| Substance | Relationship Strength | Studies | Trials | Classes | Roles |
|---|
gamma-aminobutyric acid
gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.. gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. | 2.07 | 1 | 0 | amino acid zwitterion;
gamma-amino acid;
monocarboxylic acid | human metabolite;
neurotransmitter;
Saccharomyces cerevisiae metabolite;
signalling molecule |
carbamates
[no description available] | 4.92 | 32 | 0 | amino-acid anion | |
chlorpyrifos
Chlorpyrifos: An organothiophosphate cholinesterase inhibitor that is used as an insecticide and as an acaricide.. chlorpyrifos : An organic thiophosphate that is O,O-diethyl hydrogen phosphorothioate in which the hydrogen of the hydroxy group has been replaced by a 3,5,6-trichloropyridin-2-yl group. | 3.14 | 1 | 0 | chloropyridine;
organic thiophosphate | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
insecticide;
xenobiotic |
diazinon
Diazinon: A cholinesterase inhibitor that is used as an organothiophosphorus insecticide.. diazinon : A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4. | 3.14 | 1 | 0 | organic thiophosphate;
pyrimidines | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
environmental contaminant;
nematicide;
xenobiotic |
propargite
Omite: structure | 2.05 | 1 | 0 | sulfite ester;
terminal acetylenic compound | sulfite ester acaricide |
butyl phosphorotrithioate
butyl phosphorotrithioate: a herbicide | 2.05 | 1 | 0 | organic thiophosphate | defoliant |
piperonyl butoxide
[no description available] | 2.05 | 1 | 0 | benzodioxoles | pesticide synergist |
4-butyrolactone
4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2. | 2.02 | 1 | 0 | butan-4-olide | metabolite;
neurotoxin |
acrylonitrile
[no description available] | 2.21 | 1 | 0 | aliphatic nitrile;
volatile organic compound | antifungal agent;
carcinogenic agent;
fungal metabolite;
mutagen;
polar aprotic solvent |
oxazoles
Oxazoles: Five-membered heterocyclic ring structures containing an oxygen in the 1-position and a nitrogen in the 3-position, in distinction from ISOXAZOLES where they are at the 1,2 positions.. 1,3-oxazole : A five-membered monocyclic heteroarene that is an analogue of cyclopentadiene with O in place of CH2 at position 1 and N in place of CH at position 3.. oxazole : An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom. | 2.49 | 2 | 0 | 1,3-oxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene | |
hydrazine
diamine : Any polyamine that contains two amino groups. | 4.88 | 31 | 0 | azane;
hydrazines | EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor |
thiazolidines
Thiazolidines: Reduced (protonated) form of THIAZOLES. They can be oxidized to THIAZOLIDINEDIONES. | 2.25 | 1 | 0 | thiazolidine | |
thiometon
thiometon: minor descriptor (72-85); on-line & Index Medicus search INSECTICIDES, ORGANOTHIOPHOSPHATE (72-85); RN given refers to parent cpd | 3.14 | 1 | 0 | organic thiophosphate;
organosulfur compound;
organothiophosphate insecticide | acaricide;
agrochemical;
EC 3.1.1.7 (acetylcholinesterase) inhibitor |
paraquat
Paraquat: A poisonous dipyridilium compound used as contact herbicide. Contact with concentrated solutions causes irritation of the skin, cracking and shedding of the nails, and delayed healing of cuts and wounds.. paraquat : An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions. | 3.14 | 1 | 0 | organic cation | geroprotector;
herbicide |
dienochlor
dienochlor: structure | 2.05 | 1 | 0 | organochlorine compound | |
gold
Gold: A yellow metallic element with the atomic symbol Au, atomic number 79, and atomic weight 197. It is used in jewelry, goldplating of other metals, as currency, and in dental restoration. Many of its clinical applications, such as ANTIRHEUMATIC AGENTS, are in the form of its salts. | 3.14 | 1 | 0 | copper group element atom;
elemental gold | |
ferric chloride
ferric chloride: RN given refers to cpd with MF of Fe-Cl3; used to induce experimental arterial thrombosis to evaluate antithrombotic agents | 7.6 | 1 | 0 | iron coordination entity | astringent;
Lewis acid |
carbendazim
carbendazim: carcinogen when combined with sodium nitrite; principle metabolite of thiophanate methyl & benomyl; structure. carbendazim : A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables. | 3.14 | 1 | 0 | benzimidazole fungicide;
benzimidazoles;
benzimidazolylcarbamate fungicide;
carbamate ester | antifungal agrochemical;
antinematodal drug;
metabolite;
microtubule-destabilising agent |
isopropyl 4,4'-dibromobenzilate
isopropyl 4,4'-dibromobenzilate: active substance in fumigant strips for mites | 2.05 | 1 | 0 | | |
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid. | 2.98 | 4 | 0 | benzenes;
phenyl acetates | |
amitraz
amitraz: ixodicide (tick control); structure. amitraz : A tertiary amino compound that is 1,3,5-triazapenta-1,4-diene substituted by a methyl group at position 3 and 2,4-dimethylphenyl groups at positions 1 and 5. | 2.05 | 1 | 0 | formamidines;
tertiary amino compound | acaricide;
environmental contaminant;
insecticide;
xenobiotic |
triazoles
Triazoles: Heterocyclic compounds containing a five-membered ring with two carbon atoms and three nitrogen atoms with the molecular formula C2H3N3.. triazoles : An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms. | 2.21 | 1 | 0 | 1,2,3-triazole | |
clofentezine
clofentezine: acaricide, primarily a mite ovicide; structure given in first source. clofentezine : A tetrazine that is 1,2,4,5-tetrazine in which both of the hydrogens have been replaced by o-chlorophenyl groups. | 2.46 | 2 | 0 | monochlorobenzenes;
organochlorine acaricide;
tetrazine | mite growth regulator;
tetrazine acaricide |
tetraconazole
tetraconazole : A racemate comprising equal amounts of (R)- and (S)-tetraconazole. A fungicide used to control a range of fungal infections including powdery mildew, rusts, bunt, loose smut and scab.. 1-[2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl]1,2,4-triazole : A member of the class of triazoles that is 1,2,4-triazole substituted at position 1 by a 2-(2,4-dichlorophenyl)-3-(1,1,2,2-tetrafluoroethoxy)propyl group. | 7.21 | 1 | 0 | dichlorobenzene;
ether;
organofluorine compound;
triazoles | |
4-chloro-n-((4-(1,1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1h-pyrazole-5-carboxamide
[no description available] | 2.75 | 3 | 0 | pyrazole acaricide;
pyrazole insecticide | mitochondrial NADH:ubiquinone reductase inhibitor |
fenazaquin
fenazaquin: an experimental miticide | 2.05 | 1 | 0 | quinazolines | acaricide;
mitochondrial NADH:ubiquinone reductase inhibitor |
pyriproxyfen
pyriproxyfen: an insect growth regulator; RN given refers to cpd without isomeric designation. pyriproxyfen : An aromatic ether that consists of propylene glycol having a 2-pyridyl group at the O-1 position and a 4-phenoxyphenyl group at the O-3 position. | 7.17 | 1 | 0 | aromatic ether;
pyridines | juvenile hormone mimic |
pyridaben
[no description available] | 2.74 | 3 | 0 | organochlorine acaricide;
organochlorine insecticide;
pyridazinone | mitochondrial NADH:ubiquinone reductase inhibitor |
chlorfenapyr
chlorfenapyr: an experimental pour-on formulation, a new generation pyrethroid available to producers. chlorfenapyr : A member of the class of pyrroles that is 4-bromo-1H-pyrrole-3-carbonitrile which is substituted at positions 1, 2 and 5 by ethoxymethyl, p-chlorophenyl and trifluoromethyl groups, respectively. A proinsecticide used for termite control and crop protection against several insects and mite pests. | 2.05 | 1 | 0 | hemiaminal ether;
monochlorobenzenes;
nitrile;
organochlorine acaricide;
organochlorine insecticide;
organofluorine acaricide;
organofluorine insecticide;
pyrroles | proacaricide;
proinsecticide |
acequinocyl
acequinocyl: structure in first source. acequinocyl : An acetate ester consisting of 1,4-naphthoquinone bearing acetoxy and dodecyl substituents at positions 2 and 3 respectively. | 3.58 | 8 | 0 | 1,4-naphthoquinones;
acetate ester | acaricide;
mitochondrial cytochrome-bc1 complex inhibitor |
methoxyfenozide
methoxyfenozide: structure in first source. methoxyfenozide : A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by 3-methoxy-2-methylbenzoyl, 3,5-dimethylbenzoyl, and tert-butyl groups respectively. | 7.17 | 1 | 0 | carbohydrazide;
monomethoxybenzene | environmental contaminant;
insecticide;
xenobiotic |
diazene
[no description available] | 3.24 | 5 | 0 | nitrogen hydride | |
borneo
Borneo: An island in the Malay Archipelago, east of Sumatra, north of Java, and west of Celebes. It is the third largest island in the world. Its name is a Portuguese alteration of BRUNEI, located on it. (From Webster's New Geographical Dictionary, 1988, p163; Room, Brewer's Dictionary of Names, 1992, p73) | 3.34 | 6 | 0 | organofluorine acaricide | |
spirodiclofen
spirodiclofen: an acaricide | 2.96 | 4 | 0 | dichlorobenzene;
gamma-lactone;
organochlorine acaricide;
oxaspiro compound | |
diethyl maleate
diethyl maleate : A maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. A colourless liquid at room temperature (m.p. -10degreeC) with boiling point 220degreeC at 1 atm., it is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis. | 2.05 | 1 | 0 | ethyl ester;
maleate ester | glutathione depleting agent |
bifenthrin
bifenthrin: a type I pyrethroid. bifenthrin : A carboxylic ester obtained by formal condensation of cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylic acid and [(2-methyl-1,1'-biphenyl)-3-yl]methanol.. kappa-bifenthrin : A carboxylic ester obtained by formal condensation of the carboxy group of (1R,3R)-3-[(1Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropanecarboxylic acid with the hydroxy group of [(2-methyl-1,1'-biphenyl)-3-yl]methanol. | 3.11 | 4 | 0 | carboxylic ester;
cyclopropanecarboxylate ester;
cyclopropanes;
organochlorine compound;
organofluorine compound | pyrethroid ester acaricide;
pyrethroid ester insecticide |
flucycloxuron
[no description available] | 2.05 | 1 | 0 | flucycloxuron | |
fenpyroximate
fenpyroximate: structure in first source | 2.05 | 1 | 0 | pyrazole acaricide;
tert-butyl ester | mitochondrial NADH:ubiquinone reductase inhibitor |
spiromesifen
spiromesifen: insecticide; structure in first source. spiromesifen : A butenolide that is but-2-en-4-olide bearing a 2,4,6-trimethylphenyl group at position 3, a 3,3-dimethylbutyryloxy group at position 4 and a spiro-fused cyclopentyl ring at position 5. | 2.75 | 3 | 0 | butenolide | insecticide |
mk 936
[no description available] | 2.46 | 2 | 0 | | |
fluacrypyrim
fluacrypyrim: a STAT3 activation inhibitor and antineoplastic agent; structure in first source | 2.05 | 1 | 0 | enoate ester;
enol ether;
methyl ester;
organofluorine acaricide;
pyrimidines | mitochondrial cytochrome-bc1 complex inhibitor |
medigoxin
spirotetramat: for the control of a broad spectrum of sucking insects; structure in first source. spirotetramat : An azaspiro compound that is methoxycyclohexane which is fused at position 4 to the 5-position of a 1,5-dihydro-2H-pyrrol-2-one that is substituted at positions 3 and 4 by 2,5-dimethylphenyl and (ethoxycarbonyl)oxy groups, respectively (the cis isomer). It is a proinsecticide (via hydrolysis of the ethyl carbonate group to give the corresponding 4-hydroxypyrrol-2-one, "spirotetramat-enol") and is used for the control of a wide range of sucking insects on fruit and potato crops. | 2.06 | 1 | 0 | | |
cyflumetofen
cyflumetofen: acaricide; structure in first source. cyflumetofen : A racemate comprising equimolar amounts of (R)- and (S)-cyflumetofen. A proacaricide (via ester hydrolysis and subsequent decarboxylation), it is used to control phytophagous mites at all development stages in a variety of fruit crops. It acts as an inhibitor of complex II of mitochondrial electron transport chain.. 2-methoxyethyl 2-(4-tert-butylphenyl)-2-cyano-3-oxo-3-[2-(trifluoromethyl)phenyl]propanoate : A nitrile that is acetonitrile in which the methyl hydrogens have been replaced by o-trifluoromethylbenzoyl, p-tert-butylphenyl, and (2-methoxyethoxy)carbonyl groups. | 7.25 | 1 | 0 | (trifluoromethyl)benzenes;
2-methoxyethyl ester;
beta-ketoester;
nitrile | |
ubiquinone
Ubiquinone: A lipid-soluble benzoquinone which is involved in ELECTRON TRANSPORT in mitochondrial preparations. The compound occurs in the majority of aerobic organisms, from bacteria to higher plants and animals. | 2.06 | 1 | 0 | | |
cyenopyrafen
cyenopyrafen: an acaricide; structure in first source. cyenopyrafen : A member of the class of pyrazoles that is ethene in which the hydrogens at position 1 have been replaced by p-tert-butylphenyl and cyano groups, while the hydrogens at position 2 have been replaced by pivaloyloxy and 1,3,4-trimethylpyrazol-5-yl groups (the E isomer). A proacaricide (by hydrolysis of the pivalate ester linkage to give the corresponding enol), it was formerly used for the control of mites in fruit, vegetables and tea. | 7.52 | 2 | 0 | nitrile;
pivalate ester;
pyrazoles | agrochemical;
proacaricide |
pyrethrins
[no description available] | 2.69 | 2 | 0 | | |