methacetin has been researched along with Overweight in 2 studies
methacetin: RN given refers to parent cpd
methacetin : A member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group.
Overweight: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal over fat.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Overweight, obesity and liver fat accumulation manifest with deranged portal extraction efficiency of methacetin into the steatotic hepatocyte." | 4.31 | Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease. ( Andrade, R; Bonfrate, L; Di Ciaula, A; Macedo, MP; Pina, A; Portincasa, P; Raposo, JF; Ribeiro, R; Shanmugam, H, 2023) |
| " The present study was conducted on 39 (20 lean and 19 obese) hypertransaminasemic patients with histologically proven NAFLD {ranging from simple steatosis to severe steatohepatitis [NASH (non-alcoholic steatohepatitis)] and fibrosis} and 28 (20 lean and eight overweight) healthy controls, who underwent stable isotope breath testing ([(13)C]methacetin and [(13)C]ketoisocaproate) for microsomal and mitochondrial liver function in relation to histology, serum hyaluronate, as a marker of liver fibrosis, and body size." | 3.73 | Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis. ( Grattagliano, I; Lauterburg, BH; Palasciano, G; Palmieri, VO; Portincasa, P; Stellaard, F, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Ciaula, A | 1 |
| Shanmugam, H | 1 |
| Ribeiro, R | 1 |
| Pina, A | 1 |
| Andrade, R | 1 |
| Bonfrate, L | 1 |
| Raposo, JF | 1 |
| Macedo, MP | 1 |
| Portincasa, P | 2 |
| Grattagliano, I | 1 |
| Lauterburg, BH | 1 |
| Palmieri, VO | 1 |
| Palasciano, G | 1 |
| Stellaard, F | 1 |
2 other studies available for methacetin and Overweight
| Article | Year |
|---|---|
Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Dis | 2023 |
Liver breath tests non-invasively predict higher stages of non-alcoholic steatohepatitis.
Topics: Acetamides; Adult; Age Distribution; Biomarkers; Body Mass Index; Body Weight; Breath Tests; Caproat | 2006 |