Compounds > 4-acetylpyridine
Page last updated: 2024-09-21

4-acetylpyridine

Cross-References

ID SourceID
PubMed CID14282
CHEMBL ID445953
SCHEMBL ID55235
MeSH IDM0156342

Synonyms (56)

Synonym
5-21-07-00400 (beilstein handbook reference)
g47437iow7 ,
unii-g47437iow7
4-acetyl pyridine
1-pyridin-4-ylethanone
pyridine,4-acetyl
inchi=1/c7h7no/c1-6(9)7-2-4-8-5-3-7/h2-5h,1h
nsc 111
brn 0107629
ai3-26822
einecs 214-350-9
ccris 5954
pyridine, 4-acetyl-
methyl 4-pyridyl ketone
1122-54-9
4-acetylpyridine
nsc-111
ethanone, 1-(4-pyridinyl)-
wln: t6nj dv1
nsc111
ketone, methyl 4-pyridyl
4-pyridyl methyl ketone
4-acetylpyridine, 97%
A0113 ,
methyl 4-pyridylketone
CHEMBL445953
AKOS000119796
1-(4-pyridyl)ethanone;4-acetylpyridine
A802523
FT-0617410
AM20050673
AB00760
SCHEMBL55235
4-acetyl-pyridine
1-(4-pyridyl)ethanone
1-pyridin-4-yl-ethanone
1-(pyridin-4-yl)-ethanone
1-(pyridin-4-yl)ethanone
1-(pyridin-4-yl)ethan-1-one
FG-0441
acetyl pyridine, 4-
1-(4-pyridinyl)ethanone
1-(4-pyridinyl)ethanone #
.gamma.-acetylpyridine
Q-100066
DTXSID0022147
mfcd00006433
CS-W008727
F0001-0269
AC-8358
4-acetylpyridine, vetec(tm) reagent grade, 97%
SY005519
EN300-17993
STL185607
Q27278737
HY-Y0179

Bioassays (6)

Assay IDTitleYearJournalArticle
AID1090712Thrips luring activity against male New Zealand Thrips obscuratus (flower thrips) assessed as ratio of thrips in baited traps to unbaited traps during field trapping study2007Journal of agricultural and food chemistry, Jul-25, Volume: 55, Issue:15
4-pyridyl carbonyl and related compounds as thrips lures: effectiveness for onion thrips and new zealand flower thrips in field experiments.
AID1090711Thrips luring activity against female Thrips tabaci (onion thrips) assessed as ratio of thrips in baited traps to unbaited traps during field trapping study2007Journal of agricultural and food chemistry, Jul-25, Volume: 55, Issue:15
4-pyridyl carbonyl and related compounds as thrips lures: effectiveness for onion thrips and new zealand flower thrips in field experiments.
AID1091222Thrips luring activity against female Frankliniella occidentalis (western flower thrips) assessed as trapping of thrips using compound treated yellow sticky traps relative to untreated control under commercial greenhouse2008Journal of agricultural and food chemistry, Aug-13, Volume: 56, Issue:15
4-Pyridyl carbonyl compounds as thrips lures: effectiveness for Western flower thrips in y-tube bioassays.
AID343684Alkane-water partition coefficient, log P of the compound2008Journal of medicinal chemistry, Jul-10, Volume: 51, Issue:13
Toward prediction of alkane/water partition coefficients.
AID1090713Thrips luring activity against female New Zealand Thrips obscuratus (flower thrips) assessed as ratio of thrips in baited traps to unbaited traps during field trapping study2007Journal of agricultural and food chemistry, Jul-25, Volume: 55, Issue:15
4-pyridyl carbonyl and related compounds as thrips lures: effectiveness for onion thrips and new zealand flower thrips in field experiments.
AID343683Octanol-water partition coefficient, log P of the compound2008Journal of medicinal chemistry, Jul-10, Volume: 51, Issue:13
Toward prediction of alkane/water partition coefficients.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (17)

