tecnazene has been researched along with Muscle Weakness in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 13 (72.22) | 24.3611 |
| 2020's | 3 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Beatka, MJ; Geurts, AM; Granzier, H; Heisner, J; Hill, RB; Lawlor, MW; Meng, H; Montanaro, F; Ott, E; Prom, MJ; Slick, RA; Stowe, DF; Sutton, J; Tinklenberg, JA; Toro, R; Vanden Avond, M; Zhang, L | 1 |
| Chaoui, R; Dittmayer, C; Englert, B; Goebel, HH; Korinth, D; Pelin, K; Rocha, ML; Rossi, R; Schlembach, D; Schmid, S; Schuelke, M; Stenzel, W; Suk, EK; Uruha, A | 1 |
| Gardberg, M; Hackman, P; Jokela, M; Kiiski, K; Lehtokari, VL; Pelin, K; Sagath, L; Udd, B; Välipakka, S; Vihola, A; Wallgren-Pettersson, C | 1 |
| Kim, DS; Lee, JM; Lim, JG; Park, YE; Shin, JH | 1 |
| Granzier, HL; Irving, TC; Kiss, B; Lee, EJ; Li, FW; Ma, W; Mijailovich, SM; Tonino, P | 1 |
| Aller, E; Aparisi, MJ; Calabria, I; Cardona-Gay, C; Cervera, JV; Gonzalez-Tarancon, L; Martinez-Matilla, M; Millan, JM; Moreau-Le Lan, S; Muelas, N; Pedrola, L; Pitarch, I; Sagath, L; Selles, J | 1 |
| Ayres, S; Beatka, MJ; Fickau, BA; Granzier, HL; Lawlor, MW; Meng, H; Siebers, EM; Simpson, P; Tinklenberg, JA; Yang, L | 1 |
| Barton, ER; Granzier, H; Li, F | 1 |
| Beggs, AH; Buck, D; de Winter, JM; Ferrara, C; Granzier, H; Jasper, JR; Labeit, S; Lawlor, MW; Malik, FI; Meng, H; Ottenheijm, CA; Piroddi, N; Poggesi, C; Stienen, GJ; Tesi, C | 1 |
| Bellance, R; Böhm, J; De Winter, JM; Estournet, B; Eymard, B; Fardeau, M; Laporte, J; Lehtokari, VL; Lubieniecki, F; Madelaine, A; Malfatti, E; Monges, S; Ottenheijm, CA; Pelin, K; Quijano-Roy, S; Romero, NB; Schäffer, U; Taratuto, AL; Viou, MT; Wallgren-Pettersson, C; Wu, B | 1 |
| Choi, VN; Jeong, SY; Jin, HS; Kim, JS; Kim, K; Lee, JB; Lee, KY; Yim, SY | 1 |
| Birch, C; Buck, D; De Winter, J; Escobar, YN; Granzier, HL; Kolb, J; Konhilas, J; Lawlor, MW; Li, F; Meng, H; Ottenheijm, C; Slater, R; Smith, JE; Yang, L | 1 |
| de Winter, JM; Granzier, H; Joureau, B; Ottenheijm, CA; Stam, K | 1 |
| Abe, K; Hishikawa, N; Motokura, E; Nishikawa, A; Nishino, I; Ohta, Y; Sato, K; Takahashi, Y; Takemoto, M; Tsunoda, K; Yamashita, T | 1 |
| Beggs, AH; Granzier, H; Labeit, S; Ottenheijm, CA; Stienen, GJ; Witt, CC | 1 |
| Feng, HZ; Iwamoto, H; Jin, JP; Larsson, L; Lehtokari, VL; Li, M; Ochala, J; Pénisson-Besnier, I; Wallgren-Pettersson, C; Yagi, N | 1 |
| Bendahan, D; Brohm, K; Cozzone, PJ; De Winter, JM; Giannesini, B; Gineste, C; Gondin, J; Granzier, H; Gretz, N; Jubeau, M; Kohl, C; Labeit, S; Le Fur, Y; Ottenheijm, CA; Pecchi, E; Stienen, GJ; Vilmen, C; Witt, CC | 1 |
| Hackman, P; Kalimo, H; Lehtokari, VL; Nuutinen, E; Paetau, A; Pelin, K; Sewry, C; Udd, B; Wallgren-Pettersson, C | 1 |
18 other study(ies) available for tecnazene and Muscle Weakness
| Article | Year |
|---|---|
Aberrations in Energetic Metabolism and Stress-Related Pathways Contribute to Pathophysiology in the Neb Conditional Knockout Mouse Model of Nemaline Myopathy.
Topics: Animals; Humans; Mice; Mice, Knockout; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Proteomics | 2023 |
A novel mutation in NEB causing foetal nemaline myopathy with arthrogryposis during early gestation.
Topics: Arthrogryposis; Female; Fetus; Gestational Age; Humans; Lebanon; Male; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Pregnancy; Ultrasonography, Prenatal | 2021 |
Congenital asymmetric distal myopathy with hemifacial weakness caused by a heterozygous large de novo mosaic deletion in nebulin.
Topics: Adult; Biopsy; Distal Myopathies; Exons; Facial Muscles; Female; Finland; Heterozygote; Humans; Mosaicism; Muscle Proteins; Muscle Weakness; Mutation; Myotonia Congenita; Pedigree; Sequence Deletion | 2021 |
Clinical and genetic diversity of nemaline myopathy from a single neuromuscular center in Korea.
Topics: Adolescent; Adult; Child; Child, Preschool; DNA Copy Number Variations; Exome Sequencing; Female; Genotyping Techniques; Humans; Infant; Lower Extremity; Male; Muscle Proteins; Muscle Weakness; Mutation; Myopathies, Nemaline; Republic of Korea; Young Adult | 2017 |
Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle.
Topics: Actin Cytoskeleton; Animals; Cells, Cultured; Mice; Mice, Knockout; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myosins; Tropomyosin; Troponin | 2018 |
New mutations found by Next-Generation Sequencing screening of Spanish patients with Nemaline Myopathy.
Topics: Actins; Adult; Alleles; Child; Female; Gene Frequency; High-Throughput Nucleotide Sequencing; Humans; Male; Muscle Hypotonia; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Pedigree; RNA Splicing; Spain | 2018 |
Myostatin Inhibition Using ActRIIB-mFc Does Not Produce Weight Gain or Strength in the Nebulin Conditional KO Mouse.
Topics: Activin Receptors, Type II; Animals; Mice; Mice, Knockout; Muscle Proteins; Muscle Strength; Muscle Weakness; Myopathies, Nemaline; Myostatin; Weight Gain | 2019 |
Deleting nebulin's C-terminus reveals its importance to sarcomeric structure and function and is sufficient to invoke nemaline myopathy.
Topics: Actin Cytoskeleton; Amino Acid Sequence; Animals; Animals, Newborn; Disease Models, Animal; Homozygote; Humans; Hypertrophy; Insulin-Like Growth Factor I; Mice; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Phenotype; Sarcomeres | 2019 |
Deleting exon 55 from the nebulin gene induces severe muscle weakness in a mouse model for nemaline myopathy.
Topics: Animals; Disease Models, Animal; Exons; Gene Deletion; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle Proteins; Muscle Weakness; Myopathies, Nemaline; Severity of Illness Index | 2013 |
Muscle histopathology in nebulin-related nemaline myopathy: ultrastrastructural findings correlated to disease severity and genotype.
Topics: Adolescent; Child; Child, Preschool; DNA Mutational Analysis; Female; Genotype; Humans; Infant; Infant, Newborn; Male; Microscopy, Electron; Muscle Contraction; Muscle Proteins; Muscle Weakness; Muscles; Myopathies, Nemaline; Myosin Heavy Chains; Myosins; Severity of Illness Index; Young Adult | 2014 |
Identification of the rare compound heterozygous variants in the NEB gene in a Korean family with intellectual disability, epilepsy and early-childhood-onset generalized muscle weakness.
Topics: Adolescent; Age of Onset; Child; DNA Copy Number Variations; Epilepsy; Exome; Female; Heterozygote; Humans; Intellectual Disability; Male; Muscle Proteins; Muscle Weakness; Pedigree; Republic of Korea; Sequence Analysis, DNA; Young Adult | 2014 |
Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy.
Topics: Animals; Disease Models, Animal; Gene Expression; Gene Expression Profiling; Mice; Mice, Knockout; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Myosins; Phenotype; Sarcomeres | 2015 |
Muscle weakness in respiratory and peripheral skeletal muscles in a mouse model for nebulin-based nemaline myopathy.
Topics: Animals; Diaphragm; Disease Models, Animal; Mice; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myopathies, Nemaline; Respiratory Insufficiency | 2017 |
A patient with slowly progressive adult-onset nemaline myopathy and novel compound heterozygous mutations in the nebulin gene.
Topics: Diagnosis, Differential; Disease Progression; Heterozygote; Humans; Male; Middle Aged; Muscle Proteins; Muscle Weakness; Mutation; Myopathies, Nemaline; Respiratory Insufficiency | 2017 |
Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency.
Topics: Adolescent; Animals; Child; Child, Preschool; Female; Humans; Infant; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Myofibrils; Myopathies, Nemaline; Sarcomeres | 2009 |
Disrupted myosin cross-bridge cycling kinetics triggers muscle weakness in nebulin-related myopathy.
Topics: Adult; Gene Expression Regulation; Humans; Kinetics; Male; Middle Aged; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Myosins; X-Ray Diffraction | 2011 |
In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Topics: Animals; Disease Models, Animal; Gene Expression; Heterozygote; In Vitro Techniques; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Knockout; Muscle Proteins; Muscle Strength; Muscle Weakness; Muscle, Skeletal; Mutation; Myopathies, Nemaline; Phenotype; Severity of Illness Index | 2013 |
Distal myopathy caused by homozygous missense mutations in the nebulin gene.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biopsy; Distal Myopathies; Female; Fingers; Humans; Leg; Male; Microscopy, Electron; Middle Aged; Muscle Fibers, Skeletal; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; Mutation, Missense; Pedigree; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational | 2007 |