Page last updated: 2024-08-23

dianhydrogalactitol and mitolactol

dianhydrogalactitol has been researched along with mitolactol in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199012 (92.31)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Olah, E; Palyi, I; Sugar, J1
Institoris, L; Jeney, A; Szende, B1
Andersen, J; Frei, E; Furlong, EA; Henner, WD; Kelley, SL; Peters, WP1
Csetényi, J; Eckhardt, S; Hegedüs, L; Horváth, IP; Kanyár, B; Kerpel-Fronius, S1
Eckhardt, S; Horváth, IP; Institoris, L; Kerpel-Fronius, S1
Kerpel-Fronius, S1
Edwards, MS; Fulton, D; Gutin, PH; Levin, VA; Seager, M; Vestnys, P; Wilson, CB1
Chiuten, DF; Muggia, FM; Rozencweig, M; Von Hoff, DD1
Hegedüs, L; Horváth, IP; Jarman, M; Somfai-Relle, S1
Hedegüs, L; Somfai-Relle, S; Sugár, J; Tóth, K1
Levin, VA; Wheeler, KT1
Gáti, E; Somfai-Relle, S1
Gáti, E; Holczinger, L; Institoris, E; Somfai-Relle, S; Turi, G1

Reviews

2 review(s) available for dianhydrogalactitol and mitolactol

ArticleYear
Hungarian anticancer drugs (antineoplastics).
    Therapia Hungarica (English edition), 1982, Volume: 30, Issue:3

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Dianhydrogalactitol; Erythritol; Humans; Kinetics; Mannomustine; Mesylates; Mitobronitol; Mitolactol; Rats

1982
Clinical trials with the hexitol derivatives in the U.S.
    Cancer, 1981, Feb-01, Volume: 47, Issue:3

    Topics: Animals; Clinical Trials as Topic; Dianhydrogalactitol; Dogs; Humans; Kinetics; Mannitol; Mice; Mitobronitol; Mitolactol; Neoplasms; Sugar Alcohols

1981

Trials

1 trial(s) available for dianhydrogalactitol and mitolactol

ArticleYear
Clinical trials with the hexitol derivatives in the U.S.
    Cancer, 1981, Feb-01, Volume: 47, Issue:3

    Topics: Animals; Clinical Trials as Topic; Dianhydrogalactitol; Dogs; Humans; Kinetics; Mannitol; Mice; Mitobronitol; Mitolactol; Neoplasms; Sugar Alcohols

1981

Other Studies

11 other study(ies) available for dianhydrogalactitol and mitolactol

ArticleYear
Effects of cytostatics on proliferating and stationary cultures of mammalian cells.
    European journal of cancer, 1978, Volume: 14, Issue:8

    Topics: Antineoplastic Agents; Bleomycin; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Dianhydrogalactitol; Dose-Response Relationship, Drug; Mitolactol; Vinca Alkaloids; Vincristine

1978
The diverse modification of N-butyl-N-(4-hydroxybutyl) nitrosamine induced carcinogenesis in urinary bladder by dibromodulcitol and dianhydrodulcitol.
    Acta morphologica Hungarica, 1992, Volume: 40, Issue:1-4

    Topics: Administration, Intravesical; Administration, Oral; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Dianhydrogalactitol; Doxorubicin; Female; Mitolactol; Papilloma; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms

1992
Pharmacokinetics of dibromodulcitol in humans: a phase I study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1986, Volume: 4, Issue:5

    Topics: Absorption; Administration, Oral; Adult; Aged; Bone Marrow Transplantation; Carcinoma; Dianhydrogalactitol; Dose-Response Relationship, Drug; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Melanoma; Middle Aged; Mitolactol; Neoplasm Metastasis; Sarcoma; Time Factors

1986
Pharmacokinetics and metabolism of dianhydrogalactitol DAG in patients: a comparison with the human disposition of dibromodulcitol DBD.
    European journal of cancer & clinical oncology, 1986, Volume: 22, Issue:2

    Topics: Adult; Aged; Alkylation; Biotransformation; Dianhydrogalactitol; Female; Humans; Kinetics; Male; Middle Aged; Mitolactol; Models, Biological; Neoplasms; Pleural Effusion; Protein Binding; Sugar Alcohols

1986
Phase I and II studies of cytostatic hexitol derivatives: the role of alkylating metabolites?
    Gan to kagaku ryoho. Cancer & chemotherapy, 1985, Volume: 12, Issue:3 Pt 2

    Topics: Animals; Antineoplastic Agents; Chemical Phenomena; Chemistry; Dianhydrogalactitol; DNA Replication; Drug Evaluation; Female; Humans; Male; Mice; Mitolactol; Neoplasms; Neoplasms, Experimental; Structure-Activity Relationship; Sugar Alcohols

1985
Phase II evaluation of dibromodulcitol in the treatment of recurrent medulloblastoma, ependymoma, and malignant astrocytoma.
    Journal of neurosurgery, 1984, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Brain Neoplasms; Child; Child, Preschool; Dianhydrogalactitol; Drug Evaluation; Ependymoma; Female; Glioma; Humans; Male; Medulloblastoma; Middle Aged; Mitolactol; Neoplasm Recurrence, Local

1984
Toxicity, antitumour and haematological effects of 1,2-anhydro-6-bromogalactitol and d-mannitol: a comparison with the related dibromo- and dianhydro-derivatives.
    European journal of cancer & clinical oncology, 1982, Volume: 18, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma 256, Walker; Dianhydrogalactitol; Lethal Dose 50; Leukopenia; Mannitol; Mice; Mitobronitol; Mitolactol; Rats

1982
Mutagenicity of dibromodulcitol (DBD), an alkylating anticancer drug) and its mono- and bifunctional conversion products studied by the Salmonella/microsome assay.
    Carcinogenesis, 1982, Volume: 3, Issue:3

    Topics: Animals; Carcinogens; Cyclophosphamide; Dianhydrogalactitol; Dose-Response Relationship, Drug; Liver; Male; Mitolactol; Mutagenicity Tests; Mutation; Rats; Rats, Inbred Strains; Salmonella typhimurium

1982
Chemotherapeutic approaches to brain tumors. Experimental observations with dianhydrogalactitol and dibromodulcitol.
    Cancer chemotherapy and pharmacology, 1982, Volume: 8, Issue:1

    Topics: Animals; Brain Neoplasms; Carmustine; Cells, Cultured; Dianhydrogalactitol; Drug Therapy, Combination; Humans; Kinetics; Mice; Mice, Inbred C57BL; Mitolactol; Neoplasms, Experimental; Rats; Rats, Inbred F344; Sugar Alcohols

1982
Effect of phenobarbital on the toxicity and antitumor activity of dibromodulcitol and dianhydrogalactitol.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:2

    Topics: Animals; Antineoplastic Agents; Dianhydrogalactitol; Drug Interactions; Female; Mice; Mitolactol; Phenobarbital; Rats; Rats, Inbred Strains; Sugar Alcohols

1982
Complex evaluation of the effect of some cytostatic hexitol derivatives.
    Oncology, 1980, Volume: 37 Suppl 1

    Topics: Animals; Antineoplastic Agents; Dianhydrogalactitol; Drug Evaluation, Preclinical; Mice; Mitolactol; Neoplasms, Experimental; Sugar Alcohols

1980