TimeframeStudies, This Drug (%)All Drugs %
pre-19903 (17.65)18.7374
1990's3 (17.65)18.2507
2000's8 (47.06)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other17 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceDescriptionRelationhip StrengthStudiesTrialsClassesRoles
benzaldehyde[no description available]medium10benzaldehydesEC 3.1.1.3 (triacylglycerol lipase) inhibitor;
EC 3.5.5.1 (nitrilase) inhibitor;
flavouring agent;
fragrance;
odorant receptor agonist;
plant metabolite
methyl salicylate[no description available]medium10benzoate ester;
methyl ester;
salicylates		flavouring agent;
insect attractant;
metabolite
phenylethyl alcohol[no description available]medium10benzenes;
primary alcohol		Aspergillus metabolite;
fragrance;
plant growth retardant;
plant metabolite;
Saccharomyces cerevisiae metabolite
chloroform[no description available]medium10chloromethanes;
one-carbon compound		carcinogenic agent;
central nervous system drug;
inhalation anaesthetic;
non-polar solvent;
refrigerant
Ethyl 2-aminobenzoate[no description available]medium10benzoate ester
salicylaldehyde[no description available]medium10hydroxybenzaldehydenematicide;
plant metabolite
methyl benzoate[no description available]medium10benzoate ester;
methyl ester		insect attractant;
metabolite
ethyl benzoate[no description available]medium10benzoate ester;
ethyl ester		flavouring agent;
fragrance;
volatile oil component
4-cyanopyridine[no description available]medium30
ethyl salicylate[no description available]medium10hydroxybenzoic acid
methyl anthranilate[no description available]medium10benzoate esterflavouring agent;
metabolite
ethyl isonicotinate[no description available]medium20
4-anisaldehyde[no description available]medium20benzaldehydesbacterial metabolite;
human urinary metabolite;
insect repellent;
plant metabolite
ethylnicotinate[no description available]medium20aromatic carboxylic acid;
pyridines
beta-ionone[no description available]medium10iononeantioxidant;
fragrance
Jasmone[no description available]medium10cyclic ketone
alpha-ionone[no description available]medium10enone;
ionone;
methyl ketone
MeJA[no description available]medium10Jasmonate derivatives
acetone[no description available]medium10ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
coumarin[no description available]medium10coumarinsfluorescent dye;
human metabolite;
plant metabolite
indole[no description available]medium10indole;
polycyclic heteroarene		Escherichia coli metabolite
pyridine[no description available]medium20azaarene;
mancude organic heteromonocyclic parent;
monocyclic heteroarene;
pyridines		environmental contaminant;
NMR chemical shift reference compound
amitriptyline[no description available]medium10carbotricyclic compound;
tertiary amine		adrenergic uptake inhibitor;
antidepressant;
environmental contaminant;
tropomyosin-related kinase B receptor agonist;
xenobiotic
desipramine[no description available]medium10dibenzoazepine;
secondary amino compound		adrenergic uptake inhibitor;
alpha-adrenergic antagonist;
antidepressant;
cholinergic antagonist;
drug allergen;
EC 3.1.4.12 (sphingomyelin phosphodiesterase) inhibitor;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
serotonin uptake inhibitor
ether[no description available]medium10ether;
volatile organic compound		inhalation anaesthetic;
non-polar solvent;
refrigerant
imipramine[no description available]medium10dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor
mirtazapine[no description available]medium10benzazepine;
tetracyclic antidepressant		alpha-adrenergic antagonist;
anxiolytic drug;
H1-receptor antagonist;
histamine antagonist;
oneirogen;
serotonergic antagonist
pyrilamine[no description available]medium10aromatic ether;
ethylenediamine derivative		H1-receptor antagonist
risperidone[no description available]medium101,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine		alpha-adrenergic antagonist;
dopaminergic antagonist;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
H1-receptor antagonist;
psychotropic drug;
second generation antipsychotic;
serotonergic antagonist
acetonitrile[no description available]medium10aliphatic nitrile;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
NMR chemical shift reference compound;
polar aprotic solvent
nitromethane[no description available]medium10primary nitroalkane;
volatile organic compound		EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
explosive;
NMR chemical shift reference compound;
polar aprotic solvent
quinoxalines[no description available]medium10mancude organic heterobicyclic parent;
naphthyridine;
ortho-fused heteroarene
quinoline[no description available]medium10azaarene;
mancude organic heterobicyclic parent;
ortho-fused heteroarene;
quinolines
benzothiazole[no description available]medium10benzothiazolesenvironmental contaminant;
plant metabolite;
xenobiotic
acetophenone[no description available]medium10acetophenonesanimal metabolite;
photosensitizing agent;
xenobiotic
nitrobenzene[no description available]medium10nitroarene;
nitrobenzenes
benzonitrile[no description available]medium10benzenes;
nitrile
anisole[no description available]medium10monomethoxybenzeneplant metabolite
2-chloropyridine[no description available]medium10monochloropyridine
tetrahydrofuran[no description available]medium10cyclic ether;
oxolanes;
saturated organic heteromonocyclic parent;
volatile organic compound		polar aprotic solvent
isoquinoline[no description available]medium10azaarene;
isoquinolines;
mancude organic heterobicyclic parent;
ortho-fused heteroarene
ethyl acetate[no description available]medium10acetate ester;
ethyl ester;
volatile organic compound		EC 3.4.19.3 (pyroglutamyl-peptidase I) inhibitor;
metabolite;
polar aprotic solvent;
Saccharomyces cerevisiae metabolite
