Compounds > diphenylcarbazide
Page last updated: 2024-09-21

diphenylcarbazide

Description

Diphenylcarbazide: Used as an indicator in titrating iron and for the colorimetric determination of chromium and the detection of cadmium, mercury, magnesium, aldehydes, and emetine. [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID8789
CHEBI ID4641
SCHEMBL ID294587
MeSH IDM0006516

Synonyms (61)

Synonym
HMS1578M04
CBDIVE_014231
1,5-diphenylcarbohydrazide
sym-diphenylcarbazide
1,5-diphenylcabohydrazide
nsc5058
1,5-diphenylcarbazide
carbohydrazide,5-diphenyl-
1,5-diphenylcarbohydrazine
diphenyl carbazide
nsc-5058
carbonic dihydrazide,2'-diphenyl-
2,2'-diphenylcarbonic dihydrazide
2,2'-diphenylcarbazide
1,5-diphenylcarbonohydrazide
2,5-diphenylcarbazide
brn 0752039
ai3-00869
n,n'-diphenylcarbazide
nsc 5058
einecs 205-403-7
carbonic dihydrazide, 2,2'-diphenyl-
carbohydrazide, 1,5-diphenyl-
140-22-7
diphenylcarbazide
1,5-diphenylcarbazide, acs reagent
1,5-diphenylcarbazide, reagent grade
1,3-dianilinourea
D1513
AKOS000120184
amino-(hydrazinecarbonyl)-diphenyl-ammonium;1,5-diphenylcarbohydrazide
A807630
n'',n'''-diphenylcarbonohydrazide
STL283945
unii-1w1xpa8n0p
4-15-00-00182 (beilstein handbook reference)
1w1xpa8n0p ,
FT-0625228
s-diphenylcarbazide
sym-diphenylcarbazide [mi]
SCHEMBL294587
DTXSID7059690
CHEBI:4641
W-108208
n',n''-diphenylcarbonohydrazide #
s-diphenyl carbazide
mfcd00003013
1,5-diphenylcarbazide, reag. ph. eur., >=98.0%, for metal titration
1,5-diphenylcarbazide, jis special grade
SR-01000196298-1
sr-01000196298
1,5-diphenylcarbazide, p.a., acs reagent, reag. ph. eur.
diphenylcarbazid
AS-13073
Q1227137
SY010365
1,5-diphenylcarbohydrazid
4-(4-amino-3-(4-amino-3-fluorophenoxy)phenoxy)-n-methylpicolinamide hydrochloride
1,5-diphenylcarbazide, acs grade
CS-W012774
EN300-19423

Drug Classes (1)

ClassDescription
phenylhydrazinesAny member of the class of hydrazines carrying a phenyl substituent.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID588519A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities2011Antiviral research, Sep, Volume: 91, Issue:3
High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors.
AID540299A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis2010Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (77)

TimeframeStudies, This Drug (%)All Drugs %
pre-199024 (31.17)18.7374
1990's11 (14.29)18.2507
2000's13 (16.88)29.6817
2010's27 (35.06)24.3611
2020's2 (2.60)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other84 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
chromium[no description available]medium140chromium cation;
monoatomic hexacation
chromium[no description available]medium390chromium group element atom;
metal allergen		micronutrient
ethylene dimethacrylate[no description available]medium10enoate esterallergen;
cross-linking reagent;
polymerisation monomer
nickel[no description available]medium30metal allergen;
nickel group element atom		epitope;
micronutrient
cadmium[no description available]medium40cadmium molecular entity;
zinc group element atom
aluminum oxide[no description available]medium10
chitosan[no description available]medium10
sodium dodecyl sulfate[no description available]medium10organic sodium saltdetergent;
protein denaturant
diphenylcarbazone[no description available]medium30
silver[no description available]medium10copper group element atom;
elemental silver		Escherichia coli metabolite
methane[no description available]medium10alkane;
gas molecular entity;
mononuclear parent hydride;
one-carbon compound		bacterial metabolite;
fossil fuel;
greenhouse gas
cerium[no description available]medium20f-block element atom;
lanthanoid atom
nitric acid[no description available]medium20nitrogen oxoacidprotic solvent;
reagent
manganese[no description available]medium100elemental manganese;
manganese group element atom		Escherichia coli metabolite;
micronutrient
asparagine[no description available]medium10amino acid zwitterion;
asparagine;
aspartate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
plant metabolite;
Saccharomyces cerevisiae metabolite
2,6-dichloroindophenol[no description available]medium150dichlorobenzene;
quinone imine
chlorophyll a[no description available]medium70chlorophyll;
methyl ester		cofactor
hydroxyl radical[no description available]medium10oxygen hydride;
oxygen radical;
reactive oxygen species
titanium[no description available]medium20titanium group element atom
titanium dioxide[no description available]medium20titanium oxidesfood colouring
mannitol[no description available]medium10mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
ascorbic acid[no description available]medium10ascorbic acid;
vitamin C		coenzyme;
cofactor;
flour treatment agent;
food antioxidant;
food colour retention agent;
geroprotector;
plant metabolite;
skin lightening agent
chromates[no description available]medium20chromium oxoanion;
divalent inorganic anion		oxidising agent
nitrites[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species		human metabolite
tyrosine[no description available]medium20amino acid zwitterion;
erythrose 4-phosphate/phosphoenolpyruvate family amino acid;
L-alpha-amino acid;
proteinogenic amino acid;
tyrosine		EC 1.3.1.43 (arogenate dehydrogenase) inhibitor;
fundamental metabolite;
micronutrient;
nutraceutical
hydroxylamine[no description available]medium10hydroxylaminesalgal metabolite;
bacterial xenobiotic metabolite;
EC 1.1.3.13 (alcohol oxidase) inhibitor;
EC 4.2.1.22 (cystathionine beta-synthase) inhibitor;
EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor;
nitric oxide donor;
nucleophilic reagent
ceric oxide[no description available]medium10cerium molecular entity;
metal oxide
zeolites[no description available]medium10
chlorine[no description available]medium10diatomic chlorine;
gas molecular entity		bleaching agent
carbon tetrachloride[no description available]medium10chlorocarbon;
chloromethanes		hepatotoxic agent;
refrigerant
beta carotene[no description available]medium10carotenoid beta-end derivative;
cyclic carotene		antioxidant;
biological pigment;
cofactor;
ferroptosis inhibitor;
human metabolite;
mouse metabolite;
plant metabolite;
provitamin A
betaine[no description available]medium10amino-acid betaine;
glycine derivative		fundamental metabolite
thallium[no description available]medium10boron group element atom
edetic acid[no description available]medium10ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
benzanilide[no description available]medium10
sulfuric acid[no description available]medium10sulfur oxoacidcatalyst
chlorpromazine[no description available]medium10organochlorine compound;
phenothiazines;
tertiary amine		anticoronaviral agent;
antiemetic;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
phenothiazine antipsychotic drug
chromic acid[no description available]medium10chromium oxoacidoxidising agent
carbonates[no description available]medium20carbon oxoanion
tocopherylquinone[no description available]medium10
1,1-diphenyl-2-picrylhydrazyl[no description available]medium10
hydrazine[no description available]medium10azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
d-alpha tocopherol[no description available]medium10alpha-tocopherolalgal metabolite;
antiatherogenic agent;
anticoagulant;
antioxidant;
antiviral agent;
EC 2.7.11.13 (protein kinase C) inhibitor;
immunomodulator;
micronutrient;
nutraceutical;
plant metabolite
cobalt[no description available]medium10cobalt group element atom;
metal allergen		micronutrient
ethylene glycol[no description available]medium10ethanediol;
glycol		metabolite;
mouse metabolite;
solvent;
toxin
ethyldimethylaminopropyl carbodiimide[no description available]medium10
diuron[no description available]medium303-(3,4-substituted-phenyl)-1,1-dimethylurea;
dichlorobenzene		environmental contaminant;
mitochondrial respiratory-chain inhibitor;
photosystem-II inhibitor;
urea herbicide;
xenobiotic
aspartic acid[no description available]medium10aspartate family amino acid;
aspartic acid;
L-alpha-amino acid;
proteinogenic amino acid		Escherichia coli metabolite;
mouse metabolite;
neurotransmitter
