methacetin has been researched along with Liver Cirrhosis in 36 studies
methacetin: RN given refers to parent cpd
methacetin : A member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group.
Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study was carried out to evaluate the role of 13C-methacetin breath test 13C-MBT) as a non invasive tool for liver fibrosis staging in patients with chronic hepatitis C (CHC)." | 9.19 | Role of 13C methacetin breath test for non invasive staging of liver fibrosis in patients with chronic hepatitis C. ( Cristian, B; Fierbinteanu-Braticevici, C; Papacocea, R; Tribus, L, 2014) |
| "The non-invasive (13)C-methacetin ((13)C-MBT) breath test has been proposed as a measure of metabolic liver function that improves the diagnostic efficacy of serologic and biochemical tests in assessing hepatic functional capacity and liver disease severity, The goal of this study was to establish the clinical utility of this test in quantifying hepatic metabolic function in patients with liver cirrhosis of varying severity and to compare (13)C-MBT measurements with the AST/ALT ratio, APRI score, and other routine liver tests." | 7.79 | ¹³C-methacetin breath test in the evaluation of disease severity in patients with liver cirrhosis. ( Hendrichova, M; Horak, J; Kolarova, H; Kratka, K; Rosina, J; Vranova, J, 2013) |
| "The (13)C-methacetin-breath test and also several noninvasive blood tests comprising routine laboratory parameters have been proposed to predict fibrosis and cirrhosis in chronic hepatitis C." | 7.74 | 13C-methacetin-breath test compared to also noninvasive biochemical blood tests in predicting hepatic fibrosis and cirrhosis in chronic hepatitis C. ( Braden, B; Caspary, WF; Chapman, RW; Dietrich, CF; Dinesen, L; Sarrazin, C, 2008) |
| "Sixty-one healthy controls and 81 patients with chronic hepatitis C underwent a 13C-methacetin breath test." | 7.73 | 13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection. ( Braden, B; Caspary, WF; Dietrich, CF; Faust, D; Sarrazin, C; Sarrazin, U; Zeuzem, S, 2005) |
| "20 healthy volunteers (ten women, ten men, aged 22-76 years) and 16 patients (ten women, six men, aged 48-71 years) with histologically confirmed liver cirrhosis (Child-Pugh stage A [n = 7], B [n = 5] or C [n = 4]) were given 13C-methacetin in 100 ml of tea after a 12-hour fasting period." | 7.70 | [The 13C-methacetin breath test for quantitative noninvasive liver function analysis with an isotope-specific nondispersive infrared spectrometer in liver cirrhosis]. ( Adamek, RJ; Götze, O; Hagemann, D; Pfaffenbach, B; Szymanski, C, 1998) |
| "Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in many parts of the world." | 5.39 | The role of ¹³C-methacetin breath test for the non-invasive evaluation of nonalcoholic fatty liver disease. ( Braticevici, B; Fierbinteanu-Braticevici, C; Panaitescu, E; Plesca, DA; Tribus, L, 2013) |
| " The present study was carried out to evaluate the role of 13C-methacetin breath test 13C-MBT) as a non invasive tool for liver fibrosis staging in patients with chronic hepatitis C (CHC)." | 5.19 | Role of 13C methacetin breath test for non invasive staging of liver fibrosis in patients with chronic hepatitis C. ( Cristian, B; Fierbinteanu-Braticevici, C; Papacocea, R; Tribus, L, 2014) |
