| Assay ID | Title | Year | Journal | Article |
|---|
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1356071 | Inhibition of human EAAT3 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | 2018 | Journal of medicinal chemistry, 09-13, Volume: 61, Issue:17
| Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors. |
| AID71158 | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1 | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID339915 | Displacement of [3H]SYM2081 from rat cloned iGluR7 | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID71168 | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 3 (EAAT3) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71160 | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2 | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID1321949 | Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount method | 2016 | Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19
| β-Sulfonamido Functionalized Aspartate Analogues as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype Selectivity Profiles Arising from Subtle Structural Differences. |
| AID1321948 | Inhibition of [3H]-D-Asp uptake at human EAAT1 expressed in HEK293 cells measured after 3 mins by TopCount method | 2016 | Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19
| β-Sulfonamido Functionalized Aspartate Analogues as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype Selectivity Profiles Arising from Subtle Structural Differences. |
| AID517105 | Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting | 2010 | Journal of medicinal chemistry, Oct-14, Volume: 53, Issue:19
| Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). |
| AID74828 | Glutamate uptake inhibition assay on glutamate transporters (excitatory amino acid transporters EAAT2) stably expressed on MDCK cells before U.V radiation | 2003 | Bioorganic & medicinal chemistry letters, Mar-10, Volume: 13, Issue:5
| Synthesis and photoreactivity of caged blockers for glutamate transporters. |
| AID71164 | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 1 (EAAT1) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID339911 | Displacement of CGP-39653 from KA receptor in rat synaptosomes | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID365687 | Inhibition of [14C]glutamate uptake at human EAAT3 expressed in african green monkey COS1 cells | 2008 | Bioorganic & medicinal chemistry, Aug-15, Volume: 16, Issue:16
| Synthesis and preliminary pharmacological evaluation of novel derivatives of L-beta-threo-benzylaspartate as inhibitors of the neuronal glutamate transporter EAAT3. |
| AID71165 | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 1 (EAAT1) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71167 | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID1356069 | Inhibition of human EAAT1 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | 2018 | Journal of medicinal chemistry, 09-13, Volume: 61, Issue:17
| Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors. |
| AID1356070 | Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | 2018 | Journal of medicinal chemistry, 09-13, Volume: 61, Issue:17
| Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors. |
| AID339913 | Displacement of [3H]SYM2081 from rat cloned iGluR5 | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID71162 | Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3 | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71166 | Potency (100 uM) to induce a transport current in the absence of glutamate in oocytes expressing human excitatory amino acid transporter 2 (EAAT2) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID71169 | Potency (100 uM) to induce a transport current in the presence of glutamate in oocytes expressing human excitatory amino acid transporter 3 (EAAT3) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| AID1321950 | Inhibition of [3H]-D-Asp uptake at human EAAT3 expressed in HEK293 cells measured after 3 mins by TopCount method | 2016 | Journal of medicinal chemistry, 10-13, Volume: 59, Issue:19
| β-Sulfonamido Functionalized Aspartate Analogues as Excitatory Amino Acid Transporter Inhibitors: Distinct Subtype Selectivity Profiles Arising from Subtle Structural Differences. |
| AID1356072 | Inhibition of rat EAAT4 expressed in tsA201 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting method | 2018 | Journal of medicinal chemistry, 09-13, Volume: 61, Issue:17
| Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors. |
| AID339910 | Displacement of CGP-39653 from AMPA receptor in rat synaptosomes | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID339914 | Displacement of [3H]SYM2081 from rat cloned iGluR6 | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID339912 | Displacement of CGP-39653 from NMDA receptor in rat synaptosomes | 2008 | Journal of medicinal chemistry, Jul-24, Volume: 51, Issue:14
| Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3-oxopropyl)pentanedioic acid: a novel selective inhibitor of human excitatory amino acid transporter subtype 2. |
| AID517104 | Inhibition of human EAAC1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation counting | 2010 | Journal of medicinal chemistry, Oct-14, Volume: 53, Issue:19
| Identification of selective norbornane-type aspartate analogue inhibitors of the glutamate transporter 1 (GLT-1) from the chemical universe generated database (GDB). |
| AID1346834 | Human Excitatory amino acid transporter 3 (Glutamate transporter subfamily) | 2000 | Bioorganic & medicinal chemistry letters, Nov-06, Volume: 10, Issue:21
| Syntheses of optically pure beta-hydroxyaspartate derivatives as glutamate transporter blockers. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |