methacetin has been researched along with Hepatitis, Chronic in 3 studies
methacetin: RN given refers to parent cpd
methacetin : A member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group.
Hepatitis, Chronic: INFLAMMATION of the LIVER with ongoing hepatocellular injury for 6 months or more, characterized by NECROSIS of HEPATOCYTES and inflammatory cell (LEUKOCYTES) infiltration. Chronic hepatitis can be caused by viruses, medications, autoimmune diseases, and other unknown factors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methacetin breath test was correlated with liver function tests and serum bile acids." | 2.71 | Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels. ( Capodicasa, S; Colaiocco-Ferrante, L; Colecchia, A; Festi, D; Mazzella, G; Portincasa, P; Roda, E; Sandri, L; Simoni, P; Staniscia, T; Vestito, A; Vitacolonna, E, 2005) |
| "For the diagnosis of liver cirrhosis and correlations with liver fibrosis, the accuracy of the PBT at 30 min (PBT30) was similar to that of the MethaBT at 15 min (Metha15)." | 1.38 | Liver function assessment with three (13)C breath tests by two-point measurements. ( Asai, S; Ishii, Y; Murai, I; Suzuki, S, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishii, Y | 1 |
| Suzuki, S | 1 |
| Asai, S | 1 |
| Murai, I | 1 |
| Festi, D | 1 |
| Capodicasa, S | 1 |
| Sandri, L | 1 |
| Colaiocco-Ferrante, L | 1 |
| Staniscia, T | 1 |
| Vitacolonna, E | 1 |
| Vestito, A | 1 |
| Simoni, P | 1 |
| Mazzella, G | 1 |
| Portincasa, P | 1 |
| Roda, E | 1 |
| Colecchia, A | 1 |
| Tang, ZD | 1 |
| Qiu, YQ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252] | Phase 1 | 19 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| Development of a Breath Test for Monitoring Liver Metabolic Function in Patients With Chronic Liver Disease and Cirrhosis[NCT00244569] | Phase 3 | 120 participants (Anticipated) | Interventional | 2005-09-30 | Completed | ||
| Use of the BreathID to Assess Hepatic Metabolic Reserve and to Predict Hepatic Decompensation in Patients With Cirrhosis in Need of Liver Transplantation[NCT00375011] | 200 participants (Anticipated) | Observational | 2008-09-30 | Terminated (stopped due to Company restructured and protocol restructured. Resubmitted with IDE approval under new company name-Exalenz) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for methacetin and Hepatitis, Chronic
2 other studies available for methacetin and Hepatitis, Chronic
| Article | Year |
|---|---|
Liver function assessment with three (13)C breath tests by two-point measurements.
Topics: Acetamides; Aged; Breath Tests; Carbon Dioxide; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; | 2012 |
[Assessment of liver function with the 13C methacetin breath test].
Topics: Acetamides; Adolescent; Adult; Breath Tests; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; Li | 1986 |