| "Overweight, obesity and liver fat accumulation manifest with deranged portal extraction efficiency of methacetin into the steatotic hepatocyte." | 4.31 | Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease. ( Andrade, R; Bonfrate, L; Di Ciaula, A; Macedo, MP; Pina, A; Portincasa, P; Raposo, JF; Ribeiro, R; Shanmugam, H, 2023) |
| "In this pilot study, methacetin breath testing predicted the risk of liver-related death and development/exacerbation of ascites more accurately than MELD ⩾15 or ⩾19." | 3.81 | Use of the methacetin breath test to classify the risk of cirrhotic complications and mortality in patients evaluated/listed for liver transplantation. ( Brown, K; Gordon, SC; Ilan, Y; Lalazar, G; Mizrahi, M; Reuben, A; Sanyal, A; Stravitz, RT, 2015) |
| "The non-invasive (13)C-methacetin ((13)C-MBT) breath test has been proposed as a measure of metabolic liver function that improves the diagnostic efficacy of serologic and biochemical tests in assessing hepatic functional capacity and liver disease severity, The goal of this study was to establish the clinical utility of this test in quantifying hepatic metabolic function in patients with liver cirrhosis of varying severity and to compare (13)C-MBT measurements with the AST/ALT ratio, APRI score, and other routine liver tests." | 3.79 | ¹³C-methacetin breath test in the evaluation of disease severity in patients with liver cirrhosis. ( Hendrichova, M; Horak, J; Kolarova, H; Kratka, K; Rosina, J; Vranova, J, 2013) |
| " A methionine-choline deficient diet was used for the induction of fatty liver." | 3.74 | Utility of a 13C-methacetin breath test in evaluating hepatic injury in rats. ( Aeed, H; Avni, Y; Ilan, Y; Shahmurov, M; Shalev, T; Shirin, H; Sorin, V; Stavinski, S, 2008) |
| "The (13)C-methacetin-breath test and also several noninvasive blood tests comprising routine laboratory parameters have been proposed to predict fibrosis and cirrhosis in chronic hepatitis C." | 3.74 | 13C-methacetin-breath test compared to also noninvasive biochemical blood tests in predicting hepatic fibrosis and cirrhosis in chronic hepatitis C. ( Braden, B; Caspary, WF; Chapman, RW; Dietrich, CF; Dinesen, L; Sarrazin, C, 2008) |
| "Sixty-one healthy controls and 81 patients with chronic hepatitis C underwent a 13C-methacetin breath test." | 3.73 | 13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection. ( Braden, B; Caspary, WF; Dietrich, CF; Faust, D; Sarrazin, C; Sarrazin, U; Zeuzem, S, 2005) |
| "20 healthy volunteers (ten women, ten men, aged 22-76 years) and 16 patients (ten women, six men, aged 48-71 years) with histologically confirmed liver cirrhosis (Child-Pugh stage A [n = 7], B [n = 5] or C [n = 4]) were given 13C-methacetin in 100 ml of tea after a 12-hour fasting period." | 3.70 | [The 13C-methacetin breath test for quantitative noninvasive liver function analysis with an isotope-specific nondispersive infrared spectrometer in liver cirrhosis]. ( Adamek, RJ; Götze, O; Hagemann, D; Pfaffenbach, B; Szymanski, C, 1998) |
| "Methacetin breath test was correlated with liver function tests and serum bile acids." | 2.71 | Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels. ( Capodicasa, S; Colaiocco-Ferrante, L; Colecchia, A; Festi, D; Mazzella, G; Portincasa, P; Roda, E; Sandri, L; Simoni, P; Staniscia, T; Vestito, A; Vitacolonna, E, 2005) |
