Compounds > coronatine
Page last updated: 2024-09-24

coronatine

Description

coronatine: consists of a coronafacic acid joined by an amide bond to coronamic acid by coronafacate ligase; phytotoxin produced by Pseudomonas syringae; RN given refers to (3aS-(3aalpha,4(1R*,2R*),6beta,7alpha))-isomer; [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID91681
CHEBI ID80730
MeSH IDM0163078

Synonyms (16)

Synonym
coronatine
62251-96-1
(1s,2s)-1-[[(3as,6r,7as)-6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydroindene-4-carbonyl]amino]-2-ethylcyclopropane-1-carboxylic acid
unii-wcr4xue8vb
cyclopropanecarboxylic acid, 2-ethyl-1-(((6-ethyl-2,3,3a,6,7,7a-hexahydro-1-oxo-1h-inden-4-yl)carbonyl)amino)-
wcr4xue8vb ,
CHEBI:80730
Q5172198
DTXSID20977826
(+)-coronatine
CS-0646203
cyclopropanecarboxylic acid, 2-ethyl-1-[[[(3as,6r,7as)-6-ethyl-2,3,3a,6,7,7a-hexahydro-1-oxo-1h-inden-4-yl]carbonyl]amino]-, (1s,2s)-
coronatine, (+)-
cyclopropanecarboxylic acid, 2-ethyl-1-[[(6-ethyl-2,3,3a,6,7,7a-hexahydro-1-oxo-1h-inden-4-yl)carbonyl]amino]-, [3as-[3aalpha,4(1r*,2r*),6beta,7aalpha]]-
(1s,2s)-2-ethyl-1-[[[(3as,6r,7as)-6-ethyl-2,3,3a,6,7,7a-hexahydro-1-oxo-1h-inden-4-yl]carbonyl]amino]cyclopropanecarboxylic acid
HY-N11420

