Compounds > tetraphenylcyclopentadienone
Page last updated: 2024-09-23

tetraphenylcyclopentadienone

Description

tetraphenylcyclopentadienone: singlet oxygen trapping agent [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID68068
CHEMBL ID4534655
CHEBI ID188913
SCHEMBL ID516326
MeSH IDM0054146

Synonyms (59)

Synonym
tetraphenylcyclopentadienone
tetracyclone
2, 2,3,4,5-tetraphenyl-
2,4,5-tetraphenylcyclopentadienone
tetraphenyl-2,4-cyclopentadien-1-one
479-33-4
tetracyclon
cyclone (compound)
nsc-2060
cyclone
nsc2060
2,4,5-tetraphenyl-2,4-cyclopentadienone
nsc243761
nsc220314
nsc-220314
nsc-243761
2,3,4,5-tetraphenylcyclopenta-2,4-dien-1-one
inchi=1/c29h20o/c30-29-27(23-17-9-3-10-18-23)25(21-13-5-1-6-14-21)26(22-15-7-2-8-16-22)28(29)24-19-11-4-12-20-24/h1-20
2,4-cyclopentadien-1-one, 2,3,4,5-tetraphenyl-
STK363114
GHL.PD_MITSCHER_LEG0.162
tetraphenylcyclopentadienone, 98%
OPREA1_165374
2,3,4,5-tetraphenylcyclopenta-2,4-dienone
AKOS000813949
2,3,4,5-tetraphenyl-2,4-cyclopentadien-1-one
AC-907/25014396
T1062
CHEBI:188913
A7317
einecs 207-530-3
2,3,4,5-tetraphenylcyclopentadienone
unii-e8ct23p8wp
nsc 2060
ai3-22092
2,3,4,5-tetraphenyl-2,4-cyclopentadienone
e8ct23p8wp ,
FT-0609356
F9995-0440
c29h20o
AB01331940-02
SCHEMBL516326
tetraphenylcyclopenta-dienone
DTXSID1060059
Q-101911
2,3,4,5-tetraphenyl-2,4-cyclopentadien-1-one #
mfcd00001407
NCGC00341026-01
Q2661932
BBL100010
AMY42106
D70532
CHEMBL4534655
tetraphenyl cyclopentadienone
CS-0072157
cyclopentadienone, tetraphenyl-
EN300-265719
tetraphenylcyclopenta-2,4-dien-1-one
SY048438

Drug Classes (1)