| "Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in many parts of the world." | 1.39 | The role of ¹³C-methacetin breath test for the non-invasive evaluation of nonalcoholic fatty liver disease. ( Braticevici, B; Fierbinteanu-Braticevici, C; Panaitescu, E; Plesca, DA; Tribus, L, 2013) |
| "For the diagnosis of liver cirrhosis and correlations with liver fibrosis, the accuracy of the PBT at 30 min (PBT30) was similar to that of the MethaBT at 15 min (Metha15)." | 1.38 | Liver function assessment with three (13)C breath tests by two-point measurements. ( Asai, S; Ishii, Y; Murai, I; Suzuki, S, 2012) |
| "Chronic viral hepatitis B and C cause liver fibrosis, leading to cirrhosis." | 1.37 | Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients. ( de Knegt, RJ; Francke, J; Hansen, BE; Kuipers, EJ; Stibbe, KJ; van Vuuren, AJ; Verveer, C; Zondervan, PE, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.89) | 18.7374 |
| 1990's | 3 (8.33) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 12 (33.33) | 24.3611 |
| 2020's | 4 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Di Ciaula, A | 2 |
| Shanmugam, H | 2 |
| Ribeiro, R | 1 |
| Pina, A | 1 |
| Andrade, R | 1 |
| Bonfrate, L | 2 |
| Raposo, JF | 1 |
| Macedo, MP | 1 |
| Portincasa, P | 3 |
| Weber, SN | 1 |
| Krawczyk, M | 1 |
| Makridis, G | 1 |
| Oldhafer, KJ | 1 |
| Sklyarova, HE | 1 |
| Lock, JF | 1 |
| Westphal, T | 1 |
| Rubin, T | 1 |
| Malinowski, M | 2 |
| Schulz, A | 1 |
| Jara, M | 2 |
| Bednarsch, J | 1 |
| Stockmann, M | 3 |
| Moran, S | 1 |
| Mina, A | 1 |
| Duque, X | 1 |
| Ortiz-Olvera, N | 1 |
| Rodriguez-Leal, G | 1 |
| Alfredo Sierra-Ramírez, J | 1 |
| Medina-Santillán, R | 1 |
| Mera, RM | 1 |
| Uribe, M | 1 |
| Buechter, M | 1 |
| Thimm, J | 1 |
| Baba, HA | 1 |
| Bertram, S | 1 |
| Willuweit, K | 1 |
| Gerken, G | 1 |
| Kahraman, A | 1 |
| Dziodzio, T | 1 |
| Lüttgert, K | 1 |
| Nikolov, R | 1 |
| Ritschl, PV | 1 |
| Öllinger, R | 1 |
| Pratschke, J | 2 |
| Heucke, N | 1 |
| Wuensch, T | 1 |
| Mohr, J | 1 |
| Kaffarnik, M | 1 |
| Arsenic, R | 1 |
| Sinn, B | 1 |
| Müller, T | 1 |
| Sack, I | 1 |
| Tzschätzsch, H | 1 |
| Vranova, J | 1 |
| Hendrichova, M | 1 |
| Kolarova, H | 1 |
| Kratka, K | 1 |
| Rosina, J | 1 |
| Horak, J | 1 |
| Kochel-Jankowska, A | 1 |
| Hartleb, M | 1 |
| Jonderko, K | 1 |
| Kaminska, M | 1 |
| Kasicka-Jonderko, A | 1 |
| Fierbinteanu-Braticevici, C | 2 |
| Plesca, DA | 1 |
| Tribus, L | 2 |
| Panaitescu, E | 1 |
| Braticevici, B | 1 |
| Papacocea, R | 1 |
| Cristian, B | 1 |
| Stravitz, RT | 1 |
| Reuben, A | 1 |
| Mizrahi, M | 1 |
| Lalazar, G | 2 |
| Brown, K | 1 |
| Gordon, SC | 1 |
| Ilan, Y | 3 |
| Sanyal, A | 1 |
| Pappo, O | 1 |
| Hershcovici, T | 1 |
| Hadjaj, T | 1 |
| Shubi, M | 1 |
| Ohana, H | 1 |
| Hemed, N | 1 |
| Shirin, H | 1 |
| Aeed, H | 1 |
| Shalev, T | 1 |
| Sorin, V | 1 |
| Stavinski, S | 1 |
| Shahmurov, M | 1 |
| Avni, Y | 1 |
| Stibbe, KJ | 1 |
| Verveer, C | 1 |
| Francke, J | 1 |
| Hansen, BE | 1 |
| Zondervan, PE | 1 |
| Kuipers, EJ | 1 |
| de Knegt, RJ | 1 |
| van Vuuren, AJ | 1 |
| Ishii, Y | 1 |
| Suzuki, S | 1 |
| Asai, S | 1 |
| Murai, I | 1 |
| Zipprich, A | 1 |
| Meiss, F | 1 |
| Steudel, N | 1 |
| Sziegoleit, U | 1 |
| Fleig, WE | 1 |
| Kleber, G | 1 |
| Petrolati, A | 1 |
| Festi, D | 2 |
| De Berardinis, G | 1 |
| Colaiocco-Ferrante, L | 2 |
| Di Paolo, D | 1 |
| Tisone, G | 1 |
| Angelico, M | 1 |
| Candelli, M | 2 |
| Cazzato, IA | 1 |
| Nista, EC | 2 |
| Pignataro, G | 1 |
| Gasbarrini, A | 2 |
| Armuzzi, A | 1 |
| Fini, L | 1 |
| Gasbarrini, G | 1 |
| Capodicasa, S | 1 |
| Sandri, L | 1 |
| Staniscia, T | 1 |
| Vitacolonna, E | 1 |
| Vestito, A | 1 |
| Simoni, P | 1 |
| Mazzella, G | 1 |
| Roda, E | 1 |
| Colecchia, A | 1 |
| Braden, B | 3 |
| Faust, D | 1 |
| Sarrazin, U | 1 |
| Zeuzem, S | 1 |
| Dietrich, CF | 3 |
| Caspary, WF | 3 |
| Sarrazin, C | 3 |
| Liu, YX | 1 |
| Huang, LY | 1 |
| Wu, CR | 1 |
| Cui, J | 1 |
| Schneider, A | 1 |
| Saich, R | 1 |
| Kuker, W | 1 |
| Goetze, O | 2 |
| Selzner, N | 1 |
| Fruehauf, H | 1 |
| Fried, M | 1 |
| Gerlach, T | 1 |
| Mullhaupt, B | 1 |
| Dinesen, L | 1 |
| Chapman, RW | 1 |
| Klein, PD | 1 |
| Klatt, S | 1 |
| Taut, C | 1 |
| Mayer, D | 1 |
| Adler, G | 1 |
| Beckh, K | 1 |
| Pfaffenbach, B | 2 |
| Götze, O | 1 |
| Szymanski, C | 1 |
| Hagemann, D | 1 |
| Adamek, RJ | 2 |
| Boedeker, C | 1 |
| Luypaerts, A | 1 |
| Geypens, B | 1 |
| Matsumoto, K | 1 |
| Suehiro, M | 1 |
| Iio, M | 1 |
| Kawabe, T | 1 |
| Shiratori, Y | 1 |
| Okano, K | 1 |
| Sugimoto, T | 1 |
| Qiu, YY | 1 |
| Tang, ZD | 2 |
| Xia, ZQ | 1 |
| Dai, TC | 1 |
| Hu, YE | 1 |
| Li, J | 1 |
| Lu, YJ | 1 |
| Zhang, NL | 1 |
| Qiu, YQ | 1 |
| Krumbiegel, P | 1 |
| Günther, K | 1 |
| Faust, H | 1 |
| Möbius, G | 1 |
| Hirschberg, K | 1 |
| Schneider, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 13C-Methacetin Breath Test for the Prediction of Outcome in in Acute Liver Injury or Acute Liver Failure[NCT02786836] | Phase 2/Phase 3 | 76 participants (Actual) | Interventional | 2016-06-10 | Completed | ||
| Development of a Breath Test for Monitoring Liver Metabolic Function in Patients With Chronic Liver Disease and Cirrhosis[NCT00244569] | Phase 3 | 120 participants (Anticipated) | Interventional | 2005-09-30 | Completed | ||
| Pilot Study to Evaluate the Correlation Between ¹³C Methacetin Breath Test (MBT) and HVPG Measurement as a Tool for Identifying Responders to Portal Hypertension Therapy[NCT01851252] | Phase 1 | 19 participants (Actual) | Interventional | 2013-10-31 | Completed | ||
| Use of the BreathID to Assess Hepatic Metabolic Reserve and to Predict Hepatic Decompensation in Patients With Cirrhosis in Need of Liver Transplantation[NCT00375011] | 200 participants (Anticipated) | Observational | 2008-09-30 | Terminated (stopped due to Company restructured and protocol restructured. Resubmitted with IDE approval under new company name-Exalenz) | |||
| Methacetin Breath Test in HCV Patients With Normal and Near-Normal ALT[NCT00294489] | 500 participants (Anticipated) | Observational | 2006-02-28 | Recruiting | |||
| Use of the BreathID Methacetin Breath Test to Assess Hepatic Metabolic Reserve and to Predict Hepatic Decompensation in Patients Awaiting Liver Transplantation[NCT01157845] | Phase 3 | 165 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The relationship between the cPDR (cumulative PDR of metabolized 13C-Methacetin 20 minutes after ingestion) in single time points of MBT measurements and TFS and non-TFS (death/transplant) at Day 21. (NCT02786836)
Timeframe: The first MBT reading either on Day 1 or Day 2 and Day 21
| Intervention | percentage per hour (Mean) | |
|---|---|---|
| Day 1 or 2 MBT/transplant free survival at Day 21 | Day 1 or 2 MBT & Day 21 non-TFS | |
| 13C-Methacetin Breath Test (MBT) | 1.4 | 0.2 |
Peak PDR is the maximal percent dose recovery (PDR) rate which reflects the maximum rate of metabolism of 13C-methacetin measured as the change in 13CO2 / 12CO2 (normal carbon dioxide) ratio after ingestion of 13C-methacetin normalized using the patient's height and weight. The distributions of mean PDR Peak values were compared between TFS (transplant free survival) and non-TFS (death/transplant) at Day 21. (NCT02786836)
Timeframe: Days 1 and 21
| Intervention | percentage per hour (Mean) | |
|---|---|---|
| Mean Peak PDR for TFS subjects at Day 21 | Mean Peak PDR for non-TFS subjects at Day 21 | |
| 13C-Methacetin Breath Test (MBT) | 10.2 | 1.9 |
This outcome is similar to the peak PDR defined in the primary outcome but as a secondary we are looking at Day 1 or Day 2 peak PDR values. Peak PDR is the maximal percent dose recovery (PDR) rate which reflects the maximum rate of metabolism of 13C-methacetin measured as the change in 13CO2 / 12CO2 ratio after ingestion of 13C-methacetin normalized using the patient's height and weight. The distributions of mean PDR Peak values were compared between TFS and non-TFS (death/transplant) at Day 21. (NCT02786836)
Timeframe: The first MBT reading either on Day 1 or Day 2 and Day 21
| Intervention | percentage per hour (Mean) | |
|---|---|---|
| Day 1 or 2 MBT & Day 21 TFS | Day 1 or 2 MBT & Day 21 non-TFS | |
| 13C-Methacetin Breath Test (MBT) | 9.1 | 2.3 |
Patient experiences complications of liver failure within 1 year of study entry and undergoes liver transplantation (NCT01157845)
Timeframe: 1 year
| Intervention | participants (Number) |
|---|---|
| Laboratory Assay | 34 |
Patient dies of liver-related causes within 1 year of study entry (NCT01157845)
Timeframe: 1 year
| Intervention | participants (Number) |
|---|---|
| Laboratory Assay | 11 |
3 trials available for methacetin and Liver Cirrhosis
| Article | Year |
|---|---|
Role of 13C methacetin breath test for non invasive staging of liver fibrosis in patients with chronic hepatitis C.
Topics: Acetamides; Area Under Curve; Breath Tests; Carbon Isotopes; Enzyme-Linked Immunosorbent Assay; Fema | 2014 |
13C-methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation.
Topics: Acetamides; Adult; Breath Tests; Female; Humans; Intraoperative Care; Liver Cirrhosis; Liver Functio | 2003 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Breath Tests; Carbon Isotopes; Fem | 2005 |
33 other studies available for methacetin and Liver Cirrhosis
| Article | Year |
|---|---|
Liver fat accumulation more than fibrosis causes early liver dynamic dysfunction in patients with non-alcoholic fatty liver disease.
Topics: Biomarkers; Diabetes Mellitus, Type 2; Humans; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Dis | 2023 |
Effects of MBOAT7 polymorphism and steatosis on liver function assessed by methacetin breath test.
Topics: Acyltransferases; Humans; Liver; Liver Cirrhosis; Membrane Proteins; Non-alcoholic Fatty Liver Disea | 2023 |
First intraoperative measurement of liver functional capacity during liver surgery using the
Topics: Acetamides; Breath Tests; Follow-Up Studies; Hepatectomy; Liver; Liver Cirrhosis; Liver Function Tes | 2020 |
13C-METHACETIN BREATHE TEST IN EARLY DIAGNOSTICS OF NON-ALCOHOLIC FATTY LIVER DISEASE.
Topics: Acetamides; Breath Tests; Carbon Isotopes; Female; Humans; Liver Cirrhosis; Male; Non-alcoholic Fatt | 2021 |
LiMAx Test Improves Diagnosis of Chemotherapy-Associated Liver Injury Before Resection of Colorectal Liver Metastases.
Topics: Acetamides; Aged; Algorithms; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Chemoth | 2017 |
The utility of the
Topics: Acetamides; Breath Tests; Carbon Isotopes; Demography; Female; Humans; Liver Cirrhosis; Male; Middle | 2017 |
Liver Maximum Capacity: A Novel Test to Accurately Diagnose Different Stages of Liver Fibrosis.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Aspartate Aminotransfe | 2019 |
Prospective Assessment of Liver Function by an Enzymatic Liver Function Test to Estimate Short-Term Survival in Patients with Liver Cirrhosis.
Topics: Acetamides; Breath Tests; Carbon Dioxide; Carbon Isotopes; Cohort Studies; Creatinine; Cytochrome P- | 2019 |
Non-invasive structure-function assessment of the liver by 2D time-harmonic elastography and the dynamic Liver MAximum capacity (LiMAx) test.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Aspartate Aminotransferases; Carbon Isotopes; Case-Contr | 2019 |
¹³C-methacetin breath test in the evaluation of disease severity in patients with liver cirrhosis.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Breath Tests; Carbon Isotopes; Female; Humans; Liver Cir | 2013 |
13C-methacetin breath test correlates with clinical indices of liver disease severity in patients with primary biliary cirrhosis.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Isotopes; Case-Control Studies; Cytochrome P-450 Enzym | 2013 |
The role of ¹³C-methacetin breath test for the non-invasive evaluation of nonalcoholic fatty liver disease.
Topics: Acetamides; Adult; Analysis of Variance; Area Under Curve; Biomarkers; Biopsy; Breath Tests; Carbon | 2013 |
Use of the methacetin breath test to classify the risk of cirrhotic complications and mortality in patients evaluated/listed for liver transplantation.
Topics: Acetamides; Aged; Ascites; Breath Tests; End Stage Liver Disease; Female; Humans; Liver Cirrhosis; L | 2015 |
A continuous 13C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT.
Topics: Acetamides; Adult; Aged; Alanine Transaminase; Algorithms; Breath Tests; Carbon Isotopes; Female; He | 2008 |
Utility of a 13C-methacetin breath test in evaluating hepatic injury in rats.
Topics: Acetamides; Administration, Oral; Animals; Breath Tests; Carbon Isotopes; Choline Deficiency; Diseas | 2008 |
Comparison of non-invasive assessment to diagnose liver fibrosis in chronic hepatitis B and C patients.
Topics: Acetamides; Adult; Aspartate Aminotransferases; Biomarkers; Blood Platelets; Breath Tests; Elasticit | 2011 |
Liver function assessment with three (13)C breath tests by two-point measurements.
Topics: Acetamides; Aged; Breath Tests; Carbon Dioxide; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; | 2012 |
13C-Methacetin metabolism in patients with cirrhosis: relation to disease severity, haemoglobin content and oxygen supply.
Topics: Acetamides; Breath Tests; Female; Hemoglobins; Humans; Hypoxia; Liver; Liver Cirrhosis; Male; Middle | 2003 |
13C-methacetin breath test and oxygen supply.
Topics: Acetamides; Administration, Inhalation; Breath Tests; Liver; Liver Cirrhosis; Oxygen | 2003 |
13C-methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation.
Topics: Acetamides; Breath Tests; Humans; Liver Cirrhosis; Liver Function Tests; Liver Transplantation | 2004 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
13C-methacetin breath test as liver function test in patients with chronic hepatitis C virus infection.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Case-Control Studies; Female; Hepatitis | 2005 |
Measurement of liver function for patients with cirrhosis by 13C-methacetin breath test compared with Child-Pugh score and routine liver function tests.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Isotopes; Female; Humans; Liver Cirrhosis; Liver Funct | 2006 |
13C-methacetin breath test shortened: 2-point-measurements after 15 minutes reliably indicate the presence of liver cirrhosis.
Topics: Acetamides; Adult; Aged; Biopsy; Breath Tests; Carbon Isotopes; Cytochrome P-450 Enzyme System; Fema | 2007 |
13C-methacetin breath test as a quantitative liver function test in patients with chronic hepatitis C infection: continuous automatic molecular correlation spectroscopy compared to isotopic ratio mass spectrometry.
Topics: Acetamides; Adult; Breath Tests; Carbon Isotopes; Female; Hepatitis C, Chronic; Humans; Liver Cirrho | 2007 |
13C-methacetin breath test as a quantitative liver function test in patients with chronic hepatitis C infection: continuous automatic molecular correlation spectroscopy compared to isotopic ratio mass spectrometry.
Topics: Acetamides; Adult; Breath Tests; Carbon Isotopes; Female; Hepatitis C, Chronic; Humans; Liver Cirrho | 2007 |
13C-methacetin breath test as a quantitative liver function test in patients with chronic hepatitis C infection: continuous automatic molecular correlation spectroscopy compared to isotopic ratio mass spectrometry.
Topics: Acetamides; Adult; Breath Tests; Carbon Isotopes; Female; Hepatitis C, Chronic; Humans; Liver Cirrho | 2007 |
13C-methacetin breath test as a quantitative liver function test in patients with chronic hepatitis C infection: continuous automatic molecular correlation spectroscopy compared to isotopic ratio mass spectrometry.
Topics: Acetamides; Adult; Breath Tests; Carbon Isotopes; Female; Hepatitis C, Chronic; Humans; Liver Cirrho | 2007 |
13C-methacetin-breath test compared to also noninvasive biochemical blood tests in predicting hepatic fibrosis and cirrhosis in chronic hepatitis C.
Topics: Acetamides; Adult; Aged; Biopsy, Needle; Breath Tests; Cohort Studies; Disease Progression; Female; | 2008 |
Clinical applications of 13CO2 measurements.
Topics: Acetamides; Amino Acids; Aminopyridines; Animals; Breath Tests; Carbon Dioxide; Carbon Isotopes; Dig | 1982 |
Evaluation of the 13C-methacetin breath test for quantitative liver function testing.
Topics: Acetamides; Adult; Aged; Breath Tests; Carbon Radioisotopes; Female; Hepatitis, Viral, Human; Humans | 1997 |
[The 13C-methacetin breath test for quantitative noninvasive liver function analysis with an isotope-specific nondispersive infrared spectrometer in liver cirrhosis].
Topics: Acetamides; Aged; Analysis of Variance; Breath Tests; Carbon Isotopes; Evaluation Studies as Topic; | 1998 |
13C-methacetin breath test: isotope-selective nondispersive infrared spectrometry in comparison to isotope ratio mass spectrometry in volunteers and patients with liver cirrhosis.
Topics: Acetamides; Adult; Aged; Carbon Isotopes; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tes | 1999 |
[13C]methacetin breath test for evaluation of liver damage.
Topics: Acetamides; Adult; Breath Tests; Carbon Dioxide; Carcinoma, Hepatocellular; Female; Humans; Liver Ci | 1987 |
Diagnostic value of C-13-methacetin breath test in liver diseases.
Topics: Acetamides; Breath Tests; Carbon Isotopes; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosi | 1988 |
[Assessment of liver function with the 13C methacetin breath test].
Topics: Acetamides; Adolescent; Adult; Breath Tests; Carbon Isotopes; Female; Hepatitis, Chronic; Humans; Li | 1986 |
Nuclear medicine liver function tests for pregnant women and children. 1. Breath tests with 14C-methacetin and 13C-methacetin.
Topics: Acetamides; Breath Tests; Carbon Isotopes; Carbon Radioisotopes; Child; Female; Humans; Liver; Liver | 1985 |