| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Chain A, JmjC domain-containing histone demethylation protein 3A | 2 | 0 | 0 | 2 |
| Luciferase | 4 | 0 | 0 | 4 |
| USP1 protein, partial | 7 | 0 | 0 | 7 |
| TDP1 protein | 9 | 0 | 0 | 9 |
| Microtubule-associated protein tau | 3 | 0 | 0 | 3 |
| AR protein | 17 | 0 | 0 | 17 |
| aldehyde dehydrogenase 1 family, member A1 | 7 | 0 | 0 | 7 |
| glucocorticoid receptor [Homo sapiens] | 10 | 0 | 0 | 10 |
| estrogen nuclear receptor alpha | 15 | 0 | 0 | 15 |
| peroxisome proliferator activated receptor gamma | 7 | 0 | 0 | 7 |
| euchromatic histone-lysine N-methyltransferase 2 | 8 | 0 | 0 | 8 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 9 | 0 | 0 | 9 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| thyroid hormone receptor beta isoform 2 | 9 | 0 | 0 | 9 |
| flap endonuclease 1 | 2 | 0 | 0 | 2 |
| serine/threonine-protein kinase PLK1 | 1 | 0 | 0 | 1 |
| eyes absent homolog 2 isoform a | 1 | 0 | 0 | 1 |
| DNA polymerase eta isoform 1 | 1 | 0 | 0 | 1 |
| geminin | 10 | 0 | 0 | 10 |
| peripheral myelin protein 22 | 5 | 0 | 0 | 5 |
| survival motor neuron protein isoform d | 4 | 0 | 0 | 4 |
| histone acetyltransferase KAT2A isoform 1 | 2 | 0 | 0 | 2 |
| ATP-binding cassette sub-family C member 3 | 0 | 11 | 0 | 11 |
| Multidrug resistance-associated protein 4 | 0 | 11 | 0 | 11 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Bile salt export pump | 0 | 12 | 0 | 12 |
| Rap guanine nucleotide exchange factor 3 | 2 | 0 | 0 | 2 |
| Cellular tumor antigen p53 | 7 | 0 | 0 | 7 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| aryl hydrocarbon receptor | 5 | 0 | 0 | 5 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0 | 3 | 0 | 3 |
| Glycine receptor subunit alpha-1 | 0 | 0 | 1 | 1 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | 0 | 2 | 0 | 2 |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase | 0 | 2 | 0 | 2 |
| Canalicular multispecific organic anion transporter 1 | 0 | 10 | 0 | 10 |
| hypoxia-inducible factor 1 alpha subunit | 4 | 0 | 0 | 4 |
| RAR-related orphan receptor gamma | 9 | 0 | 0 | 9 |
| SMAD family member 2 | 6 | 0 | 0 | 6 |
| SMAD family member 3 | 6 | 0 | 0 | 6 |
| GLI family zinc finger 3 | 7 | 0 | 0 | 7 |
| estrogen receptor 2 (ER beta) | 4 | 0 | 0 | 4 |
| progesterone receptor | 6 | 0 | 0 | 6 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 5 | 0 | 0 | 5 |
| retinoic acid nuclear receptor alpha variant 1 | 9 | 0 | 0 | 9 |
| retinoid X nuclear receptor alpha | 7 | 0 | 0 | 7 |
| estrogen-related nuclear receptor alpha | 11 | 0 | 0 | 11 |
| farnesoid X nuclear receptor | 5 | 0 | 0 | 5 |
| pregnane X nuclear receptor | 8 | 0 | 0 | 8 |
| G | 3 | 0 | 0 | 3 |
| cytochrome P450 2D6 | 3 | 0 | 0 | 3 |
| peroxisome proliferator-activated receptor delta | 7 | 0 | 0 | 7 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 7 | 0 | 0 | 7 |
| activating transcription factor 6 | 2 | 0 | 0 | 2 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 4 | 0 | 0 | 4 |
| heat shock protein beta-1 | 5 | 0 | 0 | 5 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 7 | 0 | 0 | 7 |
| Voltage-dependent calcium channel gamma-2 subunit | 4 | 0 | 0 | 4 |
| Interferon beta | 4 | 0 | 0 | 4 |
| HLA class I histocompatibility antigen, B alpha chain | 3 | 0 | 0 | 3 |
| Glutamate receptor 2 | 4 | 0 | 0 | 4 |
