Page last updated: 2024-09-27

Central Core Disease

An inherited congenital myopathic condition characterized by weakness and hypotonia in infancy and delayed motor development. Muscle biopsy reveals a condensation of myofibrils and myofibrillar material in the central portion of each muscle fiber. (Adams et al., Principles of Neurology, 6th ed, p1452)

Synonyms(5)

Synonym
Central Core Disease
Central Core Disease of Muscle
Myopathy, Central Core
Central Core Myopathy
Shy-Magee Syndrome

Research Excerpts

Overview

ExcerptReference
"Central core disease is a congenital myopathy with muscle weakness defined pathologically by the presence of extensive areas in muscle fibres that are devoid of oxidative enzyme activity."( Davis, M; Dove, J; Dwyer, JS; Evans, G; Fürst, D; Helliwell, T; Laing, N; Müller, C; Quinlivan, RC; Schröder, R; Sewry, CA, 2002)
"Central core disease is a congenital myopathy characterized by generalized hypotonia, muscle weakness and presence of central cores on muscle biopsy."( Gulati, S; Kalra, V; Salhotra, A; Sarkar, C; Sharma, MC, 2004)
"Central core disease is a myopathy often arising from mutations in the type 1 ryanodine receptor (RYR1) gene, encoding the sarcoplasmic reticulum calcium release channel RyR1."( Beley, C; Brocard, J; Denarier, E; Fauré, J; Fourest-Lieuvin, A; Garcia, L; Gilbert-Dussardier, B; Lunardi, J; Marty, I; Monnier, N; Perez, MJ; Piétri-Rouxel, F; Rendu, J; Romero, N; Roux-Buisson, N, 2013)

Research

Studies (60)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's36 (60.00)18.1394
2010's22 (36.67)28.8240
2020's2 (3.33)9.53
DrugIndicatedRelationship StrengthStudiesTrials
glycine0low10
chlorocresol0low20
albuterol0medium21
caffeine0low80
carvedilol0low10
dantrolene0low10
diazepam0low10
fentanyl0low10
glyburide0low10
halothane0low50
lorazepam0low10
propofol0low20
succinylcholine0low20
cycloheximide0low10
threonine0low10
tryptophan0low10
isoleucine0low10
arginine0low10
pyrroles0low10
tecnazene0low10
azacitidine0low10
hematoxylin0low10
ethylnitrosourea0low10
4-chloro-2-cresol0low10
glutamic acid0low10
remifentanil0low20
atorvastatin0low10
cathinone0low10
ropivacaine0low10
oxytocin0low10
ryanodine0low50
trichostatin a0low10
thapsigargin0low10
decitabine0low10
mivacurium0low10
oxalates0low10
nad0low10
piperidines0low20
cyclosporine0low10

Protein Targets (657)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
GLI family zinc finger 3130013
nuclear receptor subfamily 1, group I, member 39009
estrogen-related nuclear receptor alpha150015
estrogen nuclear receptor alpha170017
vitamin D (1,25- dihydroxyvitamin D3) receptor6006
thyroid hormone receptor beta isoform 29009
nuclear factor erythroid 2-related factor 2 isoform 1100010
Androgen receptor0101
Nuclear receptor ROR-gamma4004
glp-1 receptor, partial5005
thioredoxin reductase8008
GLS protein9009
regulator of G-protein signaling 45005
NPYLR7B0011
arylsulfatase A5005
euchromatic histone-lysine N-methyltransferase 2140014
thyroid stimulating hormone receptor5005
flap endonuclease 14004
peripheral myelin protein 223003
ATP-binding cassette sub-family C member 30606
Multidrug resistance-associated protein 40606
Bile salt export pump0808
Beta-2 adrenergic receptor0437
Beta-1 adrenergic receptor0235
60 kDa chaperonin0101
60 kDa heat shock protein, mitochondrial0101
Beta-3 adrenergic receptor0224
Delta-type opioid receptor0213
10 kDa heat shock protein, mitochondrial0101
Thiosulfate sulfurtransferase0101
Beta-2 adrenergic receptor 0013
60 kDa chaperonin 0101
10 kDa chaperonin 0101
Beta-2 adrenergic receptor0123
Canalicular multispecific organic anion transporter 10404
ATP-dependent phosphofructokinase9009
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE6006
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN0011
phosphopantetheinyl transferase6006
NFKB1 protein, partial2002
thyroid stimulating hormone receptor5005
alpha-galactosidase1001
cytochrome P450 2C19 precursor2002
chromobox protein homolog 19009
DNA polymerase iota isoform a (long)4004
muscarinic acetylcholine receptor M15005
lethal factor (plasmid)4004
Cytochrome P450 3A40001
Nitric oxide synthase, endothelial0002
Nitric oxide synthase, brain0001
Nitric oxide synthase, brain 0001
Nitric oxide synthase, inducible0001
Nitric oxide synthase, inducible0013
Cationic amino acid transporter 30101
Chain A, Cruzipain2002
RAR-related orphan receptor gamma8008
SMAD family member 23003
SMAD family member 33003
AR protein120012
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)5005
glucocorticoid receptor [Homo sapiens]120012
retinoic acid nuclear receptor alpha variant 18008
retinoid X nuclear receptor alpha7007
pregnane X nuclear receptor8008
peroxisome proliferator-activated receptor delta6006
peroxisome proliferator activated receptor gamma7007
caspase-32002
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a7007
Caspase-71001
vitamin D3 receptor isoform VDRA3003
thyroid hormone receptor beta isoform a3003
caspase-31001
geminin6006
Voltage-dependent calcium channel gamma-2 subunit5005
Solute carrier organic anion transporter family member 2B1 0002
3-hydroxy-3-methylglutaryl-coenzyme A reductase0202
Cellular tumor antigen p538008
ATP-dependent translocase ABCB10304
Insulin receptor 0101
Glutamate receptor 25218
Dipeptidyl peptidase 40101
Prostaglandin G/H synthase 20101
3-hydroxy-3-methylglutaryl-coenzyme A reductase 0101
Histone deacetylase 10327
Histone deacetylase 20316
Solute carrier organic anion transporter family member 1B30001
Histone deacetylase 60316
Broad substrate specificity ATP-binding cassette transporter ABCG20303
Solute carrier organic anion transporter family member 1B10203
Chain A, Beta-lactamase2002
interleukin 83003
pregnane X receptor3003
ATAD5 protein, partial6006
Fumarate hydratase3003
PPM1D protein5005
TDP1 protein9009
Thrombopoietin1001
Smad32002
aldehyde dehydrogenase 1 family, member A16006
progesterone receptor8008
cytochrome P450 family 3 subfamily A polypeptide 49009
farnesoid X nuclear receptor6006
polyprotein3003
67.9K protein4004
Parkin3003
IDH12002
aryl hydrocarbon receptor4004
activating transcription factor 65005
Bloom syndrome protein isoform 14004
peripheral myelin protein 22 isoform 13003
hemoglobin subunit beta1001
cellular tumor antigen p53 isoform a3003
huntingtin isoform 21001
ras-related protein Rab-9A3003
serine/threonine-protein kinase mTOR isoform 13003
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
histone acetyltransferase KAT2A isoform 12002
lamin isoform A-delta106006
Interferon beta9009
Integrin beta-32114
Integrin alpha-IIb2114
Adenosine receptor A30202
DNA (cytosine-5)-methyltransferase 10202
Adenosine receptor A2a0315
Adenosine receptor A10215
D(1A) dopamine receptor3003
Spike glycoprotein2013
Multidrug and toxin extrusion protein 10202
Histone-lysine N-methyltransferase EHMT20202
ATPase family AAA domain-containing protein 54004
Ataxin-26006
Chain A, Glycogen Phosphorylase0101
Chain A, Glycogen phosphorylase, liver form0011
Chain A, glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Glycogen phosphorylase, liver form0011
Chain A, Chitinase0101
v-jun sarcoma virus 17 oncogene homolog (avian)4004
atrial natriuretic peptide receptor 1 precursor2002
DNA polymerase beta2002
nuclear receptor ROR-gamma isoform 16006
DNA polymerase kappa isoform 13003
Potassium channel subfamily K member 20123
Glycogen phosphorylase, muscle form0101
Renin0101
Carbonic anhydrase 10204
Carbonic anhydrase 20204
Cholinesterase0101
