| Assay ID | Title | Year | Journal | Article |
|---|
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID239799 | Binding affinity for alpha 1a adrenoceptor | 2005 | Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
| Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses. |
| AID239800 | Binding affinity for alpha 1b adrenoceptor | 2005 | Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
| Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses. |
| AID239801 | Binding affinity for alpha 1d adrenoceptor | 2005 | Journal of medicinal chemistry, Jul-28, Volume: 48, Issue:15
| Range and sensitivity as descriptors of molecular property spaces in dynamic QSAR analyses. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
| AID1781485 | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781471 | Induction of mitotic arrest in HRPE Cells overexpressing MYC assessed as polyploidy at 5 uM by acridine orange staining based fluorescence microscopic analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781484 | Cytotoxicity against human HeLa cells assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID729718 | Inhibition of [3H]SCH23390 binding to dopamine D1 receptor (unknown origin) expressed in human HEK293 cells at 10 uM by liquid scintillation counter relative to control | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1781478 | Cytotoxicity against human wild type p53HCT116 cells assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781489 | Induction of cell cycle arrest in human RPE cells expressing MYC-Bcl2 assessed as foci in colocalized Aurora kinase A at 4 uM for 6 hrs by immunostaining analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID729713 | Displacement of [3H]spiperone from dopamine D2 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counter | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1781482 | Cytotoxicity against HRPE cells overexpressing MYC/Bcl2 assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781477 | Cytotoxicity against human NCI-H460 cells assessed as centrosome amplification and declustering by measuring multiple foci by immunostaining analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781472 | Induction of mitotic arrest in HRPE Cells overexpressing MYC measured for 24 hrs by acridine orange staining based fluorescence microscopic analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781469 | Induction of mitotic arrest in HRPE Cells overexpressing MYC-Bcl2 measured for 46 to 62 hrs by time-lapse analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID729715 | Inhibition of [3H]Ketanserin binding to 5-HT2A receptor (unknown origin) expressed in HEK293 cells at 10 uM by liquid scintillation counter relative to control | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1890610 | Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay | 2022 | Bioorganic & medicinal chemistry, 04-15, Volume: 60 | Isolation, synthesis and bioactivity evaluation of isoquinoline alkaloids from Corydalis hendersonii Hemsl. against gastric cancer in vitro and in vivo. |
| AID729714 | Displacement of [3H]SCH23390 from dopamine D1 receptor (unknown origin) expressed in human HEK293 cells by liquid scintillation counter | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1781476 | Inhibition of AURKB (unknown origin) in HRPE cells overexpressing MYC/Bcl2 assessed as decrease in H3PS10 fluorescence intensity at 20 uM measured for 6 hrs by immunostaining based fluorescence microscopic analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781479 | Cytotoxicity against human HCT116-p53-null cells assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781473 | Induction of mitotic arrest in HRPE Cells overexpressing MYC assessed as polyploidy measured for 48 hrs by acridine orange staining based fluorescence microscopic analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781487 | Cytotoxicity against HRPE cells overexpressing MYC-H2BGFP assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID729712 | Displacement of [3H]8-OH-DPAT from 5-HT1A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counter | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1781481 | Cytotoxicity against HRPE cells overexpressing MYC assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781486 | Cytotoxicity against human SW480 cells assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID729717 | Inhibition of [3H]spiperone binding to dopamine D2 receptor (unknown origin) expressed in human HEK293 cells at 10 uM by liquid scintillation counter relative to control | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID729711 | Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) expressed in HEK293 cells by liquid scintillation counter | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1890609 | Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay | 2022 | Bioorganic & medicinal chemistry, 04-15, Volume: 60 | Isolation, synthesis and bioactivity evaluation of isoquinoline alkaloids from Corydalis hendersonii Hemsl. against gastric cancer in vitro and in vivo. |
| AID1781483 | Cytotoxicity against human A549 cells assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781474 | Induction of cell cycle arrest in HRPE cells overexpressing MYC/Bcl2 assessed as centrosome amplification measured after 6 hrs by DAPI staining based analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1890611 | Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay | 2022 | Bioorganic & medicinal chemistry, 04-15, Volume: 60 | Isolation, synthesis and bioactivity evaluation of isoquinoline alkaloids from Corydalis hendersonii Hemsl. against gastric cancer in vitro and in vivo. |
| AID1781480 | Cytotoxicity against human NCI-H23 cells harboring MYC assessed as cell viability measured after 72 hrs by MTT assay | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781490 | Induction of cell cycle arrest in human RPE cells expressing MYC-Bcl2 assessed as disorganized alpha-tubulin at 4 uM for 6 hrs by immunostaining analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781491 | Induction of cell cycle arrest in human RPE cells expressing MYC-Bcl2 assessed as disorganized NUMA1 at 4 uM for 6 hrs by immunostaining analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781470 | Induction of mitotic arrest in HRPE Cells overexpressing MYC at 20 uM by acridine orange staining based fluorescence microscopic analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID729716 | Inhibition of [3H]8-OH-DPAT binding to 5-HT1A receptor (unknown origin) expressed in HEK293 cells at 10 uM by liquid scintillation counter relative to control | 2013 | Bioorganic & medicinal chemistry, Feb-15, Volume: 21, Issue:4
| Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D(1), D(2) and serotonin 5-HT(1A) multi-action profile. |
| AID1781475 | Inhibition of AURKA (unknown origin) in HRPE cells overexpressing MYC/Bcl2 assessed as inhibition of autophosphorylation of threonine 288 at 20 uM measured for 6 hrs by immunostaining based fluorescence microscopic analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1781488 | Induction of cell cycle arrest in human RPE cells expressing MYC-Bcl2 assessed as foci in colocalized gamma-tubulin at 4 uM for 6 hrs by immunostaining analysis | 2021 | Journal of natural products, 08-27, Volume: 84, Issue:8
| The Phytochemical Scoulerine Inhibits Aurora Kinase Activity to Induce Mitotic and Cytokinetic Defects. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |