glyceryl monothioglycolate : A thioglycolate ester resulting from esterification of thioglycolic acid with glycerol. As a component of developer solutions in permanent wave products, it is the second most frequent allergen in hairdressers and avoidance of acid permanent waves is mandatory. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 3034372 |
| CHEBI ID | 156545 |
| SCHEMBL ID | 107724 |
| MeSH ID | M0104562 |
| Synonym |
|---|
| mercaptoacetic acid, monoester with propane-1,2,3-triol |
| glycerol monomercaptoacetate |
| acetic acid, mercapto-, monoester with glycerol |
| glyceryl thioglycolate |
| mercaptoacetic acid, monoester with 1,2,3-propanetriol |
| glyceryl monothioglycolate |
| einecs 250-264-8 |
| acetic acid, mercapto-, monoester with 1,2,3-propanetriol |
| 30618-84-9 |
| CHEBI:156545 |
| 2,3-dihydroxypropyl sulfanylacetate |
| FT-0651643 |
| 2,3-dihydroxypropyl 2-sulfanylacetate |
| AKOS006274928 |
| ec 250-264-8 |
| unii-0fwe72af2p |
| acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol |
| 0fwe72af2p , |
| glyceryl 1-thioglycolate |
| glycerol 1-monothioglycolate |
| 0A100Y3J61 , |
| acetic acid, 2-mercapto-, 2,3-dihydroxypropyl ester |
| glyceryl 1-monothioglycolate |
| 68148-42-5 |
| SCHEMBL107724 |
| unii-0a100y3j61 |
| glycerol monomercaptoacetate, technical grade, 82% |
| mfcd00153007 |
| H10926 |
| glyceryl monothioglycolate, techincal grade |
| DOGJSOZYUGJVKS-UHFFFAOYSA-N |
| glycerol monothioglycolate |
| DTXSID60873439 |
| 2,3-dihydroxypropyl 2-mercaptoacetate |
| Q27236512 |
| glycerolmonomercaptoacetate |
| mercaptoacetic acid monoester with 1,2,3-propanetrio |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Glyceryl monothioglycolate has recently been implicated as an allergen. " | ( Irritant contact dermatitis to glyceryl monothioglycolate. Rapaport, M, 1983) | 1.99 |
| Role | Description |
|---|---|
| allergen | A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| thioglycolate ester | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 10 (50.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 3 (15.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.
| This Compound (35.12) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 8 (36.36%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 14 (63.64%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||