Glycogen phosphorylase, liver form0101
Glycogen phosphorylase, muscle form0101
Replicase polyprotein 1ab0112
Replicase polyprotein 1ab0112
Amine oxidase [flavin-containing] A0202
Acetylcholinesterase0101
Adenosine receptor A10203
Amine oxidase [flavin-containing] B0303
cAMP-specific 3',5'-cyclic phosphodiesterase 4A0101
Adenosine receptor A30101
Adenosine receptor A2b0102
Adenosine receptor A2b0203
Adenosine receptor A2a0204
Vasopressin V2 receptor0001
Serine/threonine-protein kinase mTOR0101
Adenosine receptor A2a0101
Adenosine receptor A10101
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0101
DNA-dependent protein kinase catalytic subunit0101
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B0101
Adenylate cyclase type 10001
Chitotriosidase-10101
Serine-protein kinase ATM0101
Serine/threonine-protein kinase ATR0101
Adenosine receptor A2b0102
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C0101
Palmitoleoyl-protein carboxylesterase NOTUM0123
Endochitinase B10101
Muscarinic acetylcholine receptor0001
Phosphodiesterase 0101
Guanine deaminase0101
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain A, 2-oxoglutarate Oxygenase3003
Microtubule-associated protein tau5005
EWS/FLI fusion protein3003
bromodomain adjacent to zinc finger domain 2B3003
lysosomal alpha-glucosidase preproprotein2002
D(1A) dopamine receptor4004
mitogen-activated protein kinase 12002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
short transient receptor potential channel 6 isoform 10011
Toll-like receptor 40101
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0202
5-hydroxytryptamine receptor 40404
Amyloid-beta precursor protein0101
Aldo-keto reductase family 1 member B10404
Alpha-2A adrenergic receptor0202
Neuronal acetylcholine receptor subunit alpha-41102
Neuronal acetylcholine receptor subunit beta-21102
Angiotensin-converting enzyme0202
D(2) dopamine receptor0303
Alpha-2B adrenergic receptor0202
Alpha-2C adrenergic receptor0202
5-hydroxytryptamine receptor 1A0527
D(1A) dopamine receptor0202
UDP-glucuronosyltransferase 1A1 0101
Sodium-dependent noradrenaline transporter 0404
Alpha-1D adrenergic receptor0202
5-hydroxytryptamine receptor 2A0202
5-hydroxytryptamine receptor 2C0404
5-hydroxytryptamine receptor 1B0213
Sodium-dependent serotonin transporter0202
D(3) dopamine receptor0303
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60202
Potassium channel subfamily K member 100101
Sodium-dependent dopamine transporter 0202
Potassium voltage-gated channel subfamily H member 20505
Cytochrome P450 1B10101
Nuclear receptor subfamily 3 group C member 3 0202
5-hydroxytryptamine receptor 2C0011
5-hydroxytryptamine receptor 2A0011
5-hydroxytryptamine receptor 1D0011
5-hydroxytryptamine receptor 1F0011
5-hydroxytryptamine receptor 2B0011
5-hydroxytryptamine receptor 60011
5-hydroxytryptamine receptor 7 0011
5-hydroxytryptamine receptor 5A0011
5-hydroxytryptamine receptor 5B0011
5-hydroxytryptamine receptor 3A0011
5-hydroxytryptamine receptor 4 0011
5-hydroxytryptamine receptor 3B0011
Chain A, Putative fructose-1,6-bisphosphate aldolase3003
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Estrogen-related receptor gamma0011
Chain A, Ferritin light chain3003
USP1 protein, partial6006
G5005
HLA class I histocompatibility antigen, B alpha chain 5005
Sarcoplasmic/endoplasmic reticulum calcium ATPase 10213
Inositol hexakisphosphate kinase 15005
cytochrome P450 2C9, partial5005
P531001
RPL19A0011
Histone H2A.x3003
Spike glycoprotein0011
Replicase polyprotein 1ab0011
NPC intracellular cholesterol transporter 1 precursor2002
nuclear factor erythroid 2-related factor 2 isoform 23003
nuclear factor NF-kappa-B p105 subunit isoform 11001
heat shock protein HSP 90-alpha isoform 20001
transactivating tegument protein VP16 [Human herpesvirus 1]0101
survival motor neuron protein isoform d3003
cytochrome P450 3A4 isoform 14004
COUP transcription factor 2 isoform a0101
Gamma-aminobutyric acid receptor subunit pi4329
Transmembrane protease serine 20011
Glucose transporter0101
Hexose transporter 1 0101
Procathepsin L0011
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Solute carrier family 2, facilitated glucose transporter member 10101
Gamma-aminobutyric acid receptor subunit beta-14329
Gamma-aminobutyric acid receptor subunit delta4329
Gamma-aminobutyric acid receptor subunit gamma-24329
Gamma-aminobutyric acid receptor subunit alpha-54329
Gamma-aminobutyric acid receptor subunit alpha-34329
Gamma-aminobutyric acid receptor subunit gamma-14329
Gamma-aminobutyric acid receptor subunit alpha-24329
Gamma-aminobutyric acid receptor subunit alpha-44329
Gamma-aminobutyric acid receptor subunit gamma-34329
Gamma-aminobutyric acid receptor subunit alpha-64329
Alpha-synuclein1001
Eukaryotic initiation factor 4A-I0101
Gamma-aminobutyric acid receptor subunit alpha-14329
Peptidyl-prolyl cis-trans isomerase FKBP1A0202
Gamma-aminobutyric acid receptor subunit beta-34329
Gamma-aminobutyric acid receptor subunit beta-24329
Peptidyl-prolyl cis-trans isomerase FKBP30101
Peptidyl-prolyl cis-trans isomerase FKBP40101
TAR DNA-binding protein 431001
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 10101
Hypoxia-inducible factor 1-alpha0101
GABA theta subunit4329
Endothelial PAS domain-containing protein 10101
Angiotensin-converting enzyme 2 0011
Gamma-aminobutyric acid receptor subunit epsilon4329
Peptidyl-prolyl cis-trans isomerase FKBP140101
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 40101
heat shock protein 90, putative0001
potassium voltage-gated channel subfamily H member 2 isoform d4004
exodeoxyribonuclease V subunit RecD0101
exodeoxyribonuclease V subunit RecB0101
exodeoxyribonuclease V subunit RecC0101
Gamma-aminobutyric acid 0101
Gamma-aminobutyric acid receptor subunit pi0202
Gamma-aminobutyric acid receptor subunit delta0202
Voltage-dependent L-type calcium channel subunit alpha-1F0101
Fatty acid-binding protein, liver0202
Alpha-1-acid glycoprotein 10001
Albumin0113
Albumin0011
Gamma-aminobutyric acid receptor subunit alpha-10203
Gamma-aminobutyric acid receptor subunit beta-10203
Gamma-aminobutyric acid receptor subunit alpha-20203
Gamma-aminobutyric acid receptor subunit alpha-30203
Gamma-aminobutyric acid receptor subunit alpha-10336
Translocator protein0113
Gamma-aminobutyric acid receptor subunit alpha-60101
Gamma-aminobutyric acid receptor subunit beta-10213
Gamma-aminobutyric acid receptor subunit gamma-20325
Gamma-aminobutyric acid receptor subunit alpha-40203
Gamma-aminobutyric acid receptor subunit gamma-20203
Gamma-aminobutyric acid receptor subunit gamma-20101
Gamma-aminobutyric acid receptor subunit delta0101
Gamma-aminobutyric acid receptor subunit alpha-20101
Gamma-aminobutyric acid receptor subunit alpha-30101
Gamma-aminobutyric acid receptor subunit gamma-30101
Gamma-aminobutyric acid receptor subunit beta-30325
Translocator protein0101
Translocator protein0202
Cholecystokinin receptor type A0101
Gastrin/cholecystokinin type B receptor0101
Gamma-aminobutyric acid receptor subunit alpha-50235
Gamma-aminobutyric acid receptor subunit alpha-30224
Gamma-aminobutyric acid receptor subunit alpha-20224
Gamma-aminobutyric acid receptor subunit beta-20224
Gamma-aminobutyric acid receptor subunit alpha-40213
Gamma-aminobutyric acid receptor subunit beta-10101
Gamma-aminobutyric acid receptor subunit alpha-10101
Gamma-aminobutyric acid receptor subunit beta-30101
Gamma-aminobutyric acid receptor subunit epsilon0202
Voltage-dependent L-type calcium channel subunit alpha-1D 0101
Neuronal acetylcholine receptor subunit alpha-70101
Voltage-dependent L-type calcium channel subunit alpha-1S0101
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Gamma-aminobutyric acid receptor subunit alpha-60213
Gamma-aminobutyric acid receptor subunit alpha-50101
Gamma-aminobutyric acid receptor subunit gamma-10202
Gamma-aminobutyric acid receptor subunit pi0101
Sphingosine-1-phosphate lyase 10101
Gamma-aminobutyric acid receptor subunit gamma-30202
Gamma-aminobutyric acid receptor subunit alpha-40101
Gamma-aminobutyric acid receptor subunit theta0101
Gamma-aminobutyric acid receptor subunit gamma-10101
Gamma-aminobutyric acid receptor subunit theta0202
Luciferase3003
Nuclear receptor subfamily 1 group I member 20011
D(4) dopamine receptor0101
Delta-type opioid receptor0202
Mu-type opioid receptor0314
Kappa-type opioid receptor0101
Histamine H1 receptor0101
Mu-type opioid receptor0213
Delta-type opioid receptor0303
Kappa-type opioid receptor0202
Kappa-type opioid receptor0202
Mu-type opioid receptor0101
Mu-type opioid receptor0202
Sigma non-opioid intracellular receptor 10303
Sigma non-opioid intracellular receptor 10202
Sigma non-opioid intracellular receptor 10101
Chain A, GLUTAMATE RECEPTOR SUBUNIT 20101
Chain A, Glutamate Receptor Subunit 20101
Chain B, Glutamate Receptor Subunit 20101
Chain A, Slr1257 protein0011
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]0101
beta-2 adrenergic receptor1001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 13003
Metabotropic glutamate receptor 80202
Metabotropic glutamate receptor 60113
Glutamate receptor ionotropic, NMDA 2D0101
Excitatory amino acid transporter 40101
Glutamate receptor ionotropic, NMDA 3B0101
Glutathione reductase, mitochondrial0202
Bifunctional aspartokinase/homoserine dehydrogenase 10101
Prothrombin0011
ATP-citrate synthase 0101
Glutamate receptor 10213
Glutamate receptor 30213
Glutamate receptor 40213
Glutamate receptor ionotropic, kainate 10213
Metabotropic glutamate receptor 10112
Metabotropic glutamate receptor 20011
Metabotropic glutamate receptor 30011
Metabotropic glutamate receptor 40112
Metabotropic glutamate receptor 50011
Metabotropic glutamate receptor 60011
Metabotropic glutamate receptor 70011
Glutamate receptor ionotropic, NMDA 1 0427
Glutamate receptor ionotropic, kainate 10112
Metabotropic glutamate receptor 50113
Glutamate receptor ionotropic, kainate 20213
Glutamate receptor 10213
Glutamate receptor 20213
Glutamate receptor 30112
Glutamate receptor ionotropic, kainate 30202
Excitatory amino acid transporter 10203
Excitatory amino acid transporter 20203
Excitatory amino acid transporter 30203
Metabotropic glutamate receptor 80011
Glutamate receptor 40213
Excitatory amino acid transporter 3 0001
Glutamate racemase0001
Metabotropic glutamate receptor 80112
Fatty-acid amide hydrolase 10202
Glutamate receptor ionotropic, NMDA 2A 0427
Glutamate receptor ionotropic, NMDA 2B0427
Glutamate receptor ionotropic, NMDA 2C0427
Glutamate receptor ionotropic, kainate 40202
Glutamate carboxypeptidase 20101
Glutamate receptor ionotropic, NMDA 10101
Glutamate receptor ionotropic, NMDA 2A0101
Glutamate receptor ionotropic, kainate 20112
Glutamate receptor ionotropic, kainate 30101
Glutamate receptor ionotropic, NMDA 2B0101
Metabotropic glutamate receptor 10113
Metabotropic glutamate receptor 20113
Metabotropic glutamate receptor 70113
Metabotropic glutamate receptor 30113
Metabotropic glutamate receptor 40113
Glutamate receptor ionotropic, NMDA 2C0101
Glutamate receptor ionotropic, kainate 50101
Carbonic anhydrase-like protein, putative0002
Glutamate receptor ionotropic, NMDA 2D0427
Glutamate receptor ionotropic, kainate 50202
Glutamate racemase0001
Prolyl 4-hydroxylase0101
