Page last updated: 2024-12-10
glyceryl monothioglycolate
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
glyceryl monothioglycolate : A thioglycolate ester resulting from esterification of thioglycolic acid with glycerol. As a component of developer solutions in permanent wave products, it is the second most frequent allergen in hairdressers and avoidance of acid permanent waves is mandatory. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 3034372 |
| CHEBI ID | 156545 |
| SCHEMBL ID | 107724 |
| MeSH ID | M0104562 |
Synonyms (37)
| Synonym |
|---|
| mercaptoacetic acid, monoester with propane-1,2,3-triol |
| glycerol monomercaptoacetate |
| acetic acid, mercapto-, monoester with glycerol |
| glyceryl thioglycolate |
| mercaptoacetic acid, monoester with 1,2,3-propanetriol |
| glyceryl monothioglycolate |
| einecs 250-264-8 |
| acetic acid, mercapto-, monoester with 1,2,3-propanetriol |
| 30618-84-9 |
| CHEBI:156545 |
| 2,3-dihydroxypropyl sulfanylacetate |
| FT-0651643 |
| 2,3-dihydroxypropyl 2-sulfanylacetate |
| AKOS006274928 |
| ec 250-264-8 |
| unii-0fwe72af2p |
| acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol |
| 0fwe72af2p , |
| glyceryl 1-thioglycolate |
| glycerol 1-monothioglycolate |
| 0A100Y3J61 , |
| acetic acid, 2-mercapto-, 2,3-dihydroxypropyl ester |
| glyceryl 1-monothioglycolate |
| 68148-42-5 |
| SCHEMBL107724 |
| unii-0a100y3j61 |
| glycerol monomercaptoacetate, technical grade, 82% |
| mfcd00153007 |
| H10926 |
| glyceryl monothioglycolate, techincal grade |
| DOGJSOZYUGJVKS-UHFFFAOYSA-N |
| glycerol monothioglycolate |
| DTXSID60873439 |
| 2,3-dihydroxypropyl 2-mercaptoacetate |
| Q27236512 |
| glycerolmonomercaptoacetate |
| mercaptoacetic acid monoester with 1,2,3-propanetrio |
Research Excerpts
Effects
| Excerpt | Reference | Relevance |
|---|---|---|
| "Glyceryl monothioglycolate has recently been implicated as an allergen. " | ( Irritant contact dermatitis to glyceryl monothioglycolate. Rapaport, M, 1983) | 1.99 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Roles (1)
| Role | Description |
|---|---|
| allergen | A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Drug Classes (1)
| Class | Description |
|---|---|
| thioglycolate ester | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Research
Studies (20)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 35.12
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (35.12) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 8 (36.36%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 14 (63.64%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||