Assay ID | Title | Year | Journal | Article |
AID596528 | Antifungal activity against Trichophyton rubrum C 113 2000 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596527 | Antifungal activity against Microsporum gypseum C 115 2000 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID1199848 | Fluorescence quenching assessed as fluorescence signal reduction at 10 uM after 10 mins | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID596444 | Antifungal activity against Candida tropicalis C 131 2000 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596439 | Cytotoxicity against human MCF7 cells assessed as cell growth after 2 days by sulforhodamine B assay | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID1199845 | Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenzyme A production after 45 mins by CoA-based HTS counter screen assay | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID596525 | Antifungal activity against Aspergillus flavus ATCC 9170 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596443 | Antifungal activity against Candida albicans ATCC 10213 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596526 | Antifungal activity against Aspergillus niger ATCC 9029 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596445 | Antifungal activity against Saccharomyces cerevisiae ATCC 9763 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID1199849 | Fluorescence quenching in HTS buffer assessed as fluorescence signal reduction at 10 uM after 10 mins | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID1199850 | Fluorescence quenching in HTS buffer with 7.5 uM CoA assessed as fluorescence signal reduction at 10 uM after 10 mins | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID1199847 | Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 assessed as H3K27 acetylated product at 125 uM after 45 mins by Slot bolt inhibiton assay | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID596447 | Antifungal activity against Aspergillus fumigatus ATCC 26934 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID439745 | Displacement of [3H]ethanolamine from human recombinant FAAH by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. |
AID596529 | Antifungal activity against Trichophyton mentagrophytes ATCC 9972 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596446 | Antifungal activity against Cryptococcus neoformans ATCC 32264 | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID439743 | Selectivity ratio of IC50 for human FAAH to IC50 for human MGL | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. |
AID1199844 | Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenzyme A production after 45 mins by CPM based HTS assay | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID1199862 | Fluorescence quenching in HTS buffer with 20 uM 7-diethylamino-3-(4'-maleimidyl-phenyl)-4-methylcoumarin assessed as fluorescence signal reduction at 10 uM after 10 mins | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
AID596440 | Cytotoxicity against human H460 cells assessed as cell growth after 2 days by sulforhodamine B assay | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID439744 | Displacement of [3H]2-OG from human MGL by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Dec-10, Volume: 52, Issue:23
| Synthesis and in vitro evaluation of N-substituted maleimide derivatives as selective monoglyceride lipase inhibitors. |
AID596441 | Cytotoxicity against human SF268 cells assessed as cell growth after 2 days by sulforhodamine B assay | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID596442 | Cytotoxicity against human erythrocytes assessed as hemolysis by spectrometric analysis | 2011 | Bioorganic & medicinal chemistry, May-01, Volume: 19, Issue:9
| Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. |
AID1199846 | Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 assessed as H3K56 acetylated product at 125 uM after 45 mins by Slot bolt inhibiton assay | 2015 | Journal of medicinal chemistry, Mar-12, Volume: 58, Issue:5
| PAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |