Page last updated: 2024-08-18

tecnazene and Disease Models, Animal

tecnazene has been researched along with Disease Models, Animal in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's0 (0.00)18.2507
2000's2 (11.76)29.6817
2010's11 (64.71)24.3611
2020's3 (17.65)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Arai, I; Futaki, N; Harada, M; Hashimoto, Y; Honma, Y; Nakaike, S; Sugimoto, M; Takahashi, N1
Granzier, HL; Hwee, DT; Kolb, J; Lee, EJ; Malik, FI1
Granzier, H; Karimi, E; Kolb, J; Lee, EJ; Lindqvist, J1
Bendahan, D; Bernard, M; Gineste, C; Gondin, J; Granzier, H; Hourani, Z; Ogier, AC; Varlet, I1
Bakker, AJ; Clayton, JS; Goullee, H; Griffiths, LM; Harries, R; Laing, NG; Laitila, JM; Lawlor, MW; McNamara, EL; Nowak, KJ; Ochala, J; Ottenheijm, CAC; Pelin, K; Ravenscroft, G; Ross, JA; Sewry, C; Taylor, RL; van der Pijl, R; Wallgren-Pettersson, C; Wingate, CD1
Barton, ER; Granzier, H; Li, F1
Beggs, AH; Buck, D; de Winter, JM; Ferrara, C; Granzier, H; Jasper, JR; Labeit, S; Lawlor, MW; Malik, FI; Meng, H; Ottenheijm, CA; Piroddi, N; Poggesi, C; Stienen, GJ; Tesi, C1
Fowler, VM; Gokhin, DS; Sacco, A; Sui, Z; Tierney, MT1
Bassel-Duby, R; Beetz, N; Bezprozvannaya, S; Chen, S; Doering, J; Garg, A; Grange, RW; Laing, NG; Li, L; Long, C; Nelson, BR; O'Rourke, J; Olson, EN; Ravenscroft, G1
Birch, C; Buck, D; De Winter, J; Escobar, YN; Granzier, HL; Kolb, J; Konhilas, J; Lawlor, MW; Li, F; Meng, H; Ottenheijm, C; Slater, R; Smith, JE; Yang, L1
de Winter, JM; Granzier, H; Joureau, B; Ottenheijm, CA; Stam, K1
Brooks, SV; Dowling, JJ; Nelson, DD; Telfer, WR; Waugh, T1
Laing, NG; Nowak, KJ; Sewry, CA; Wallgren-Pettersson, C1
Bendahan, D; Brohm, K; Cozzone, PJ; De Winter, JM; Giannesini, B; Gineste, C; Gondin, J; Granzier, H; Gretz, N; Jubeau, M; Kohl, C; Labeit, S; Le Fur, Y; Ottenheijm, CA; Pecchi, E; Stienen, GJ; Vilmen, C; Witt, CC1
Laing, NG; Wallgren-Pettersson, C1
Brown, RH; Hoffman, EP; Kunkel, LM1

Reviews

1 review(s) available for tecnazene and Disease Models, Animal

ArticleYear
Nemaline myopathies.
    Seminars in pediatric neurology, 2011, Volume: 18, Issue:4

    Topics: Animals; Disease Models, Animal; DNA Mutational Analysis; Humans; Molecular Diagnostic Techniques; Muscle Proteins; Muscle, Skeletal; Mutation; Myopathies, Nemaline

2011

Other Studies

16 other study(ies) available for tecnazene and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Scratching behavior in spontaneous- or allergic contact-induced dermatitis in NC/Nga mice.
    Experimental dermatology, 2005, Volume: 14, Issue:11

    Topics: Animals; Behavior, Animal; Dermatitis; Dermatitis, Allergic Contact; Disease Models, Animal; Epidermis; Mice; Mice, Inbred Strains; Nitrobenzenes; Skin; Time Factors; Water Loss, Insensible

2005
Functional Characterization of the Intact Diaphragm in a Nebulin-Based Nemaline Myopathy (NM) Model-Effects of the Fast Skeletal Muscle Troponin Activator
    International journal of molecular sciences, 2019, Oct-10, Volume: 20, Issue:20

    Topics: Animals; Copper Transporter 1; Diaphragm; Disease Models, Animal; Imidazoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Myopathies, Nemaline; Pyrazines; Troponin

2019
Omecamtiv mecarbil lowers the contractile deficit in a mouse model of nebulin-based nemaline myopathy.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Animals; Calcium; Disease Models, Animal; Mice; Mice, Knockout; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Proteins; Myopathies, Nemaline; Urea

2019
In vivo characterization of skeletal muscle function in nebulin-deficient mice.
    Muscle & nerve, 2020, Volume: 61, Issue:3

    Topics: Animals; Disease Models, Animal; Female; Hindlimb; Mice, Knockout; Muscle Contraction; Muscle Fatigue; Muscle Proteins; Muscle, Skeletal; Myopathies, Nemaline; Myosin Heavy Chains

2020
Nebulin nemaline myopathy recapitulated in a compound heterozygous mouse model with both a missense and a nonsense mutation in Neb.
    Acta neuropathologica communications, 2020, 02-17, Volume: 8, Issue:1

    Topics: Animals; Codon, Nonsense; Disease Models, Animal; Female; Male; Mice, Inbred C57BL; Muscle Proteins; Muscle, Skeletal; Mutation, Missense; Myopathies, Nemaline

2020
Deleting nebulin's C-terminus reveals its importance to sarcomeric structure and function and is sufficient to invoke nemaline myopathy.
    Human molecular genetics, 2019, 05-15, Volume: 28, Issue:10

    Topics: Actin Cytoskeleton; Amino Acid Sequence; Animals; Animals, Newborn; Disease Models, Animal; Homozygote; Humans; Hypertrophy; Insulin-Like Growth Factor I; Mice; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Phenotype; Sarcomeres

2019
Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 6

    Topics: Animals; Disease Models, Animal; Exons; Gene Deletion; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Proteins; Muscle Weakness; Myopathies, Nemaline; Severity of Illness Index

2013
Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle.
    Molecular biology of the cell, 2014, Volume: 25, Issue:6

    Topics: Actin Cytoskeleton; Actinin; Actins; Animals; Calpain; Disease Models, Animal; Mice; Mice, Inbred mdx; Muscle Proteins; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Protein Structure, Tertiary; Proteolysis; Tropomodulin

2014
KLHL40 deficiency destabilizes thin filament proteins and promotes nemaline myopathy.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:8

    Topics: Animals; Animals, Newborn; Cytoskeletal Proteins; Disease Models, Animal; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Proteins; Muscle, Skeletal; Myopathies, Nemaline; Protein Interaction Domains and Motifs; Protein Stability; Proteolysis; Sarcomeres; Ubiquitination

2014
Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy.
    Human molecular genetics, 2015, Sep-15, Volume: 24, Issue:18

    Topics: Animals; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Mice; Mice, Knockout; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Myosins; Phenotype; Sarcomeres

2015
Muscle weakness in respiratory and peripheral skeletal muscles in a mouse model for nebulin-based nemaline myopathy.
    Neuromuscular disorders : NMD, 2017, Volume: 27, Issue:1

    Topics: Animals; Diaphragm; Disease Models, Animal; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Respiratory Insufficiency

2017
Neb: a zebrafish model of nemaline myopathy due to nebulin mutation.
    Disease models & mechanisms, 2012, Volume: 5, Issue:3

    Topics: Actin Cytoskeleton; Amino Acid Sequence; Animals; Disease Models, Animal; Embryo, Nonmammalian; Humans; Larva; Molecular Sequence Data; Motor Activity; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Phenotype; RNA Processing, Post-Transcriptional; Zebrafish; Zebrafish Proteins

2012
In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
    Neuromuscular disorders : NMD, 2013, Volume: 23, Issue:4

    Topics: Animals; Disease Models, Animal; Gene Expression; Heterozygote; In Vitro Techniques; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Muscle Proteins; Muscle Strength; Muscle Weakness; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Phenotype; Severity of Illness Index

2013
138th ENMC Workshop: nemaline myopathy, 20-22 May 2005, Naarden, The Netherlands.
    Neuromuscular disorders : NMD, 2006, Volume: 16, Issue:1

    Topics: Animals; Disease Models, Animal; Humans; Muscle Proteins; Myopathies, Nemaline; Netherlands

2006
Dystrophin: the protein product of the Duchenne muscular dystrophy locus.
    Cell, 1987, Dec-24, Volume: 51, Issue:6

    Topics: Animals; Disease Models, Animal; Dystrophin; Genes; Humans; Male; Mice; Molecular Weight; Muscle Proteins; Muscle, Smooth; Muscles; Muscular Dystrophies; Myocardium; Recombinant Fusion Proteins

1987