platinum tetrachloride[no description available]medium10platinum coordination entitycatalyst;
reagent
cysteine[no description available]medium10cysteiniumfundamental metabolite
histidine[no description available]medium10amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
tromethamine[no description available]medium20primary amino compound;
triol		buffer
potassium persulfate[no description available]medium10
tannins[no description available]medium10
sodium perchlorate[no description available]medium10inorganic sodium salt
paraquat[no description available]medium10organic cationgeroprotector;
herbicide
digitonin[no description available]medium20
nadp[no description available]medium10
dibromothymoquinone[no description available]medium101,4-benzoquinonescytochrome-b6f complex inhibitor
glutaral[no description available]medium10dialdehydecross-linking reagent;
disinfectant;
fixative
1,7-phenanthroline[no description available]medium20phenanthroline
gramicidin a[no description available]medium10
dicyclohexylcarbodiimide[no description available]medium10carbodiimideATP synthase inhibitor;
cross-linking reagent;
peptide coupling reagent
valinomycin[no description available]medium10cyclodepsipeptide;
macrocycle		antimicrobial agent;
antiviral agent;
bacterial metabolite;
potassium ionophore
carbonyl cyanide m-chlorophenyl hydrazone[no description available]medium10hydrazone;
monochlorobenzenes;
nitrile		antibacterial agent;
geroprotector;
ionophore
phencyclidine[no description available]medium10benzenes;
piperidines		anaesthetic;
neurotoxin;
NMDA receptor antagonist;
psychotropic drug
hydrogen carbonate[no description available]medium10carbon oxoanioncofactor;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
hexacyanoferrate iii[no description available]medium10
catechol[no description available]medium10catecholsallelochemical;
genotoxin;
plant metabolite
hydrogen[no description available]medium10elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
duroquinol[no description available]medium10hydroquinones;
methylbenzene		bacterial xenobiotic metabolite;
volatile oil component
pheophytin a[no description available]medium10
1-(2-pyridylazo)-2-naphthol[no description available]medium10
aluminum[no description available]medium10boron group element atom;
elemental aluminium;
metal atom
1,10-phenanthroline[no description available]medium10phenanthrolineEC 2.7.1.1 (hexokinase) inhibitor;
EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor
chrome azurol s[no description available]medium10
2-naphthol[no description available]medium10naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
phenylglyoxal[no description available]medium10phenylacetaldehydes
chromium nitrate[no description available]medium10chromium coordination entity;
inorganic nitrate salt
potassium dichromate[no description available]medium10potassium saltallergen;
oxidising agent;
sensitiser
nitrates[no description available]medium10monovalent inorganic anion;
nitrogen oxoanion;
reactive nitrogen species
acetylacetone[no description available]medium10beta-diketone
diacetyl[no description available]medium10alpha-diketoneEscherichia coli metabolite;
Saccharomyces cerevisiae metabolite
formaldehyde[no description available]medium10aldehyde;
one-carbon compound		allergen;
carcinogenic agent;
disinfectant;
EC 3.5.1.4 (amidase) inhibitor;
environmental contaminant;
Escherichia coli metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
n-nitrosodiphenylamine[no description available]low00phenylhydrazines
phenylhydrazine[no description available]low00phenylhydrazinesxenobiotic
cryogenine[no description available]low00phenylhydrazines
(2-methylanilino)thiourea[no description available]low00phenylhydrazines
7-methyl-3-(phenylhydrazo)-1,5-benzodiazepin-2-one[no description available]low00phenylhydrazines
1-anilino-3-ethylthiourea[no description available]low00phenylhydrazines
N'-(3-chloro-4-methylphenyl)-5-isoxazolecarbohydrazide[no description available]low00phenylhydrazines
N'-(4-chloro-2-methylphenyl)-4-methyl-5-thiadiazolecarbohydrazide[no description available]low00phenylhydrazines
N'-(3-methylphenyl)cyclobutanecarbohydrazide[no description available]low00phenylhydrazines
(4-chloro-2-methylanilino)thiourea[no description available]low00phenylhydrazines
4-nitrophenylhydrazine[no description available]low00C-nitro compound;
phenylhydrazines		mutagen
2,4-dinitrophenylhydrazine[no description available]low00C-nitro compound;
phenylhydrazines		reagent
2-hydroxy-2-pentyl-N'-phenylheptanehydrazide[no description available]low00phenylhydrazines
(2,5-dimethylanilino)thiourea[no description available]low00phenylhydrazines
1-(2-fluorophenyl)-3-(N-(phenylmethyl)anilino)thiourea[no description available]low00phenylhydrazines
ConditionIndicatedRelationship StrengthStudiesTrials
Allergic Contact Dermatitis0low10
Allergic Reaction0low10
Allergy0low10
Coronary Disease0low10
Coronary Heart Disease0low10
Dermatitis, Allergic Contact0low10
Dermatitis, Allergic Eczematous0low10
Dermatitis, Contact, Allergic0low10
Diseases, Occupational0low10
Encephalitis, Polio0low10
Epidemic Acute Poliomyelitis0low10
Hypersensitivity0low10
Infantile Paralysis0low10
Occupational Diseases0low10
Occupational Illnesses0low10
Polio0low10
Polio Encephalitis0low10
Poliomyelitis0low10
Poliomyelitis Infection0low10
Poliomyelitis, Acute0low10
Poliomyelitis, Nonpoliovirus0low10
Poliomyelitis, Preparalytic0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
Evaluation of bacterial biosensors to determine chromate bioavailability and to assess ecotoxicity of soils.
Chemosphere, Volume: 128		2015
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (1)

ArticleYear
Evaluation of bacterial biosensors to determine chromate bioavailability and to assess ecotoxicity of soils.
Chemosphere, Volume: 128		2015
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]