Research Excerpts

Overview

ExcerptReference
"Coronatine is a toxin produced by the bacterial pathogen Pseudomonas syringae that is known to counteract Arabidopsis defense through mimicking defense signaling molecules, jasmonates (JAs)."( Gao, M; Lu, H; Zhang, C, 2020)
"Coronatine (COR) is a non-host specific phytotoxin secreted by Pseudomonas syringae pv. "( Afzal, AJ; Geng, XQ; He, B; Li, T; Sun, S; Wang, HH; Xu, LR; Zhang, X; Zhang, ZC, 2021)
"Coronatine (COR), which is a phytotoxin and produced by the pathogen Pseudomonas syringae, is a functional and structural analogue of jasmonic acid (JA)."( Duan, L; Guo, Q; Huang, G; Li, Y; Li, Z; Ren, Z; Tao, Q; Wang, X; Yi, F; Zhang, M; Zhou, Y, 2021)
"Coronatine (COR) is a phytotoxin produced by Pseudomonas syringae. "( Duan, L; Li, J; Li, X; Li, Z; Liu, Y; Peng, C; Tian, X; Zhang, M; Zhou, Y, 2018)
"Coronatine (COR) is a structural and functional analog of methyl jasmonic acid (MeJA), which can alleviate stress on plant. "( Ai, L; Duan, L; Gao, W; Yu, C; Zhou, Y, 2019)
"Coronatine (COR) is a chlorosis-inducing non-host-specific phytotoxin that induces leaf and/or fruit abscission in some crops."( Du, M; Duan, L; Li, Y; Li, Z; Tan, W; Tian, X; Xu, D; Zhang, M, 2014)
"Coronatine (COR) is a bacterial phytotoxin that functionally mimics JA-Ile and interacts with the COI1-JAZ co-receptor with higher affinity than JA-Ile."( Boter, M; Chini, A; García-Casado, G; Gimenez-Ibanez, S; Hamberg, M; Monte, I; Pazos, F; Porzel, A; Solano, R, 2014)
"Coronatine [COR] is a novel type of plant growth regulator with similarities in structure and property to jasmonate. "( Hu, Z; Wang, Q; Wang, S; Wang, X; Zhang, B; Zhang, J; Zhang, X; Zhang, Z, 2015)
"Coronatine (COR) is a phytotoxin produced by Pseudomonas syringae. "( Duan, L; Li, J; Li, Z; Tian, X; Zhang, M; Zhou, Y, 2015)
"Coronatine is an important virulence factor produced by several pathovars of the bacterial pathogen Pseudomonas syringae. "( Browse, J; Chung, HS; He, SY; Howe, GA; Katsir, L; Mecey, C; Melotto, M; Niu, Y; Staswick, P; Thines, B; Yao, J; Zeng, W, 2008)
"Coronatine is a toxin produced by the pathogen Pseudomonas syringae. "( Bonfill, M; Cusidó, RM; Goossens, A; Moyano, E; Onrubia, M; Palazón, J, 2013)
"Coronatine (COR) is a chlorosis-inducing phytotoxin produced by the plant-pathogenic bacterium Pseudomonas syringae. "( Schenk, A; Stubner, S; Ullrich, MS; Weingart, H, 2004)
"Coronatine (COR) is a phytotoxin produced by several pathovars of Pseudomonas syringae and consists of coronafacic acid (CFA), an analog of methyl jasmonic acid (MeJA), and coronamic acid (CMA), which resembles 1-aminocyclopropane-1-carboxylic acid (ACC), a precursor to ethylene. "( Ayoubi, P; Bender, CL; Jones, W; Mitchell, RE; Palmer, DA; Uppalapati, SR; Weng, H, 2005)
"Coronatine (COR) is a chlorosis-inducing phytotoxin that mimics some biological activities of methyl jasmonate. "( Duan, L; Eneji, AE; Li, Z; Tian, X; Wang, B; Xie, Z, 2008)
"Coronatine is a phytotoxin produced by some plant-pathogenic bacteria. "( Arruda, P; Benedetti, CE; Costa, CL; Turcinelli, SR, 1998)
"Coronatine (COR) is a plasmid-encoded phytotoxin synthesized by several pathovars of phytopathogenic Pseudomonas syringae. "( Bender, CL; Peñaloza-Vázquez, A, 1998)
"Coronatine (COR) is a nonhost-specific phytotoxin that substantially contributes to the virulence of several pathovars (pvs.) of Pseudomonas syringae. "( Alarcón-Chaidez, FJ; Bender, CL; Peñaloza-Vázquez, A; Ullrich, M, 1999)

Treatment

ExcerptReference
"The coronatine treatment in L."( Choi, HK; Jeon, JY; Kim, DM; Kim, HY; Kim, JY; Lee, H; Lee, JS; Zhou, Y, 2017)
"Coronatine treatment of excised shoots caused increases in RNAs for jasmonic acid (JA)-regulated wound-response genes (LapA and pin2) but did not influence expression of a JA-regulated pathogenesis-related protein gene (PR-1)."( Chaufaux, J; Holzer, FM; Pautot, V; Walling, LL, 2001)

Drug Classes (1)

ClassDescription
N-acyl-amino acidA carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (196)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (0.51)18.7374
1990's25 (12.76)18.2507
2000's58 (29.59)29.6817
2010's80 (40.82)24.3611
2020's32 (16.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews9 (4.55%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other189 (95.45%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
jasmonic acid[no description available]medium580oxo monocarboxylic acidjasmonates;
plant metabolite
salicylic acid[no description available]medium250monohydroxybenzoic acidalgal metabolite;
antifungal agent;
antiinfective agent;
EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor;
keratolytic drug;
plant hormone;
plant metabolite
cyclopentane[no description available]medium730cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
methyl jasmonate[no description available]medium150
malondialdehyde[no description available]medium50dialdehydebiomarker
isoleucine[no description available]medium220aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
abscisic acid[no description available]medium1702-trans-abscisic acid
spermine[no description available]medium10polyazaalkane;
tetramine		antioxidant;
fundamental metabolite;
immunosuppressive agent
pyrophosphate[no description available]medium10diphosphate ion
artemisinin[no description available]medium10organic peroxide;
sesquiterpene lactone		antimalarial;
plant metabolite
phenyl acetate[no description available]medium140benzenes;
phenyl acetates
ferulic acid[no description available]medium10ferulic acidsanti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
MALDI matrix material;
plant metabolite
paclitaxel[no description available]medium40taxane diterpenoid;
tetracyclic diterpenoid		antineoplastic agent;
human metabolite;
metabolite;
microtubule-stabilising agent
gibberellins[no description available]medium10
betadex[no description available]medium20cyclodextrin
tabtoxin[no description available]medium20dipeptide;
L-threonine derivative;
monobactam;
secondary alcohol		bacterial metabolite;
toxin
syringomycin[no description available]medium20
coronafacic acid[no description available]medium120ketone
chlorophyll a[no description available]medium40chlorophyll;
methyl ester		cofactor
lignans[no description available]medium10
phaseolotoxin[no description available]medium20
ornithine[no description available]medium20non-proteinogenic L-alpha-amino acid;
ornithine		algal metabolite;
hepatoprotective agent;
mouse metabolite
beta carotene[no description available]medium10carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
1,1-diphenyl-2-picrylhydrazyl[no description available]medium20
beta-escin[no description available]medium10
ruscogenin[no description available]medium10triterpenoid
acetone[no description available]medium10ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
benzyl acetone[no description available]medium10ketone
nicotine[no description available]medium103-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
ethylene[no description available]medium70alkene;
gas molecular entity		plant hormone;
refrigerant
baccatin iii[no description available]medium20acetate ester;
benzoate ester;
tetracyclic diterpenoid		plant metabolite
gamma-aminobutyric acid[no description available]medium10amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid		human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule
pyoverdin[no description available]medium10
taxane[no description available]medium10diterpene;
terpenoid fundamental parent
10-deacetyltaxol[no description available]medium10
cephalomannine[no description available]medium10
isoprene[no description available]medium10alkadiene;
hemiterpene;
volatile organic compound		plant metabolite
phosphothreonine[no description available]medium10L-threonine derivative;
non-proteinogenic L-alpha-amino acid;
O-phosphoamino acid		Escherichia coli metabolite
resveratrol[no description available]medium10resveratrolantioxidant;
phytoalexin;
plant metabolite;
quorum sensing inhibitor;
radical scavenger
stilbenes[no description available]medium10stilbene
putrescine[no description available]medium10alkane-alpha,omega-diamineantioxidant;
fundamental metabolite
n-acetylputrescine[no description available]medium10N-monoacetylalkane-alpha,omega-diamine;
N-substituted putrescine		metabolite;
mouse metabolite
aethiopinone[no description available]medium10
naphthoquinones[no description available]medium10
methyl salicylate[no description available]medium10benzoate ester;
methyl ester;
salicylates		flavouring agent;
insect attractant;
metabolite
salicylates[no description available]medium10monohydroxybenzoateplant metabolite
1-amino-2-ethylcyclopropane-1-carboxylic acid[no description available]medium70amino monocarboxylic acid
biotin[no description available]medium10biotins;
vitamin B7		coenzyme;
cofactor;
Escherichia coli metabolite;
fundamental metabolite;
human metabolite;
mouse metabolite;
nutraceutical;
prosthetic group;
Saccharomyces cerevisiae metabolite
phytic acid[no description available]medium10inositol phosphate
azides[no description available]medium10pseudohalide anionmitochondrial respiratory-chain inhibitor
3-aminobutyric acid[no description available]medium10amino acid zwitterion;
beta-amino acid;
monocarboxylic acid		metabolite
benzo-1,2,3-thiadiazole[no description available]medium10
12-oxophytodienoic acid[no description available]medium40carbocyclic fatty acid;
olefinic fatty acid;
oxo carboxylic acid
indole[no description available]medium10indole;
polycyclic heteroarene		Escherichia coli metabolite
glucose, (beta-d)-isomer[no description available]medium20D-glucopyranoseepitope;
mouse metabolite
hexanoic acid[no description available]medium10medium-chain fatty acid;
straight-chain saturated fatty acid		human metabolite;
plant metabolite
pheophytin a[no description available]medium10
chlorophyll b[no description available]medium10chlorophyllcofactor
glyceollin[no description available]medium10organic heteropentacyclic compound
indoleacetic acid[no description available]medium20indole-3-acetic acids;
monocarboxylic acid		auxin;
human metabolite;
mouse metabolite;
plant hormone;
plant metabolite
adenosine monophosphate[no description available]medium10adenosine 5'-phosphate;
purine ribonucleoside 5'-monophosphate		adenosine A1 receptor agonist;
cofactor;
EC 3.1.3.1 (alkaline phosphatase) inhibitor;
EC 3.1.3.11 (fructose-bisphosphatase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
1-aminocyclopropane-1-carboxylic acid[no description available]medium10amino acid zwitterion;
monocarboxylic acid;
non-proteinogenic alpha-amino acid		ethylene releasers;
plant metabolite
Jasmone[no description available]medium10cyclic ketone
linalool[no description available]medium10monoterpenoid;
tertiary alcohol		antimicrobial agent;
fragrance;
plant metabolite;
volatile oil component
n(omega)-hydroxyarginine[no description available]medium10amino acid zwitterion;
N(5)-[(E)-amino(hydroxyimino)methyl]ornithine;
N(5)-[(hydroxyamino)(imino)methyl]ornithine;
N(5)-[(Z)-amino(hydroxyimino)methyl]ornithine;
N(5)-[amino(hydroxyimino)methyl]-L-ornithine;
N(5)-[amino(hydroxyimino)methyl]ornithine;
N(omega)-hydroxy-L-arginine
arginine[no description available]medium10arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
glucobrassicin[no description available]medium10indolyl carbohydrate;
indolylmethylglucosinolic acid
tryptophan[no description available]medium10erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
tryptophan zwitterion;
tryptophan		antidepressant;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
santalol[no description available]medium10
tetradecanal[no description available]medium102,3-saturated fatty aldehyde;
long-chain fatty aldehyde		bacterial metabolite;
plant metabolite
sesquiterpenes[no description available]medium20
tocopherols[no description available]medium10
chlorine[no description available]medium10diatomic chlorine;
gas molecular entity		bleaching agent
heme[no description available]medium10
valine[no description available]medium10L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid;
pyruvate family amino acid;
valine		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
berberine[no description available]medium10alkaloid antibiotic;
berberine alkaloid;
botanical anti-fungal agent;
organic heteropentacyclic compound		antilipemic drug;
antineoplastic agent;
antioxidant;
EC 1.1.1.141 [15-hydroxyprostaglandin dehydrogenase (NAD(+))] inhibitor;
EC 1.1.1.21 (aldehyde reductase) inhibitor;
EC 1.13.11.52 (indoleamine 2,3-dioxygenase) inhibitor;
EC 1.21.3.3 (reticuline oxidase) inhibitor;
EC 2.1.1.116 [3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase] inhibitor;
EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor;
EC 2.7.11.10 (IkappaB kinase) inhibitor;