Glutamate receptor ionotropic, NMDA 3A0101
Glutamate receptor ionotropic, NMDA 3B0427
Alpha-ketoglutarate-dependent dioxygenase FTO0101
Glutamate receptor ionotropic, NMDA 3A0427
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)3003
nonstructural protein 11001
cytochrome P450 2D61001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)3003
cytochrome P450 2D6 isoform 11001
cytochrome P450 2C9 precursor1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
Solute carrier family 22 member 60101
ATP-binding cassette sub-family C member 90101
Bile salt export pump0202
Chymotrypsinogen A0101
Beta-lactamase0101
ATP synthase subunit beta, mitochondrial0101
ATP synthase subunit delta, mitochondrial0101
ATP synthase subunit gamma, mitochondrial0101
ATP synthase subunit epsilon, mitochondrial0101
Cytochrome P450 2C9 0202
Cystic fibrosis transmembrane conductance regulator0101
Cholesteryl ester transfer protein0101
Peroxisome proliferator-activated receptor gamma0101
Malate dehydrogenase, cytoplasmic0101
Histamine H2 receptor2103
Solute carrier family 15 member 10101
Guanine nucleotide-binding protein G1001
Inositol monophosphatase 12002
ATP-binding cassette sub-family C member 80101
ATP-sensitive inward rectifier potassium channel 110101
Solute carrier family 22 member 70101
Solute carrier family 15 member 20101
NACHT, LRR and PYD domains-containing protein 3 0101
NACHT, LRR and PYD domains-containing protein 3 0101
CDGSH iron-sulfur domain-containing protein 10202
Glycine receptor subunit alpha-10011
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent glycine transporter 10101
Large neutral amino acids transporter small subunit 10303
Proton-coupled amino acid transporter 10202
Serine racemase0101
Olfactory receptor 51E20011
Sodium- and chloride-dependent glycine transporter 20101
Chain A, HADH2 protein2002
Chain B, HADH2 protein2002
Chain E, Fibrin beta chain0101
Chain A, JmjC domain-containing histone demethylation protein 3A1001
Chain A, ATP-DEPENDENT DNA HELICASE Q11001
Chain A, RNA-directed RNA polymerase NS50101
15-lipoxygenase, partial1001
WRN1001
Mcl-10101
MPI protein0101
Cyclin-dependent kinase 5, regulatory subunit 1 (p35)0001
alkaline phosphatase, intestinal0011
thioredoxin glutathione reductase2002
apical membrane antigen 1, AMA11001
hypothetical protein, conserved1001
glucocerebrosidase2002
luciferase1001
pyruvate kinase1001
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase0101
CDK50001
serine-protein kinase ATM isoform a1001
major prion protein preproprotein Prp precursor0101
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein0011
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 12002
glucose-6-phosphate 1-dehydrogenase isoform b0101
intestinal alkaline phosphatase precursor0011
serine/threonine-protein kinase PLK11001
DNA polymerase eta isoform 11001
lethal(3)malignant brain tumor-like protein 1 isoform I1001
Vif0101
Tat0101
DNA dC->dU-editing enzyme APOBEC-3G isoform 10101
alkaline phosphatase, germ cell type preproprotein0011
endoribonuclease toxin MazF0011
DNA dC->dU-editing enzyme APOBEC-3F isoform a1001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Rap guanine nucleotide exchange factor 31001
Pyruvate kinase PKM0101
Endothelin receptor type B1001
Endothelin-1 receptor1001
phosphoglycerate kinase1001
hypothetical protein CAALFM_CR05890CA0001
H3 histone acetyltransferase0001
large T antigen0101
acetylcholinesterase1001
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Chain B, Exotoxin A0011
Sodium channel protein type 1 subunit alpha0101
Sodium channel protein type 2 subunit alpha0101
Sodium channel protein type 3 subunit alpha0101
Vasopressin V2 receptor0112
Oxytocin receptor0224
Vasopressin V1a receptor0101
Vasopressin V1a receptor0213
Vasopressin V1b receptor0112
Vasopressin V1b receptor0101
Oxytocin receptor0101
Oxytocin receptor0011
Vasopressin V2 receptor 0101
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
Chain A, Ferritin light chain0011
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a2002
heat shock protein beta-11001
Fatty-acid amide hydrolase 10101
UDP-glucuronosyltransferase 1A90001
Polyunsaturated fatty acid lipoxygenase ALOX150101
Prostaglandin G/H synthase 10101
Sodium- and chloride-dependent GABA transporter 10101
Sodium- and chloride-dependent GABA transporter 20101
Sodium- and chloride-dependent GABA transporter 30101
Sodium- and chloride-dependent betaine transporter0101
UDP-glucuronosyltransferase 1A80001
Potassium channel subfamily K member 30101
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Chain A, Acetylcholinesterase0011
Acetylcholinesterase0101
DNA polymerase III, partial1001
atrial natriuretic peptide receptor 2 precursor1001
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 0101
Chain A, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)0101
Chain B, HDLP (HISTONE DEACETYLASE-LIKE PROTEIN)0101
Chain A, Histone deacetylase 7a0101
Chain A, Histone deacetylase 7a0101
Histone deacetylase 80101
Histone deacetylase 0101
Lysine-specific demethylase 4E0101
unnamed protein product0001
Histone deacetylase 10202
Histone deacetylase 30204
5-hydroxytryptamine receptor 3A0101
Histone deacetylase 30101
Plasma kallikrein0102
Cytochrome P450 1A20101
Coagulation factor VII0101
Leukotriene A-4 hydrolase0101
Cytochrome P450 2D60101
Vitamin D3 receptor0101
Tissue factor0101
Adenosine receptor A10101
Cytochrome P450 2C190101
Histone deacetylase 40216
Histone deacetylase 20101
Splicing factor 3B subunit 30101
Histone deacetylase 10101
Adenosine receptor A10101
Histone deacetylase 0101
Histone deacetylase 40101
Polyamine deacetylase HDAC100101
Histone deacetylase 30101
Histone deacetylase-like amidohydrolase0202
Histone deacetylase 70101
NAD-dependent protein deacetylase sirtuin-60112
Histone deacetylase 80101
Histone deacetylase 70204
Histone deacetylase 110101
HD2 type histone deacetylase HDA106 0202
Polyamine deacetylase HDAC100204
Histone deacetylase 11 0204
Histone deacetylase 90101
Histone deacetylase 70101
Histone deacetylase 6 0101
Histone deacetylase 40101
Histone deacetylase 80204
Histone deacetylase 90204
Histone deacetylase 50204
Histone deacetylase 0101
Nuclear receptor corepressor 20202
Histone deacetylase 60101
Histone deacetylase 50101
Histone deacetylase 0101
Chain A, Trp Rna-binding Attenuation Protein0011
Chain K, Trp Rna-binding Attenuation Protein0011
Chain B, tryptophanyl-tRNA synthetase0011
Chain C, Tryptophanyl-tRNA synthetase II0011
M-phase phosphoprotein 81001
Carbonic anhydrase 120001
Dihydrofolate reductase0202
Myeloperoxidase0101
Alkaline phosphatase, tissue-nonspecific isozyme0101
Carbonic anhydrase 30001
Stromelysin-10101
Intestinal-type alkaline phosphatase0101
Indoleamine 2,3-dioxygenase 10102
Carbonic anhydrase 40001
Carbonic anhydrase 60001
Substance-P receptor0101
Carbonic anhydrase 5A, mitochondrial0001
Carbonic anhydrase0001
Carbonic anhydrase 70001
Tryptophan 2,3-dioxygenase0102
Carbonic anhydrase0001
SLC16A10 protein0001
Uracil nucleotide/cysteinyl leukotriene receptor0101
Carbonic anhydrase 90001
Carbonic anhydrase 0001
Tryprostatin B synthase0001
Carbonic anhydrase0001
Carbonic anhydrase0001
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase0011
Carbonic anhydrase 0001
Monocarboxylate transporter 100001
Carbonic anhydrase 150001
Carbonic anhydrase 130001
Carbonic anhydrase 140001
Phospholipase A-2-activating protein0101
Carbonic anhydrase 5B, mitochondrial0001
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]