cinnoline[no description available]medium10azaarene;
cinnolines;
mancude organic heterobicyclic parent;
ortho-fused heteroarene
benzoxazoles[no description available]medium101,3-benzoxazoles;
mancude organic heterobicyclic parent
flavone[no description available]medium10flavonesmetabolite;
nematicide
ferrocin c[no description available]medium10
n,n-dimethylbenzamide[no description available]medium10
triphenylphosphine oxide[no description available]medium10phosphine oxideNMR chemical shift reference compound
diphenyl sulfoxide[no description available]medium10sulfoxide
methyl phenyl sulfoxide[no description available]medium10benzenes;
sulfoxide
1,4-dioxane[no description available]medium10dioxane;
volatile organic compound		carcinogenic agent;
metabolite;
NMR chemical shift reference compound;
non-polar solvent
anthranil[no description available]medium102,1-benzoxazoles;
mancude organic heterobicyclic parent
4-methoxybenzonitrile[no description available]medium10
2,6-difluoropyridine[no description available]medium10
1-benzylimidazole[no description available]medium10
6-chloroindole[no description available]medium10indoles
paliperidone[no description available]medium101,2-benzoxazoles;
heteroarylpiperidine;
organofluorine compound;
pyridopyrimidine;
secondary alcohol
l 663581[no description available]medium10
asenapine[no description available]medium105-chloro-2-methyl-2,3,3a,12b-tetrahydrodibenzo[2,3:6,7]oxepino[4,5-c]pyrrole
org 4428[no description available]medium10
4-hydroxymethylpyridine[no description available]medium10
3-acetylpyridine[no description available]medium60aromatic ketone
niacinamide[no description available]medium20pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor
ketanserin[no description available]medium10aromatic ketone;
organofluorine compound;
piperidines;
quinazolines		alpha-adrenergic antagonist;
antihypertensive agent;
cardiovascular drug;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor;
serotonergic antagonist
riboflavin[no description available]medium10flavin;
vitamin B2		anti-inflammatory agent;
antioxidant;
cofactor;
Escherichia coli metabolite;
food colouring;
fundamental metabolite;
human urinary metabolite;
mouse metabolite;
photosensitizing agent;
plant metabolite
pyrazines[no description available]medium10diazine;
pyrazines		Daphnia magna metabolite
2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid[no description available]medium10
cobalt[no description available]medium10cobalt group element atom;
metal allergen		micronutrient
2-acetylpyridine[no description available]medium10aromatic ketone
1,1-diphenyl-2-picrylhydrazyl[no description available]medium10
nickel[no description available]medium10metal allergen;
nickel group element atom		epitope;
micronutrient
niacin[no description available]medium10pyridine alkaloid;
pyridinemonocarboxylic acid;
vitamin B3		antidote;
antilipemic drug;
EC 3.5.1.19 (nicotinamidase) inhibitor;
Escherichia coli metabolite;
human urinary metabolite;
metabolite;
mouse metabolite;
plant metabolite;
vasodilator agent
nad[no description available]medium10organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
6-aminonicotinamide[no description available]medium10aminopyridine;
monocarboxylic acid amide;
primary amino compound		antimetabolite;
EC 1.1.1.44 (NADP(+)-dependent decarboxylating phosphogluconate dehydrogenase) inhibitor;
teratogenic agent
isoniazid[no description available]medium10carbohydrazideantitubercular agent;
drug allergen
cyacetacide[no description available]medium10
hydrazine[no description available]medium10azane;
hydrazines		EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor
acetohexamide[no description available]medium10acetophenones;
N-sulfonylurea		hypoglycemic agent;
insulin secretagogue
histidine[no description available]medium10amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
nadp[no description available]medium10
diethyl pyrocarbonate[no description available]medium10acyclic carboxylic anhydride
4-benzoylpyridine[no description available]medium10aromatic ketone
quercetin[no description available]medium107-hydroxyflavonol;
pentahydroxyflavone		antibacterial agent;
antineoplastic agent;
antioxidant;
Aurora kinase inhibitor;
chelator;
EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor;
geroprotector;
phytoestrogen;
plant metabolite;
protein kinase inhibitor;
radical scavenger
4-aminopyridine[no description available]medium10aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
dextrorphan[no description available]medium10morphinane alkaloid
dizocilpine maleate[no description available]medium10maleate salt;
tetracyclic antidepressant		anaesthetic;
anticonvulsant;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist
kynurenic acid[no description available]medium10monohydroxyquinoline;
quinolinemonocarboxylic acid		G-protein-coupled receptor agonist;
human metabolite;
neuroprotective agent;
nicotinic antagonist;
NMDA receptor antagonist;
Saccharomyces cerevisiae metabolite
glycine[no description available]medium10alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
quinolinic acid[no description available]medium10pyridinedicarboxylic acidEscherichia coli metabolite;
human metabolite;
mouse metabolite;
NMDA receptor agonist
ConditionIndicatedRelationship StrengthStudiesTrials
Carcinoma, Ehrlich Tumor0low10
Ehrlich Ascites Tumor0low10
Extravascular Hemolysis0low10
Gastroduodenal Ulcer0low10
Haemolysis0low10
Hemolysis0low10
Intravascular Hemolysis0low10
Marginal Ulcer0low10
Peptic Ulcer0low10

Research Highlights

Safety/Toxicity (1)

ArticleYear
Novel trans-dichloridoplatinum(II) complexes with 3- and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity.
European journal of medicinal chemistry, Volume: 44, Issue: 5		2009
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]