ClassDescription
stilbenoidAny olefinic compound characterised by a 1,2-diphenylethylene backbone.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1640018Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent 2018Science (New York, N.Y.), 12-07, Volume: 362, Issue:6419
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
AID1640019Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent 2018Science (New York, N.Y.), 12-07, Volume: 362, Issue:6419
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
acridone[no description available]medium10acridines;
cyclic ketone
ethacridine[no description available]medium10acridines
amiodarone[no description available]medium101-benzofurans;
aromatic ketone;
organoiodine compound;
tertiary amino compound		cardiovascular drug
ym 58483[no description available]medium10
camphor, (+-)-isomer[no description available]medium10bornane monoterpenoid;
cyclic monoterpene ketone		plant metabolite
carbonyl cyanide m-chlorophenyl hydrazone[no description available]medium10hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore
carbonyl cyanide p-trifluoromethoxyphenylhydrazone[no description available]medium10aromatic ether;
hydrazone;
nitrile;
organofluorine compound		ATP synthase inhibitor;
geroprotector;
ionophore
papaverine[no description available]medium10benzylisoquinoline alkaloid;
dimethoxybenzene;
isoquinolines		antispasmodic drug;
vasodilator agent
pimobendan[no description available]medium10benzimidazoles;
pyridazinone		cardiotonic drug;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
vasodilator agent
terfenadine[no description available]medium10diarylmethane
n-isopropyl-n-phenyl-4-phenylenediamine[no description available]medium10N-substituted diamineallergen;
antioxidant
3-amino-9-ethylcarbazole[no description available]medium10carbazoles
cycloguanil[no description available]medium10triazinesantifolate;
antiinfective agent;
antimalarial;
antiparasitic agent;
antiprotozoal drug;
EC 1.5.1.3 (dihydrofolate reductase) inhibitor
2,4,6-trichlorophenyl 4-nitrophenyl ether[no description available]medium10aromatic ether;
C-nitro compound;
chlorobenzenes		EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor;
herbicide
2-phenylthiazolidine-4-carboxylic acid[no description available]medium10
benz(cd)indol-2(1h)-one[no description available]medium10
3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine[no description available]medium101,2,4-triazines
honokiol[no description available]medium10biphenyls
bathophenanthroline[no description available]medium10benzenes;
phenanthrolines		chelator
2-phenyl-4,5-dichloro-3-pyridazinone[no description available]medium10
n-benzylmaleimide[no description available]medium10
phenylglycine nitrile[no description available]medium10
4,5-dimethyl-1,2-phenylenediamine[no description available]medium10
mmv665852[no description available]medium10
n-(2-methoxyphenyl)maleimide[no description available]medium10
2-aminoperimidine[no description available]medium10
1,3-bis(3-chlorophenyl)urea[no description available]medium10ureas
2-phenyl-4-oxohydroquinoline[no description available]medium10
2-chloro-3-(4-methylanilino)naphthalene-1,4-dione[no description available]medium101,4-naphthoquinones
mequindox[no description available]medium10
1,3-bis(3,5-dichlorophenyl)urea[no description available]medium10
dienestrol[no description available]medium10
cinnamoylglycine[no description available]medium10N-acylglycinemetabolite
4-(4-ethoxyphenyl)-4-oxobutanoic acid[no description available]medium10aromatic ketone
3-(4-chlorophenyl)-5-propyl-1H-pyrazolo[1,5-a]pyrimidin-7-one[no description available]medium10pyrazoles;
ring assembly
N-[4-[methyl(phenyl)sulfamoyl]phenyl]-2-thiophenecarboxamide[no description available]medium10aromatic amide
4-chloro-N-[3-cyano-4-(phenylthio)phenyl]benzamide[no description available]medium10benzamides
3-(4-morpholinyl)-4-(2-pyridinyl)-N-[3-(trifluoromethyl)phenyl]-1-pyrazolecarboxamide[no description available]medium10pyrazolopyridine
7-chloro-2-methyl-4-(4-methylphenyl)sulfonylthiazolo[5,4-b]indole[no description available]medium10sulfonamide
4-[2-[(2,6-dimethoxyphenyl)-oxomethoxy]-1-oxoethyl]-2,5-dimethyl-1H-pyrrole-3-carboxylic acid ethyl ester[no description available]medium10methoxybenzoic acid
2-(1H-benzimidazol-2-ylthio)-1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)ethanone[no description available]medium10benzimidazoles
2,3-dihydro-1,4-dioxin-5-carboxylic acid [2-[4-[4-(2-methylbutan-2-yl)phenoxy]anilino]-2-oxoethyl] ester[no description available]medium10aromatic ether
2-(1,3-benzoxazol-2-ylthio)-1-(2,5-dimethyl-1-prop-2-enyl-3-pyrrolyl)ethanone[no description available]medium10benzoxazole
3-(4-chlorophenyl)-2-methyl-3,3a,4,5-tetrahydrobenzo[g]indazole[no description available]medium10tetralins
6-hydroxy-4-methyl-2-phenyl-2,3-dihydropyridazin-3-one[no description available]medium10pyridazinone
1-(4-chlorophenyl)-3-[4-methyl-2-(thiophen-2-yl)-1,3-thiazol-5-yl]urea[no description available]medium101,3-thiazoles;
monochlorobenzenes;
phenylureas;
