pelorol: from the marine sponge Dactylospongia elegans & Petrosaspongia metachromia; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10067895 |
| CHEMBL ID | 487183 |
| SCHEMBL ID | 384771 |
| MeSH ID | M0371596 |
| Synonym |
|---|
| inchi=1/c23h32o4/c1-21(2)8-6-9-22(3)16(21)7-10-23(4)17(22)12-13-18(23)14(20(26)27-5)11-15(24)19(13)25/h11,16-17,24-25h,6-10,12h2,1-5h3/t16-,17+,22-,23+/m0/s |
| CHEMBL487183 |
| pelorol |
| SCHEMBL384771 |
| methyl (4as,6ar,11ar,11bs)-9,10-dihydroxy-4,4,6a,11b-tetramethyl-1,2,3,4a,5,6,11,11a-octahydrobenzo[a]fluorene-7-carboxylate |
Pelorol is a natural product isolated from marine organisms. Pelorol possesses a novel structure with high bioactivity.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Pelorol is a natural product isolated from marine organisms that possesses a novel structure with high bioactivity." | ( Synthesis of Pelorol and Its Analogs and Their Inhibitory Effects on Phosphatidylinositol 3-Kinase. Chen, H; Lu, G; Luo, Y; Weng, J, 2016) | 1.52 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID377198 | Antiplasmodial activity against Plasmodium falciparum NF54 | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8 | Pelorol from the tropical marine sponge Dactylospongia elegans. |
| AID377196 | Antitrypanosomal activity against Trypanosoma rhodesiense | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8 | Pelorol from the tropical marine sponge Dactylospongia elegans. |
| AID377197 | Antiplasmodial activity against Plasmodium falciparum K1 | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8 | Pelorol from the tropical marine sponge Dactylospongia elegans. |
| AID377199 | Toxicity against brine shrimp | 2000 | Journal of natural products, Aug, Volume: 63, Issue:8 | Sesquiterpene quinols/quinones from the Micronesian sponge Petrosaspongia metachromia. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.60) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||