Page last updated: 2024-09-27

Transient Tachypnea of Newborn

Abnormal increase in RESPIRATORY RATE in the newborn. It is self-limiting and attributed to the delayed fetal lung fluid clearance often in CAESAREAN SECTION delivery.

Synonyms(2)

Synonym
Transient Tachypnea of Newborn
Transient Tachypnea of the Newborn

Research Excerpts

Overview

ExcerptReference
"Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress."( Bruschettini, M; Calevo, MG; Cohen, A; Gaiero, A; Moresco, L, 2016)
"Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress."( Baldi, F; Bruschettini, M; Calevo, MG; Cohen, A; Moresco, L, 2016)
"Transient tachypnea of newborn is associated with hypothyroxinemia in animals via decreased stimulation of beta-adrenergic receptors and Na-K-ATPase activity."( Almashanu, S; Makhoul, IR; Mashiach, T; Smolkin, T; Ulanovsky, I, 2016)
"Transient tachypnea of the newborn is characterized by tachypnea and signs of respiratory distress."( Bruschettini, M; Calevo, MG; Macchi, M; Moresco, L, 2021)

Research

Studies (46)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's34 (73.91)28.8240
2020's12 (26.09)9.53
DrugIndicatedRelationship StrengthStudiesTrials
n(g),n(g')-dimethyl-l-arginine0low10
lactic acid0low10
albuterol0medium52
furosemide0low20
gentamicin0low10
apnea0low20
procaterol0medium11
thyroxine0low20
penicillin g0low10
triiodothyronine0medium11
phenylephrine0low10
arginine0low10
bisphenol a0low10
nitrilotriacetic acid0low10
ephedrine0low10
betamethasone0low10
ferric nitrilotriacetate0low10
ursodeoxycholic acid0low10
amoxicillin0medium11
n,n-dimethylarginine0low10
arginine vasopressin0low10
pulmicort0medium32
phenylephrine hydrochloride0medium22
beta-escin0low10
natriuretic peptide, brain0medium51

Protein Targets (383)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
glp-1 receptor, partial6006
thioredoxin reductase7007
GLS protein4004
regulator of G-protein signaling 41001
estrogen-related nuclear receptor alpha9009
estrogen nuclear receptor alpha110011
NPYLR7B0011
arylsulfatase A3003
euchromatic histone-lysine N-methyltransferase 27007
thyroid stimulating hormone receptor4004
flap endonuclease 13003
peripheral myelin protein 224004
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Bile salt export pump0909
Beta-2 adrenergic receptor0347
Beta-1 adrenergic receptor0033
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Beta-3 adrenergic receptor0022
Delta-type opioid receptor0011
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
Beta-2 adrenergic receptor 0013
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Beta-2 adrenergic receptor0123
Canalicular multispecific organic anion transporter 10606
ATP-dependent phosphofructokinase3003
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Chain A, Beta-lactamase3003
Chain A, 2-oxoglutarate Oxygenase2002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
Beta-lactamase 0002
AR protein8008
apical membrane antigen 1, AMA14004
Beta-lactamase 0002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 12002
DNA polymerase eta isoform 12002
DNA polymerase iota isoform a (long)3003
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
DNA polymerase kappa isoform 12002
Bile salt export pump0202
Beta-lactamase SHV-10002
Beta-lactamase SHV-10002
Cytochrome P450 2C9 0202
Beta-lactamase0002
Kappa-type opioid receptor0002
Solute carrier family 15 member 10202
Solute carrier family 15 member 10101
Cytochrome P450 2J20202
B2 metallo-beta-lactamase 0002
Solute carrier family 15 member 20202
Beta-lactamase 0002
Beta-lactamase 0002
Solute carrier family 15 member 20202
Beta-lactamase 0002
Beta-lactamase 0002
ATAD5 protein, partial1001
TDP1 protein7007
Microtubule-associated protein tau1001
Bloom syndrome protein isoform 12002
D(1A) dopamine receptor2002
lamin isoform A-delta104004
neuropeptide S receptor isoform A2002
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase1001
NFKB1 protein, partial4004
thyroid stimulating hormone receptor5005
alpha-galactosidase1001
cytochrome P450 2C19 precursor2002
chromobox protein homolog 15005
muscarinic acetylcholine receptor M11001
lethal factor (plasmid)1001
Cytochrome P450 3A40001
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0102
Nitric oxide synthase, brain 0102
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
vitamin D3 receptor isoform VDRA1001
Translocator protein0011
Vasopressin V2 receptor0214
Oxytocin receptor0112
Vasopressin V1a receptor0022
Vasopressin V1a receptor0112
Vasopressin V1b receptor0112
Vasopressin V2 receptor0011
Vasopressin V1b receptor0113
Translocator protein0102
Oxytocin receptor0101
Vasopressin V2 receptor 0112
pregnane X receptor2002
GLI family zinc finger 34004
progesterone receptor4004
cytochrome P450 family 3 subfamily A polypeptide 47007
glucocorticoid receptor [Homo sapiens]6006
farnesoid X nuclear receptor4004
pregnane X nuclear receptor5005
vitamin D (1,25- dihydroxyvitamin D3) receptor2002
IDH12002
aryl hydrocarbon receptor6006
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a5005
nuclear receptor subfamily 1, group I, member 22002
thyroid hormone receptor beta isoform a5005
nuclear factor erythroid 2-related factor 2 isoform 21001
galanin receptor type 30101
nuclear factor erythroid 2-related factor 2 isoform 18008
Voltage-dependent calcium channel gamma-2 subunit3003
Glucocorticoid receptor0426
Glycine receptor subunit alpha-10404
Glutamate receptor 23003
Glycine receptor subunit beta0404
Glycine receptor subunit alpha-20404
Glycine receptor subunit alpha-30404
ORF730011
Chain A, Estrogen-related receptor gamma0011
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Luciferase1001
acetylcholinesterase2002
RAR-related orphan receptor gamma6006
GALC protein2002
caspase 7, apoptosis-related cysteine protease1001
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 32002
retinoic acid nuclear receptor alpha variant 15005
retinoid X nuclear receptor alpha2002
G3003
cytochrome P450 2D63003
peroxisome proliferator-activated receptor delta3003
peroxisome proliferator activated receptor gamma6006
caspase-31001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
Histone H2A.x1001
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 11001
potassium voltage-gated channel subfamily H member 2 isoform d1001
thyroid hormone receptor beta isoform 25005
importin subunit beta-1 isoform 11001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
cytochrome P450 3A4 isoform 12002
Gamma-aminobutyric acid receptor subunit pi2013
GTPase KRas0011
Interferon beta3003
HLA class I histocompatibility antigen, B alpha chain 3003
Estrogen receptor0314
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10101
Cellular tumor antigen p535005
Aldo-keto reductase family 1 member B10202
Androgen receptor0202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Androgen receptor0404
Gamma-aminobutyric acid receptor subunit beta-12013
Gamma-aminobutyric acid receptor subunit delta2013
Gamma-aminobutyric acid receptor subunit gamma-22013
Gamma-aminobutyric acid receptor subunit alpha-52013
Gamma-aminobutyric acid receptor subunit alpha-32013
Gamma-aminobutyric acid receptor subunit gamma-12013
Gamma-aminobutyric acid receptor subunit alpha-22013
Sodium-dependent noradrenaline transporter 0202
Gamma-aminobutyric acid receptor subunit alpha-42013
Gamma-aminobutyric acid receptor subunit gamma-32013
Gamma-aminobutyric acid receptor subunit alpha-62013
Sodium-dependent serotonin transporter0202
5-hydroxytryptamine receptor 60202
Nuclear receptor ROR-gamma1001
Estrogen-related receptor gamma0101
Gamma-aminobutyric acid receptor subunit alpha-12013
Gamma-aminobutyric acid receptor subunit beta-32013
Gamma-aminobutyric acid receptor subunit beta-22013
Sodium-dependent dopamine transporter 0202
GTP-binding protein Rheb0011
GABA theta subunit2013
Inositol hexakisphosphate kinase 13003
Estrogen receptor beta0213
Gamma-aminobutyric acid receptor subunit epsilon2013
cytochrome P450 2C9, partial3003
67.9K protein1001
aldehyde dehydrogenase 1 family, member A11001
EWS/FLI fusion protein3003
thyrotropin-releasing hormone receptor1001
geminin6006
Solute carrier family 22 member 60202
Carbonic anhydrase 120102
Carbonic anhydrase 10102
Carbonic anhydrase 20102
Albumin0101
Carbonic anhydrase 30101
Glucose-6-phosphate 1-dehydrogenase0101
Carbonic anhydrase 40102
Carbonic anhydrase 60102
Serum paraoxonase/arylesterase 10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
Carbonic anhydrase 5A, mitochondrial0102
Carbonic anhydrase 70102
Adenosine receptor A10101
Corticosteroid 11-beta-dehydrogenase isozyme 10101
6-phosphogluconate dehydrogenase, decarboxylating0101
Spike glycoprotein2002
Holo-[acyl-carrier-protein] synthase0101
Solute carrier organic anion transporter family member 2A10101
Sodium/bile acid cotransporter0202
Carbonic anhydrase 90102
Multidrug and toxin extrusion protein 10101
Carbonic anhydrase 130102
G-protein coupled receptor 350112
CDGSH iron-sulfur domain-containing protein 10404
Carbonic anhydrase 140102
Broad substrate specificity ATP-binding cassette transporter ABCG20101
Carbonic anhydrase 5B, mitochondrial0102
v-jun sarcoma virus 17 oncogene homolog (avian)3003
cellular tumor antigen p53 isoform a1001
Integrin beta-31001
Integrin alpha-IIb1001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10102
N(G),N(G)-dimethylarginine dimethylaminohydrolase 10001
Atrial natriuretic peptide receptor 10101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, JmjC domain-containing histone demethylation protein 3A1001
nonstructural protein 10101
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
serine/threonine-protein kinase PLK12002
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase type 20001
Metallo-beta-lactamase VIM-11 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-19 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-beta-lactamase0001
Beta-lactamase 0001
streptokinase A precursor0011
Beta-lactamase0001
Solute carrier family 22 member 80102
Beta-lactamase0001
Beta-lactamase 10001
Beta-lactamase0001
Beta-lactamase OXA-100001
Beta-lactamase0001
Beta-lactamase TEM0102
Guanine nucleotide-binding protein G2002
Beta-lactamase0001
Metallo-beta-lactamase VIM-130001
Beta-lactamase 0001
Efflux transporter 0001
Beta-lactamase 0001
Metallo-beta-lactamase VIM-20001
Beta-lactamase Toho-10001
Beta-lactamase 0001
Class D beta-lactamase0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Beta-lactamase 0001
Metallo-b-lactamase 0001
Beta-lactamase IMP-1 0001
BlaVIM-1 0001
Beta-lactamase 0001
Solute carrier family 22 member 80101
Beta-lactamase 0001
Carbapenem-hydrolyzing beta-lactamase KPC0001
Beta-lactamase class B VIM-2 0001
Beta-lactamase 0001
Solute carrier family 22 member 80102
Beta-lactamase VIM-1 0001
dopamine D1 receptor1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
Alpha-1B adrenergic receptor 0011
ras-related protein Rab-9A1001
Alpha-2A adrenergic receptor0112
POU domain, class 2, transcription factor 10001
Alpha-1B adrenergic receptor0101
Alpha-2B adrenergic receptor0101
Beta-1 adrenergic receptor0101
Alpha-1A adrenergic receptor0112
Alpha-2C adrenergic receptor0112
Alpha-1B adrenergic receptor0101
Alpha-2B adrenergic receptor0101
Alpha-2C adrenergic receptor0101
Alpha-2A adrenergic receptor0101
Alpha-1D adrenergic receptor0101
Alpha-2B adrenergic receptor0001
Alpha-1A adrenergic receptor0112
Alpha-1B adrenergic receptor0112
Alpha-1A adrenergic receptor0101
Alpha-2C adrenergic receptor0001
Alpha-2A adrenergic receptor0001
beta-2 adrenergic receptor1001
lysosomal alpha-glucosidase preproprotein1001
mu-type opioid receptor isoform MOR-10011
Vpr1001
5-hydroxytryptamine receptor 2A0011
Neuronal acetylcholine receptor subunit alpha-41001
Neuronal acetylcholine receptor subunit beta-21001
D(2) dopamine receptor0101
SMAD family member 21001
SMAD family member 31001
Thrombopoietin1001
glucocerebrosidase2002
activating transcription factor 61001
nuclear receptor ROR-gamma isoform 11001
survival motor neuron protein isoform d1001
Interleukin-50101
Interleukin-50101
Progesterone receptor0101
Glucocorticoid receptor0101
Mineralocorticoid receptor 0112
Matrix metalloproteinase-90101
Interleukin-5 receptor subunit alpha0101
Sodium-dependent serotonin transporter0101
ATPase family AAA domain-containing protein 51001
Ataxin-21001
Chain X, Thyroid hormone receptor beta-10022
Chain X, Thyroid hormone receptor beta-10022
USP1 protein, partial2002
Solute carrier organic anion transporter family member 1A40103
Nuclear receptor subfamily 1 group I member 20011
Solute carrier organic anion transporter family member 1A50002
Rap guanine nucleotide exchange factor 31001
Transthyretin0103
Thyroid hormone receptor alpha0235
Thyroid hormone receptor beta0235
Proliferating cell nuclear antigen0202
Retinoic acid receptor RXR-alpha0022
UDP-glucuronosyltransferase 1A1 0101
Peroxisome proliferator-activated receptor gamma0044
Malate dehydrogenase, mitochondrial0101
Solute carrier organic anion transporter family member 1A20002
Solute carrier organic anion transporter family member 1A30002
Solute carrier organic anion transporter family member 4C10102
Monocarboxylate transporter 80001
Bile acid receptor0112
Solute carrier organic anion transporter family member 1C10001
Solute carrier organic anion transporter family member 1B10002
muscleblind-like protein 1 isoform 11001
Gamma-aminobutyric acid receptor subunit pi0101
Gamma-aminobutyric acid receptor subunit delta0101
Prothrombin0011
Gamma-aminobutyric acid receptor subunit alpha-10101
Thyroid hormone receptor beta0101
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit beta-30101
Adenosine receptor A10202
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit beta-20101
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit epsilon0101
Gamma-aminobutyric acid receptor subunit alpha-60101
Sigma non-opioid intracellular receptor 10011
Solute carrier organic anion transporter family member 4C10001
Gamma-aminobutyric acid receptor subunit gamma-10101
Solute carrier organic anion transporter family member 4A10001
Gamma-aminobutyric acid receptor subunit gamma-30101
Solute carrier organic anion transporter family member 1C10101
Solute carrier organic anion transporter family member 1B30001
Gamma-aminobutyric acid receptor subunit theta0101
Ubiquitin carboxyl-terminal hydrolase 20101
Vitamin D3 receptor0112
Alpha-synuclein1001
Ileal sodium/bile acid cotransporter0101
TAR DNA-binding protein 431001
G-protein coupled bile acid receptor 10011
M1-family alanyl aminopeptidase0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]