Page last updated: 2024-12-07

dibromobimane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

dibromobimane : A pyrazolopyrazole that consists of 1H,7H-pyrazolo[1,2-a]pyrazole-1,7-dione bearing two methyl substituents at positions 2 and 6 as well as two bromomethyl substituents at positions 3 and 5. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID125708
CHEMBL ID2158899
CHEBI ID62827
MeSH IDM0112477

Synonyms (24)

Synonym
nsc608550
9,methyl)bimane
nsc-608550
dibromobimane
dibromobimane, bioreagent, suitable for fluorescence, >=95.0% (chn)
1h,7h-pyrazolo(1,2-a)pyrazole-1,7-dione, 3,5-bis(bromomethyl)-2,6-dimethyl-
1,7-bis(bromomethyl)-2,6-dimethylpyrazolo[1,2-a]pyrazole-3,5-dione
68654-25-1
CHEMBL2158899
CHEBI:62827 ,
syn-(bromomethyl,methyl)bimane
3,5-bis(bromomethyl)-2,6-dimethyl-1h,7h-pyrazolo[1,2-a]pyrazole-1,7-dione
dbbr
bbbr
FT-0624667
EPITOPE ID:153548
DTXSID70218736
3,5-bis(bromomethyl)-2,6-dimethyl-1h,7h-[1,2]diazolo[1,2-a]pyrazole-1,7-dione
Q27132207
3-(3-carboxypropionylamino)phenylboronicacid
dbbr, bbbr
HY-D1423
CS-0374371
AS-76977

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (1)

RoleDescription
fluorochromeA fluorescent dye used to stain biological specimens.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
organobromine compoundA compound containing at least one carbon-bromine bond.
pyrazolopyrazoleAny organic heterobicyclic compound class containing two ortho-fused pyrazole rings.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID695527Induction of H2S production measured every 15 sec to 1 min by thiobimane fluorescent method2012Bioorganic & medicinal chemistry, Apr-15, Volume: 20, Issue:8
Thioglycine and L-thiovaline: biologically active H₂S-donors.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (28)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (21.43)18.7374
1990's4 (14.29)18.2507
2000's13 (46.43)29.6817
2010's3 (10.71)24.3611
2020's2 (7.14)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 20.47

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index20.47 (24.57)
Research Supply Index3.37 (2.92)
Research Growth Index4.54 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (20.47)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other28 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]