thiophenes
N'-[(4-chlorophenyl)-oxomethyl]-2-methyl-4-thiazolecarbohydrazide[no description available]medium10carbonyl compound;
organohalogen compound
bi-78d3[no description available]medium10aryl sulfide
n-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide[no description available]medium10anilide fungicide;
monocarboxylic acid amide;
monochlorobenzenes;
organosulfur compound;
thiadiazoles		antifungal agrochemical
N'2-[3-(trifluoromethyl)benzoyl]-3-aminopyrazine-2-carbohydrazide[no description available]medium10(trifluoromethyl)benzenes
2-amino-4-(2-chlorophenyl)-6-[(4-chlorophenyl)thio]pyridine-3,5-dicarbonitrile[no description available]medium10phenylpyridine
2-[5-[(3-chlorophenyl)thio]-2-thiophenyl]pyridine[no description available]medium10aryl sulfide
8-methylsulfinyl-4,5-dihydrothieno[3,4-g][2,1]benzoxazole-6-carboxylic acid ethyl ester[no description available]medium10thiophenecarboxylic acid
1-(5-tert-butyl-2-methyl-3-pyrazolyl)-3-(3,5-dichlorophenyl)urea[no description available]medium10ureas
4-[[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-7-methyl-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]methyl]morpholine[no description available]medium10isoquinolines
7-chloro-3-hydroxy-2-[3-(trifluoromethyl)phenyl]-4-quinazolinone[no description available]medium10quinazolines
2-(1H-benzimidazol-2-ylthio)-1-[2,5-dimethyl-1-(2-oxolanylmethyl)-3-pyrrolyl]ethanone[no description available]medium10benzimidazoles
ethyl 4-(3-oxo-2,3-dihydroisothiazol-2-yl)benzoate[no description available]medium10organic molecular entity
7-chloro-N-(phenylmethyl)-4-quinolinamine[no description available]medium10aminoquinoline
6-methoxy-2-methyl-N-[[3-(trifluoromethyl)phenyl]methyl]-4-quinolinamine[no description available]medium10aminoquinoline
2-acetylpyridine thiosemicarbazone[no description available]medium10
1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea[no description available]medium10
4-(4-chlorophenyl)-3-methylbut-3-en-2-oxime[no description available]medium10
cyclopentane[no description available]medium40cycloalkane;
cyclopentanes;
volatile organic compound		non-polar solvent
carbon monoxide[no description available]medium10carbon oxide;
gas molecular entity;
one-carbon compound		biomarker;
EC 1.9.3.1 (cytochrome c oxidase) inhibitor;
human metabolite;
ligand;
metabolite;
mitochondrial respiratory-chain inhibitor;
mouse metabolite;
neurotoxin;
neurotransmitter;
P450 inhibitor;
probe;
signalling molecule;
vasodilator agent
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
diethylstilbestrol[no description available]low00stilbenoid
hexestrol[no description available]low00stilbenoid
3,3',4,5'-tetrahydroxystilbene[no description available]low00stilbenoid
sarpogrelate[no description available]low00hemisuccinate;
stilbenoid
2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine[no description available]low00stilbenoid
2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine[no description available]low00stilbenoid
triphenylethylene[no description available]low00stilbenoid
ethamoxytriphetol[no description available]low00stilbenoid
triparanol[no description available]low00stilbenoidanticoronaviral agent
iodoalphionic acid[no description available]low00stilbenoid
norpropoxyphene[no description available]low00stilbenoid
2,3,3-triphenylacrylonitrile[no description available]low00stilbenoid
remacemide[no description available]low00stilbenoid
4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol[no description available]low00stilbenoid
hexestrol bis(diethylaminoethyl ether)[no description available]low00stilbenoid
1-(4-hydroxyphenyl)-2-phenylethan-1-one[no description available]low00stilbenoid
o-desmethylangolensin[no description available]low00stilbenoid
4,5-diphenyl-1,5-dihydroimidazol-2-one[no description available]low00stilbenoid
3,3'-Dihydroxyhexestrol[no description available]low00stilbenoid
lunularic acid[no description available]low00stilbenoid
lunularin[no description available]low00stilbenoid
diphenidine[no description available]low00stilbenoid
nutlin 3[no description available]low00stilbenoid
1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)ethanone[no description available]low00stilbenoid
sc 57666[no description available]low00stilbenoid
lephetamine[no description available]low00stilbenoid
pallidol[no description available]low00carbopolycyclic compound;
polyphenol;
stilbenoid		antifungal agent;
antioxidant;
plant metabolite
1-(4-bromophenyl)-2-phenylethan-1-one[no description available]low00stilbenoid
vedelianin[no description available]low00cyclic ether;
organic heterotricyclic compound;
resorcinols;
stilbenoid		antineoplastic agent;
plant metabolite
2-(2-chloro-6-fluorophenyl)-1-(2,4-dihydroxyphenyl)ethanone[no description available]low00stilbenoid
2-(3,4-dimethoxyphenyl)-1-(2,4,6-trihydroxyphenyl)ethanone[no description available]low00stilbenoid
1-(3,4-dimethoxy-2-methylphenyl)-2-(3,4-dimethoxyphenyl)ethanone[no description available]low00stilbenoid
zuclomiphene[no description available]low00stilbenoid