EC 3.1.1.4 (phospholipase A2) inhibitor;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor;
EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
geroprotector;
hypoglycemic agent;
metabolite;
potassium channel blocker
leucine[no description available]medium10amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
acebutolol[no description available]medium10alpha-D-glucosyl-(1->4)-D-mannopyranose
cellulase[no description available]medium10cellotriose
alpha-linolenic acid[no description available]medium10linolenic acid;
omega-3 fatty acid		micronutrient;
mouse metabolite;
nutraceutical
mevalonic acid[no description available]medium103,5-dihydroxy-3-methylpentanoic acid
aspirin[no description available]medium10benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent
mocetinostat[no description available]medium10aminopyrimidine;
benzamides;
pyridines;
secondary amino compound;
secondary carboxamide;
substituted aniline		antineoplastic agent;
apoptosis inducer;
autophagy inducer;
cardioprotective agent;
EC 3.5.1.98 (histone deacetylase) inhibitor;
hepatotoxic agent
ethephon[no description available]medium10phosphonic acidsplant growth regulator
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
cycloheximide[no description available]medium10antibiotic fungicide;
cyclic ketone;
dicarboximide;
piperidine antibiotic;
piperidones;
secondary alcohol		anticoronaviral agent;
bacterial metabolite;
ferroptosis inhibitor;
neuroprotective agent;
protein synthesis inhibitor
cyclopentenone[no description available]medium10alicyclic ketone;
enone		Hsp70 inducer
thiorphan[no description available]low00N-acyl-amino acid
tiopronin[no description available]low00N-acyl-amino acid
citiolone[no description available]low00N-acyl-amino acid
n-phenylacetylphenylalanine[no description available]low00N-acyl-amino acid
stepronin[no description available]low00N-acyl-amino acid
gusperimus[no description available]low00N-acyl-amino acid
erdosteine[no description available]low00N-acyl-amino acid
st 679[no description available]low00N-acyl-amino acid
flomoxef[no description available]low00N-acyl-amino acid;
organonitrogen heterocyclic antibiotic;
oxacephem		antibacterial drug
n-benzoylalanine, (dl-ala)-isomer[no description available]low00alanine derivative;
N-acyl-amino acid		metabolite
palinavir[no description available]low00N-acyl-amino acid
racecadotril[no description available]low00N-acyl-amino acid
n-acetyl-s-(2-hydroxyethyl)cysteine[no description available]low00N-acyl-amino acid
n-acetyl-s-(n-methylcarbamoyl)cysteine[no description available]low00N-acyl-amino acid
sr 48692[no description available]low00N-acyl-amino acid
jstx-3[no description available]low00N-acyl-amino acid
argiotoxin-636[no description available]low00N-acyl-amino acid
ilomastat[no description available]low00hydroxamic acid;
L-tryptophan derivative;
N-acyl-amino acid		anti-inflammatory agent;
antibacterial agent;
antineoplastic agent;
EC 3.4.24.24 (gelatinase A) inhibitor;
neuroprotective agent
fr 120480[no description available]low00N-acyl-amino acid
philanthotoxin 343[no description available]low00N-acyl-amino acid
ceronapril[no description available]low00N-acyl-amino acid
succinylproline[no description available]low00N-acyl-amino acid
lacosamide[no description available]low00N-acyl-amino acid
1-Acetamidocyclopentanecarboxylic acid[no description available]low00N-acyl-amino acid
2-acetamido-2-(hydroxymethyl)propanedioic acid diethyl ester[no description available]low00N-acyl-amino acid
benzoylphenylalanine[no description available]low00benzamides;
N-acyl-amino acid
n-acetylproline[no description available]low00N-acyl-amino acid
plasminogen activator inhibitor 2[no description available]low00N-acyl-amino acid
n-heptanoyl-homoserine lactone[no description available]low00N-acyl-amino acid
Spicamycin[no description available]low00N-acyl-amino acid
1-[[(4-chloroanilino)-oxomethyl]amino]-N-[3-(4-morpholinyl)propyl]-1-cyclohexanecarboxamide[no description available]low00N-acyl-amino acid
1-[1-[oxo(1-pyrrolidinyl)methyl]cyclohexyl]-3-(phenylmethyl)urea[no description available]low00N-acyl-amino acid
2-[[[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methyl-3-furanyl]-oxomethyl]amino]acetic acid ethyl ester[no description available]low00N-acyl-amino acid
1-(3-fluorophenyl)-3-[1-[(4-methyl-1-piperazinyl)-oxomethyl]cyclohexyl]urea[no description available]low00N-acyl-amino acid
