methacetin has been researched along with Obesity in 5 studies
methacetin: RN given refers to parent cpd
methacetin : A member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of investigations had showed the high efficiency of the combination of atorvastatin with telmisartan in patients with arterial hypertension combined with obesity and NAFLD." | 9.19 | Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis. ( Bochar, OM, 2014) |
| "The results of investigations had showed the high efficiency of the combination of atorvastatin with telmisartan in patients with arterial hypertension combined with obesity and NAFLD." | 5.19 | Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis. ( Bochar, OM, 2014) |
| "Overweight, obesity and liver fat accumulation manifest with deranged portal extraction efficiency of methacetin into the steatotic hepatocyte." | 4.31 | Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease. ( Andrade, R; Bonfrate, L; Di Ciaula, A; Macedo, MP; Pina, A; Portincasa, P; Raposo, JF; Ribeiro, R; Shanmugam, H, 2023) |
| " The present study was conducted on 39 (20 lean and 19 obese) hypertransaminasemic patients with histologically proven NAFLD {ranging from simple steatosis to severe steatohepatitis [NASH (non-alcoholic steatohepatitis)] and fibrosis} and 28 (20 lean and eight overweight) healthy controls, who underwent stable isotope breath testing ([(13)C]methacetin and [(13)C]ketoisocaproate) for microsomal and mitochondrial liver function in relation to histology, serum hyaluronate, as a marker of liver fibrosis, and body size." | 3.73 | Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis. ( Grattagliano, I; Lauterburg, BH; Palasciano, G; Palmieri, VO; Portincasa, P; Stellaard, F, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Ciaula, A | 2 |
| Shanmugam, H | 1 |
| Ribeiro, R | 1 |
| Pina, A | 1 |
| Andrade, R | 1 |
| Bonfrate, L | 2 |
| Raposo, JF | 1 |
| Macedo, MP | 1 |
| Portincasa, P | 3 |
| Carbone, F | 1 |
| Shanmugham, H | 1 |
| Molina-Molina, E | 1 |
| Ministrini, S | 1 |
| Montecucco, F | 1 |
| Lock, JF | 1 |
| Westphal, T | 1 |
| Rubin, T | 1 |
| Malinowski, M | 1 |
| Schulz, A | 1 |
| Jara, M | 1 |
| Bednarsch, J | 1 |
| Stockmann, M | 1 |
| Bochar, OM | 1 |
| Grattagliano, I | 1 |
| Lauterburg, BH | 1 |
| Palmieri, VO | 1 |
| Palasciano, G | 1 |
| Stellaard, F | 1 |
1 trial available for methacetin and Obesity
| Article | Year |
|---|---|
Combined effect of appointment telmisartan and atorvastatin on hemodynamic indicators and the indicators of lipid profile in patients with arterial hypertension combined with obesity and steatohepatitis.
Topics: Acetamides; Adipokines; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Benzimidazo | 2014 |
4 other studies available for methacetin and Obesity
| Article | Year |
|---|---|
Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Dis | 2023 |
Adiponectin involved in portal flow hepatic extraction of 13C-methacetin in obesity and non-alcoholic fatty liver.
Topics: Acetamides; Adiponectin; Adult; Carbon Isotopes; Humans; Liver; Non-alcoholic Fatty Liver Disease; O | 2021 |
LiMAx Test Improves Diagnosis of Chemotherapy-Associated Liver Injury Before Resection of Colorectal Liver Metastases.
Topics: Acetamides; Aged; Algorithms; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chemoth | 2017 |
Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis.
Topics: Acetamides; Adult; Age Distribution; Biomarkers; Body Mass Index; Body Weight; Breath Tests; Caproat | 2006 |