Page last updated: 2024-09-27

Adenomyoma

A benign neoplasm of muscle (usually smooth muscle) with glandular elements. It occurs most frequently in the uterus and uterine ligaments. (Stedman, 25th ed)

Synonyms(1)

Synonym
Adenomyoma

Research Excerpts

Treatment

ExcerptReference
"To assess the effectiveness of treating adenomyomata with laparoscopic bipolar coagulation."( Haselkorn, JS; Milim, SJ; Nathanson, HG; Phillips, DR, 1996)

Research

Studies (44)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's11 (25.00)12.5806
2000's14 (31.82)18.1394
2010's14 (31.82)28.8240
2020's5 (11.36)9.53
DrugIndicatedRelationship StrengthStudiesTrials
aminolevulinic acid0low10
tranexamic acid0low10
bromodeoxyuridine0low10
medroxyprogesterone acetate0low30
levonorgestrel0low30
sulfur hexafluoride0low10
iodinated glycerol0low10
danazol0low10
mifepristone0low10
fluorodeoxyglucose f180low20
o-(chloroacetylcarbamoyl)fumagillol0low10
n-acetylneuraminic acid0low10
elastin0low10
bromochloroacetic acid0low40
leuprolide0medium62
sesquiterpenes0low10
tamoxifen0low20
goserelin0medium21
barium0low10
elagolix0low10
lhrh, ala(6)-gly(10)-ethylamide-0low10
trelstar0low10
transforming growth factor beta0low10
alcian blue0low10

Protein Targets (328)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
Chain A, Beta-lactamase5005
bromodomain adjacent to zinc finger domain 2B4004
geminin8008
Gamma-aminobutyric acid receptor subunit rho-10101
Glutamate receptor 10101
Glutamate receptor 20101
Glutamate receptor 30101
Glutamate receptor ionotropic, kainate 30101
Solute carrier family 15 member 10101
Glutamate receptor 40101
Solute carrier family 15 member 10101
Solute carrier family 15 member 20101
RAR-related orphan receptor gamma9009
AR protein9009
aldehyde dehydrogenase 1 family, member A13003
nuclear receptor subfamily 1, group I, member 39009
retinoic acid nuclear receptor alpha variant 18008
thyroid stimulating hormone receptor5005
nuclear factor erythroid 2-related factor 2 isoform 18008
Cellular tumor antigen p538008
Nuclear receptor ROR-gamma3003
interleukin 82002
pregnane X receptor4004
ATAD5 protein, partial5005
TDP1 protein8008
Microtubule-associated protein tau2002
progesterone receptor8008
glucocorticoid receptor [Homo sapiens]7007
retinoid X nuclear receptor alpha8008
estrogen-related nuclear receptor alpha8008
pregnane X nuclear receptor9009
estrogen nuclear receptor alpha9009
arylsulfatase A2002
IDH13003
euchromatic histone-lysine N-methyltransferase 26006
nuclear receptor subfamily 1, group I, member 24004
cellular tumor antigen p53 isoform a2002
Nuclear hormone receptor family member daf-120011
chromobox protein homolog 14004
nuclear factor erythroid 2-related factor 2 isoform 24004
thyroid hormone receptor beta isoform 29009
serine/threonine-protein kinase mTOR isoform 13003
oxysterols receptor LXR-beta isoform 10011
urokinase-type plasminogen activator precursor2002
plasminogen precursor2002
urokinase plasminogen activator surface receptor precursor2002
peripheral myelin protein 224004
survival motor neuron protein isoform d2002
muscarinic acetylcholine receptor M11001
Voltage-dependent calcium channel gamma-2 subunit6006
Thymidine kinase, cytosolic0101
Glutamate receptor 26006
Thymidine phosphorylase0001
Thymidylate kinase0101
Spike glycoprotein4015
Thymidine kinase0001
Thymidylate kinase0101
ATPase family AAA domain-containing protein 56006
Ataxin-26006
glp-1 receptor, partial2002
hypoxia-inducible factor 1 alpha subunit4004
SMAD family member 25005
SMAD family member 35005
GLI family zinc finger 36006
estrogen receptor 2 (ER beta)5005
cytochrome P450 family 3 subfamily A polypeptide 46006
farnesoid X nuclear receptor5005
G5005
cytochrome P450 2D63003
peroxisome proliferator-activated receptor delta5005
peroxisome proliferator activated receptor gamma6006
vitamin D (1,25- dihydroxyvitamin D3) receptor7007
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
v-jun sarcoma virus 17 oncogene homolog (avian)6006
Histone H2A.x4004
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
heat shock protein beta-14004
ATP-binding cassette sub-family C member 30505
Multidrug resistance-associated protein 40505
Bile salt export pump0505
Rap guanine nucleotide exchange factor 31001
Interferon beta6006
HLA class I histocompatibility antigen, B alpha chain 5005
Estrogen receptor17312
Glucocorticoid receptor16312
Sex hormone-binding globulin0022
Cytochrome P450 1A20101
Glycine receptor subunit alpha-10606
Aldo-keto reductase family 1 member B10404
Alpha-2A adrenergic receptor0606
Adenosine receptor A30404
Cytochrome P450 2C9 0202
Beta-3 adrenergic receptor0404
Androgen receptor0808
Alpha-1B adrenergic receptor0404
Alpha-2B adrenergic receptor0808
Alpha-2C adrenergic receptor0404
Muscarinic acetylcholine receptor M30404
Glycine receptor subunit beta0606
Substance-K receptor0404
D(1A) dopamine receptor0606
Glycine receptor subunit alpha-20606
Sodium-dependent noradrenaline transporter 0404
Glycine receptor subunit alpha-30606
5-hydroxytryptamine receptor 2A0617
Sodium-dependent serotonin transporter0404
Mu-type opioid receptor0606
D(3) dopamine receptor0606
Kappa-type opioid receptor0606
Alpha-1A adrenergic receptor0404
Cytochrome P450 2J20202
Sodium-dependent dopamine transporter 0404
Inositol hexakisphosphate kinase 15005
Canalicular multispecific organic anion transporter 10505
cytochrome P450 2C9, partial5005
Chain A, JmjC domain-containing histone demethylation protein 3A3003
apical membrane antigen 1, AMA13003
aryl hydrocarbon receptor1001
mu-type opioid receptor isoform MOR-10011
importin subunit beta-1 isoform 11001
snurportin-11001
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase iota isoform a (long)4004
DNA polymerase kappa isoform 11001
Vpr1001
D(3) dopamine receptor isoform e1001
5-hydroxytryptamine receptor 2A0011
D0101
5-hydroxytryptamine receptor 1A0606
D(2) dopamine receptor0112
vitamin D3 receptor isoform VDRA3003
TAR DNA-binding protein 431001
Rap guanine nucleotide exchange factor 41001
Gonadotropin-releasing hormone receptor0101
Gonadotropin-releasing hormone receptor0202
USP1 protein, partial3003
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a3003
transcriptional regulator ERG isoform 33003
DNA polymerase beta1001
lamin isoform A-delta104004
Progesterone receptor05310
5-hydroxytryptamine receptor 40404
Beta-2 adrenergic receptor0202
Beta-1 adrenergic receptor0404
5-hydroxytryptamine receptor 1A0112
Cytochrome P450 2D60101
D(2) dopamine receptor0415
D(4) dopamine receptor0213
Histamine H2 receptor0606
Alpha-1D adrenergic receptor0404
5-hydroxytryptamine receptor 2C0415
5-hydroxytryptamine receptor 1B0505
Histamine H1 receptor0202
5-hydroxytryptamine receptor 2B0404
5-hydroxytryptamine receptor 60404
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE1001
Chain A, Cruzipain2002
PINK11001
nonstructural protein 12002
Parkin1001
cytochrome P450 3A4 isoform 12002
neuropeptide S receptor isoform A2002
Gamma-aminobutyric acid receptor subunit pi2002
Mineralocorticoid receptor 1316
Androgen receptor1438
Gamma-aminobutyric acid receptor subunit beta-12002
Gamma-aminobutyric acid receptor subunit delta2002
Gamma-aminobutyric acid receptor subunit gamma-22002
Androgen receptor0011
Gamma-aminobutyric acid receptor subunit alpha-52002
Gamma-aminobutyric acid receptor subunit alpha-32002
Gamma-aminobutyric acid receptor subunit gamma-12002
Gamma-aminobutyric acid receptor subunit alpha-22002
Gamma-aminobutyric acid receptor subunit alpha-42002
Gamma-aminobutyric acid receptor subunit gamma-32002
Gamma-aminobutyric acid receptor subunit alpha-62002
Alpha-synuclein2002
Aldo-keto reductase family 1 member C30101
Aldo-keto reductase family 1 member C2 0101
Gamma-aminobutyric acid receptor subunit alpha-12002
Gamma-aminobutyric acid receptor subunit beta-32002
Guanine nucleotide-binding protein G2002
Gamma-aminobutyric acid receptor subunit beta-22002
Aldo-keto reductase family 1 member C10101
GABA theta subunit2002
Estrogen receptor beta1539
Gamma-aminobutyric acid receptor subunit epsilon2002
Chain A, TYROSYL-DNA PHOSPHODIESTERASE1001
Chain A, PROGESTERONE RECEPTOR0101
Chain A, Ferritin light chain2002
Glucocorticoid receptor 0101
dopamine D1 receptor1001
thioredoxin reductase1001
Fumarate hydratase2002
GLS protein1001
hypothetical protein, conserved1001
regulator of G-protein signaling 42002
EWS/FLI fusion protein2002
polyprotein2002
activating transcription factor 62002
D(1A) dopamine receptor2002
huntingtin isoform 21001
atrial natriuretic peptide receptor 2 precursor1001
nuclear receptor ROR-gamma isoform 12002
M-phase phosphoprotein 82002
histone acetyltransferase KAT2A isoform 11001
Prostaglandin G/H synthase 10101
Tyrosine-protein kinase Fyn0202
Tegument protein VP160011
Glucocorticoid receptor0113
Glucocorticoid receptor0101
Cytochrome P450 3A40303
Coagulation factor VII0101
Cytochrome P450 2C80101
Thyroid hormone receptor alpha0101
Thyroid hormone receptor beta0101
Steroid 17-alpha-hydroxylase/17,20 lyase 0101
Polyunsaturated fatty acid lipoxygenase ALOX150101
Tissue factor0101
ATP-dependent translocase ABCB10011
Prostaglandin G/H synthase 10202
Adenosine receptor A10011
Adenosine receptor A2a0011
Substance-P receptor0101
D(1A) dopamine receptor2002
Mitogen-activated protein kinase 140101
Progesterone receptor0011
Sigma non-opioid intracellular receptor 10404
Glucocorticoid receptor0101
ATP-dependent phosphofructokinase1001
Sialidase-40101
Sialidase-10101
Sialidase-30101
Sialidase-20101
Methionine aminopeptidase 20202
Chain A, CES1 protein0101
acetylcholinesterase1001
phosphopantetheinyl transferase1001
PPM1D protein1001
DNA polymerase III, partial1001
caspase 7, apoptosis-related cysteine protease1001
67.9K protein1001
glucocerebrosidase1001
caspase-31001
thyrotropin-releasing hormone receptor1001
Caspase-71001
Spike glycoprotein0011
Replicase polyprotein 1ab0011
cytochrome P450 2D6 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
interferon gamma precursor0001
caspase-31001
ubiquitin-conjugating enzyme E2 N0101
ras-related protein Rab-9A1001
streptokinase A precursor0011
lethal factor (plasmid)1001
Polyunsaturated fatty acid lipoxygenase ALOX15B1001
Transmembrane protease serine 20011
Serine/threonine-protein kinase D30101
Epidermal growth factor receptor0101
Lysosomal acid glucosylceramidase0011
Receptor tyrosine-protein kinase erbB-20101
Integrin beta-31001
Protein kinase C gamma type0101
Protein kinase C alpha type0101
Protein kinase C beta type0101
Estrogen receptor0012
Tyrosine-protein kinase Lck0101
Procathepsin L0011
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
ATP-dependent translocase ABCB10213
Integrin alpha-IIb1001
Muscarinic acetylcholine receptor M50202
Protein kinase C delta type0101
Protein kinase C epsilon type0101
Protein kinase C zeta type0101
Polyunsaturated fatty acid 5-lipoxygenase0101
Replicase polyprotein 1a0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Replicase polyprotein 1ab0011
Muscarinic acetylcholine receptor M10202
Steroid hormone receptor ERR10101
Transcriptional activator protein LuxR0101
Angiotensin-converting enzyme0202
Protein kinase C alpha type0101
Cytochrome P450 2B60101
UDP-glucuronosyltransferase 1A40001
Thromboxane-A synthase 0101
Protein kinase C eta type0101
Substance-P receptor0202
Adenosine receptor A2a0202
B2 bradykinin receptor0202
Adenosine receptor A10202
Melanocortin receptor 40202
C-8 sterol isomerase0101
Melanocortin receptor 50202
Delta-type opioid receptor0202
Protein kinase C iota type0101
Melanocortin receptor 30202
Histamine H2 receptor1001
Estrogen-related receptor gamma0101
Protein kinase C gamma type0101
Protein kinase C beta type0101
Phospholipase D1 0101
Protein kinase C epsilon type0101
Protein kinase C theta type0101
Protein kinase C zeta type0101
Protein kinase C delta type0101
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform0101
Potassium voltage-gated channel subfamily H member 20202
Platelet-activating factor acetylhydrolase0101
Phospholipase D10101
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase0213
Serine/threonine-protein kinase D10101
Estrogen receptor beta0012
Protein kinase C eta type0101
Nuclear receptor subfamily 3 group C member 3 0202
Emopamil-binding protein-like0101
Angiotensin-converting enzyme 2 0011
7-dehydrocholesterol reductase0112
Protein kinase C theta type0101
Chain A, PLASMINOGEN0011
Chain A, PLASMINOGEN0011
Plasminogen0213
Urokinase-type plasminogen activator0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]