mecarbam : An organic thiophosphate that is O,O-diethyl hydrogen phosphorodithioate in which the hydrogen attached to a sulfur is replaced by a 2-[(ethoxycarbonyl)(methyl)amino]-2-oxoethyl group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 17434 |
| CHEMBL ID | 1417951 |
| CHEBI ID | 38718 |
| SCHEMBL ID | 117570 |
| MeSH ID | M0153049 |
| Synonym |
|---|
| mecarbam [bsi:iso] |
| s-((ethoxycarbonyl)methylcarbamoyl)methyl o,o-diethyl phosphorodithioate |
| p 474 |
| hsdb 1579 |
| ethyl (mercaptoacetyl)methylcarbamate s-ester with o,o-diethyl phosphorodithioate |
| o,o-diethyl s-(n-ethoxycarbonyl-n-methylcarbamoylmethyl)phosphorothiolothionate |
| o,o-diethyl s-(n-ethoxycarbonyl-n-methylcarbamoylmethyl)phosphorodithioate |
| marfotoks |
| brn 1888011 |
| ethyl 6-ethoxy-2-methyl-3-oxo-7-oxa-5-thia-2-aza-6-phosphanonanoate 6-sulfide |
| murphotox |
| o,o-diethyl-s-(3-methyl-2,4-dioxo-5-oxa-3-aza-heptyl)-dithiofosfaat [dutch] |
| s-(n-ethoxycarbonyl-n-methylcarbamoylmethyl)-diethyl phosphorodithioate |
| ms 1143 |
| carbamic acid, (mercaptoacetyl)methyl-, ethyl ester, s-ester with o,o- diethyl phosphorodithioate |
| pestan |
| pennsalt td-72 |
| o,o-dietil-s-(n-etossi-carbonil-n-metil-carbamoil-metil)-ditiofosfato [italian] |
| o,o-diaethyl-s-(3-methyl-2,4-dioxo-5-oxa-3-aza-heptyl)-dithiophosphat [german] |
| afos |
| td 72 |
| caswell no. 340 |
| carbamic acid, (mercaptoacetyl)methyl-, ethyl ester, o,o-diethyl phosphorodithioate |
| phosphorodithioic acid, o,o-diethyl ester, s-ester with ethyl (mercaptoacetyl)methylcarbamate |
| ethyl(((diethoxyphosphinothioyl)thio)acetyl)methylcarbamate |
| 7-oxa-5-thia-2-aza-6-phosphanonanoic acid, 6-ethoxy-2-methyl-3-oxo-, ethyl ester, 6-sulfide |
| mercarbam |
| ethyl n-(diethoxythiophosphorylthio)acetyl-n-methylcarbamate |
| o,o-diethyl s-(n-ethoxycarbonyl-n-methylcarbamoylmethyl) phosphorothiolothionate |
| o,o-diethyl s-(n-methyl-n-carboethoxycarbamoylmethyl) dithiophosphate |
| n-ethoxycarbonyl-n-methylcarbamoylmethyl o,o-diethyl phosphorodithioate |
| murfotox |
| ms 1053 |
| mecarbame [iso-french] |
| epa pesticide chemical code 340100 |
| ethyl (diethoxyphosphinothioylthio)acetyl(methyl)carbamate |
| dithiophosphate de o,o-diethyle et de s-n-methyl n-carboethoxy carbamoylmethyle [french] |
| mecarbame |
| einecs 219-993-9 |
| s-(n-ethoxycarbonyl-n-methylcarbamoylmethyl) o,o-diethyl phosphorodithioate |
| o,o-diethyl s-(((ethoxycarbonyl)methylcarbamoyl)methyl) phosphorodithioate |
| criotox |
| o,o-diethyl s-(n-methyl-n-carboethoxycarbamoylmethyl)dithiophosphate |
| mc 474 |
| NCGC00166159-01 |
| o,o-diethyl s-(n-ethoxycarbonyl-n-methylcarbamoylmethyl) phosphorodithioate |
| ethyl {[(diethoxyphosphorothioyl)sulfanyl]acetyl}methylcarbamate |
| mecarbam |
| CHEBI:38718 , |
| 2595-54-2 |
| ethyl n-(2-diethoxyphosphinothioylsulfanylacetyl)-n-methylcarbamate |
| C18661 |
| unii-u6n6869c7z |
| o,o-diaethyl-s-(3-methyl-2,4-dioxo-5-oxa-3-aza-heptyl)-dithiophosphat |
| o,o-diethyl-s-(3-methyl-2,4-dioxo-5-oxa-3-aza-heptyl)-dithiofosfaat |
| u6n6869c7z , |
| dithiophosphate de o,o-diethyle et de s-n-methyl n-carboethoxy carbamoylmethyle |
| o,o-dietil-s-(n-etossi-carbonil-n-metil-carbamoil-metil)-ditiofosfato |
| NCGC00255735-01 |
| cas-2595-54-2 |
| tox21_302005 |
| dtxsid0042117 , |
