Page last updated: 2024-11-12
norrisolide
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
norrisolide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 11349389 |
| CHEMBL ID | 514367 |
| SCHEMBL ID | 5513805 |
| MeSH ID | M0465998 |
Synonyms (4)
| Synonym |
|---|
| CHEMBL514367 |
| norrisolide |
| SCHEMBL5513805 |
| [(2r,3r,3ar,6ar)-3-[1-[(1r,3as,7as)-4,4,7a-trimethyl-2,3,3a,5,6,7-hexahydro-1h-inden-1-yl]ethenyl]-5-oxo-3,3a,4,6a-tetrahydro-2h-furo[2,3-b]furan-2-yl] acetate |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID462416 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as golgi fragmentation after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy in presence of PKD inhibitor H89 | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Chemical biology studies on norrisolide. |
| AID462423 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as golgi fragmentation measured after 60 mins following drug washout by Hoechst 3342 staining-based immunofluorescence microscopy | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Chemical biology studies on norrisolide. |
| AID359620 | Inhibition of bee venom PLA2 assessed as inactivation of enzyme at 2 ug/ml | 1992 | Journal of natural products, Dec, Volume: 55, Issue:12 | Phospholipase A2 inhibitors from marine organisms. |
| AID462415 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as enhancement of nocodazole-induced golgi fragmentation after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Chemical biology studies on norrisolide. |
| AID462419 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as transport of GFP-fused VSV G protein from endoplasmic reticulum to golgi after 60 mins by protein transport assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Chemical biology studies on norrisolide. |
| AID462420 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as transport of GFP-fused VSV G protein from fragmented golgi to plasma membrane after 60 mins by protein transport assay | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Chemical biology studies on norrisolide. |
| AID462414 | Golgi-disturbing activity in golgi apparatus of rat NRK cells assessed as microtubule depolymerization-associated golgi fragmentation after 60 mins by Hoechst 3342 staining-based immunofluorescence microscopy in presence of Taxol | 2010 | Bioorganic & medicinal chemistry, Mar-15, Volume: 18, Issue:6 | Chemical biology studies on norrisolide. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (8)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 6 (75.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.94
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.94) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (12.50%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (87.50%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||