Assay ID | Title | Year | Journal | Article |
AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1254736 | Competitive inhibition of CYP2D6 (unknown origin) using dextromethorphan substrate | 2015 | Journal of medicinal chemistry, Nov-12, Volume: 58, Issue:21
| Development of Safe and Effective Botanical Dietary Supplements. |
AID400864 | Spasmolytic activity in isolated guinea pig ileum assessed as spasmogen-induced inhibition of smooth muscle contraction | | | |
AID380503 | Displacement of [3H]8-OH-DPAT from human recombinant 5HT1A receptor expressed in CHO cells | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3
| Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. |
AID400829 | Spasmolytic activity against guinea pig ileum assessed as inhibition of spasmogen-induced contraction at 10 ug | | | |
AID378591 | Antiplasmodial activity against multi drug-resistant Plasmodium falciparum K1 in erythrocytes by [3H]hypoxanthine uptake | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12
| In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids. |
AID334627 | Inhibition of acetylcholine-induced contraction in guinea pig ileum preincubated for 10 mins before acetylcholine challenge | | | |
AID380506 | Inhibition of CYP3A4 | 2006 | Journal of natural products, Mar, Volume: 69, Issue:3
| Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. |
AID400831 | Spasmolytic activity against guinea pig ileum assessed as inhibition of spasmogen-induced contraction | | | |
AID334628 | Inhibition of acetylcholine-induced contraction in guinea pig ileum preincubated for 20 mins before acetylcholine challenge | | | |
AID400830 | Spasmolytic activity against guinea pig ileum assessed as inhibition of spasmogen-induced contraction at 50 ug | | | |
AID493705 | Cytotoxicity against human A549 cells by SRB assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Benzylisoquinoline alkaloids from the tubers of Corydalis ternata and their cytotoxicity. |
AID334629 | Inhibition of histamine-induced contraction in guinea pig ileum | | | |
AID378593 | Cytotoxicity against human KB cells after 72 hrs | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12
| In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids. |
AID378592 | Antiamnesic activity against Entamoeba histolytica NIH 200 after 72 hrs by microdilution technique | 2000 | Journal of natural products, Dec, Volume: 63, Issue:12
| In vitro antiplasmodial, antiamoebic, and cytotoxic activities of some monomeric isoquinoline alkaloids. |
AID493706 | Cytotoxicity against human SKOV3 cells by SRB assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Benzylisoquinoline alkaloids from the tubers of Corydalis ternata and their cytotoxicity. |
AID493707 | Cytotoxicity against human SK-MEL-2 cells by SRB assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Benzylisoquinoline alkaloids from the tubers of Corydalis ternata and their cytotoxicity. |
AID400863 | Spasmolytic activity in isolated guinea pig ileum assessed as spasmogen-induced inhibition of smooth muscle contraction at 10 ug | | | |
AID493708 | Cytotoxicity against human HCT15 cells by SRB assay | 2010 | Bioorganic & medicinal chemistry letters, Aug-01, Volume: 20, Issue:15
| Benzylisoquinoline alkaloids from the tubers of Corydalis ternata and their cytotoxicity. |
AID400862 | Spasmolytic activity in isolated guinea pig ileum assessed as spasmogen-induced inhibition of smooth muscle contraction at 10 ug | | | |
AID632313 | Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by griess assay | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23
| Alkaloids from Chelidonium majus and their inhibitory effects on LPS-induced NO production in RAW264.7 cells. |
AID632314 | Cytotoxicity against mouse RAW264.7 cells assessed as cell viability at 50 uM after 24 hrs by MTT assay | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23
| Alkaloids from Chelidonium majus and their inhibitory effects on LPS-induced NO production in RAW264.7 cells. |
AID377193 | Antimicrobial activity against Staphylococcus aureus 4222 with norA KLE 820(3) mutation | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8
| 5'-Methoxyhydnocarpin-D and pheophorbide A: Berberis species components that potentiate berberine growth inhibition of resistant Staphylococcus aureus. |
AID334626 | Inhibition of acetylcholine-induced contraction in guinea pig ileum preincubated for 5 mins before acetylcholine challenge | | | |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |