Page last updated: 2024-11-12
melanotan-1
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 16197727 |
| MeSH ID | M0089943 |
Synonyms (15)
| Synonym |
|---|
| alpha-ndp-msh |
| [nle4,dphe7]alpha-msh |
| gtpl1324 |
| NCGC00167334-01 |
| afamelanotide (usan/inn) |
| D10511 |
| melanotan 1 |
| DB04931 |
| bdbm50017181 |
| Q410794 |
| DTXSID40226843 , |
| (nle4,dphe7)alpha-msh |
| d02bb02 |
| dtxcid70149334 |
| AKOS040763896 |
Roles (1)
| Role | Description |
|---|
| dermatologic drug | A drug used to treat or prevent skin disorders or for the routine care of skin. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (1)
| Class | Description |
|---|
| polypeptide | A peptide containing ten or more amino acid residues. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346180 | Human MC5 receptor (Melanocortin receptors) | 2002 | European journal of pharmacology, Apr-12, Volume: 440, Issue:2-3
| The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. |
| AID1346171 | Human MC4 receptor (Melanocortin receptors) | 1999 | European journal of pharmacology, Aug-13, Volume: 378, Issue:3
| Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat. |
| AID1346178 | Human MC3 receptor (Melanocortin receptors) | 1999 | European journal of pharmacology, Aug-13, Volume: 378, Issue:3
| Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat. |
| AID1346231 | Human MC1 receptor (Melanocortin receptors) | 1988 | Endocrine reviews, Feb, Volume: 9, Issue:1
| Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues. |
| AID1346171 | Human MC4 receptor (Melanocortin receptors) | 1980 | Proceedings of the National Academy of Sciences of the United States of America, Oct, Volume: 77, Issue:10
| 4-Norleucine, 7-D-phenylalanine-alpha-melanocyte-stimulating hormone: a highly potent alpha-melanotropin with ultralong biological activity. |
| AID1346231 | Human MC1 receptor (Melanocortin receptors) | 2002 | European journal of pharmacology, Apr-12, Volume: 440, Issue:2-3
| The role of melanocortins in body weight regulation: opportunities for the treatment of obesity. |
| AID1346171 | Human MC4 receptor (Melanocortin receptors) | 2000 | Biochemistry, Dec-05, Volume: 39, Issue:48
| Molecular determinants of ligand binding to the human melanocortin-4 receptor. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (40.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 3 (60.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |