Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
Chain A, 2-oxoglutarate Oxygenase | 2 | 0 | 0 | 2 |
GLI family zinc finger 3 | 6 | 0 | 0 | 6 |
AR protein | 7 | 0 | 0 | 7 |
nuclear receptor subfamily 1, group I, member 3 | 4 | 0 | 0 | 4 |
glucocorticoid receptor [Homo sapiens] | 5 | 0 | 0 | 5 |
retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
pregnane X nuclear receptor | 4 | 0 | 0 | 4 |
cystic fibrosis transmembrane conductance regulator | 0 | 1 | 0 | 1 |
DNA polymerase beta | 1 | 0 | 0 | 1 |
short transient receptor potential channel 6 isoform 1 | 0 | 0 | 1 | 1 |
Solute carrier family 22 member 1 | 0 | 2 | 0 | 2 |
ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 3 |
5-hydroxytryptamine receptor 4 | 0 | 4 | 0 | 4 |
Bile salt export pump | 0 | 4 | 0 | 4 |
Muscarinic acetylcholine receptor M2 | 0 | 4 | 1 | 8 |
Muscarinic acetylcholine receptor M4 | 0 | 4 | 1 | 7 |
Muscarinic acetylcholine receptor M1 | 0 | 3 | 1 | 6 |
Muscarinic acetylcholine receptor M3 | 0 | 3 | 1 | 6 |
Muscarinic acetylcholine receptor M4 | 0 | 3 | 1 | 6 |
Muscarinic acetylcholine receptor M5 | 0 | 3 | 1 | 6 |
Muscarinic acetylcholine receptor M5 | 0 | 4 | 1 | 7 |
Muscarinic acetylcholine receptor M2 | 0 | 3 | 1 | 7 |
Muscarinic acetylcholine receptor M1 | 0 | 4 | 1 | 8 |
Muscarinic acetylcholine receptor M1 | 0 | 0 | 0 | 1 |
Muscarinic acetylcholine receptor M3 | 0 | 4 | 1 | 7 |
Alpha-1D adrenergic receptor | 0 | 4 | 0 | 4 |
5-hydroxytryptamine receptor 2C | 0 | 4 | 0 | 4 |
Muscarinic acetylcholine receptor M4 | 0 | 1 | 0 | 1 |
Histamine H2 receptor | 1 | 0 | 0 | 2 |
5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
Reverse transcriptase/RNaseH | 0 | 0 | 0 | 1 |
Muscarinic acetylcholine receptor | 0 | 1 | 1 | 2 |
Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
Chain A, Beta-lactamase | 3 | 0 | 0 | 3 |
interleukin 8 | 1 | 0 | 0 | 1 |
glp-1 receptor, partial | 1 | 0 | 0 | 1 |
pregnane X receptor | 2 | 0 | 0 | 2 |
RAR-related orphan receptor gamma | 4 | 0 | 0 | 4 |
ATAD5 protein, partial | 2 | 0 | 0 | 2 |
Fumarate hydratase | 2 | 0 | 0 | 2 |
NFKB1 protein, partial | 1 | 0 | 0 | 1 |
PPM1D protein | 2 | 0 | 0 | 2 |
TDP1 protein | 5 | 0 | 0 | 5 |
Thrombopoietin | 1 | 0 | 0 | 1 |
Smad3 | 1 | 0 | 0 | 1 |
aldehyde dehydrogenase 1 family, member A1 | 5 | 0 | 0 | 5 |
estrogen receptor 2 (ER beta) | 3 | 0 | 0 | 3 |
progesterone receptor | 2 | 0 | 0 | 2 |
cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
retinoic acid nuclear receptor alpha variant 1 | 5 | 0 | 0 | 5 |
estrogen-related nuclear receptor alpha | 5 | 0 | 0 | 5 |
farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
estrogen nuclear receptor alpha | 5 | 0 | 0 | 5 |
polyprotein | 2 | 0 | 0 | 2 |
67.9K protein | 1 | 0 | 0 | 1 |
Parkin | 2 | 0 | 0 | 2 |
peroxisome proliferator-activated receptor delta | 4 | 0 | 0 | 4 |
peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
vitamin D (1,25- dihydroxyvitamin D3) receptor | 4 | 0 | 0 | 4 |
arylsulfatase A | 1 | 0 | 0 | 1 |
IDH1 | 2 | 0 | 0 | 2 |
euchromatic histone-lysine N-methyltransferase 2 | 5 | 0 | 0 | 5 |
aryl hydrocarbon receptor | 3 | 0 | 0 | 3 |
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 3 | 0 | 0 | 3 |
thyroid stimulating hormone receptor | 3 | 0 | 0 | 3 |
activating transcription factor 6 | 3 | 0 | 0 | 3 |
Bloom syndrome protein isoform 1 | 2 | 0 | 0 | 2 |
peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
hemoglobin subunit beta | 1 | 0 | 0 | 1 |
cellular tumor antigen p53 isoform a | 2 | 0 | 0 | 2 |
chromobox protein homolog 1 | 5 | 0 | 0 | 5 |
thyroid hormone receptor beta isoform 2 | 5 | 0 | 0 | 5 |
huntingtin isoform 2 | 2 | 0 | 0 | 2 |
ras-related protein Rab-9A | 1 | 0 | 0 | 1 |
serine/threonine-protein kinase mTOR isoform 1 | 2 | 0 | 0 | 2 |
nuclear factor erythroid 2-related factor 2 isoform 1 | 4 | 0 | 0 | 4 |
urokinase-type plasminogen activator precursor | 1 | 0 | 0 | 1 |
plasminogen precursor | 1 | 0 | 0 | 1 |
urokinase plasminogen activator surface receptor precursor | 1 | 0 | 0 | 1 |
geminin | 4 | 0 | 0 | 4 |
peripheral myelin protein 22 | 4 | 0 | 0 | 4 |
histone acetyltransferase KAT2A isoform 1 | 3 | 0 | 0 | 3 |
muscarinic acetylcholine receptor M1 | 3 | 0 | 0 | 3 |
lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
Interferon beta | 3 | 0 | 0 | 3 |
Cellular tumor antigen p53 | 4 | 0 | 0 | 4 |
Integrin beta-3 | 1 | 0 | 0 | 1 |
Integrin alpha-IIb | 1 | 0 | 0 | 1 |
Adenosine receptor A3 | 0 | 3 | 0 | 3 |
DNA (cytosine-5)-methyltransferase 1 | 0 | 1 | 0 | 1 |
Adenosine receptor A2a | 0 | 1 | 0 | 1 |
Adenosine receptor A1 | 0 | 1 | 0 | 1 |
D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
Nuclear receptor ROR-gamma | 1 | 1 | 1 | 3 |
Spike glycoprotein | 2 | 0 | 0 | 2 |
Multidrug and toxin extrusion protein 1 | 0 | 2 | 0 | 2 |
Histone-lysine N-methyltransferase EHMT2 | 0 | 1 | 0 | 1 |
ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
Ataxin-2 | 3 | 0 | 0 | 3 |
ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
Chain A, HADH2 protein | 1 | 0 | 0 | 1 |
Chain B, HADH2 protein | 1 | 0 | 0 | 1 |
phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
regulator of G-protein signaling 4 | 2 | 0 | 0 | 2 |
EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
v-jun sarcoma virus 17 oncogene homolog (avian) | 1 | 0 | 0 | 1 |
cytochrome P450 2D6 isoform 1 | 1 | 0 | 0 | 1 |
cytochrome P450 2C19 precursor | 1 | 0 | 0 | 1 |
D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
potassium voltage-gated channel subfamily H member 2 isoform d | 2 | 0 | 0 | 2 |
atrial natriuretic peptide receptor 2 precursor | 1 | 0 | 0 | 1 |
lethal factor (plasmid) | 1 | 0 | 0 | 1 |
chaperonin GroEL | 1 | 0 | 0 | 1 |
Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
Sodium-dependent noradrenaline transporter | 0 | 1 | 0 | 1 |
Voltage-dependent calcium channel gamma-2 subunit | 2 | 0 | 0 | 2 |
Prostaglandin G/H synthase 1 | 0 | 1 | 0 | 1 |
Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
Alpha-2A adrenergic receptor | 0 | 2 | 0 | 2 |
Glycogen phosphorylase, brain form | 0 | 1 | 0 | 1 |
Glycogen phosphorylase, muscle form | 0 | 1 | 0 | 1 |
Angiotensin-converting enzyme | 0 | 2 | 0 | 2 |
D(2) dopamine receptor | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
Alpha-2B adrenergic receptor | 0 | 2 | 0 | 2 |
Alpha-2C adrenergic receptor | 0 | 2 | 0 | 2 |
D | 0 | 1 | 0 | 1 |
D(3) dopamine receptor | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 1A | 0 | 3 | 0 | 3 |
Glutamate receptor 2 | 2 | 0 | 0 | 2 |
Endothelin receptor type B | 0 | 1 | 0 | 1 |
D(1A) dopamine receptor | 0 | 2 | 0 | 2 |
UDP-glucuronosyltransferase 1A4 | 0 | 1 | 0 | 2 |
Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
Endothelin receptor type B | 0 | 1 | 0 | 1 |
Histamine H2 receptor | 0 | 2 | 0 | 2 |
D(1B) dopamine receptor | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2A | 0 | 2 | 0 | 2 |
5-hydroxytryptamine receptor 1B | 0 | 2 | 0 | 2 |
D(4) dopamine receptor | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2B | 0 | 1 | 0 | 1 |
Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 2C | 0 | 1 | 0 | 1 |
5-hydroxytryptamine receptor 7 | 0 | 1 | 0 | 1 |
Histamine H1 receptor | 0 | 2 | 1 | 3 |
D(3) dopamine receptor | 0 | 2 | 0 | 2 |
UDP-glucuronosyltransferase 1A3 | 0 | 0 | 0 | 1 |
5-hydroxytryptamine receptor 2B | 0 | 4 | 0 | 4 |
5-hydroxytryptamine receptor 6 | 0 | 2 | 0 | 2 |
D(2) dopamine receptor | 0 | 1 | 0 | 1 |
D(2) dopamine receptor | 0 | 2 | 0 | 2 |
Potassium voltage-gated channel subfamily H member 2 | 0 | 3 | 0 | 3 |
Sodium-dependent serotonin transporter | 0 | 1 | 0 | 1 |
Nuclear receptor subfamily 3 group C member 3 | 0 | 2 | 0 | 2 |
Histone-lysine N-methyltransferase SETD7 | 0 | 2 | 0 | 2 |
Transporter | 0 | 1 | 0 | 1 |
hypoxia-inducible factor 1 alpha subunit | 2 | 0 | 0 | 2 |
SMAD family member 2 | 1 | 0 | 0 | 1 |
SMAD family member 3 | 1 | 0 | 0 | 1 |
heat shock protein beta-1 | 2 | 0 | 0 | 2 |
Sex hormone-binding globulin | 0 | 0 | 1 | 1 |
Beta-glucuronidase | 0 | 1 | 0 | 1 |
Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
Beta-glucuronidase | 0 | 1 | 0 | 1 |
Glucose-6-phosphate 1-dehydrogenase | 0 | 2 | 0 | 2 |
Alpha-synuclein | 1 | 1 | 0 | 2 |
TAR DNA-binding protein 43 | 1 | 0 | 0 | 1 |
G-protein coupled bile acid receptor 1 | 0 | 0 | 1 | 1 |
Glucose-6-phosphate 1-dehydrogenase | 0 | 1 | 0 | 1 |
NPC1-like intracellular cholesterol transporter 1 | 0 | 0 | 1 | 1 |
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | 0 | 0 | 1 | 1 |
thyroid hormone receptor beta isoform a | 2 | 0 | 0 | 2 |
Carbonic anhydrase 1 | 0 | 2 | 0 | 2 |
Carbonic anhydrase 2 | 0 | 2 | 0 | 2 |
Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
Carbonic anhydrase | 0 | 2 | 0 | 2 |
Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
thioredoxin reductase | 2 | 0 | 0 | 2 |
GLS protein | 2 | 0 | 0 | 2 |
Microtubule-associated protein tau | 2 | 0 | 0 | 2 |
mitogen-activated protein kinase 1 | 1 | 0 | 0 | 1 |
flap endonuclease 1 | 1 | 0 | 0 | 1 |
cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
Gamma-aminobutyric acid receptor subunit pi | 2 | 1 | 0 | 3 |
Potassium channel subfamily K member 3 | 0 | 1 | 0 | 1 |
Potassium channel subfamily K member 2 | 0 | 1 | 0 | 1 |
Sodium channel protein type 1 subunit alpha | 0 | 1 | 0 | 1 |
Sodium channel protein type 2 subunit alpha | 0 | 1 | 0 | 1 |
Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit delta | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 1 | 0 | 3 |
Potassium voltage-gated channel subfamily A member 5 | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 1 | 0 | 3 |
Sodium channel protein type 4 subunit alpha | 0 | 1 | 0 | 1 |
Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 1 | 0 | 3 |
Sodium channel protein type 5 subunit alpha | 0 | 1 | 0 | 1 |
Sodium channel protein type 9 subunit alpha | 0 | 1 | 0 | 1 |
Potassium voltage-gated channel subfamily D member 2 | 0 | 1 | 0 | 1 |
Potassium channel subfamily K member 18 | 0 | 1 | 0 | 1 |
GABA theta subunit | 2 | 1 | 0 | 3 |
Gamma-aminobutyric acid receptor subunit epsilon | 2 | 1 | 0 | 3 |
Sodium channel protein type 3 subunit alpha | 0 | 1 | 0 | 1 |
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | 0 | 1 | 0 | 1 |
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast | 0 | 1 | 0 | 1 |
Glutathione reductase, mitochondrial | 0 | 2 | 0 | 2 |
Cationic amino acid transporter 3 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
Cytochrome P450 3A4 | 0 | 1 | 1 | 2 |
Translocator protein | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 2B7 | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 1-6 | 0 | 1 | 0 | 1 |
ATP-dependent translocase ABCB1 | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 1A1 | 0 | 1 | 0 | 1 |
UDP-glucuronosyltransferase 2B10 | 0 | 1 | 0 | 1 |
Carbonic anhydrase | 0 | 1 | 0 | 1 |
Polyphenol oxidase 2 | 0 | 1 | 0 | 1 |
Mu-type opioid receptor | 0 | 1 | 0 | 1 |
Carbonic anhydrase | 0 | 1 | 0 | 1 |
Chain A, Nuclear Receptor ROR-beta | 0 | 1 | 0 | 1 |
Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
Chain A, Cruzipain | 1 | 0 | 0 | 1 |
Luciferase | 1 | 0 | 0 | 1 |
USP1 protein, partial | 1 | 0 | 0 | 1 |
thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
nonstructural protein 1 | 1 | 0 | 0 | 1 |
G | 1 | 0 | 0 | 1 |
bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
Caspase-7 | 1 | 0 | 0 | 1 |
vitamin D3 receptor isoform VDRA | 1 | 0 | 0 | 1 |
nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
caspase-3 | 1 | 0 | 0 | 1 |
nuclear receptor ROR-gamma isoform 1 | 1 | 0 | 0 | 1 |
DNA polymerase kappa isoform 1 | 1 | 0 | 0 | 1 |
survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
Ornithine decarboxylase | 0 | 0 | 0 | 1 |
HLA class I histocompatibility antigen, B alpha chain | 1 | 0 | 0 | 1 |
Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
Cytochrome P450 1A2 | 0 | 0 | 1 | 1 |
Ornithine decarboxylase | 0 | 0 | 0 | 1 |
60 kDa chaperonin | 0 | 1 | 0 | 1 |
Retinoic acid receptor alpha | 0 | 2 | 2 | 7 |
Cytochrome P450 2D6 | 0 | 0 | 1 | 1 |
60 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
Retinoic acid receptor beta | 0 | 2 | 2 | 7 |
Retinoic acid receptor alpha | 0 | 1 | 2 | 3 |
Cytochrome P450 2C9 | 0 | 0 | 1 | 1 |
Retinoic acid receptor gamma | 0 | 2 | 2 | 7 |
Alpha-1B adrenergic receptor | 0 | 2 | 0 | 2 |
Alpha-1A adrenergic receptor | 0 | 1 | 0 | 1 |
Retinoic acid receptor gamma | 0 | 1 | 2 | 3 |
Retinoic acid receptor RXR-alpha | 0 | 2 | 2 | 4 |
Retinoic acid receptor beta | 0 | 1 | 2 | 3 |
Cellular retinoic acid-binding protein 2 | 0 | 0 | 1 | 1 |
Alpha-1D adrenergic receptor | 0 | 1 | 0 | 1 |
Mitogen-activated protein kinase 1 | 0 | 1 | 0 | 1 |
Retinoic acid receptor RXR-alpha | 0 | 1 | 2 | 3 |
Retinoic acid receptor RXR-beta | 0 | 2 | 2 | 4 |
Retinoic acid receptor RXR-beta | 0 | 1 | 2 | 3 |
Retinoic acid receptor RXR-gamma | 0 | 1 | 2 | 3 |
Indoleamine 2,3-dioxygenase 1 | 0 | 1 | 0 | 1 |
Cytochrome P450 2C19 | 0 | 0 | 1 | 1 |
Nuclear receptor ROR-alpha | 0 | 1 | 0 | 1 |
Cellular retinoic acid-binding protein 1 | 0 | 1 | 0 | 2 |
Alpha-1A adrenergic receptor | 0 | 2 | 0 | 2 |
Retinoic acid receptor RXR-gamma | 0 | 2 | 2 | 4 |
10 kDa heat shock protein, mitochondrial | 0 | 1 | 0 | 1 |
Cellular retinoic acid-binding protein 1 | 0 | 0 | 1 | 1 |
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 0 | 2 | 1 | 3 |
Thiosulfate sulfurtransferase | 0 | 1 | 0 | 1 |
60 kDa chaperonin | 0 | 1 | 0 | 1 |
10 kDa chaperonin | 0 | 1 | 0 | 1 |
Indoleamine 2,3-dioxygenase 2 | 0 | 1 | 0 | 1 |
Inositol hexakisphosphate kinase 1 | 1 | 0 | 0 | 1 |
Nuclear receptor ROR-beta | 0 | 1 | 0 | 1 |
cytochrome P450 2C9, partial | 1 | 0 | 0 | 1 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |