Page last updated: 2024-08-05 15:43:51

VEGF activator

Any activator of vascular endothelial growth factor (VEGF).

ChEBI ID: 91189

Members (2)

MemberDefinitionClass
GS4012A hydrochloride obtained by combining the free base of GS4012 with one molar equivalent of hydrochloric acid.GS4012
GS4012 free baseA member of the class of pyridines that is 2-(pyridin-4-yl)ethane-1-thiol in which the thiol hydrogen is replaced by a 4-methoxyphenyl group.GS4012 free base

Research

Studies (10)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's7 (70.00)24.3611
2020's2 (20.00)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%

Protein Targets (7)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
aldehyde dehydrogenase 1 family, member A1Homo sapiens (human)Potency39.810711
bromodomain adjacent to zinc finger domain 2BHomo sapiens (human)Potency44.668411
Chain A, 2-oxoglutarate OxygenaseHomo sapiens (human)Potency25.118911
Chain A, Putative fructose-1,6-bisphosphate aldolaseGiardia intestinalisPotency15.811411
chromobox protein homolog 1Homo sapiens (human)Potency100.000011
euchromatic histone-lysine N-methyltransferase 2Homo sapiens (human)Potency25.118911
Rap guanine nucleotide exchange factor 3Homo sapiens (human)Potency44.668411