Page last updated: 2024-11-05

diphenylcarbazide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Diphenylcarbazide is a colorless, crystalline compound with the chemical formula (C6H5NHNH)2CO. It is used as a reagent for the detection of chromium(VI) ions. In acidic solutions, it forms a violet-colored complex with chromium(VI), which can be used for spectrophotometric analysis. Diphenylcarbazide is also used as a catalyst for the oxidation of alcohols, and as a reagent in the synthesis of various organic compounds. Its synthesis typically involves the reaction of phenylhydrazine with urea. Diphenylcarbazide is studied due to its ability to detect and quantify chromium, which is an important element in various industrial processes. It is also used in research to understand the mechanisms of oxidation and catalysis.'

Diphenylcarbazide: Used as an indicator in titrating iron and for the colorimetric determination of chromium and the detection of cadmium, mercury, magnesium, aldehydes, and emetine. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID8789
CHEBI ID4641
SCHEMBL ID294587
MeSH IDM0006516

Synonyms (61)

Synonym
HMS1578M04
CBDIVE_014231
1,5-diphenylcarbohydrazide
sym-diphenylcarbazide
1,5-diphenylcabohydrazide
nsc5058
1,5-diphenylcarbazide
carbohydrazide,5-diphenyl-
1,5-diphenylcarbohydrazine
diphenyl carbazide
nsc-5058
carbonic dihydrazide,2'-diphenyl-
2,2'-diphenylcarbonic dihydrazide
2,2'-diphenylcarbazide
1,5-diphenylcarbonohydrazide
2,5-diphenylcarbazide
brn 0752039
ai3-00869
n,n'-diphenylcarbazide
nsc 5058
einecs 205-403-7
carbonic dihydrazide, 2,2'-diphenyl-
carbohydrazide, 1,5-diphenyl-
140-22-7
diphenylcarbazide
1,5-diphenylcarbazide, acs reagent
1,5-diphenylcarbazide, reagent grade
1,3-dianilinourea
D1513
AKOS000120184
amino-(hydrazinecarbonyl)-diphenyl-ammonium;1,5-diphenylcarbohydrazide
A807630
n'',n'''-diphenylcarbonohydrazide
STL283945
unii-1w1xpa8n0p
4-15-00-00182 (beilstein handbook reference)
1w1xpa8n0p ,
FT-0625228
s-diphenylcarbazide
sym-diphenylcarbazide [mi]
SCHEMBL294587
DTXSID7059690
CHEBI:4641
W-108208
n',n''-diphenylcarbonohydrazide #
s-diphenyl carbazide
mfcd00003013
1,5-diphenylcarbazide, reag. ph. eur., >=98.0%, for metal titration
1,5-diphenylcarbazide, jis special grade
SR-01000196298-1
sr-01000196298
1,5-diphenylcarbazide, p.a., acs reagent, reag. ph. eur.
diphenylcarbazid
AS-13073
Q1227137
SY010365
1,5-diphenylcarbohydrazid
4-(4-amino-3-(4-amino-3-fluorophenoxy)phenoxy)-n-methylpicolinamide hydrochloride
1,5-diphenylcarbazide, acs grade
CS-W012774
EN300-19423

Research Excerpts

Overview

Diphenylcarbazide (DPC) is an efficient electron donor to the inactive oxygen-evolving complex of photosystem II.

ExcerptReferenceRelevance
"Diphenylcarbazide (DPC) is an efficient electron donor to the inactive oxygen-evolving complex of photosystem II (PSII). "( Electron donation to photosystem II by diphenylcarbazide is inhibited both by the endogenous manganese complex and by exogenous manganese ions.
Popovic, R; Rashid, A,
)
1.84
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
phenylhydrazinesAny member of the class of hydrazines carrying a phenyl substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (77)

TimeframeStudies, This Drug (%)All Drugs %
pre-199024 (31.17)18.7374
1990's11 (14.29)18.2507
2000's13 (16.88)29.6817
2010's27 (35.06)24.3611
2020's2 (2.60)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 50.69

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index50.69 (24.57)
Research Supply Index4.44 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index79.23 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (50.69)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other84 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]