| Protein | Potency Measurements | Inhibition Measurements | Activation Measurements | Drugs |
|---|
| Carbonic anhydrase 1 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 2 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 4 | 0 | 1 | 0 | 1 |
| Carbonic anhydrase | 0 | 1 | 0 | 1 |
| Carbonic anhydrase 15 | 0 | 1 | 0 | 1 |
| Vasopressin V2 receptor | 0 | 1 | 1 | 2 |
| Oxytocin receptor | 0 | 0 | 1 | 1 |
| Vasopressin V1a receptor | 0 | 1 | 1 | 2 |
| Vasopressin V1b receptor | 0 | 1 | 1 | 2 |
| Translocator protein | 0 | 1 | 0 | 1 |
| Vasopressin V2 receptor | 0 | 1 | 1 | 2 |
| Chain A, TYROSYL-DNA PHOSPHODIESTERASE | 5 | 0 | 0 | 5 |
| Chain A, JmjC domain-containing histone demethylation protein 3A | 1 | 0 | 0 | 1 |
| glp-1 receptor, partial | 3 | 0 | 0 | 3 |
| RAR-related orphan receptor gamma | 6 | 0 | 0 | 6 |
| USP1 protein, partial | 5 | 0 | 0 | 5 |
| GLI family zinc finger 3 | 8 | 0 | 0 | 8 |
| thyroid stimulating hormone receptor | 6 | 0 | 0 | 6 |
| nuclear receptor subfamily 1, group I, member 3 | 5 | 0 | 0 | 5 |
| progesterone receptor | 5 | 0 | 0 | 5 |
| glucocorticoid receptor [Homo sapiens] | 6 | 0 | 0 | 6 |
| pregnane X nuclear receptor | 5 | 0 | 0 | 5 |
| estrogen nuclear receptor alpha | 9 | 0 | 0 | 9 |
| 67.9K protein | 2 | 0 | 0 | 2 |
| bromodomain adjacent to zinc finger domain 2B | 1 | 0 | 0 | 1 |
| peroxisome proliferator-activated receptor delta | 5 | 0 | 0 | 5 |
| vitamin D (1,25- dihydroxyvitamin D3) receptor | 6 | 0 | 0 | 6 |
| thyroid stimulating hormone receptor | 1 | 0 | 0 | 1 |
| v-jun sarcoma virus 17 oncogene homolog (avian) | 3 | 0 | 0 | 3 |
| chromobox protein homolog 1 | 3 | 0 | 0 | 3 |
| potassium voltage-gated channel subfamily H member 2 isoform d | 4 | 0 | 0 | 4 |
| lethal(3)malignant brain tumor-like protein 1 isoform I | 1 | 0 | 0 | 1 |
| Cathepsin B | 0 | 2 | 0 | 2 |
| Cathepsin B | 0 | 1 | 0 | 1 |
| Nuclear receptor ROR-gamma | 3 | 0 | 0 | 3 |
| Rap guanine nucleotide exchange factor 4 | 1 | 0 | 0 | 1 |
| Chain A, Sex Hormone-Binding Globulin | 0 | 0 | 1 | 1 |
| Chain A, HADH2 protein | 3 | 0 | 0 | 3 |
| Chain B, HADH2 protein | 3 | 0 | 0 | 3 |
| interleukin 8 | 3 | 0 | 0 | 3 |
| AR protein | 8 | 0 | 0 | 8 |
| estrogen receptor 2 (ER beta) | 4 | 0 | 0 | 4 |
| retinoic acid nuclear receptor alpha variant 1 | 4 | 0 | 0 | 4 |
| retinoid X nuclear receptor alpha | 5 | 0 | 0 | 5 |
| estrogen-related nuclear receptor alpha | 6 | 0 | 0 | 6 |
| cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a | 5 | 0 | 0 | 5 |
| thyrotropin-releasing hormone receptor | 1 | 0 | 0 | 1 |
| nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a | 2 | 0 | 0 | 2 |
| Histone H2A.x | 2 | 0 | 0 | 2 |
| vitamin D3 receptor isoform VDRA | 2 | 0 | 0 | 2 |
| transcriptional regulator ERG isoform 3 | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform 2 | 5 | 0 | 0 | 5 |
| nuclear factor erythroid 2-related factor 2 isoform 1 | 6 | 0 | 0 | 6 |
| geminin | 4 | 0 | 0 | 4 |
| peripheral myelin protein 22 | 4 | 0 | 0 | 4 |
| cytochrome P450 3A4 isoform 1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit pi | 2 | 0 | 0 | 2 |
| Voltage-dependent calcium channel gamma-2 subunit | 3 | 0 | 0 | 3 |
| Plasma kallikrein | 0 | 1 | 0 | 1 |
| Glucocorticoid receptor | 0 | 3 | 0 | 4 |
| Sex hormone-binding globulin | 0 | 1 | 1 | 2 |
| Progesterone receptor | 0 | 1 | 0 | 1 |
| Progesterone receptor | 0 | 1 | 1 | 2 |
| Glucocorticoid receptor | 0 | 1 | 0 | 1 |
| Corticosteroid-binding globulin | 0 | 1 | 0 | 1 |
| Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
| Sex hormone-binding globulin | 0 | 1 | 0 | 1 |
| Androgen receptor | 0 | 2 | 2 | 6 |
| Aromatase | 0 | 1 | 0 | 2 |
| Androgen receptor | 0 | 4 | 1 | 5 |
| Gamma-aminobutyric acid receptor subunit beta-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit delta | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-2 | 2 | 0 | 0 | 2 |
| Androgen receptor | 0 | 1 | 1 | 2 |
| Glutamate receptor 2 | 3 | 0 | 0 | 3 |
| Gamma-aminobutyric acid receptor subunit alpha-5 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-3 | 2 | 0 | 0 | 2 |
| Mineralocorticoid receptor | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit gamma-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-2 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-4 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit gamma-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit alpha-6 | 2 | 0 | 0 | 2 |
| Testosterone 17-beta-dehydrogenase 3 | 0 | 1 | 0 | 1 |
| Angiotensin-converting enzyme | 0 | 0 | 1 | 1 |
| Cannabinoid receptor 2 | 0 | 1 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit alpha-1 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-3 | 2 | 0 | 0 | 2 |
| Gamma-aminobutyric acid receptor subunit beta-2 | 2 | 0 | 0 | 2 |
| G-protein coupled bile acid receptor 1 | 0 | 0 | 1 | 1 |
| Muscarinic acetylcholine receptor | 0 | 1 | 1 | 2 |
| GABA theta subunit | 2 | 0 | 0 | 2 |
| Neuropeptide FF receptor 2 | 0 | 0 | 0 | 1 |
| Gamma-aminobutyric acid receptor subunit epsilon | 2 | 0 | 0 | 2 |
| ALK tyrosine kinase receptor | 0 | 1 | 0 | 1 |
| Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | 2 | 0 | 0 | 2 |
| Chain A, Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Chain A, Putative fructose-1,6-bisphosphate aldolase | 3 | 0 | 0 | 3 |
| Chain A, 2-oxoglutarate Oxygenase | 3 | 0 | 0 | 3 |
| Chain A, Ferritin light chain | 1 | 0 | 0 | 1 |
| acid sphingomyelinase | 1 | 0 | 0 | 1 |
| aldehyde dehydrogenase 1 family, member A1 | 3 | 0 | 0 | 3 |
| glucocerebrosidase | 3 | 0 | 0 | 3 |
| alpha-galactosidase | 1 | 0 | 0 | 1 |
| activating transcription factor 6 | 1 | 0 | 0 | 1 |
| lysosomal alpha-glucosidase preproprotein | 1 | 0 | 0 | 1 |
| 15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1 | 1 | 0 | 0 | 1 |
| nuclear factor erythroid 2-related factor 2 isoform 2 | 1 | 0 | 0 | 1 |
| DNA polymerase beta | 1 | 0 | 0 | 1 |
| Multidrug resistance-associated protein 4 | 0 | 3 | 0 | 4 |
| Bile salt export pump | 0 | 5 | 0 | 5 |
| Cellular tumor antigen p53 | 5 | 0 | 0 | 5 |
| Thymidylate synthase | 0 | 2 | 0 | 2 |
| Thymidylate synthase | 0 | 1 | 0 | 1 |
| Dihydrofolate reductase | 0 | 0 | 1 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 1 | 0 | 1 |
| Alpha-synuclein | 1 | 0 | 0 | 1 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Solute carrier organic anion transporter family member 1A3 | 0 | 1 | 0 | 1 |
| Folylpolyglutamate synthase, mitochondrial | 0 | 0 | 0 | 1 |
| Multidrug resistance associated protein | 0 | 0 | 0 | 1 |
| SMAD family member 2 | 3 | 0 | 0 | 3 |
| SMAD family member 3 | 3 | 0 | 0 | 3 |
| farnesoid X nuclear receptor | 4 | 0 | 0 | 4 |
| flap endonuclease 1 | 3 | 0 | 0 | 3 |
| Rap guanine nucleotide exchange factor 3 | 1 | 0 | 0 | 1 |
| Chain A, Cruzipain | 1 | 0 | 0 | 1 |
| Albumin | 0 | 1 | 0 | 1 |
| Voltage-dependent L-type calcium channel subunit alpha-1C | 0 | 1 | 0 | 1 |
| aryl hydrocarbon receptor | 2 | 0 | 0 | 2 |
| cellular tumor antigen p53 isoform a | 1 | 0 | 0 | 1 |
| Integrin beta-3 | 1 | 0 | 0 | 1 |
| Integrin alpha-IIb | 1 | 0 | 0 | 1 |
| Chain A, Beta-lactamase | 1 | 0 | 0 | 1 |
| GALC protein | 2 | 0 | 0 | 2 |
| TDP1 protein | 4 | 0 | 0 | 4 |
| Microtubule-associated protein tau | 3 | 0 | 0 | 3 |
| hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 1 | 0 | 0 | 1 |
| PINK1 | 1 | 0 | 0 | 1 |
| G | 2 | 0 | 0 | 2 |
| Parkin | 1 | 0 | 0 | 1 |
| peroxisome proliferator activated receptor gamma | 3 | 0 | 0 | 3 |
| parathyroid hormone/parathyroid hormone-related peptide receptor precursor | 1 | 0 | 0 | 1 |
| lamin isoform A-delta10 | 3 | 0 | 0 | 3 |
| Interferon beta | 2 | 0 | 0 | 2 |
| HLA class I histocompatibility antigen, B alpha chain | 2 | 0 | 0 | 2 |
| Glycine receptor subunit alpha-1 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit beta | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-2 | 0 | 2 | 0 | 2 |
| Glycine receptor subunit alpha-3 | 0 | 2 | 0 | 2 |
| Cytochrome P450 2C19 | 0 | 2 | 0 | 2 |
| Spike glycoprotein | 3 | 0 | 0 | 3 |
| Inositol hexakisphosphate kinase 1 | 2 | 0 | 0 | 2 |
| cytochrome P450 2C9, partial | 2 | 0 | 0 | 2 |
| Neuropeptide Y receptor type 1 | 0 | 2 | 0 | 2 |
| Neuropeptide Y receptor type 2 | 0 | 2 | 0 | 2 |
| acetylcholinesterase | 1 | 0 | 0 | 1 |
| thioredoxin reductase | 1 | 0 | 0 | 1 |
| phosphopantetheinyl transferase | 2 | 0 | 0 | 2 |
| ATAD5 protein, partial | 1 | 0 | 0 | 1 |
| thioredoxin glutathione reductase | 1 | 0 | 0 | 1 |
| cytochrome P450 family 3 subfamily A polypeptide 4 | 3 | 0 | 0 | 3 |
| cytochrome P450 2D6 | 2 | 0 | 0 | 2 |
| IDH1 | 1 | 0 | 0 | 1 |
| DNA polymerase iota isoform a (long) | 1 | 0 | 0 | 1 |
| DNA polymerase kappa isoform 1 | 3 | 0 | 0 | 3 |
| survival motor neuron protein isoform d | 1 | 0 | 0 | 1 |
| muscleblind-like protein 1 isoform 1 | 1 | 0 | 0 | 1 |
| streptokinase A precursor | 0 | 0 | 1 | 1 |
| lethal factor (plasmid) | 1 | 0 | 0 | 1 |
| ATP-binding cassette sub-family C member 3 | 0 | 3 | 0 | 3 |
| Bile salt export pump | 0 | 1 | 0 | 1 |