2-(4-bromophenyl)-1-(2,4-dihydroxyphenyl)ethanone[no description available]low00stilbenoid
5-[2-(4-ethoxy-2-hydroxyphenyl)-2-oxoethyl]-2-benzofurancarboxylic acid[no description available]low00stilbenoid
tamoxifen[no description available]low00stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
ly 288513[no description available]low00stilbenoid
2-[(4,7-dimethyl-2-quinazolinyl)thio]-1,2-diphenylethanone[no description available]low00stilbenoid
dimethylstilbestrol[no description available]low00stilbenoid
toremifene citrate[no description available]low00stilbenoidanticoronaviral agent
droloxifene[no description available]low00stilbenoid
1-(4-hydroxyphenyl)-1,2-diphenyl-1-butene[no description available]low00stilbenoid
idoxifene[no description available]low00stilbenoid
n-desmethyltoremifene[no description available]low00stilbenoid
desdimethyltamoxifen[no description available]low00stilbenoid
alpha-hydroxytamoxifen[no description available]low00stilbenoid
2-chloro-N-(1,2-diphenylethyl)acetamide[no description available]low00stilbenoid
resveratrol-4'-o-glucuronide[no description available]low00glycoside;
stilbenoid
astringin[no description available]low00beta-D-glucoside;
monosaccharide derivative;
polyphenol;
stilbenoid		antineoplastic agent;
antioxidant;
metabolite
isorhapontin[no description available]low00glycoside;
stilbenoid
trans-2,3',4,5'-tetrahydroxystilbene[no description available]low00stilbenoid
polydatin[no description available]low00beta-D-glucoside;
monosaccharide derivative;
polyphenol;
stilbenoid		anti-arrhythmia drug;
antioxidant;
geroprotector;
hepatoprotective agent;
metabolite;
nephroprotective agent;
potassium channel modulator
Pinosylvin methyl ether[no description available]low00stilbenoid
epsilon-viniferin[no description available]low001-benzofurans;
polyphenol;
stilbenoid		metabolite
salvianolic acid a[no description available]low00stilbenoid
4-acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid[no description available]low00stilbenoid
(+)-trans-epsilon-viniferin[no description available]low001-benzofurans;
polyphenol;
stilbenoid
desoxyrhaponticin[no description available]low00glycoside;
stilbenoid
3,5-dimethoxy-trans-stilbene[no description available]low00stilbenoid
quadrangularin a[no description available]low00indanes;
polyphenol;
stilbenoid		antioxidant;
plant metabolite
isorhapontigenin[no description available]low00stilbenoid
rhapontigenin[no description available]low00stilbenoid
(E)-2,3,5,4'-tetrahydroxystilbene-2-O-beta-D-glucoside[no description available]low00beta-D-glucoside;
resorcinols;
stilbenoid		anti-inflammatory agent;
antioxidant;
apoptosis inhibitor;
cardioprotective agent;
cyclooxygenase 2 inhibitor;
platelet aggregation inhibitor
fosbretabulin[no description available]low00stilbenoid
n-desmethyltamoxifen[no description available]low00stilbenoid
mulberroside a[no description available]low00glycoside;
stilbenoid
cajanine[no description available]low00stilbenoid
metaflumizone[no description available]low00semicarbazone;
stilbenoid
bms453[no description available]low00benzoic acids;
dihydronaphthalenes;
stilbenoid		retinoic acid receptor alpha antagonist;
retinoic acid receptor beta agonist;
retinoic acid receptor gamma antagonist;
teratogenic agent
gw 4064[no description available]low00stilbenoid
bms 204493[no description available]low00acetylenic compound;
benzoic acids;
dihydronaphthalenes;
stilbenoid		retinoic acid receptor antagonist
4-hydroxy-n-desmethyltamoxifen[no description available]low00stilbenoid
delta-viniferin[no description available]low001-benzofurans;
polyphenol;
stilbenoid
palovarotene[no description available]low00stilbenoid
aiphanol[no description available]low00aromatic ether;
benzodioxine;
lignan;
stilbenoid		EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
batatasin-iii[no description available]low00stilbenoid
n-(3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl)-2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)oxy)propanamide[no description available]low00stilbenoid
nutlin-3a[no description available]low00stilbenoid
bay94 9172[no description available]low00(18)F radiopharmaceutical;
aromatic ether;
polyether;
secondary amino compound;
stilbenoid;
substituted aniline		radioactive imaging agent
3-[[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(2-methoxyphenyl)-3,4-dihydropyrazol-3-yl]-oxomethyl]-2-oxazolidinone[no description available]low00stilbenoid
schweinfurthin g[no description available]low00cyclic ether;
organic heterotricyclic compound;
resorcinols;
stilbenoid		antineoplastic agent;
metabolite
schweinfurthin f[no description available]low00cyclic ether;
organic heterotricyclic compound;
resorcinols;
stilbenoid		metabolite
amorfrutin a[no description available]low00stilbenoid
3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid[no description available]low00stilbenoid
ConditionIndicatedRelationship StrengthStudiesTrials
Infections, Plasmodium0low10
Malaria0low10
Marsh Fever0low10
Paludism0low10
Plasmodium Infections0low10
Remittent Fever0low10