2-(4-bromophenyl)-4-methyl-1H-pyrazol-5-one

2-(4-bromophenyl)-4-methyl-1H-pyrazol-5-one, also known as **4-bromoantipyrine**, is a synthetic organic compound belonging to the pyrazolone family.

Here's a breakdown of its characteristics and importance:

**Structure and Properties:**

* **Structure:** 4-bromoantipyrine has a pyrazolone ring system with a bromine atom attached to the phenyl ring at the para position and a methyl group attached at the 4-position.
* **Appearance:** It's a white to off-white crystalline powder.
* **Solubility:** Soluble in various organic solvents like ethanol, chloroform, and ether.
* **Melting Point:** Around 110-112°C.

**Research Importance:**

4-bromoantipyrine is important for research in several fields, primarily due to its:

* **Pharmacological Activity:**
* **Anti-inflammatory:** 4-bromoantipyrine exhibits significant anti-inflammatory activity, similar to other pyrazolone derivatives like antipyrine.
* **Analgesic:** It also possesses analgesic (pain-relieving) properties.
* **Antipyretic:** 4-bromoantipyrine can reduce fever.
* **Chemical Reactivity:**
* **Versatile Building Block:** It serves as a starting material for the synthesis of a wide range of pyrazolone derivatives with potentially diverse pharmacological actions.
* **Modification Potential:** The bromine atom on the phenyl ring can be easily modified through various chemical reactions, allowing the creation of new compounds with tailored properties.

**Research Applications:**

* **Drug Discovery:** 4-bromoantipyrine is used in the development of new drugs for inflammation, pain, and fever.
* **Chemical Synthesis:** Its reactivity and versatility make it a valuable building block for the synthesis of novel compounds with diverse biological activities.
* **Material Science:** 4-bromoantipyrine's properties have been investigated for potential applications in materials science, including optical materials and polymers.

**Note:** While 4-bromoantipyrine has shown promise in research, it's important to note that its use in human medicine might be limited due to potential side effects and the availability of safer alternatives.

If you're interested in learning more about specific research applications or the detailed pharmacological mechanisms of 4-bromoantipyrine, you can search for research articles on relevant databases like PubMed or Google Scholar.