptor 2A0101
Cytochrome P450 11B1, mitochondrial 0101
Folate receptor alpha0101
Dihydrofolate reductase0202
Histidine decarboxylase0101
Trifunctional purine biosynthetic protein adenosine-30101
Cyclin-dependent kinase 20011
Bifunctional purine biosynthesis protein ATIC0202
Delta-type opioid receptor0101
Mu-type opioid receptor0101
Kappa-type opioid receptor0101
Reduced folate transporter0202
6-phosphogluconate dehydrogenase, decarboxylating0101
Dihydrofolate reductase0101
Pteridine reductase 10101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Bifunctional dihydrofolate reductase-thymidylate synthase0101
Solute carrier family 22 member 60001
Canalicular multispecific organic anion transporter 10102
Trifunctional purine biosynthetic protein adenosine-30101
Solute carrier family 22 member 200101
Dihydrofolate reductase 0101
Solute carrier family 22 member 80001
Solute carrier family 22 member 60101
Dihydrofolate reductase0101
ATP-binding cassette sub-family C member 110001
Proton-coupled folate transporter0101
Solute carrier family 22 member 110001
Protein-arginine deiminase type-40101
nuclear receptor subfamily 1, group I, member 21001
Indoleamine 2,3-dioxygenase 10101
nonstructural protein 11001
GTP-binding nuclear protein Ran isoform 11001
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA gyrase subunit A0101
DNA gyrase subunit B0101
Pyruvate kinase PKM0101
DNA gyrase subunit B0101
DNA gyrase subunit A0101
DNA topoisomerase 4 subunit A0101
DNA topoisomerase 4 subunit B0101
Chain A, AMINOPEPTIDASE0101
Chain A, AMINOPEPTIDASE0101
Voltage-dependent calcium channel subunit alpha-2/delta-10101
Plasma kallikrein0001
Alkaline phosphatase, tissue-nonspecific isozyme0101
Carbonic anhydrase 30001
Alkaline phosphatase, tissue-nonspecific isozyme 0101
Intestinal-type alkaline phosphatase0101
Intestinal-type alkaline phosphatase0101
5'-nucleotidase0101
Carbonic anhydrase 40001
Carbonic anhydrase 60001
Adenosine receptor A10001
Adenosine receptor A2a0001
Carbonic anhydrase 5A, mitochondrial0001
Glutamate receptor ionotropic, NMDA 1 0001
Carbonic anhydrase0001
Carbonic anhydrase 70001
Carbonic anhydrase0001
E3 ubiquitin-protein ligase XIAP0101
Glutamate receptor ionotropic, NMDA 2A 0001
Glutamate receptor ionotropic, NMDA 2B0001
Glutamate receptor ionotropic, NMDA 2C0001
SLC16A10 protein0001
Carbonic anhydrase 0001
Carbonic anhydrase-like protein, putative0001
Carbonic anhydrase0001
Carbonic anhydrase0001
Glutamate receptor ionotropic, NMDA 2D0001
Carbonic anhydrase 0001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3B0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Carbonic anhydrase 130001
Glutamate receptor ionotropic, NMDA 3A0001
Carbonic anhydrase 140001
Phospholipase A-2-activating protein0101
Carbonic anhydrase 5B, mitochondrial0001
Endolysin0011
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]