1-[1-[(4-hydroxy-1-piperidinyl)-oxomethyl]cyclohexyl]-3-(2-methoxyphenyl)urea[no description available]low00N-acyl-amino acid
1-[1-[3,4,6,7,8,8a-hexahydro-1H-pyrrolo[1,2-a]pyrazin-2-yl(oxo)methyl]cyclohexyl]-3-cyclohexylurea[no description available]low00N-acyl-amino acid
2-acetamido-3,3,3-trifluoro-2-[(6-methylsulfonyl-1,3-benzothiazol-2-yl)amino]propanoic acid methyl ester[no description available]low00N-acyl-amino acid
N-[2-(4-fluoroanilino)-2-oxoethyl]-2-furancarboxamide[no description available]low00N-acyl-amino acid
N-[2-(2,3-dimethylanilino)-2-oxoethyl]-3-(3-methylphenoxy)propanamide[no description available]low00N-acyl-amino acid
Methyl(2-furoylamino)acetic acid[no description available]low00N-acyl-amino acid
N-[3-(4-chlorophenyl)-5-oxo-4-pyrazolidinyl]-3-methylbenzamide[no description available]low00N-acyl-amino acid
N-[4-cyano-5-methyl-2-oxo-3-(trifluoromethyl)-1H-pyrrol-3-yl]cyclopropanecarboxamide[no description available]low00N-acyl-amino acid
2,4-dichloro-N-[2,4,6-trioxo-1-(phenylmethyl)-5-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzamide[no description available]low00N-acyl-amino acid
N-[1-oxo-1-[[4-(2-pyridinyl)-2-thiazolyl]amino]propan-2-yl]-2-furancarboxamide[no description available]low00N-acyl-amino acid
2-(1-oxopropylamino)acetic acid phenacyl ester[no description available]low00N-acyl-amino acid
N-[2-(3-ethoxypropylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-2-pyrazinecarboxamide[no description available]low00N-acyl-amino acid
2-(2-methoxyphenyl)-1-oxo-N-[2-oxo-2-[4-(2-pyridinyl)-1-piperazinyl]ethyl]-4-isoquinolinecarboxamide[no description available]low00N-acyl-amino acid
N-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-2-[[1-oxo-2-(1-oxo-2-isoquinolinyl)ethyl]amino]acetamide[no description available]low00N-acyl-amino acid
2-[[2-(3-methyl-1-oxo-2-isoquinolinyl)-1-oxoethyl]amino]acetic acid ethyl ester[no description available]low00N-acyl-amino acid
l 735821[no description available]low00N-acyl-amino acid
sr 142948[no description available]low00N-acyl-amino acid
indolylacryloylglycine[no description available]low00N-acyl-amino acid
glycine linoleamide[no description available]low00N-acyl-amino acid
bengamide e[no description available]low00N-acyl-amino acid
rhc 3659[no description available]low00N-acyl-amino acid
N-[2-[2-(dibutylamino)ethylamino]-2-oxoethyl]-2-thiophenecarboxamide[no description available]low00N-acyl-amino acid
n-hexanoyl-l-homoserine lactone[no description available]low00N-acyl-amino acid
n-dodecanoyl-dl-homoserine lactone[no description available]low00N-acyl-amino acid
spergualin[no description available]low00N-acyl-amino acid
3-methylbutanoic acid [(2R,3S,6S,7R)-3-[[(3-formamido-2-hydroxyphenyl)-oxomethyl]amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl] ester[no description available]low00N-acyl-amino acid
N-[5-Ethyl-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride[no description available]low00N-acyl-amino acidanticoronaviral agent
N-[5-Bromo-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride[no description available]low00N-acyl-amino acidanticoronaviral agent
N-[5-Fluoro-1-(2-morpholin-4-ylethyl)-2-oxo-3H-indol-3-yl]acetamide;hydron;chloride[no description available]low00N-acyl-amino acidanticoronaviral agent
2-[[[4-[[5-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentylamino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]acetic acid tert-butyl ester[no description available]low00N-acyl-amino acid;
tert-butyl ester
3-(2,4-dimethoxyphenyl)-N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]-2-oxoethyl]-4-oxo-1-phthalazinecarboxamide[no description available]low00N-acyl-amino acid
folic acid[no description available]low00folic acids;
N-acyl-amino acid		human metabolite;
mouse metabolite;
nutrient
raltitrexed[no description available]low00N-acyl-amino acid
ConditionIndicatedRelationship StrengthStudiesTrials
Bacterial Disease0low10
Bacterial Infection0low10
Bacterial Infections0low10
Cancer of Skin0low10
Cancer of the Skin0low10
Dehydration0low20
Diathesis0low10
Disease Resistance0low60
Disease Susceptibility0low10
Electrolytes0low20
Infection, Bacterial0low10
Infections, Bacterial0low10
Infections, Pseudomonas0low10
Malignant Melanoma0low10
Melanoma0low10
Neoplasms, Skin0low10
Pseudomonas aeruginosa Infection0low10
Pseudomonas Infections0low10
Resistance, Disease0low60
Skin Cancer0low10
Skin Neoplasms0low10
Susceptibility, Disease0low10
Water Stress0low20