acutumine: dechloroacutumine is the dechloro derivative of acutumine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10200848 |
| CHEMBL ID | 391628 |
| CHEBI ID | 80789 |
| SCHEMBL ID | 2240436 |
| MeSH ID | M0408855 |
| Synonym |
|---|
| acutumine |
| CHEMBL391628 |
| chebi:80789 , |
| 17088-50-5 |
| C16910 |
| SCHEMBL2240436 |
| Q27149835 |
| (1s,4's,6s,10r,11s)-11-chloro-4'-hydroxy-3',4,5-trimethoxy-7-methylspiro[7-azatricyclo[4.3.3.01,6]dodec-4-ene-10,5'-cyclopent-2-ene]-1',3-dione |
| HY-N9737 |
| CS-0203723 |
| (?)-acutumine |
| AKOS040763135 |
| Class | Description |
|---|---|
| alkaloid | Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID301050 | Cytotoxicity against human Hep G2.2.15 cells | 2007 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 17, Issue:19 | Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida. |
| AID301051 | Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of surface antigen HBsAg secretion | 2007 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 17, Issue:19 | Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida. |
| AID301052 | Antiviral activity against HBV transfected Hep G2.2.15 cells assessed as inhibition of e antigen HBsAg secretion | 2007 | Bioorganic & medicinal chemistry letters, Oct-01, Volume: 17, Issue:19 | Two new alkaloids and active anti-hepatitis B virus constituents from Hypserpa nitida. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (24.80) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 18 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||