Target type: molecularfunction
Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. [EC:3.1.1.23, MetaCyc:3.1.1.23-RXN]
Acylglycerol lipase activity refers to the enzymatic hydrolysis of ester bonds in acylglycerols, which are lipids composed of glycerol and fatty acids. This process is critical for the digestion and mobilization of fats in living organisms. Lipases, the enzymes responsible for this activity, catalyze the breakdown of acylglycerols into glycerol and free fatty acids. This breakdown occurs through the addition of a water molecule to the ester bond, cleaving it and releasing the fatty acid. The specific position of the ester bond that is cleaved depends on the type of lipase. For example, some lipases are specific for the hydrolysis of the ester bond at the sn-1 or sn-3 position of the glycerol backbone, while others can hydrolyze all three ester bonds. The hydrolysis of acylglycerols by lipases is essential for the digestion of dietary fats in the small intestine. Lipases secreted by the pancreas, such as pancreatic lipase, play a crucial role in breaking down triglycerides, the most common type of acylglycerol, into glycerol and fatty acids. These free fatty acids can then be absorbed by the intestinal cells and transported to various tissues for energy production or storage. Acylglycerol lipase activity is also important in the mobilization of stored fat in adipose tissue. When energy reserves are low, lipases in adipose tissue, such as hormone-sensitive lipase, hydrolyze stored triglycerides, releasing free fatty acids into the bloodstream. These fatty acids can then be used as an energy source by other tissues. In addition to their roles in digestion and energy metabolism, lipases are involved in various cellular processes, including lipid signaling, membrane remodeling, and the synthesis of specialized lipid molecules. Their activity is tightly regulated by various factors, including hormones, dietary intake, and cellular signaling pathways, ensuring proper lipid metabolism and homeostasis.'
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| Protein | Definition | Taxonomy |
|---|---|---|
| Diacylglycerol lipase-alpha | A diacylglycerol lipase-alpha that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9Y4D2] | Homo sapiens (human) |
| Monoacylglycerol lipase ABHD6 | A monoacylglycerol lipase ABHD6 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9BV23] | Homo sapiens (human) |
| Monoglyceride lipase | A monoglyceride lipase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q99685] | Homo sapiens (human) |
| Monoglyceride lipase | A monoglyceride lipase that is encoded in the genome of rat. [OMA:Q8R431, PRO:DNx] | Rattus norvegicus (Norway rat) |
| Diacylglycerol lipase-beta | A diacylglycerol lipase-beta that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8NCG7] | Homo sapiens (human) |
| Lysophosphatidylserine lipase ABHD12 | A lysophosphatidylserine lipase ABHD12 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8N2K0] | Homo sapiens (human) |
| Diacylglycerol lipase-alpha | A diacylglycerol lipase-alpha that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9Y4D2] | Homo sapiens (human) |
| Monoacylglycerol lipase ABHD6 | A monoacylglycerol lipase ABHD6 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q9BV23] | Homo sapiens (human) |
| Monoglyceride lipase | A monoglyceride lipase that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q99685] | Homo sapiens (human) |
| Diacylglycerol lipase-beta | A diacylglycerol lipase-beta that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8NCG7] | Homo sapiens (human) |
| Lysophosphatidylserine lipase ABHD12 | A lysophosphatidylserine lipase ABHD12 that is encoded in the genome of human. [PRO:DNx, UniProtKB:Q8N2K0] | Homo sapiens (human) |
| Phosphatidylserine lipase ABHD16A | A phosphatidylserine lipase ABHD16A that is encoded in the genome of human. [PRO:DNx, UniProtKB:O95870] | Homo sapiens (human) |
| Fatty-acid amide hydrolase 1 | A fatty-acid amide hydrolase 1 that is encoded in the genome of human. [PRO:DNx, UniProtKB:O00519] | Homo sapiens (human) |
| Compound | Definition | Classes | Roles |
|---|---|---|---|
| ro 48-8071 | Ro 48-8071 : An aromatic ketone that is 2-fluoro-4'-bromobenzophenone in which the hydrogen at position 4 (meta to the fluoro group) is replaced by a 6-[methyl(prop-2-en-1-yl)amino]hexyl}oxy group. An inhibitor of lanosterol synthase. Ro 48-8071: a cholesterol synthesis inhibitor; structure in first source | aromatic ether; aromatic ketone; bromobenzenes; monofluorobenzenes; olefinic compound; tertiary amino compound | antineoplastic agent; EC 5.4.99.7 (lanosterol synthase) inhibitor |
| benzo(b)thiophene-2-boronic acid | benzo(b)thiophene-2-boronic acid: inhibits AmpC beta-lactamase; structure in first source | ||
| cannabinol | Cannabinol: A physiologically inactive constituent of Cannabis sativa L. | dibenzopyran | |
| disulfiram | organic disulfide; organosulfur acaricide | angiogenesis inhibitor; antineoplastic agent; apoptosis inducer; EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor; EC 3.1.1.1 (carboxylesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; EC 5.99.1.2 (DNA topoisomerase) inhibitor; ferroptosis inducer; fungicide; NF-kappaB inhibitor | |
| ethylmaleimide | Ethylmaleimide: A sulfhydryl reagent that is widely used in experimental biochemical studies. | maleimides | anticoronaviral agent; EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor; EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor; EC 2.7.1.1 (hexokinase) inhibitor |
| phenylmethylsulfonyl fluoride | phenylmethanesulfonyl fluoride : An acyl fluoride with phenylmethanesulfonyl as the acyl group. Phenylmethylsulfonyl Fluoride: An enzyme inhibitor that inactivates IRC-50 arvin, subtilisin, and the fatty acid synthetase complex. | acyl fluoride | serine proteinase inhibitor |
| propofol | propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group. Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS. | phenols | anticonvulsant; antiemetic; intravenous anaesthetic; radical scavenger; sedative |
| 1,6-bis(cyclohexyloximinocarbonyl)hexane | 1,6-bis(cyclohexyloximinocarbonyl)hexane: selective inhibitor of canine platelet diglyceride lipase | carbamate ester; organonitrogen compound | |
| thiram | thiram : An organic disulfide that results from the formal oxidative dimerisation of N,N-dimethyldithiocarbamic acid. It is widely used as a fungicidal seed treatment. Thiram: A dithiocarbamate chemical, used commercially in the rubber processing industry and as a fungicide. In vivo studies indicate that it inactivates the enzyme GLUTATHIONE REDUCTASE. It has mutagenic activity and may induce chromosomal aberrations. | organic disulfide | antibacterial drug; antifungal agrochemical; antiseptic drug |
| carbaryl | carbaryl : A carbamate ester obtained by the formal condensation of 1-naphthol with methylcarbamic acid. Carbaryl: A carbamate insecticide and parasiticide. It is a potent anticholinesterase agent belonging to the carbamate group of reversible cholinesterase inhibitors. It has a particularly low toxicity from dermal absorption and is used for control of head lice in some countries. | carbamate ester; naphthalenes | acaricide; agrochemical; carbamate insecticide; EC 3.1.1.7 (acetylcholinesterase) inhibitor; EC 3.1.1.8 (cholinesterase) inhibitor; plant growth retardant |
| bis(1-piperidylthiocarbonyl)disulfide | bis(1-piperidylthiocarbonyl)disulfide: indicator for analysis of copper; structure | ||
| tetramethylthiuram monosulfide | |||
| 4,4'-dithiodimorpholine | 4,4'-dithiodimorpholine: rubber vulcanizing agent causing occupational dermatitis; structure | ||
| benzil | benzil : An alpha-diketone that is ethane-1,2-dione substituted by phenyl groups at positions 1 and 2 respectively. benzil: structure | alpha-diketone; aromatic ketone | |
| phenyl trifluoromethyl ketone | phenyl trifluoromethyl ketone: converted to trifluoroacetic acid in water | ||
| hydratropic acid | hydratropic acid : A 2-arylpropionic acid carrying a phenyl group at position 2. It is a metabolite of alpha-methylstyrene (AMS), a volatile hydrocarbon. hydratropic acid: RN given refers to cpd without isomeric designation; structure | 2-arylpropionic acid | human xenobiotic metabolite |
| methyl diethyldithiocarbamate | |||
| diphenyl disulfide | benzenes | ||
| n-phenylmaleimide | N-phenylmaleimide: structure in Merck Index, 9th ed, #7104 | ||
| dronabinol | Delta(9)-tetrahydrocannabinol : A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. The principal psychoactive constituent of the cannabis plant, it is used for treatment of anorexia associated with AIDS as well as nausea and vomiting associated with cancer chemotherapy. Dronabinol: A psychoactive compound extracted from the resin of Cannabis sativa (marihuana, hashish). The isomer delta-9-tetrahydrocannabinol (THC) is considered the most active form, producing characteristic mood and perceptual changes associated with this compound. | benzochromene; diterpenoid; phytocannabinoid; polyketide | cannabinoid receptor agonist; epitope; hallucinogen; metabolite; non-narcotic analgesic |
| 1,2-benzisothiazoline-3-one | 1,2-benzisothiazoline-3-one: a preservative in water-based solutions such as paints, cutting fluids, printing inks, cleaning agents, polyvinyl chloride gloves, etc. benzo[d]isothiazol-3-one : An organic heterobicyclic compound based on a fused 1,2-thiazole and benzene bicyclic ring skeleton, with the S atom positioned adjacent to one of the positions of ring fusion. | organic heterobicyclic compound; organonitrogen heterocyclic compound | disinfectant; drug allergen; environmental contaminant; platelet aggregation inhibitor; sensitiser; xenobiotic |
| 1,6-bismaleimidohexane | |||
| phenmedipham | phenmedipham : A carbamate ester that is (3-methylphenyl)carbamic acid in which the hydrogen of the hydroxy group has been replaced by a 3-[(methoxycarbonyl)amino]phenyl group. phenmedipham: minor descriptor (72-84); on-line search CARBAMATES (72-84); Index Medicus search HERBICIDES, CARBAMATE (75-84), CARBAMATES (72-75) | carbamate ester | environmental contaminant; herbicide; xenobiotic |
| diacerein | diacerein: chelates with bivalent metals; a quinone which possesses redox properties; metabolized to active rhein; proposed mechanisms include inhibiting IL1 and metalloproteinases; called a slow acting symptomatic drug in osteoarthritis; no effect of cyclooxygenase; | anthraquinone | |
| cannabichromene | 1-benzopyran | ||
| 2-n-octyl-4-isothiazolin-3-one | octhilinone : A member of the class of 1,2-thiazole that is 1,2-thiazol-3-one substituted on the nitrogen (position 2) by an octyl group. A fungicide and antibacterial agent, it is used for treatment of canker and other fungal and bacterial diseases in fruit trees. It is no longer approved for use within the European Union. | 1,2-thiazoles | antibacterial agent; antifungal agrochemical; environmental contaminant; xenobiotic |
| phenylethane boronic acid | |||
| n-methylmaleimide | N-methylmaleimide: structure in first source | ||
| amperozide | amperozide : A member of the class of ureas that is urea in which three of the four hydrogens are replaced by ethyl and 4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl groups. An atypical antipsychotic which was in clinical development for the treatment of schizophrenia and substance-related disorders. It is a potent 5-HT2A antagonist and used in veterinary medicine because of its sedative effect on pigs. | diarylmethane; monofluorobenzenes; N-alkylpiperazine; secondary carboxamide; ureas | anxiolytic drug; dopamine uptake inhibitor; geroprotector; second generation antipsychotic; serotonergic antagonist |
| n-benzylmaleimide | |||
| n,n'-4-phenylenedimaleimide | |||
| (6ar-trans)-isomer of tetrahydrocannabivarin 9 | |||
| n-(2-methoxyphenyl)maleimide | N-(2-methoxyphenyl)maleimide: structure given in first source | ||
| delta(9)-tetrahydrocannabinolic acid | Delta(9)-tetrahydrocannabinolic acid : A diterpenoid that is 6a,7,8,10a-tetrahydro-6H-benzo[c]chromene substituted at position 1 by a hydroxy group, positions 6, 6 and 9 by methyl groups and at position 3 by a pentyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant. | benzochromene; diterpenoid; hydroxy monocarboxylic acid; phytocannabinoid; polyketide | anti-inflammatory agent; biomarker; metabolite; neuroprotective agent |
| n-(4-bromophenyl)maleimide | N-(4-bromophenyl)maleimide: structure given in first source | ||
| 3-octylthio-1,1,1-trifluoro-2-propanone | 3-octylthio-1,1,1-trifluoro-2-propanone: a pesticide synergist; inhibits juvenile hormone esterase | ||
| 1,1'-biphenyl-4-yl-boronic acid | |||
| celastrol methyl ester | celastrol methyl ester: isolated from Tripterygium wilfordii; potent inhibitory activity on both Kir2.1 and ERG1 potassium channels, leading to LONG QT SYNDROME | carboxylic ester | |
| cannabidiolic acid | cannabidiolic acid : A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a 3-p-mentha-1,8-dien-3-yl (limonene) group. cannabidiolic acid: structure | dihydroxybenzoic acid; phytocannabinoid; polyketide; resorcinols | |
| 4-methoxyphenylboronic acid | 4-methoxyphenylboronic acid: structure in first source | ||
| euphol | euphol: from Euphorbia acaulis Roxb.; structure given in first source | triterpenoid | |
| arachidonic acid | arachidonate : A long-chain fatty acid anion resulting from the removal of a proton from the carboxy group of arachidonic acid. icosa-5,8,11,14-tetraenoic acid : Any icosatetraenoic acid with the double bonds at positions 5, 8, 11 and 14. | icosa-5,8,11,14-tetraenoic acid; long-chain fatty acid; omega-6 fatty acid | Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; human metabolite; mouse metabolite |
| oleic acid | oleic acid : An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry. Oleic Acid: An unsaturated fatty acid that is the most widely distributed and abundant fatty acid in nature. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. (Stedman, 26th ed) | octadec-9-enoic acid | antioxidant; Daphnia galeata metabolite; EC 3.1.1.1 (carboxylesterase) inhibitor; Escherichia coli metabolite; mouse metabolite; plant metabolite; solvent |
| cannabidiol | cannabidiol : An cannabinoid that is cyclohexene which is substituted by a methyl group at position 1, a 2,6-dihydroxy-4-pentylphenyl group at position 3, and a prop-1-en-2-yl group at position 4. Cannabidiol: Compound isolated from Cannabis sativa extract. | olefinic compound; phytocannabinoid; resorcinols | antimicrobial agent; plant metabolite |
| urb 597 | cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester: a fatty acid amide hydrolase inhibitor; structure in first source | biphenyls | |
| jnj-1661010 | N-arylpiperazine | ||
| orlistat | orlistat : A carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug. Orlistat: A lactone derivative of LEUCINE that acts as a pancreatic lipase inhibitor to limit the absorption of dietary fat; it is used in the management of obesity. | beta-lactone; carboxylic ester; formamides; L-leucine derivative | anti-obesity agent; bacterial metabolite; EC 2.3.1.85 (fatty acid synthase) inhibitor; EC 3.1.1.3 (triacylglycerol lipase) inhibitor |
| 2-octyl-gamma-bromoacetoacetate | 2-octyl-gamma-bromoacetoacetate: RN given refers to (D)-isomer; structure | ||
| arachidonyltrifluoromethane | AACOCF3 : A fatty acid derivative that is arachidonic acid in which the OH part of the carboxy group has been replaced by a trifluoromethyl group arachidonyltrifluoromethane: structure given in first source; inhibits 85-kDa phospholipase A2 | fatty acid derivative; ketone; olefinic compound; organofluorine compound | EC 3.1.1.4 (phospholipase A2) inhibitor |
| anandamide | anandamide : An N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. | endocannabinoid; N-acylethanolamine 20:4 | human blood serum metabolite; neurotransmitter; vasodilator agent |
| glyceryl 2-arachidonate | 2-arachidonoylglycerol : An endocannabinoid and an endogenous agonist of the cannabinoid receptors (CB1 and CB2). It is an ester formed from omega-6-arachidonic acid and glycerol. glyceryl 2-arachidonate: binds to cannabinoid receptors; structure in first source | 2-acylglycerol 20:4; endocannabinoid | human metabolite |
| oleylamide | aliphatic amide : A carboxamide in which the amide linkage is bonded directly to an aliphatic system. oleamide : A fatty amide derived from oleic acid. oleylamide: plastic additive; can cause contact urticaria; RN given refers to (Z)-isomer; a sleep inducing factor | primary fatty amide | human metabolite; plant metabolite |
| n-arachidonylglycine | N-arachidonoylglycine : Biologically active derivative of anandamide N-arachidonylglycine: structure in first source | fatty amide; N-acylglycine | |
| N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine | N-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoylethanolamine : An N-acylethanolamine 22:6 that is the ethanolamide of (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoic acid. synaptamide: structurally similar to the endocannabinoid N-arachidonoylethanolamine (anandamide) | endocannabinoid; N-acylethanolamine 22:6 | |
| [2-(1-piperidinyl)-1,3-benzothiazol-6-yl]-[4-(2-pyridinyl)-1-piperazinyl]methanone | piperazines; pyridines | ||
| arachidonyl-2-chloroethylamide | arachidonyl-2-chloroethylamide: a potent and selective agonist of the neuronal cannabinoid receptor; structure in first source arachidonyl-2'-chloroethylamide : A fatty amide obtained by the formal condensation of arachidonic acid with 2-chloroethanamine. It is a potent agonist of the CB1 receptor (Ki = 1.4 nM) and also has a low affinity for the CB2 receptor (Ki = 3100 nM). | fatty amide; organochlorine compound; secondary carboxamide; synthetic cannabinoid | CB1 receptor agonist; CB2 receptor agonist; neuroprotective agent |
| cannabigerol | cannabigerol : A member of the class of resorcinols that is resorcinol which is substituted by a (2E)-3,7-dimethylocta-2,6-dien-1-yl group at position 2 and by a pentyl group at position 5. It is a natural product found in Cannabis sativa and Helichrysum species. cannabigerol: RN given refers to (E)-isomer; structure given in first source | phytocannabinoid; resorcinols | anti-inflammatory agent; antibacterial agent; antioxidant; appetite enhancer; cannabinoid receptor agonist; neuroprotective agent; plant metabolite |
| 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2h-pyran-2-one | 6-(bromomethylene)tetrahydro-3-(1-naphthaleneyl)-2H-pyran-2-one: structure given in first source; potent irreversible, mechanism-based inhibitor of myocardial calcium-independent phospholipase A2 | naphthalenes | |
| guineensine | guineensine: an Acyl-CoA: cholesterol acyltransferase inhibitor, from the fruits of Piper longum; structure in first sourc | benzodioxoles | |
| cannabigerolic acid | cannabigerolic acid : A dihydroxybenzoic acid that is olivetolic acid in which the hydrogen at position 3 is substituted by a geranyl group. A biosynthetic precursor to Delta(9)-tetrahydrocannabinol, the principal psychoactive constituent of the cannabis plant. cannabigerolic acid: structure in first source | dihydroxybenzoic acid; diterpenoid; phytocannabinoid; polyketide; resorcinols | |
| omdm-2 cpd | OMDM-2 cpd: structure in first source | ||
| cay 10499 | carbamate ester | ||
| CAY10435 | oxazolopyridine | ||
| arachidonoylserotonin | arachidonoylserotonin: an NSAID with antinociceptive activity; fatty acid amide hydrolase inhibitor; structure in first source N-arachidonoylserotonin : An N-acylserotonin obtained by formal condensation of the carboxy group of arachidonic acid with the primary amino group of serotonin. | N-acylserotonin; phenols | anti-inflammatory agent; anticonvulsant; antioxidant; capsaicin receptor antagonist; EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; human metabolite; signalling molecule |
| urb 524 | |||
| ol-135 | |||
| methyl arachidonylfluorophosphonate | phosphonic ester | ||
| urb602 | URB602: inhibitor of 2-arachidonoylglycerol (2-AG)-deactivating enzyme, monoacylglycerol lipase, structure in first source | ||
| n-benzylhexadecanamide | N-benzylhexadecanamide : A macamide resulting from the formal condensation of the carboxy group of hexadecanoic acid with benzylamine. A moderate inhibitor of fatty acid amide hydrolase. N-benzylhexadecanamide: isolated from Lepidium meyenii; structure in first source | macamide; secondary carboxamide | EC 3.5.1.99 (fatty acid amide hydrolase) inhibitor; neuroprotective agent; plant metabolite |
| ly2183240 | LY2183240: structure in first source | biphenyls | |
| methylphenidate | N-phenyl-4-(quinolin-2-ylmethyl)piperazine-1-carboxamide: a fatty acid amide hydrolase inhibitor; structure in first source | ||
| 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea | 1-(4-chlorophenyl)-3-(3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl)urea: structure in first source | ||
| cannabidivarin | cannabidivarin: from Cannabis sativa | monoterpenoid | |
| omdm 169 | OMDM 169: has antinociceptive activity; structure in first source | ||
| 4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid | |||
| t-tucb | |||
| pf 04457845 | |||
| am 6701 | |||
| jzl 184 | JZL 184: inhibits monoacylglycerol lipase; structure in first source | benzodioxoles | |
| pf 3845 | PF 3845: inhibits fatty acid amide hydrolase | piperidines | |
| pf 750 | N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carboxamide: a fatty acid amide hydrolase inhibitor; structure in first source | quinolines | |
| azd7687 | AZD7687: structure in first source | ||
| palmostatin b | palmostatin B: inhibits acyl protein thioesterase 1; structure in first source | ||
| jzl195 | JZL195: inhibits both ​fatty-acid amide hydrolase 1 and ​monoglyceride lipase; structure in first source | ||
| sar127303 | SAR127303: inhibits monoacylglycerol lipase; structure in first source | ||
| mjn110 | MJN110: structure in first source |