| Inositol hexakisphosphate kinase 1 | 3 | 0 | 0 | 3 |
| cytochrome P450 2C9, partial | 3 | 0 | 0 | 3 |
| mitogen-activated protein kinase 1 | 3 | 0 | 0 | 3 |
| nuclear receptor ROR-gamma isoform 1 | 5 | 0 | 0 | 5 |
| Cytochrome P450 2C9 | 0 | 4 | 2 | 6 |
| 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 1 | 0 | 1 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | 0 | 2 | 0 | 2 |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 1 | 1 | 2 |
| thioredoxin glutathione reductase | 3 | 0 | 0 | 3 |
| thyroid stimulating hormone receptor | 2 | 0 | 0 | 2 |
| regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
| EWS/FLI fusion protein | 2 | 0 | 0 | 2 |
| Bloom syndrome protein isoform 1 | 3 | 0 | 0 | 3 |
| ubiquitin carboxyl-terminal hydrolase 2 isoform a | 1 | 0 | 0 | 1 |
| muscarinic acetylcholine receptor M1 | 3 | 0 | 0 | 3 |
| lamin isoform A-delta10 | 5 | 0 | 0 | 5 |
| Voltage-dependent calcium channel subunit alpha-2/delta-1 | 0 | 1 | 0 | 1 |
| ATP-dependent phosphofructokinase | 4 | 0 | 0 | 4 |
| acetylcholinesterase | 2 | 0 | 0 | 2 |
| thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 4 | 0 | 0 | 4 |
| cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
| Integrin beta-3 | 2 | 0 | 0 | 2 |
| Integrin alpha-IIb | 2 | 0 | 0 | 2 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 4 | 0 | 0 | 4 |
| Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
| thioredoxin reductase | 3 | 0 | 0 | 3 |
| GLS protein | 2 | 0 | 0 | 2 |
| IDH1 | 2 | 0 | 0 | 2 |
| chromobox protein homolog 1 | 6 | 0 | 0 | 6 |
| cytochrome P450 3A4 isoform 1 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit pi | 4 | 0 | 0 | 4 |
| Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit delta | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 4 | 0 | 0 | 4 |
| Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 4 | 0 | 0 | 4 |
| Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 4 | 0 | 0 | 4 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 4 | 0 | 0 | 4 |
| Potassium voltage-gated channel subfamily H member 2 | 0 | 1 | 0 | 1 |
| Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
| Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
| Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
| Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
| GABA theta subunit | 4 | 0 | 0 | 4 |
| Multidrug and toxin extrusion protein 1 | 0 | 2 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit epsilon | 4 | 0 | 0 | 4 |
| Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Polyunsaturated fatty acid 5-lipoxygenase | 0 | 1 | 0 | 3 |
| Hormone-sensitive lipase | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member C4 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A1 | 0 | 1 | 0 | 1 |
| Caspase-1 | 0 | 1 | 0 | 1 |
| Adenosine receptor A2a | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 2 |
| Aldo-keto reductase family 1 member C3 | 0 | 1 | 0 | 1 |
| Caspase-3 | 0 | 1 | 0 | 1 |
| Caspase-4 | 0 | 1 | 0 | 1 |
| Cytochrome P450 2J2 | 0 | 2 | 0 | 2 |
| Caspase-5 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member C2 | 0 | 1 | 0 | 1 |
| Caspase-9 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 2 | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member C1 | 0 | 1 | 0 | 1 |
| Solute carrier family 22 member 6 | 0 | 1 | 0 | 1 |
| Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 2 |
| glp-1 receptor, partial | 2 | 0 | 0 | 2 |
| bromodomain adjacent to zinc finger domain 2B | 3 | 0 | 0 | 3 |
| thyrotropin-releasing hormone receptor | 2 | 0 | 0 | 2 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| Polyphenol oxidase 2 | 0 | 1 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 2 | 0 | 2 |
| Neuronal acetylcholine receptor subunit alpha-4 | 1 | 0 | 0 | 1 |
| Cholesteryl ester transfer protein | 0 | 1 | 0 | 1 |
| Neuronal acetylcholine receptor subunit beta-2 | 1 | 0 | 0 | 1 |
| D-amino-acid oxidase | 0 | 1 | 0 | 1 |
| Xanthine dehydrogenase/oxidase | 0 | 1 | 0 | 1 |
| Hydroxycarboxylic acid receptor 3 | 0 | 0 | 1 | 1 |
| Nicotinamidase | 0 | 1 | 0 | 1 |
| Hydroxycarboxylic acid receptor 2 | 0 | 0 | 1 | 1 |
| Hydroxycarboxylic acid receptor 2 | 0 | 2 | 1 | 3 |
| D-aspartate oxidase | 0 | 1 | 0 | 1 |
| Hydroxycarboxylic acid receptor 2 | 0 | 1 | 1 | 2 |
| nuclear receptor subfamily 1, group I, member 3 | 3 | 0 | 0 | 3 |
| Histone H2A.x | 3 | 0 | 0 | 3 |
| Caspase-7 | 2 | 0 | 0 | 2 |
| caspase-3 | 2 | 0 | 0 | 2 |
| Chain A, Ferritin light chain | 2 | 0 | 0 | 2 |
| DNA polymerase kappa isoform 1 | 2 | 0 | 0 | 2 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Cytochrome P450 3A4 | 0 | 1 | 1 | 2 |
| UDP-glucuronosyltransferase 2B7 | 0 | 0 | 0 | 1 |
| Cytochrome P450 3A5 | 0 | 1 | 0 | 1 |
| UDP-glucuronosyltransferase 1A4 | 0 | 0 | 0 | 1 |
| Serine/threonine-protein kinase mTOR | 0 | 1 | 0 | 1 |
| Spike glycoprotein | 2 | 0 | 0 | 2 |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | 0 | 2 | 1 | 3 |
| Peptidyl-prolyl cis-trans isomerase FKBP1B | 0 | 0 | 1 | 1 |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 0 | 1 | 0 | 1 |
| Peptidyl-prolyl cis-trans isomerase FKBP5 | 0 | 1 | 0 | 1 |
| Splicing factor 3B subunit 3 | 0 | 1 | 0 | 1 |
| ATPase family AAA domain-containing protein 5 | 5 | 0 | 0 | 5 |
| Ataxin-2 | 5 | 0 | 0 | 5 |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | 0 | 1 | 0 | 1 |
| Solute carrier organic anion transporter family member 1B1 | 0 | 1 | 0 | 1 |
| nuclear receptor subfamily 1, group I, member 2 | 2 | 0 | 0 | 2 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 2 | 0 | 0 | 2 |
| Retinoic acid receptor alpha | 0 | 2 | 3 | 8 |
| Retinoic acid receptor beta | 0 | 2 | 3 | 8 |
| Retinoic acid receptor gamma | 0 | 2 | 3 | 8 |
| Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
| dopamine D1 receptor | 1 | 0 | 0 | 1 |
| MSH | 0 | 0 | 0 | 1 |
| ATAD5 protein, partial | 3 | 0 | 0 | 3 |
| NFKB1 protein, partial | 2 | 0 | 0 | 2 |
| Thrombopoietin | 1 | 0 | 0 | 1 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 4 | 0 | 0 | 4 |
| nonstructural protein 1 | 2 | 0 | 0 | 2 |
| Parkin | 2 | 0 | 0 | 2 |
| arylsulfatase A | 2 | 0 | 0 | 2 |
| pyruvate kinase | 1 | 0 | 0 | 1 |
| heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1 | 0 | 0 | 1 |
| NPC intracellular cholesterol transporter 1 precursor | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 2 | 0 | 0 | 2 |
| polyunsaturated fatty acid lipoxygenase ALOX12 | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 1 precursor | 1 | 0 | 0 | 1 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
| ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
| urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
| plasminogen precursor | 1 | 0 | 0 | 1 |
| urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
| M-phase phosphoprotein 8 | 2 | 0 | 0 | 2 |
| muscleblind-like protein 1 isoform 1 | 2 | 0 | 0 | 2 |
| pyruvate kinase PKM isoform b | 1 | 0 | 0 | 1 |
| neuropeptide S receptor isoform A | 1 | 0 | 0 | 1 |
| Hematopoietic prostaglandin D synthase | 0 | 1 | 0 | 1 |
| Transient receptor potential cation channel subfamily A member 1 | 0 | 1 | 0 | 1 |
| Ornithine decarboxylase | 1 | 0 | 0 | 2 |
| NACHT, LRR and PYD domains-containing protein 3 | 0 | 1 | 0 | 1 |
| Transient receptor potential cation channel subfamily V member 2 | 0 | 1 | 0 | 1 |
| Chain A, Nuclear Receptor ROR-beta | 0 | 1 | 0 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| pregnane X receptor | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 3 | 0 | 0 | 3 |
| Ornithine decarboxylase | 0 | 0 | 0 | 1 |
| Cytochrome P450 1A2 | 0 | 0 | 1 | 1 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Adenosine receptor A3 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2D6 | 0 | 0 | 1 | 1 |
| 60 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Retinoic acid receptor alpha | 0 | 1 | 2 | 3 |
| Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
| Retinoic acid receptor gamma | 0 | 1 | 2 | 3 |
| 5-hydroxytryptamine receptor 1A | 0 | 1 | 0 | 1 |
| Retinoic acid receptor RXR-alpha | 0 | 2 | 2 | 4 |
| Retinoic acid receptor beta | 0 | 1 | 2 | 3 |
| Cellular retinoic acid-binding protein 2 | 0 | 0 | 1 | 1 |
| Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
| Mitogen-activated protein kinase 1 | 0 | 1 | 0 | 1 |
| Retinoic acid receptor RXR-alpha | 0 | 1 | 2 | 3 |
| Retinoic acid receptor RXR-beta | 0 | 2 | 2 | 4 |
| Retinoic acid receptor RXR-beta | 0 | 1 | 2 | 3 |
| Retinoic acid receptor RXR-gamma | 0 | 1 | 2 | 3 |
| Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-alpha | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 0 | 1 | 0 | 1 |
| Cellular retinoic acid-binding protein 1 | 0 | 1 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
| Retinoic acid receptor RXR-gamma | 0 | 2 | 2 | 4 |
| Nuclear receptor ROR-gamma | 0 | 1 | 1 | 2 |
| 10 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
| Cellular retinoic acid-binding protein 1 | 0 | 0 | 1 | 1 |
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 0 | 2 | 1 | 3 |
| Thiosulfate sulfurtransferase | 0 | 1 | 0 | 1 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| 10 kDa chaperonin | 0 | 1 | 0 | 1 |
| Indoleamine 2,3-dioxygenase 2 | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-beta | 0 | 1 | 0 | 1 |
| Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
| Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
| Smad3 | 1 | 0 | 0 | 1 |
| procathepsin L isoform 1 preproprotein | 0 | 1 | 0 | 1 |
| Glucocorticoid receptor | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-1 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit beta | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-2 | 0 | 4 | 0 | 4 |
| Glycine receptor subunit alpha-3 | 0 | 4 | 0 | 4 |
| TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 1 | 0 | 0 | 1 |
| caspase 7, apoptosis-related cysteine protease | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| Urease subunit alpha | 0 | 1 | 0 | 1 |
| Urease subunit beta | 0 | 1 | 0 | 1 |
| Olfactory receptor 51E2 | 0 | 0 | 1 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |