Post Exercise Hypotension

Transient reduction in blood pressure levels immediately after exercises that lasts 2-12 hours. The reduction varies but is typically 5-20 mm Hg when compared to pre-exercise levels. It exists both in normotensive and hypertensive individuals and may play a role in excercise related PHYSIOLOGIC ADAPTATION.

Synonym
Post Exercise Hypotension
Post-Exercise Hypotension
Postexercise Hypotension

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	17 (73.91)	28.8240
2020's	6 (26.09)	9.53

Drug	Relationship Strength	Studies	Trials
histamine	low	1	0
nitrates	medium	2	2
nitrites	medium	2	1
phenylephrine	low	1	0
arginine	medium	2	2
citrulline	medium	2	1
diltiazem	low	1	0
captopril	medium	1	1
thromboxanes	low	1	0
citrulline malate	medium	2	1
bradykinin	low	1	0
arachidonic acid	low	1	0
dinoprostone	low	1	0
5-hydroxy-6,8,11,14-eicosatetraenoic acid	low	1	0
20-hydroxy-5,8,11,14-eicosatetraenoic acid	low	1	0
12-hydroxy-5,8,10,14-eicosatetraenoic acid	low	1	0
15-hydroxy-5,8,11,13-eicosatetraenoic acid	low	1	0
atrial natriuretic factor	medium	1	1
cardiovascular agents	low	1	0
ecallantide	low	1	0

Protein Targets (310)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Microtubule-associated protein tau	3	0	0	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Inositol monophosphatase 1	1	0	0	1
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	5	0	0	5
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	1	1
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	1	0	0	1
Chain A, Beta-lactamase	2	0	0	2
Chain A, HADH2 protein	2	0	0	2
Chain B, HADH2 protein	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	2	0	0	2
Chain A, ATP-DEPENDENT DNA HELICASE Q1	1	0	0	1
Chain A, Cruzipain	2	0	0	2
15-lipoxygenase, partial	2	0	0	2
phosphopantetheinyl transferase	4	0	0	4
USP1 protein, partial	2	0	0	2
TDP1 protein	3	0	0	3
thioredoxin glutathione reductase	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	1	0	0	1
euchromatic histone-lysine N-methyltransferase 2	5	0	0	5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	1	0	0	1
Bloom syndrome protein isoform 1	1	0	0	1
cellular tumor antigen p53 isoform a	1	0	0	1
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	2	0	0	2
vitamin D3 receptor isoform VDRA	2	0	0	2
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
nuclear receptor ROR-gamma isoform 1	1	0	0	1
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
DNA polymerase kappa isoform 1	1	0	0	1
cytochrome P450 3A4 isoform 1	2	0	0	2
histone acetyltransferase KAT2A isoform 1	3	0	0	3
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	0	0	1
caspase-1 isoform alpha precursor	1	0	0	1
lamin isoform A-delta10	4	0	0	4
Fatty-acid amide hydrolase 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Prostaglandin G/H synthase 1	0	0	0	1
Trypsin	0	1	0	1
Coagulation factor VII	0	1	0	1
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Aromatase	0	1	0	1
Tissue factor	0	1	0	1
Fatty acid-binding protein, adipocyte	0	1	1	2
Gamma-aminobutyric acid receptor subunit beta-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit delta	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-2	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-5	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-4	2	0	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit alpha-6	2	0	0	2
Prostaglandin G/H synthase 2	0	1	1	3
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Histamine H2 receptor	2	0	1	3
10 kDa heat shock protein, mitochondrial	0	1	0	1
Calmodulin	0	0	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-3	2	0	0	2
Gamma-aminobutyric acid receptor subunit beta-2	2	0	0	2
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Prostaglandin G/H synthase 2	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	2
Fatty acid-binding protein 5	0	1	0	1
Fatty acid-binding protein 5	0	0	1	1
Thiosulfate sulfurtransferase	0	1	0	1
Lanosterol 14-alpha demethylase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
GABA theta subunit	2	0	0	2
Gamma-aminobutyric acid receptor subunit epsilon	2	0	0	2
Solute carrier organic anion transporter family member 1B3	0	2	0	2
Cytosolic phospholipase A2 gamma	0	1	0	1
Transient receptor potential cation channel subfamily V member 2	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	2	0	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
thioredoxin reductase	4	0	0	4
NFKB1 protein, partial	2	0	0	2
GLS protein	3	0	0	3
thyroid stimulating hormone receptor	5	0	0	5
alpha-galactosidase	1	0	0	1
cytochrome P450 2C19 precursor	1	0	0	1
chromobox protein homolog 1	2	0	0	2
flap endonuclease 1	1	0	0	1
DNA polymerase iota isoform a (long)	2	0	0	2
muscarinic acetylcholine receptor M1	1	0	0	1
lethal factor (plasmid)	1	0	0	1
Cytochrome P450 3A4	0	2	1	5
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, brain	0	1	0	2
Nitric oxide synthase, inducible	0	0	0	1
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	2	0	0	2
Atrial natriuretic peptide receptor 1	0	0	1	1
Atrial natriuretic peptide receptor 1	0	0	1	1
Angiotensin-converting enzyme	0	2	1	4
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
Chain A, angiotensin converting enzyme	0	1	0	1
Chain A, angiotensin converting enzyme	0	1	0	1
Thrombopoietin	1	0	0	1
AR protein	3	0	0	3
cytochrome P450 family 3 subfamily A polypeptide 4	2	0	0	2
Metallo-beta-lactamase type 2	0	1	1	2
peripheral myelin protein 22 isoform 1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
transient receptor potential cation channel subfamily V member 1	1	0	0	1
ATP-binding cassette sub-family C member 3	0	2	0	2
Multidrug resistance-associated protein 4	0	2	0	3
Bile salt export pump	0	4	0	4
Prothrombin	0	1	0	1
Renin	0	1	0	1
Neprilysin	0	1	0	1
Neprilysin	0	1	0	1
Leukotriene A-4 hydrolase	0	2	1	3
EEF1AKMT4-ECE2 readthrough transcript protein	0	1	0	1
Angiotensin-converting enzyme	0	2	0	3
Leukotriene A-4 hydrolase	0	1	0	1
Thymidine phosphorylase	0	0	1	1
Prostaglandin G/H synthase 1	0	1	0	1
Endothelin-converting enzyme 1	0	1	0	1
Succinyl-diaminopimelate desuccinylase	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Solute carrier family 15 member 1	0	1	0	1
Beta-lactamase TEM	0	1	0	1
Mu-type opioid receptor	0	0	1	1
TAR DNA-binding protein 43	1	0	0	1
Beta-lactamase	0	2	0	3
Canalicular multispecific organic anion transporter 1	0	2	0	2
Beta-lactamase	0	2	0	2
Angiotensin-converting enzyme 2	0	1	0	1
Beta-lactamase class B VIM-2	0	1	1	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
General amino-acid permease GAP1	0	0	0	1
RAR-related orphan receptor gamma	1	0	0	1
estrogen receptor 2 (ER beta)	1	0	0	1
regulator of G-protein signaling 4	3	0	0	3
glucocorticoid receptor [Homo sapiens]	2	0	0	2
retinoid X nuclear receptor alpha	2	0	0	2
estrogen-related nuclear receptor alpha	2	0	0	2
pregnane X nuclear receptor	1	0	0	1
estrogen nuclear receptor alpha	2	0	0	2
cytochrome P450 2D6	1	0	0	1
glucocerebrosidase	1	0	0	1
D(1A) dopamine receptor	2	0	0	2
thyroid hormone receptor beta isoform 2	3	0	0	3
huntingtin isoform 2	1	0	0	1
Solute carrier family 22 member 1	0	1	0	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1F	0	1	0	1
Cellular tumor antigen p53	2	0	0	2
ATP-dependent translocase ABCB1	0	1	0	1
Cytochrome P450 2C9	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
Sodium channel protein type 1 subunit alpha	0	1	0	1
Sodium channel protein type 4 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Cytochrome P450 2J2	0	1	0	1
Spike glycoprotein	1	0	0	1
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Potassium voltage-gated channel subfamily H member 2	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1S	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Sodium channel protein type 5 subunit alpha	0	1	0	1
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Sodium channel protein type 3 subunit alpha	0	1	0	1
Sodium channel protein type 11 subunit alpha	0	1	0	1
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
SMAD family member 2	1	0	0	1
SMAD family member 3	1	0	0	1
GLI family zinc finger 3	1	0	0	1
retinoic acid nuclear receptor alpha variant 1	1	0	0	1
farnesoid X nuclear receptor	1	0	0	1
thyroid stimulating hormone receptor	1	0	0	1
activating transcription factor 6	1	0	0	1
prostaglandin E2 receptor EP2 subtype	1	0	0	1
mitogen-activated protein kinase 1	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	1	0	0	1
geminin	1	0	0	1
peripheral myelin protein 22	1	0	0	1
Solute carrier family 22 member 2	0	0	0	2
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier family 22 member 6	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 20	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Solute carrier family 22 member 6	0	1	0	1
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
GALC protein	1	0	0	1
apical membrane antigen 1, AMA1	1	0	0	1
EWS/FLI fusion protein	2	0	0	2
bromodomain adjacent to zinc finger domain 2B	1	0	0	1
potassium voltage-gated channel subfamily H member 2 isoform d	1	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 12	0	0	0	1
Solute carrier family 22 member 3	0	1	0	2
Carbonic anhydrase 1	0	2	0	3
Carbonic anhydrase 2	0	2	0	4
Plasma kallikrein	0	0	0	1
Carbonic anhydrase 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Carbonic anhydrase 4	0	2	0	3
Carbonic anhydrase 6	0	0	0	1
Histamine H2 receptor	0	1	2	3
Adenosine receptor A1	0	0	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Adenosine receptor A2a	0	0	0	1
Histamine H1 receptor	0	1	2	3
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Carbonic anhydrase 5A, mitochondrial	0	0	0	1
Histamine H1 receptor	0	2	2	4
Glutamate receptor ionotropic, NMDA 1	0	0	0	1
Carbonic anhydrase	0	2	0	3
Carbonic anhydrase 7	0	0	0	1
Carbonic anhydrase	0	0	0	2
Histamine H3 receptor	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	0	0	1
Glutamate receptor ionotropic, NMDA 2B	0	0	0	1
Glutamate receptor ionotropic, NMDA 2C	0	0	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase 9	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase-like protein, putative	0	0	0	1
Carbonic anhydrase	0	0	0	2
Carbonic anhydrase	0	0	0	2
Glutamate receptor ionotropic, NMDA 2D	0	0	0	1
Solute carrier family 22 member 1	0	1	0	2
Carbonic anhydrase	0	0	0	2
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	1
Glutamate receptor ionotropic, NMDA 3B	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 15	0	2	0	3
Carbonic anhydrase 13	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H3 receptor	0	1	0	1
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Glutamate receptor ionotropic, NMDA 3A	0	0	0	1
Carbonic anhydrase 14	0	0	0	1
Carbonic anhydrase 5B, mitochondrial	0	0	0	1
Histamine H3 receptor	0	1	2	3
Sodium/iodide cotransporter	0	1	0	1
dopamine D1 receptor	1	0	0	1
glp-1 receptor, partial	1	0	0	1
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	1	0	0	1
Alpha-1B adrenergic receptor	0	0	1	1
ras-related protein Rab-9A	1	0	0	1
Beta-2 adrenergic receptor	0	0	1	1
Beta-1 adrenergic receptor	0	0	1	1
Alpha-2A adrenergic receptor	0	1	1	2
Beta-3 adrenergic receptor	0	0	1	1
POU domain, class 2, transcription factor 1	0	0	0	1
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-2C adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Alpha-1D adrenergic receptor	0	1	0	1
Alpha-2B adrenergic receptor	0	0	0	1
Alpha-1A adrenergic receptor	0	1	1	2
Alpha-1B adrenergic receptor	0	1	1	2
Alpha-1A adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	0	0	1
Alpha-2A adrenergic receptor	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Research

Studies (23)

Protein Targets (310)

Post Exercise Hypotension

Synonyms(3)

Research Excerpts

Research

Studies (23)

Drugs Studied (27)

Protein Targets (310)