| Estrogen receptor | 0 | 0 | 1 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| 60 kDa chaperonin | 0 | 1 | 0 | 1 |
| Estrogen receptor beta | 0 | 0 | 1 | 1 |
| 10 kDa chaperonin | 0 | 1 | 0 | 1 |
| Canalicular multispecific organic anion transporter 1 | 0 | 3 | 0 | 3 |
| ATPase family AAA domain-containing protein 5 | 2 | 0 | 0 | 2 |
| Ataxin-2 | 2 | 0 | 0 | 2 |
| CDGSH iron-sulfur domain-containing protein 1 | 0 | 2 | 0 | 2 |
| Fumarate hydratase | 1 | 0 | 0 | 1 |
| GLS protein | 2 | 0 | 0 | 2 |
| polyprotein | 1 | 0 | 0 | 1 |
| euchromatic histone-lysine N-methyltransferase 2 | 3 | 0 | 0 | 3 |
| D(1A) dopamine receptor | 1 | 0 | 0 | 1 |
| Amyloid-beta precursor protein | 0 | 1 | 0 | 1 |
| Aldo-keto reductase family 1 member B1 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 2 | 1 | 4 |
| Muscarinic acetylcholine receptor M4 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M1 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M3 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M5 | 0 | 2 | 0 | 2 |
| Muscarinic acetylcholine receptor M2 | 0 | 1 | 0 | 1 |
| Muscarinic acetylcholine receptor M1 | 0 | 2 | 0 | 3 |
| Muscarinic acetylcholine receptor M3 | 0 | 2 | 0 | 2 |
| Sodium-dependent noradrenaline transporter | 0 | 2 | 0 | 2 |
| Mu-type opioid receptor | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 2 | 0 | 2 |
| 5-hydroxytryptamine receptor 2B | 0 | 2 | 0 | 2 |
| Sodium-dependent dopamine transporter | 0 | 2 | 0 | 2 |
| MBT domain-containing protein 1 | 0 | 1 | 0 | 1 |
| Lethal(3)malignant brain tumor-like protein 4 | 0 | 1 | 0 | 1 |
| Lethal(3)malignant brain tumor-like protein 3 | 0 | 1 | 0 | 1 |
| Sigma non-opioid intracellular receptor 1 | 0 | 2 | 0 | 2 |
| Lethal(3)malignant brain tumor-like protein 1 | 0 | 1 | 0 | 1 |
| endonuclease IV | 1 | 0 | 0 | 1 |
| 15-lipoxygenase, partial | 1 | 0 | 0 | 1 |
| nonstructural protein 1 | 1 | 0 | 0 | 1 |
| arylsulfatase A | 1 | 0 | 0 | 1 |
| Bloom syndrome protein isoform 1 | 1 | 0 | 0 | 1 |
| peripheral myelin protein 22 isoform 1 | 1 | 0 | 0 | 1 |
| cytochrome P450 2C19 precursor | 2 | 0 | 0 | 2 |
| M-phase phosphoprotein 8 | 1 | 0 | 0 | 1 |
| Polyunsaturated fatty acid lipoxygenase ALOX15B | 1 | 0 | 0 | 1 |
| Histamine H2 receptor | 2 | 0 | 0 | 2 |
| ATP-dependent phosphofructokinase | 2 | 0 | 0 | 2 |
| Luciferase | 3 | 0 | 0 | 3 |
| hypoxia-inducible factor 1 alpha subunit | 1 | 0 | 0 | 1 |
| Caspase-7 | 1 | 0 | 0 | 1 |
| caspase-3 | 1 | 0 | 0 | 1 |
| heat shock protein beta-1 | 1 | 0 | 0 | 1 |
| Substance-P receptor | 0 | 2 | 0 | 2 |
| Neuromedin-K receptor | 0 | 0 | 1 | 1 |
| Substance-K receptor | 0 | 1 | 1 | 2 |
| Substance-K receptor | 0 | 2 | 0 | 2 |
| Substance-P receptor | 0 | 2 | 1 | 3 |
| Neuromedin-K receptor | 0 | 1 | 1 | 2 |
| Substance-P receptor | 0 | 1 | 0 | 1 |
| Substance-K receptor | 0 | 1 | 0 | 1 |
| D(2) dopamine receptor | 0 | 0 | 1 | 1 |
| Substance-K receptor | 0 | 1 | 0 | 1 |
| Growth hormone secretagogue receptor type 1 | 0 | 0 | 1 | 1 |
| Mas-related G-protein coupled receptor member X2 | 0 | 0 | 1 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| Replicase polyprotein 1ab | 0 | 1 | 0 | 1 |
| cytochrome P450 2C9 precursor | 1 | 0 | 0 | 1 |
| thyroid hormone receptor beta isoform a | 1 | 0 | 0 | 1 |
| Endothelin-1 receptor | 0 | 2 | 0 | 2 |
| Endothelin-1 receptor | 0 | 1 | 0 | 1 |
| Chain A, ATP-DEPENDENT DNA HELICASE Q1 | 1 | 0 | 0 | 1 |
| regulator of G-protein signaling 4 | 1 | 0 | 0 | 1 |
| EWS/FLI fusion protein | 1 | 0 | 0 | 1 |
| histone-lysine N-methyltransferase 2A isoform 2 precursor | 1 | 0 | 0 | 1 |
| ATP-dependent 6-phosphofructokinase | 0 | 1 | 0 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 2 | 0 | 1 | 0 | 1 |
| Nuclear receptor subfamily 1 group I member 2 | 0 | 0 | 1 | 1 |
| Serine/threonine-protein kinase D3 | 0 | 1 | 0 | 1 |
| Protein kinase C gamma type | 0 | 1 | 0 | 1 |
| Protein kinase C beta type | 0 | 1 | 0 | 1 |
| Protein kinase C alpha type | 0 | 1 | 0 | 1 |
| Tyrosine-protein phosphatase non-receptor type 1 | 0 | 1 | 0 | 1 |
| D(3) dopamine receptor | 0 | 1 | 0 | 1 |
| Protein kinase C eta type | 0 | 1 | 0 | 1 |
| Mu-type opioid receptor | 0 | 0 | 1 | 1 |
| Delta-type opioid receptor | 0 | 0 | 1 | 1 |
| Kappa-type opioid receptor | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 2 | 0 | 1 | 1 | 2 |
| Protein kinase C iota type | 0 | 1 | 0 | 1 |
| P2X purinoceptor 1 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 1 | 0 | 0 | 1 | 1 |
| P2X purinoceptor 2 | 0 | 1 | 1 | 2 |
| P2X purinoceptor 4 | 0 | 0 | 1 | 1 |
| P2X purinoceptor 5 | 0 | 0 | 1 | 1 |
| P2X purinoceptor 6 | 0 | 0 | 1 | 1 |
| P2Y purinoceptor 4 | 0 | 0 | 1 | 1 |
| NAD-dependent protein deacetylase HST2 | 0 | 1 | 0 | 1 |
| P2X purinoceptor 3 | 0 | 0 | 1 | 1 |
| DNA-dependent protein kinase catalytic subunit | 0 | 1 | 0 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 1 | 0 | 1 | 0 | 1 |
| Inositol monophosphatase 1 | 1 | 0 | 0 | 1 |
| DNA primase | 0 | 1 | 0 | 1 |
| Protein kinase C epsilon type | 0 | 1 | 0 | 1 |
| Protein kinase C theta type | 0 | 1 | 0 | 1 |
| Protein kinase C zeta type | 0 | 1 | 0 | 1 |
| Protein kinase C delta type | 0 | 1 | 0 | 1 |
| P2Y purinoceptor 6 | 0 | 1 | 0 | 1 |
| Serine/threonine-protein kinase D1 | 0 | 1 | 0 | 1 |
| Dual specificity protein phosphatase 5 | 0 | 1 | 0 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 8 | 0 | 1 | 0 | 1 |
| RmtA | 0 | 1 | 0 | 1 |
| Reverse transcriptase/RNaseH | 0 | 1 | 0 | 1 |
| Ectonucleoside triphosphate diphosphohydrolase 3 | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase sirtuin-2 | 0 | 1 | 0 | 1 |
| NAD-dependent protein deacetylase sirtuin-1 | 0 | 1 | 0 | 1 |
| P2Y purinoceptor 11 | 0 | 1 | 1 | 2 |
| P2X purinoceptor 7 | 0 | 0 | 1 | 1 |
| Protein arginine N-methyltransferase 1 | 0 | 1 | 0 | 1 |
| P2Y purinoceptor 12 | 0 | 0 | 1 | 1 |
| NAD-dependent protein deacylase sirtuin-5, mitochondrial | 0 | 1 | 0 | 1 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |