L-leucine transport

Definition

Target type: biologicalprocess

The directed movement of L-leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. [GOC:ai]

L-leucine transport is a crucial process in cellular metabolism, enabling cells to acquire this essential amino acid from their surroundings. L-leucine, a branched-chain amino acid, plays vital roles in protein synthesis, energy production, and various metabolic pathways. The transport of L-leucine across the cell membrane is facilitated by specific membrane-bound proteins called amino acid transporters. These transporters are highly selective, recognizing L-leucine and other branched-chain amino acids with high affinity. The mechanism of L-leucine transport can be categorized into two main types: active transport and passive transport. Active transport involves the use of energy to move L-leucine against its concentration gradient, from a region of low concentration to a region of high concentration. This energy is typically provided by ATP hydrolysis, which drives the movement of L-leucine into the cell. One example of an active transporter involved in L-leucine uptake is the sodium-dependent L-type amino acid transporter 1 (LAT1), which couples the inward movement of L-leucine with the inward movement of sodium ions. Passive transport, on the other hand, does not require energy and relies on the concentration gradient of L-leucine. In this case, L-leucine moves from a region of high concentration to a region of low concentration, following the direction of the gradient. The transport process is further influenced by factors such as the presence of other amino acids, the pH of the environment, and the availability of energy. Overall, L-leucine transport is a complex and tightly regulated process that plays a critical role in maintaining cellular homeostasis and supporting essential biological functions.'
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Proteins (2)

Compounds (23)