Page last updated: 2024-12-08

pinoxaden

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

pinoxaden: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

pinoxaden : A pyrazolooxadiazepine that is 7-oxo-1,2,4,5-tetrahydro-7H-pyrazolo[1,2-d][1,4,5]oxadiazepin which is substituted at positions 8 and 9 by 2,6-diethyl-4-methylphenyl and pivaloyloxy groups, respectively. A pro-herbicide (by hydrolysis of the pivalate ester to give the corresponding enol), it is used for control of grass weeds in cereal crops. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID210326
CHEMBL ID1866631
CHEBI ID83524
SCHEMBL ID64416
MeSH IDM0537917

Synonyms (35)

Synonym
243973-20-8
NCGC00163860-01
pinoxaden
[8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate
2,2-dimethylpropanoic acid [8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] ester
A845290
[8-(2,6-diethyl-4-methyl-phenyl)-7-oxidanylidene-1,2,4,5-tetrahydropyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl] 2,2-dimethylpropanoate
hsdb 7884
u55glf9lv9 ,
unii-u55glf9lv9
8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7h-pyrazolo(1,2-d)(1,4,5)oxadiazepin-9-yl 2,2-dimethylpropanoate
pinoxaden [iso]
propanoic acid, 2,2-dimethyl-, 8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7h-pyrazolo(1,2-d)(1,4,5)oxadiazepin-9-yl ester
SCHEMBL64416
CHEMBL1866631
chebi:83524 ,
pinoxaden [mi]
8-(2,6-diethyl-p-tolyl)-1,2,4,5-tetrahydro-7-oxo-7h-pyrazolo(1,2-d)(1,4,5)oxadiazepin-9-yl 2,2-dimethylpropionate
8-(2,6-diethyl-p-tolyl)-1,2,4,5-tetrahydro-7-oxo-7h-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl 2,2-dimethylpropionate
8-(2,6-diethyl-4-methylphenyl)-7-oxo-1,2,4,5-tetrahydro-7h-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl 2,2-dimethylpropanoate
dtxcid6014823
tox21_304033
dtxsid8034823 ,
NCGC00356993-01
cas-243973-20-8
propanoic acid, 2,2-dimethyl-, 8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7h-pyrazolo[1,2-d][1,4,5]oxadiazepin-9-yl ester
pinoxaden, pestanal(r), analytical standard
pinoxaden 100 microg/ml in acetonitrile
Q15632855
BCP30997
propanoic acid, 2,2-dimethyl-, 8-(2,6-diethyl-4-methylphenyl)-1,2,4,5-tetrahydro-7-oxo-7h-pyrazolo1,2-d1,4,5oxadiazepin-9-yl ester
FT-0778659
8-(2,6-diethyl-4-methylphenyl)-9-oxo-1h,2h,4h,5h,9h-pyrazolo[1,2-d][1,4,5]oxadiazepin-7-yl 2,2-dimethylpropanoate
EN300-1661086
Z2574926827

Research Excerpts

Overview

Pinoxaden is a new cereal herbicide that provides outstanding levels of post-emergence activity against a broad spectrum of grass weed species for worldwide selective use in both wheat and barley.

ExcerptReferenceRelevance
"Pinoxaden is a new cereal herbicide that provides outstanding levels of post-emergence activity against a broad spectrum of grass weed species for worldwide selective use in both wheat and barley."( Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
Cederbaum, F; Cornes, D; Friedmann, AA; Glock, J; Hall, G; Indolese, AF; Kloer, DP; Le Goupil, G; Maetzke, T; Meier, H; Muehlebach, M; Schneider, R; Stoller, A; Szczepanski, H; Wendeborn, S; Widmer, H, 2011
)
2.03

Dosage Studied

ExcerptRelevanceReference
" Dose-response experiment indicated that Lujiang population was highly resistant to fenoxaprop-p-ethyl (199."( Target-site mechanism of ACCase-inhibitors resistance in American sloughgrass (Beckmannia syzigachne Steud.) from China.
Du, L; Li, L; Liu, W; Wang, J; Yuan, G, 2014
)
0.4
" Dose-response experiments showed that the AHSX-1 population has evolved a very high level resistance to fenoxaprop-p-ethyl (RI = 275) and mesosulfuron-methyl (RI = 788)."( Multiple resistance to ACCase and AHAS-inhibiting herbicides in shortawn foxtail (Alopecurus aequalis Sobol.) from China.
Bi, Y; Du, L; Guo, W; Li, Q; Liu, W; Wang, J; Yuan, G; Zhang, C, 2015
)
0.42
" In this study, whole-plant dose-response assays were conducted to investigate the level of resistance in four resistant American sloughgrass populations (LY, JH, BYJ and BYP) to four ACCase-inhibiting herbicides belonging to aryloxyphenoxypropionates, cyclohexanediones, and phenylpyrazolines groups under greenhouse conditions."( Resistance of American sloughgrass (Bechmannia syzigachne) populations to ACCase-inhibiting herbicides involves three different target site mutations from China.
Chen, J; Tang, W; Zhang, Y; Zhou, F, 2015
)
0.42
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (5)

RoleDescription
xenobioticA xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
environmental contaminantAny minor or unwanted substance introduced into the environment that can have undesired effects.
agrochemicalAn agrochemical is a substance that is used in agriculture or horticulture.
EC 6.4.1.2 (acetyl-CoA carboxylase) inhibitorAn EC 6.4.1.* (C-C bond-forming ligase) inhibitor that interferes with the action of acetyl-CoA carboxylase (EC 6.4.1.2).
proherbicideA compound that, on administration, must undergo chemical conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the pharmacologically active herbicide for which it is a proherbicide.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
pivalate esterA carboxylic ester of pivalic acid.
pyrazolooxadiazepineAn organic heterobicyclic compound whose skeleton consists of a pyrazole ring ortho-fused to a diazepine ring.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (6)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AR proteinHomo sapiens (human)Potency0.00630.000221.22318,912.5098AID588515
retinoic acid nuclear receptor alpha variant 1Homo sapiens (human)Potency33.87820.003041.611522,387.1992AID1159552; AID1159555
estrogen-related nuclear receptor alphaHomo sapiens (human)Potency8.63490.001530.607315,848.9004AID1224841
pregnane X nuclear receptorHomo sapiens (human)Potency70.79460.005428.02631,258.9301AID720659
vitamin D (1,25- dihydroxyvitamin D3) receptorHomo sapiens (human)Potency0.00280.023723.228263.5986AID588543
v-jun sarcoma virus 17 oncogene homolog (avian)Homo sapiens (human)Potency35.81070.057821.109761.2679AID1159526; AID1159528
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (55)

Assay IDTitleYearJournalArticle
AID1111876Solubility in water at 25 degC2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103803Post-emergence herbicidal activity against Lolium rigidum at 30 g a.i./ha measured after 20 days2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111886Drug metabolism in Lolium perenne (perennial ryegrass) measured assessed as total inactive metabolites at 0.1 g/l after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111891Drug level in Lolium perenne (perennial ryegrass) measured at 0.1 g/l after 6 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111910Drug metabolism in Lolium perenne (perennial ryegrass) measured assessed as pinoxaden dione at 0.1 g/l after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111890Drug level in Lolium perenne (perennial ryegrass) measured at 0.1 g/l after 6 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111879Drug metabolism in Avena fatua assessed as total active parent at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111900Drug metabolism in winter Hordeum vulgare cv. Manitou (barley) assessed as pinoxaden dione at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111877Drug metabolism in Avena fatua assessed as total inactive metabolites at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111903Drug level in winter Hordeum vulgare cv. Manitou (barley) at 0.1 g/l measured after 6 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111911Drug metabolism in winter Triticum aestivum cv. Soisson (wheat) assessed as total active parent at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103813Post-emergence herbicidal activity against Alopecurus myosuroides at 30 g a.i./ha measured after 21 days in presence of 1% Merge adjuvant2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1103810Phytotoxicity against Hordeum vulgare cv. Fanfare (barley) at 60 g a.i./ha applied post-emergence measured after 12 days in presence of cloquintocet-mexyl2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111899Drug metabolism in winter Hordeum vulgare cv. Manitou (barley) assessed as total active parent at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103809Phytotoxicity against Triticum aestivum cv. Arina (wheat) at 60 g a.i./ha applied post-emergence measured after 12 days2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111878Drug metabolism in Avena fatua assessed as total inactive metabolites at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103842Half life of hydrolysis at pH 7 at 50 degC2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1103814Post-emergence herbicidal activity against Avena fatua at 30 g a.i./ha measured after 21 days in presence of 1% Merge adjuvant2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111895Drug metabolism in winter Triticum aestivum cv. Soisson (wheat) assessed as pinoxaden dione at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111887Drug metabolism in Lolium perenne (perennial ryegrass) measured assessed as total active parent at 0.1 g/l after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103807Phytotoxicity against Triticum aestivum cv. Remia (wheat) at 60 g a.i./ha applied post-emergence measured after 12 days2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111883Drug level in Avena fatua at 0.1 g/l measured after 6 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111894Drug metabolism in winter Triticum aestivum cv. Soisson (wheat) assessed as total active parent at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111889Drug metabolism in Lolium perenne (perennial ryegrass) measured assessed as pinoxaden dione at 0.1 g/l after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111914Drug level in winter Triticum aestivum cv. Soisson (wheat) measured after 6 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111892Drug metabolism in winter Triticum aestivum cv. Soisson (wheat) assessed as total inactive metabolites at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111901Drug metabolism in winter Hordeum vulgare cv. Manitou (barley) assessed as pinoxaden dione at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103811Phytotoxicity against Hordeum vulgare cv. Fanfare (barley) at 60 g a.i./ha applied post-emergence measured after 12 days2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111896Drug metabolism in winter Hordeum vulgare cv. Manitou (barley) assessed as total inactive metabolites at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111880Drug metabolism in Avena fatua assessed as total active parent at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111871Aqueous hydrolysis of the compound at pH 9 at 20 degC2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111872Aqueous hydrolysis of the compound at pH 4 at 20 degC2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111912Drug metabolism in winter Triticum aestivum cv. Soisson (wheat) assessed as pinoxaden dione at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103808Phytotoxicity against Triticum aestivum cv. Arina (wheat) at 60 g a.i./ha applied post-emergence measured after 12 days in presence of cloquintocet-mexyl2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1103812Post-emergence herbicidal activity against Lolium perenne (perennial ryegrass) at 30 g a.i./ha measured after 21 days in presence of 1% Merge adjuvant2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111888Drug metabolism in Lolium perenne (perennial ryegrass) measured assessed as total active parent at 0.1 g/l after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111897Drug metabolism in winter Hordeum vulgare cv. Manitou (barley) assessed as total inactive metabolites at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111885Drug metabolism in Lolium perenne (perennial ryegrass) measured assessed as total inactive metabolites at 0.1 g/l after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103799Post-emergence herbicidal activity against Setaria faberi (Giant Foxtail) at 30 g a.i./ha measured after 21 days in presence of 1% Merge adjuvant2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1103801Post-emergence herbicidal activity against Lolium rigidum at 30 g a.i./ha measured after 20 days in presence of cloquintocet-mexyl2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111893Drug metabolism in winter Triticum aestivum cv. Soisson (wheat) assessed as total inactive metabolites at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111882Drug metabolism in Avena fatua assessed as pinoxaden dione at 0.1 g/l measured after 16 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103805Post-emergence herbicidal activity against Avena fatua at 30 g a.i./ha measured after 20 days in presence of cloquintocet-mexyl2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111898Drug metabolism in winter Hordeum vulgare cv. Manitou (barley) assessed as total active parent at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103819Phytotoxicity against Hordeum vulgare (barley) at 30 g a.i./ha applied post-emergence measured after 21 days in presence of 1% Merge adjuvant2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1103804Post-emergence herbicidal activity against Avena fatua at 30 g a.i./ha measured after 20 days2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111884Drug level in Avena fatua at 0.1 g/l measured after 6 hr2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111874Aqueous hydrolysis of the compound at pH 7 at 20 degC2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111881Drug metabolism in Avena fatua assessed as pinoxaden dione at 0.1 g/l measured after 16 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111913Drug level in winter Triticum aestivum cv. Soisson (wheat) measured after 6 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1103818Phytotoxicity against Triticum aestivum (wheat) at 30 g a.i./ha applied post-emergence measured after 21 days in presence of 1% Merge adjuvant2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1103806Phytotoxicity against Triticum aestivum cv. Remia (wheat) at 60 g a.i./ha applied post-emergence measured after 12 days in presence of cloquintocet-mexyl2009Bioorganic & medicinal chemistry, Jun-15, Volume: 17, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part I: Discovery of the novel cereal herbicide pinoxaden.
AID1111902Drug level in winter Hordeum vulgare cv. Manitou (barley) at 0.1 g/l measured after 6 hr in presence of safener cloquintocet-mexyl2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111873Aqueous hydrolysis of the compound at pH 5 at 20 degC2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
AID1111875Lipophilicity, log P of the compound at 25 degC2011Pest management science, Dec, Volume: 67, Issue:12
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: chemistry and biology of the cereal herbicide pinoxaden.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (22)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (9.09)29.6817
2010's15 (68.18)24.3611
2020's5 (22.73)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 35.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index35.66 (24.57)
Research Supply Index3.14 (2.92)
Research Growth Index5.04 (4.65)
Search Engine Demand Index71.89 (26.88)
Search Engine Supply Index3.18 (0.95)

This Compound (35.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other22 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]