| dtxcid8022117 |
| ms-1143 |
| carbamic acid, (mercaptoacetyl)methyl-, ethyl ester, s-ester with o,o-diethyl phosphorodithioate |
| mecarbam [iso] |
| td-72 |
| mecarbam [hsdb] |
| SCHEMBL117570 |
| ethyl [(diethoxyphosphorothioyl)sulfanyl]acetyl(methyl)carbamate # |
| murutox |
| carbamic acid, (mercaptoacetyl)methyl-, ethyl ester, s-ester with o,o-diethyl phosphorodithioic acid |
| muratox |
| pennsalt td 72 |
| KLGMSAOQDHLCOS-UHFFFAOYSA-N |
| CHEMBL1417951 |
| ethyl n-(2-{[diethoxy(sulfanylidene)-$l^{5}-phosphanyl]sulfanyl}acetyl)-n-methylcarbamate |
| mecarbam, pestanal(r), analytical standard |
| mecarbam 10 microg/ml in acetonitrile |
| ethyl 6-ethoxy-2-methyl-3-oxo-7-oxa-5-thia-2-aza-9-phosphanonanoate 6-sulfide, 9ci |
| ethyl [[(diethoxyphosphinothioyl)thio]acetyl]methylcarbamate |
| J-016191 |
| ethyl 2-(diethoxyphosphorothioylthio)acetyl(methyl)carbamate |
| Q27117958 |
| 6-methoxy-indan-1-ylaminehydrochloride |
| 7-oxa-5-thia-2-aza-6-phosphanonanoic acid, 6-ethoxy-2-methyl-3-oxo-,ethyl ester, 6-sulfide |
| CAA59554 |
| Role | Description |
|---|---|
| EC 3.1.1.7 (acetylcholinesterase) inhibitor | An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. |
| acaricide | A substance used to destroy pests of the subclass Acari (mites and ticks). |
| agrochemical | An agrochemical is a substance that is used in agriculture or horticulture. |
| [role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Class | Description |
|---|---|
| organic thiophosphate | |
| organothiophosphate insecticide | |
| carbamate ester | Any ester of carbamic acid or its N-substituted derivatives. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Protein | Taxonomy | Measurement | Average (µ) | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| acetylcholinesterase | Homo sapiens (human) | Potency | 56.3813 | 0.0025 | 41.7960 | 15,848.9004 | AID1347395 |
| phosphopantetheinyl transferase | Bacillus subtilis | Potency | 31.6228 | 0.1413 | 37.9142 | 100.0000 | AID1490 |
| nuclear receptor subfamily 1, group I, member 3 | Homo sapiens (human) | Potency | 27.6390 | 0.0010 | 22.6508 | 76.6163 | AID1224838; AID1224839; AID1224893 |
| retinoid X nuclear receptor alpha | Homo sapiens (human) | Potency | 54.9410 | 0.0008 | 17.5051 | 59.3239 | AID1159527 |
| pregnane X nuclear receptor | Homo sapiens (human) | Potency | 30.6379 | 0.0054 | 28.0263 | 1,258.9301 | AID1346982 |
| peroxisome proliferator-activated receptor delta | Homo sapiens (human) | Potency | 0.1230 | 0.0010 | 24.5048 | 61.6448 | AID743215 |
| aryl hydrocarbon receptor | Homo sapiens (human) | Potency | 15.6557 | 0.0007 | 23.0674 | 1,258.9301 | AID743085; AID743122 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | Homo sapiens (human) | Potency | 54.4827 | 0.0017 | 23.8393 | 78.1014 | AID743083 |
| vitamin D3 receptor isoform VDRA | Homo sapiens (human) | Potency | 50.1187 | 0.3548 | 28.0659 | 89.1251 | AID504847 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | Homo sapiens (human) | Potency | 68.5896 | 0.0006 | 27.2152 | 1,122.0200 | AID743202 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (24.61) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 3 (60.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 2 (40.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||